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712-30-1,MFCD00038691
Catalog No.:AA005WAK

712-30-1 | 2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde

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50mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005WAK
Chemical Name:
2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde
CAS Number:
712-30-1
Molecular Formula:
C7H5N5O2
Molecular Weight:
191.1469
MDL Number:
MFCD00038691
SMILES:
O=Cc1cnc2c(n1)c(O)nc(n2)N
Properties
Properties
 
BP:
489.1°C at 760 mmHg  
Form:
Solid  
MP:
280 °C (decomp)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
303  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-1.6  

Literature

Title: Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.

Journal: The Journal of experimental medicine 20131021

Title: MR1 presents microbial vitamin B metabolites to MAIT cells.

Journal: Nature 20121129

Title: Photosensitizing properties of biopterin and its photoproducts using 2'-deoxyguanosine 5'-monophosphate as an oxidizable target.

Journal: Physical chemistry chemical physics : PCCP 20120907

Title: Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity.

Journal: ASN neuro 20120101

Title: Regulation of xanthine oxidase activity by substrates at active sites via cooperative interactions between catalytic subunits: implication to drug pharmacokinetics.

Journal: Current medicinal chemistry 20110101

Title: The self-organizing fractal theory as a universal discovery method: the phenomenon of life.

Journal: Theoretical biology & medical modelling 20110101

Title: Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells.

Journal: Journal of experimental & clinical cancer research : CR 20110101

Title: Mechanism of photooxidation of folic acid sensitized by unconjugated pterins.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20101201

Title: Substituent effects of pterin derivatives on singlet oxygen scavenging activity.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation.

Journal: PloS one 20100101

Title: Mechanism of Substrate and Inhibitor Binding of Rhodobacter capsulatus Xanthine Dehydrogenase.

Journal: The Journal of biological chemistry 20090327

Title: New results on the photochemistry of biopterin and neopterin in aqueous solution.

Journal: Photochemistry and photobiology 20090101

Title: Reactive oxygen species generation through NADH oxidation by pterin derivatives.

Journal: Nucleic acids symposium series (2004) 20080101

Title: Lipoic acid and 6-formylpterin reduce potentiation of noise-induced hearing loss by carbon monoxide: preliminary investigation.

Journal: Journal of rehabilitation research and development 20080101

Title: Inhibitory effect of 6-formylpterin on HIF-1alpha protein accumulation.

Journal: Biological & pharmaceutical bulletin 20071101

Title: Synthesis of 6-formylpterin nucleoside analogs and their ROS generation activities in the presence of NADH in the dark.

Journal: Organic & biomolecular chemistry 20071021

Title: Folate salvage in plants: pterin aldehyde reduction is mediated by multiple non-specific aldehyde reductases.

Journal: The Plant journal : for cell and molecular biology 20070801

Title: Singlet oxygen (O2(1Deltag)) quenching by dihydropterins.

Journal: The journal of physical chemistry. A 20070524

Title: Pterin and folate salvage. Plants and Escherichia coli lack capacity to reduce oxidized pterins.

Journal: Plant physiology 20070301

Title: Reactive oxygen species generation through NADH oxidation by 6-formylpterin derivatives in the dark.

Journal: Biochemical and biophysical research communications 20070223

Title: Gene expression in enhanced apoptosis of human lymphoma U937 cells treated with the combination of different free radical generators and hyperthermia.

Journal: Free radical research 20070101

Title: Comparative genomics of bacterial and plant folate synthesis and salvage: predictions and validations.

Journal: BMC genomics 20070101

Title: Chemical natures of 6-formylpterin nucleoside analogs.

Journal: Nucleic acids symposium series (2004) 20070101

Title: Folic acid as a Fenton-modulator: possible physiological implication.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20060701

Title: Novel 6-formylpterin derivatives: chemical synthesis and O2 to ROS conversion activities.

Journal: Organic & biomolecular chemistry 20060507

Title: Chemical natures and application of 6-formylpterin derivatives.

Journal: Nucleic acids symposium series (2004) 20060101

Title: Protective effects of intracellular reactive oxygen species generated by 6-formylpterin on tumor necrosis factor-alpha-induced apoptotic cell injury in cultured rat hