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71186-53-3,MFCD00153808
Catalog No.:AA003MPS

71186-53-3 | 5-Hydroxydecanoic acid sodium salt

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50mg
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100mg
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250mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003MPS
Chemical Name:
5-Hydroxydecanoic acid sodium salt
CAS Number:
71186-53-3
Molecular Formula:
C10H19NaO3
Molecular Weight:
210.2458
MDL Number:
MFCD00153808
SMILES:
CCCCCC(CCCC(=O)[O-])O.[Na+]
Properties
Properties
 
Form:
Solid  
MP:
155-157°C  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
139  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Skeletal muscle post-conditioning by diazoxide, anti-oxidative and anti-apoptotic mechanisms.

Journal: Molecular biology reports 20121201

Title: Levosimendan protection against kidney ischemia/reperfusion injuries in anesthetized pigs.

Journal: The Journal of pharmacology and experimental therapeutics 20120801

Title: Ischemia reperfusion injury, KATP channels, and exercise-induced cardioprotection against apoptosis.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20120801

Title: Mitochondrial K+ channels are involved in ischemic postconditioning in rat hearts.

Journal: The journal of physiological sciences : JPS 20120701

Title: Diazoxide inhibits aortic endothelial cell apoptosis in diabetic rats via activation of ERK.

Journal: Acta diabetologica 20120601

Title: Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs.

Journal: Cardiovascular drugs and therapy 20120601

Title: H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.

Journal: Cardiovascular drugs and therapy 20120601

Title: Is preconditioning by oxytocin administration mediated by iNOS and/or mitochondrial K(ATP) channel activation in the in vivo anesthetized rabbit heart?

Journal: Life sciences 20120522

Title: Hypercholesterolemia abrogates sevoflurane-induced delayed preconditioning against myocardial infarct in rats by alteration of nitric oxide synthase signaling.

Journal: Shock (Augusta, Ga.) 20120501

Title: Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120501

Title: Delayed neuroprotection induced by sevoflurane via opening mitochondrial ATP-sensitive potassium channels and p38 MAPK phosphorylation.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120401

Title: High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels.

Journal: Cardiovascular diabetology 20120101

Title: Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.

Journal: Clinical and experimental pharmacology & physiology 20111001

Title: Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes.

Journal: British journal of anaesthesia 20111001

Title: A possible subcellular mechanism underlying the 'French paradox': the opening of mitochondrial K(ATP) channels.

Journal: Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20111001

Title: Isoflurane decreases death of human embryonic stem cell-derived, transcriptional marker Nkx2.5(+) cardiac progenitor cells.

Journal: Acta anaesthesiologica Scandinavica 20111001

Title: Nicorandil preserves myocardial function following brain death in rats by mitochondrial adenosine triphosphate-sensitive potassium channel-dependent mechanism.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20110901

Title: Effects of preconditioning with sevoflurane on TNF-α-induced permeability and activation of p38 MAPK in rat pulmonary microvascular endothelial cells.

Journal: Cell biochemistry and biophysics 20110901

Title: [The effect of 5-HD on expression of PKC-alpha in rats of chronic hypoxic pulmonary hypertension].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110801

Title: ATP-dependent potassium channels and mitochondrial permeability transition pores play roles in the cardioprotection of theaflavin in young rat.

Journal: The journal of physiological sciences : JPS 20110701

Title: Mitochondrial KATP channels participate in the limitation of infarct size by cariporide.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110601

Title: Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat.

Journal: Neuroscience letters 20110516

Title: Mitochondrial uncoupling agents trigger ventricular fibrillation in isolated rat hearts.

Journal: Journal of cardiovascular pharmacology 20110401

Title: Postconditioning in focal cerebral ischemia: role of the mitochondrial ATP-dependent potassium channel.

Journal: Brain research 20110223

Title: Noninvasive delayed limb ischemic preconditioning attenuates myocardial ischemia-reperfusion injury in rats by a mitochondrial K(ATP) channel-dependent mechanism.

Journal: Physiological research 20110101

Title: Modulation of myocardial mitochondrial mechanisms during severe polymicrobial sepsis in the rat.

Journal: PloS one 20110101

Title: [Hydrogen sulfide inhibits Ca(2+)-induced mitochondrial permeability transition pore opening in adult and old rat heart].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101

Title: Effect of inhibitors of NADPH oxidase complex and mitochondrial ATP-sensitive potassium channels on generation of dopaminergic neurons from neurospheres of mesencephalic precursors.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20101201

Title: Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on delta-opioid receptor stimulation.

Journal: American journal of physiology. Heart and circulatory physiology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Postconditioning effect of granulocyte colony-stimulating factor is mediated through activation of risk pathway and opening of the mitochondrial KATP channels.

Journal: American journal of physiology. Heart and circulatory physiology 20101001

Title: Opioid peptide deltorphin II simulates the cardioprotective effect of ischemic preconditioning: role of δ₂-opioid receptors, protein kinase C, and K(ATP) channels.

Journal: Bulletin of experimental biology and medicine 20101001

Title: Late cardiac preconditioning by exercise in dogs is mediated by mitochondrial potassium channels.

Journal: Journal of cardiovascular pharmacology 20100901

Title: Mitochondria as a source of mechanical signals in cardiomyocytes.

Journal: Cardiovascular research 20100701

Title: Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100701

Title: Mitochondrial KATP channel inhibition blunts arrhythmia protection in ischemic exercised hearts.

Journal: American journal of physiology. Heart and circulatory physiology 20100701

Title: Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.

Journal: The Journal of pharmacy and pharmacology 20100701

Title: Effects of mitochondrial potassium channel and membrane potential on hypoxic human pulmonary artery smooth muscle cells.

Journal: American journal of respiratory cell and molecular biology 20100601

Title: Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits.

Journal: Journal of cardiovascular pharmacology 20100601

Title: The phosphatidylinositol-3 kinase/Akt pathway mediates geranylgeranylacetone-induced neuroprotection against cerebral infarction in rats.

Journal: Brain research 20100512

Title: Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial K(ATP) channels.

Journal: Pharmacological research 20100401

Title: Stimulation of neuronal KATP channels by cGMP-dependent protein kinase: involvement of ROS and 5-hydroxydecanoate-sensitive factors in signal transduction.

Journal: American journal of physiology. Cell physiology 20100401

Title: 5-Hydroxydecanoate and coenzyme A are inhibitors of native sarcolemmal KATP channels in inside-out patches.

Journal: Biochimica et biophysica acta 20100301

Title: Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts.

Journal: Journal of Korean medical science 20100301

Title: Variable effects of the mitoK(ATP) channel modulators diazoxide and 5-HD in ATP-depleted renal epithelial cells.

Journal: Molecular and cellular biochemistry 20100201

Title: Inhibition of oxygen consumption in skeletal muscle-derived mitochondria by pinacidil, diazoxide, and glibenclamide, but not by 5-hydroxydecanoate.

Journal: Journal of bioenergetics and biomembranes 20100201

Title: Transplantation of mesenchymal stem cells preconditioned with diazoxide, a mitochondrial ATP-sensitive potassium channel opener, promotes repair of myocardial infarction in rats.

Journal: The Tohoku journal of experimental medicine 20100201

Title: Sildenafil citrate augments myocardial protection in heart transplantation.

Journal: Transplantation 20100127

Title: Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture.

Journal: Journal of molecular and cellular cardiology 20100101

Title: Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.

Journal: Brain injury 20091201

Title: The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion.

Journal: Anesthesia and analgesia 20091101

Title: [The role of sarcolemmal and mitochondrial K(ATP)-channels in realization of the cardioprotection and antiarrhythmic effect of different regimens of hypobaric adaptation].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090801

Title: Role of mitochondrial ATP-sensitive potassium channels on fatigue in mouse muscle fibers.

Journal: Biochemical and biophysical research communications 20090717

Title: Delayed anti-arrhythmic effect of nitroglycerin in anesthetized rats: involvement of CGRP, PKC and mK ATP channels.

Journal: International journal of cardiology 20090626

Title: The ceiling effect of pharmacological postconditioning with the phytoestrogen genistein is reversed by the GSK3beta inhibitor SB 216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione] through mitochondrial ATP-dependent potassium channel opening.

Journal: The Journal of pharmacology and experimental therapeutics 20090601

Title: Activation of peripheral delta2 opioid receptors increases cardiac tolerance to ischemia/reperfusion injury Involvement of protein kinase C, NO-synthase, KATP channels and the autonomic nervous system.

Journal: Life sciences 20090508

Title: Hyperthermia-induced cardioprotection is potentiated by ischemic postconditioning in rats.

Journal: Experimental biology and medicine (Maywood, N.J.) 20090501

Title: Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.

Journal: American journal of physiology. Heart and circulatory physiology 20090501

Title: Iptakalim protects against MPP+-induced degeneration of dopaminergic neurons in association with astrocyte activation.

Journal: The international journal of neuropsychopharmacology 20090401

Title: Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R.

Journal: Shock (Augusta, Ga.) 20090301

Title: Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20090301

Title: The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels.

Journal: Basic research in cardiology 20090301

Title: [Regulation of rat airway smooth muscle cell proliferation by mitochondrial ATP-sensitive K(+) channel in asthmic rats.].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20090225

Title: Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial K(ATP) channels and reactive oxygen species.

Journal: Physiological research 20090101

Title: The mitochondrial ATP-sensitive potassium channel blocker 5-hydroxydecanoate inhibits toxicity of 6-hydroxydopamine on dopaminergic neurons.

Journal: Neurotoxicity research 20090101

Title: Impact of modulators of mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) on hypoxic pulmonary vasoconstriction.

Journal: Advances in experimental medicine and biology 20090101

Title: Oral glyburide, but not glimepiride, blocks the infarct-size limiting effects of pioglitazone.

Journal: Cardiovascular drugs and therapy 20081201

Title: Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels.

Journal: British journal of pharmacology 20081201

Title: Involvement of mitoKATP channel in protective mechanisms of cerebral ischemic tolerance.

Journal: Brain research 20081031

Title: Pre-conditioning induced by carbon monoxide provides neuronal protection against apoptosis.

Journal: Journal of neurochemistry 20081001

Title: Exogenous hydrogen sulfide postconditioning protects isolated rat hearts against ischemia-reperfusion injury.

Journal: European journal of pharmacology 20080610

Title: Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons.

Journal: Brain research 20080605

Title: Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.

Journal: Anesthesiology 20080601

Title: KATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080501

Title: Effect of diazoxide on flavoprotein oxidation and reactive oxygen species generation during ischemia-reperfusion: a study on Langendorff-perfused rat hearts using optic fibers.

Journal: American journal of physiology. Heart and circulatory physiology 20080501

Title: KATP channel openers have opposite effects on mitochondrial respiration under different energetic conditions.

Journal: Journal of cardiovascular pharmacology 20080501

Title: Morphine postconditioning protects against reperfusion injury in the isolated rat hearts.

Journal: The Journal of surgical research 20080401

Title: KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury.

Journal: Archives of pharmacal research 20080401

Title: [Effects of diazoxide on Fas/FasL protein expressions in rat myocardium suffered from long-term hypothermic preservation].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20080225

Title: Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle.

Journal: The Journal of physiology 20080215

Title: Anesthetic preconditioning confers acute cardioprotection via up-regulation of manganese superoxide dismutase and preservation of mitochondrial respiratory enzyme activity.

Journal: Shock (Augusta, Ga.) 20080201

Title: Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20080101

Title: Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.

Journal: Clinical and experimental pharmacology & physiology 20080101

Title: Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts.

Journal: Anesthesia and analgesia 20080101

Title: Preconditioning by isoflurane retains its protection against ischemia-reperfusion injury in postinfarct remodeled rat hearts.

Journal: Anesthesia and analgesia 20080101

Title: Anesthesia's effects on plasma glucose and insulin and cardiac hexokinase at similar hemodynamics and without major surgical stress in fed rats.

Journal: Anesthesia and analgesia 20080101

Title: [Cardioprotective effects of flokalin: relative role of activation of sarcolemmal and mitochondrial adenosine triphosphate-dependent potassium channels].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

Title: Selective cardiac plasma-membrane K(ATP) channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion.

Journal: European journal of pharmacology 20071222

Title: Interactions of K+ATP channel blockers with Na+/K+-ATPase.

Journal: Molecular and cellular biochemistry 20071201

Title: Na+/H+ exchanger inhibitor cariporide attenuates the mitochondrial Ca2+ overload and PTP opening.

Journal: American journal of physiology. Heart and circulatory physiology 20071201

Title: [Effect of postconditioning on rat hearts suffered from long-term hypothermic preservation].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20071101

Title: 5-Hydroxydecanoate inhibits proliferation of hypoxic human pulmonary artery smooth muscle cells by blocking mitochondrial K(ATP) channels.

Journal: Acta pharmacologica Sinica 20071001

Title: Effective pharmacotherapy against oxidative injury: alternative utility of an ATP-sensitive potassium channel opener.

Journal: Journal of cardiovascular pharmacology 20071001

Title: Systemic administration of diazoxide induces delayed preconditioning against transient focal cerebral ischemia in rats.

Journal: Brain research 20070907

Title: Mitochondria are targets for geranylgeranylacetone-induced cardioprotection against ischemia-reperfusion in the rat heart.

Journal: American journal of physiology. Heart and circulatory physiology 20070901

Title: Cardioprotective effects of stretch are mediated by activation of sarcolemmal, not mitochondrial, ATP-sensitive potassium channels.

Journal: American journal of physiology. Heart and circulatory physiology 20070801

Title: Activation of alpha1B-adrenoceptors alleviates ischemia/reperfusion injury by limitation of mitochondrial Ca2+ overload in cardiomyocytes.

Journal: Cardiovascular research 20070801

Title: Intermittent activation of bradykinin B2 receptors and mitochondrial KATP channels trigger cardiac postconditioning through redox signaling.

Journal: Cardiovascular research 20070701

Title: The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis.

Journal: Circulation 20070410

Title: Modulation of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by K(ATP) channel block.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20070301

Title: Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070201

Title: Modulation of the permeability transition pore by inhibition of the mitochondrial K(ATP) channel in liver vs. brain mitochondria.

Journal: The Journal of membrane biology 20070201

Title: The cardioprotective effect of isosteviol on rats with heart ischemia-reperfusion injury.

Journal: Life sciences 20070102

Title: Distinct KATP channels mediate the antihypertrophic effects of adenosine receptor activation in neonatal rat ventricular myocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: Diazoxide-induced respiratory inhibition - a putative mitochondrial K(ATP) channel independent mechanism of pharmacological preconditioning.

Journal: Molecular and cellular biochemistry 20070101

Title: The effects of isosteviol against myocardium injury induced by ischaemia-reperfusion in the isolated guinea pig heart.

Journal: Clinical and experimental pharmacology & physiology 20070101

Title: Effects of postconditioning of adenosine and acetylcholine on the ischemic isolated rat ventricular myocytes.

Journal: European journal of pharmacology 20061107

Title: Preconditioning modulates pulmonary endothelial dysfunction following ischemia-reperfusion injury in the rat lung: role of potassium channels.

Journal: Life sciences 20061102

Title: Opening mitoKATP increases superoxide generation from complex I of the electron transport chain.

Journal: American journal of physiology. Heart and circulatory physiology 20061101

Title: Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation.

Journal: Cardiovascular research 20061101

Title: [The protective role and the mechanisms of puerarin on isolated rat heart during ischemia/reperfusion].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20061101

Title: Diazoxide-induced cardioprotection via DeltaPsim loss depending on timing of application.

Journal: Life sciences 20061012

Title: Diazoxide protects against methylmalonate-induced neuronal toxicity.

Journal: Experimental neurology 20060901

Title: Blocking cardiac ATP-sensitive K+ channels reduces hydroxyl radicals caused by potassium chloride-induced depolarization in the rat myocardium.

Journal: Analytical biochemistry 20060901

Title: K+-independent actions of diazoxide question the role of inner membrane KATP channels in mitochondrial cytoprotective signaling.

Journal: The Journal of biological chemistry 20060818

Title: The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat.

Journal: Shock (Augusta, Ga.) 20060801

Title: Inhibition of cardiac contractility by 5-hydroxydecanoate and tetraphenylphosphonium ion: a possible role of mitoKATP in response to inotropic stress.

Journal: American journal of physiology. Heart and circulatory physiology 20060701

Title: Atractyloside and 5-hydroxydecanoate block the protective effect of puerarin in isolated rat heart.

Journal: Life sciences 20060613

Title: Mitochondrial potassium ATP channels and retinal ischemic preconditioning.

Journal: Investigative ophthalmology & visual science 20060501

Title: Effects of the blockade of cardiac sarcolemmal ATP-sensitive potassium channels on arrhythmias and coronary flow in ischemia-reperfusion model in isolated rat hearts.

Journal: Vascular pharmacology 20060401

Title: MitoK(ATP)-dependent changes in mitochondrial volume and in complex II activity during ischemic and pharmacological preconditioning of Langendorff-perfused rat heart.

Journal: Journal of bioenergetics and biomembranes 20060401

Title: Myocardial ischemia tolerance in the newborn rat involving opioid receptors and mitochondrial K+ channels.

Journal: The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 20060301

Title: The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells.

Journal: Neuroscience letters 20060213

Title: Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats.

Journal: The international journal of neuropsychopharmacology 20060201

Title: Reduction of infarct size with D-myo-inositol trisphosphate: role of PI3-kinase and mitochondrial K(ATP) channels.

Journal: American journal of physiology. Heart and circulatory physiology 20060201

Title: Isoflurane and sevoflurane during reperfusion prevent recovery from ischaemia in mitochondrial KATP channel blocker pretreated hearts.

Journal: European journal of anaesthesiology 20060201

Title: Early pharmacological preconditioning by erythropoietin mediated by inducible NOS and mitochondrial ATP-dependent potassium channels in the rat heart.

Journal: Fundamental & clinical pharmacology 20060201

Title: Reduction of myocardial infarct size by tetrahydrobiopterin: possible involvement of mitochondrial KATP channels activation through nitric oxide production.

Journal: Journal of cardiovascular pharmacology 20060201

Title: Initiation of remote microvascular preconditioning requires K(ATP) channel activity.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: The direct physiological effects of mitoK(ATP) opening on heart mitochondria.

Journal: American journal of physiology. Heart and circulatory physiology 20060101

Title: Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury--Evidence for a role of K ATP channels.

Journal: Basic research in cardiology 20060101

Title: Hyperkalemic cardioplegia-induced myocyte swelling and contractile dysfunction: prevention by diazoxide.

Journal: The Annals of thoracic surgery 20060101

Title: The role of ATP sensitive K+ channels and of nitric oxide synthase on myocardial ischemia/reperfusion-induced apoptosis.

Journal: Acta histochemica 20060101

Title: Role of oxidative/nitrosative stress in the tolerance to ischemia/reperfusion injury in cardiomyopathic hamster heart.

Journal: Antioxidants & redox signaling 20060101

Title: A role of opening of mitochondrial ATP-sensitive potassium channels in the infarct size-limiting effect of ischemic preconditioning via activation of protein kinase C in the canine heart.

Journal: Biochemical and biophysical research communications 20051223

Title: Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat.

Journal: The Journal of physiology 20051215

Title: Nicorandil inhibits serum starvation-induced apoptosis in vascular endothelial cells.

Journal: Journal of cardiovascular pharmacology 20051201

Title: Protective effect of KR-31378 on oxidative stress in cardiac myocytes.

Journal: Archives of pharmacal research 20051201

Title: Lack of manifestations of diazoxide/5-hydroxydecanoate-sensitive KATP channel in rat brain nonsynaptosomal mitochondria.

Journal: The Journal of physiology 20051001

Title: Overexpression of heat-shock protein 20 in rat heart myogenic cells confers protection against simulated ischemia/reperfusion injury.

Journal: Acta pharmacologica Sinica 20050901

Title: Pharmacological preconditioning with bradykinin affords myocardial protection through NO-dependent mechanisms.

Journal: International heart journal 20050901

Title: Effects of 5-hydroxydecanoate and ischemic preconditioning on the ischemic-reperfused heart of fed and fasted rats.

Journal: Journal of physiology and biochemistry 20050901

Title: 2-(1-Hexyn-1-yl)adenosine-induced intraocular hypertension is mediated via K+ channel opening through adenosine A2A receptor in rabbits.

Journal: European journal of pharmacology 20050822

Title: Short-term caloric restriction improves ischemic tolerance independent of opening of ATP-sensitive K+ channels in both young and aged hearts.

Journal: Journal of molecular and cellular cardiology 20050801

Title: MitoKATP-channel opener protects against neuronal death in rat venous ischemia.

Journal: Neurosurgery 20050801

Title: Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria.

Journal: Brain research bulletin 20050730

Title: Is the sarcolemmal or mitochondrial K(ATP) channel activation important in the antiarrhythmic and cardioprotective effects during acute ischemia/reperfusion in the intact anesthetized rabbit model?

Journal: Life sciences 20050729

Title: Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets.

Journal: American journal of physiology. Heart and circulatory physiology 20050701

Title: Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia.

Journal: British journal of pharmacology 20050601

Title: Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.

Journal: Hypertension (Dallas, Tex. : 1979) 20050501

Title: Properties of BK(Ca) channels in oral keratinocytes.

Journal: Journal of dental research 20050501

Title: mitoKATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways.

Journal: American journal of physiology. Heart and circulatory physiology 20050401

Title: Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide.

Journal: Hypertension (Dallas, Tex. : 1979) 20050301

Title: Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning.

Journal: The Journal of pharmacology and experimental therapeutics 20050201

Title: Mitochondrial K(ATP) channels in respiratory neurons and their role in the hypoxic facilitation of rhythmic activity.

Journal: Brain research 20050201

Title: Mitochondrial Ca2+-activated K+ channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A.

Journal: Circulation 20050118

Title: 5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids.

Journal: The Journal of physiology 20050115

Title: Sarcolemmal KATP channel triggers delayed ischemic preconditioning in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20050101

Title: KR-31378, a novel benzopyran analog, attenuates hypoxia-induced cell death via mitochondrial KATP channel and protein kinase C-epsilon in heart-derived H9c2 cells.

Journal: European journal of pharmacology 20041203

Title: Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB.

Journal: The Journal of biological chemistry 20041105

Title: Inhibition of phenylephrine induced hypertrophy in rat neonatal cardiomyocytes by the mitochondrial KATP channel opener diazoxide.

Journal: Journal of molecular and cellular cardiology 20041101

Title: Sevoflurane-induced preconditioning of rat brain in vitro and the role of KATP channels.

Journal: Brain research 20040917

Title: Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways.

Journal: Journal of the American College of Cardiology 20040901

Title: Donor heart preservation with pinacidil: the role of the mitochondrial K ATP channel.

Journal: The Annals of thoracic surgery 20040801

Title: Protein kinase C-epsilon primes the cardiac sarcolemmal adenosine triphosphate-sensitive potassium channel to modulation by isoflurane.

Journal: Anesthesiology 20040801

Title: Effect of classic preconditioning and diazoxide on endothelial function and O2- and NO generation in the post-ischemic guinea-pig heart.

Journal: Cardiovascular research 20040701

Title: Ischemic preconditioning prevents reperfusion heart injury in cardiac hypertrophy by activation of mitochondrial KATP channels.

Journal: International journal of cardiology 20040701

Title: Adenosine A(1) receptor antagonist and mitochondrial ATP-sensitive potassium channel blocker attenuate the tolerance to focal cerebral ischemia in rats.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040701

Title: The human mitochondrial KATP channel is modulated by calcium and nitric oxide: a patch-clamp approach.

Journal: Biochimica et biophysica acta 20040512

Title: Sevoflurane depolarizes pre-synaptic mitochondria in the central nervous system.

Journal: Acta anaesthesiologica Scandinavica 20040501

Title: Sublethal simulated ischemia promotes delayed resistance against ischemia via ATP-sensitive (K+) channels in murine myocytes: role of PKC and iNOS.

Journal: Antioxidants & redox signaling 20040401

Title: Retinal ganglion cell survival is enhanced by gabapentin-lactam in vitro: evidence for involvement of mitochondrial KATP channels.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20040301

Title: Desflurane-induced preconditioning alters calcium-induced mitochondrial permeability transition.

Journal: Anesthesiology 20040301

Title: Delayed preconditioning of the human myocardium: signal transduction and clinical implications.

Journal: Cardiovascular research 20040215

Title: Nicorandil attenuates the mitochondrial Ca2+ overload with accompanying depolarization of the mitochondrial membrane in the heart.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040201

Title: Endothelial nitric oxide synthase overexpression attenuates myocardial reperfusion injury.

Journal: American journal of physiology. Heart and circulatory physiology 20040101

Title: Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart.

Journal: Acta pharmacologica Sinica 20040101

Title: Effects of barium and 5-hydroxydecanoate on the electrophysiologic response to acute regional ischemia and reperfusion in rat hearts.

Journal: Molecular and cellular biochemistry 20031201

Title: Nicorandil prevents oxidative stress-induced apoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels.

Journal: Brain research 20031114

Title: Early biochemical and histological alterations in rat corticoencephalic cell cultures following metabolic damage and treatment with modulators of mitochondrial ATP-sensitive potassium channels.

Journal: Neurochemistry international 20031101

Title: Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons.

Journal: Journal of neurochemistry 20031101

Title: Protection of myocardium by cyclosporin A and insulin: in vitro simulated ischemia study in human myocardium.

Journal: The Annals of thoracic surgery 20031001

Title: Sevoflurane confers additional cardioprotection after ischemic late preconditioning in rabbits.

Journal: Anesthesiology 20030901

Title: Selective ATP-sensitive potassium channel openers: fact or fiction.

Journal: Journal of molecular and cellular cardiology 20030901

Title: P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.

Journal: Journal of molecular and cellular cardiology 20030901

Title: Protective effects of the potassium channel opener-diazoxide against injury in neonatal rat ventricular myocytes.

Journal: General physiology and biophysics 20030901

Title: Lidocaine attenuates cytokine-induced cell injury in endothelial and vascular smooth muscle cells.

Journal: Anesthesia and analgesia 20030801

Title: Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death.

Journal: Journal of neurochemistry 20030801

Title: Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule.

Journal: Circulation research 20030725

Title: ATP-dependent potassium channels involved in the cardiac protection induced by intermittent hypoxia against ischemia/reperfusion injury.

Journal: Life sciences 20030725

Title: Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels.

Journal: Life sciences 20030704

Title: Mechanisms of sevoflurane-induced myocardial preconditioning in isolated human right atria in vitro.

Journal: Anesthesiology 20030701

Title: Ischaemic preconditioning and a mitochondrial KATP channel opener both produce cardioprotection accompanied by F1F0-ATPase inhibition in early ischaemia.

Journal: Basic research in cardiology 20030701

Title: Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression.

Journal: The Journal of physiology 20030615

Title: Mitochondrial K ATP channel activation is important in the antiarrhythmic and cardioprotective effects of non-hypotensive doses of nicorandil and cromakalim during ischemia/reperfusion: a study in an intact anesthetized rabbit model.

Journal: Pharmacological research 20030601

Title: Mitochondrial ATP-sensitive potassium channel: a novel site for neuroprotection.

Journal: Investigative ophthalmology & visual science 20030601

Title: Quinaprilat reduces myocardial infarct size involving nitric oxide production and mitochondrial KATP channel in rabbits.

Journal: Journal of cardiovascular pharmacology 20030601

Title: K-ATP channel independent effects of pinacidil on ATP production in isolated cardiomyocyte or pancreatic beta-cell mitochondria.

Journal: Biochemical pharmacology 20030601

Title: Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.

Journal: Cardiovascular research 20030601

Title: Cardioselective anti-ischemic ATP-sensitive potassium channel (KATP) openers: benzopyranyl indoline and indole analogues.

Journal: European journal of medicinal chemistry 20030501

Title: Modulation of slow waves by hyperpolarization with potassium channel openers in antral smooth muscle of the guinea-pig stomach.

Journal: The Journal of physiology 20030401

Title: Opening of mitochondrial ATP-sensitive potassium channels is a trigger of 3-nitropropionic acid-induced tolerance to transient focal cerebral ischemia in rats.

Journal: Stroke 20030401

Title: Targeting nucleotide-requiring enzymes: implications for diazoxide-induced cardioprotection.

Journal: American journal of physiology. Heart and circulatory physiology 20030401

Title: Beta-oxidation of 5-hydroxydecanoate, a putative blocker of mitochondrial ATP-sensitive potassium channels.

Journal: The Journal of physiology 20030301

Title: Effective protection by NHE-1 inhibition in ischemic and reperfused heart under preconditioning blockade.

Journal: American journal of physiology. Heart and circulatory physiology 20030301

Title: Oral nicorandil recaptures the waned protection from preconditioning in vivo.

Journal: British journal of pharmacology 20030301

Title: Selective mitochondrial KATP channel activation by nicorandil and 3-pyridyl pinacidil results in antiarrhythmic effect in an anesthetized rabbit model of myocardial ischemia/reperfusion.

Journal: Methods and findings in experimental and clinical pharmacology 20030301

Title: Mitochondrial KATP channel-dependent and -independent phases of ischemic preconditioning against myocardial infarction in the rat.

Journal: Basic research in cardiology 20030201

Title: Mitochondrial K(ATP) channels and sarcoplasmic reticulum influence cardiac force development under anoxia in the Amazonian armored catfish Liposarcus pardalis.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030201

Title: Preconditioning with sevoflurane reduces changes in nicotinamide adenine dinucleotide during ischemia-reperfusion in isolated hearts: reversal by 5-hydroxydecanoic acid.

Journal: Anesthesiology 20030201

Title: Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels.

Journal: Stroke 20030101

Title: Cardiomyocyte mitochondrial KATP channels participate in the antiarrhythmic and antiinfarct effects of KATP activators during ischemia and reperfusion in an intact anesthetized rabbit model.

Journal: Polish journal of pharmacology 20030101

Title: [The role of opiate receptors and ATP-dependent potassium channels of mitochondria in the formation of myocardial adaptive resistance to the arrhythmogenic effect of ischemia and reperfusion].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20030101

Title: The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration.

Journal: The Journal of physiology 20021215

Title: The role of mitochondrial K(ATP) channels in the antiarrhythmic effects of ischaemic preconditioning in dogs.

Journal: British journal of pharmacology 20021201

Title: The role of mitochondrial K(ATP) channels in antiarrhythmic effects of ischaemic preconditioning in dogs.

Journal: British journal of pharmacology 20021201

Title: Anesthetic preconditioning attenuates mitochondrial Ca2+ overload during ischemia in Guinea pig intact hearts: reversal by 5-hydroxydecanoic acid.

Journal: Anesthesia and analgesia 20021201

Title: Infarct size limitation by nicorandil: roles of mitochondrial K(ATP) channels, sarcolemmal K(ATP) channels, and protein kinase C.

Journal: Journal of the American College of Cardiology 20021016

Title: The role of serotonin in ischemic cellular damage and the infarct size-reducing effect of sarpogrelate, a 5-hydroxytryptamine-2 receptor blocker, in rabbit hearts.

Journal: Journal of the American College of Cardiology 20021002

Title: Cardioprotection by multiple preconditioning cycles does not require mitochondrial K(ATP) channels in pigs.

Journal: American journal of physiology. Heart and circulatory physiology 20021001

Title: Ischemic preconditioning in chronically hypoxic neonatal rat heart.

Journal: Pediatric research 20021001

Title: Ischemic preconditioning changes the pattern of coronary reactive hyperemia regardless of mitochondrial ATP-sensitive K(+) channel blockade.

Journal: Life sciences 20020927

Title: Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?

Journal: Cardiovascular research 20020815

Title: Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.

Journal: Cardiovascular research 20020815

Title: Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene.

Journal: Cardiovascular research 20020815

Title: Exercise induces early and late myocardial preconditioning in dogs.

Journal: Cardiovascular research 20020815

Title: Effects of mitochondrial K(ATP) modulators on cardioprotection induced by chronic high altitude hypoxia in rats.

Journal: Cardiovascular research 20020815

Title: Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel.

Journal: Cardiovascular research 20020815

Title: Ischemic preconditioning protection against stunning in conscious diabetic sheep: role of glucose, insulin, sarcolemmal and mitochondrial KATP channels.

Journal: Cardiovascular research 20020815

Title: The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.

Journal: Cardiovascular research 20020815

Title: K(ATP) channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart.

Journal: The Journal of physiology 20020801

Title: Delayed cardioprotection by isoflurane: role of K(ATP) channels.

Journal: American journal of physiology. Heart and circulatory physiology 20020701

Title: Opening of mitochondrial K(ATP) channel occurs downstream of PKC-epsilon activation in the mechanism of preconditioning.

Journal: American journal of physiology. Heart and circulatory physiology 20020701

Title: Mitochondrial ATP-sensitive K+ channels influence force development and anoxic contractility in a flatfish, yellowtail flounder Limanda ferruginea, but not Atlantic cod Gadus morhua heart.

Journal: The Journal of experimental biology 20020501

Title: Opening of mitochondrial ATP-sensitive potassium channels evokes oxygen radical generation in rabbit heart slices.

Journal: Journal of biochemistry 20020501

Title: A1 adenosine receptor overexpression decreases stunning from anoxia-reoxygenation: role of the mitochondrial K(ATP) channel.

Journal: Basic research in cardiology 20020501

Title: Preconditioning blocks cardiocyte apoptosis: role of K(ATP) channels and PKC-epsilon.

Journal: American journal of physiology. Heart and circulatory physiology 20020401

Title: H(2)O(2) opens mitochondrial K(ATP) channels and inhibits GABA receptors via protein kinase C-epsilon in cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20020401

Title: Differential effects of sarcolemmal and mitochondrial K(ATP) channels activated by 17 beta-estradiol on reperfusion arrhythmias and infarct sizes in canine hearts.

Journal: The Journal of pharmacology and experimental therapeutics 20020401

Title: The role of mitochondrial and sarcolemmal K(ATP) channels in canine ethanol-induced preconditioning in vivo.

Journal: Anesthesia and analgesia 20020401

Title: Spontaneous electrical activity and associated changes in calcium concentration in guinea-pig gastric smooth muscle.

Journal: The Journal of physiology 20020401

Title: Diazoxide protects the rabbit heart following cardioplegic ischemia.

Journal: Molecular and cellular biochemistry 20020401

Title: Selective mitochondrial K(ATP) channel activation results in antiarrhythmic effect during experimental myocardial ischemia/reperfusion in anesthetized rabbits.

Journal: European journal of pharmacology 20020222

Title: Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice.

Journal: The Journal of clinical investigation 20020215

Title: Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation.

Journal: American journal of physiology. Heart and circulatory physiology 20020201

Title: Delayed preconditioning induced by lipoteichoic acid from B. subtilis and S. aureus is not blocked by administration of 5-hydroxydecanoate.

Journal: Shock (Augusta, Ga.) 20020101

Title: Mechanisms of delayed preconditioning with A1 adenosine receptor activation in porcine coronary smooth muscle cells.

Journal: Polish journal of pharmacology 20020101

Title: Characteristics and superoxide-induced activation of reconstituted myocardial mitochondrial ATP-sensitive potassium channels.

Journal: Circulation research 20011207

Title: B16-BL6 melanoma cells release inhibitory factor(s) of active pump activity in isolated lymph vessels.

Journal: American journal of physiology. Cell physiology 20011201

Title: Distinct myoprotective roles of cardiac sarcolemmal and mitochondrial KATP channels during metabolic inhibition and recovery.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011201

Title: Anesthetic effects on mitochondrial ATP-sensitive K channel.

Journal: Anesthesiology 20011201

Title: Opening of mitochondrial K(ATP) channels attenuates the ouabain-induced calcium overload in mitochondria.

Journal: Circulation research 20011109

Title: Mitochondrial ATP-sensitive potassium channels attenuate matrix Ca(2+) overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection.

Journal: Circulation research 20011109

Title: Effects of administration of nicorandil or bimakalim prior to and during ischemia or reperfusion on survival rate, ischemia/reperfusion-induced arrhythmias and infarct size in anesthetized rabbits.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20011101

Title: Acute alcohol-induced protection against infarction in rabbit hearts: differences from and similarities to ischemic preconditioning.

Journal: Journal of molecular and cellular cardiology 20011101

Title: Mitochondrial K(ATP) channel as an end effector of cardioprotection during late preconditioning: triggering role of nitric oxide.

Journal: Journal of molecular and cellular cardiology 20011101

Title: Dual signaling via protein kinase C and phosphatidylinositol 3'-kinase/Akt contributes to bradykinin B2 receptor-induced cardioprotection in guinea pig hearts.

Journal: Journal of molecular and cellular cardiology 20011101

Title: Ischemic and pharmacological preconditioning in Girardi cells and C2C12 myotubes induce mitochondrial uncoupling.

Journal: Circulation research 20011026

Title: Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain.

Journal: The Journal of biological chemistry 20010907

Title: Mitochondrial K(ATP) channel activation reduces anoxic injury by restoring mitochondrial membrane potential.

Journal: American journal of physiology. Heart and circulatory physiology 20010901

Title: Mitochondrial K(ATP) channel opening protects a human atrial-derived cell line by a mechanism involving free radical generation.

Journal: Cardiovascular research 20010901

Title: The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes.

Journal: Journal of molecular and cellular cardiology 20010901

Title: Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction.

Journal: Basic research in cardiology 20010901

Title: Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial K(ATP) channels.

Journal: Circulation research 20010803

Title: Combination of miglitol, an anti-diabetic drug, and nicorandil markedly reduces myocardial infarct size through opening the mitochondrial K(ATP) channels in rabbits.

Journal: British journal of pharmacology 20010801

Title: Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells.

Journal: Circulation research 20010622

Title: Role of intracellular Na(+) kinetics in preconditioned rat heart.

Journal: Circulation research 20010608

Title: Pharmacologic characterization of BMS-191095, a mitochondrial K(ATP) opener with no peripheral vasodilator or cardiac action potential shortening activity.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: Activation of the adenosine triphosphate sensitive mitochondrial potassium channel is involved in the cardioprotective effect of isoflurane.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20010601

Title: Signal transduction of opioid-induced cardioprotection in ischemia-reperfusion.

Journal: Anesthesiology 20010601

Title: Preconditioning limits mitochondrial Ca(2+) during ischemia in rat hearts: role of K(ATP) channels.

Journal: American journal of physiology. Heart and circulatory physiology 20010501

Title: Chemical preconditioning with 3-nitropropionic acid in hearts: role of mitochondrial K(ATP) channel.

Journal: American journal of physiology. Heart and circulatory physiology 20010501

Title: Sevoflurane protects stunned myocardium through activation of mitochondrial ATP-sensitive potassium channels.

Journal: Anesthesia and analgesia 20010501

Title: Sarcolemmal and mitochondrial K(atp)channels mediate cardioprotection in chronically hypoxic hearts.

Journal: Journal of molecular and cellular cardiology 20010501

Title: Additive protective effects of late and early ischaemic preconditioning are mediated by the opening of KATP channels in vivo.

Journal: Pflugers Archiv : European journal of physiology 20010501

Title: Opening of mitochondrial K(ATP) channels triggers cardioprotection. Are reactive oxygen species involved?

Journal: Circulation research 20010427

Title: Late preconditioning in rat retina: involvement of adenosine and ATP-sensitive K(+) channel.

Journal: European journal of pharmacology 20010420

Title: Mitochondrial K(ATP)channel opening during index ischemia and following myocardial reperfusion in ischemic rat hearts.

Journal: Journal of molecular and cellular cardiology 20010401

Title: A(1) or A(3) adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms.

Journal: Circulation research 20010316

Title: Potassium channel openers depolarize hippocampal mitochondria.

Journal: Brain research 20010216

Title: Morphine mimics preconditioning via free radical signals and mitochondrial K(ATP) channels in myocytes.

Journal: Circulation 20010116

Title: Direct activation of mitochondrial K(ATP) channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts.

Journal: Cardiovascular research 20010101

Title: Role of mitochondrial and sarcolemmal K(ATP) channels in ischemic preconditioning of the canine heart.

Journal: American journal of physiology. Heart and circulatory physiology 20010101

Title: Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.

Journal: Journal of molecular and cellular cardiology 20010101

Title: Mitochondrial ATP dependent potassium channels mediate non-ischemic preconditioning by tachycardia in dogs.

Journal: Molecular and cellular biochemistry 20010101

Title: Congna Zi, et al. Penehyclidine hydrochloride protects against anoxia/reoxygenation injury in cardiomyocytes through ATP-sensitive potassium channels, and the Akt/GSK-3β and Akt/mTOR signaling pathways. Cell Biol Int. 2020 Jun;44(6):1353-1362.

Title: Xiantao Li, et al. 5-Hydroxydecanoate and coenzyme A are inhibitors of native sarcolemmal KATP channels in inside-out patches. Biochim Biophys Acta. 2010 Mar;1800(3):385-91.

Title: M G Marina Prendes, et al. Effects of 5-hydroxydecanoate and ischemic preconditioning on the ischemic-reperfused heart of fed and fasted rats. J Physiol Biochem. 2005 Sep;61(3):447-56.

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Tags:71186-53-3 Molecular Formula|71186-53-3 MDL|71186-53-3 SMILES|71186-53-3 5-Hydroxydecanoic acid sodium salt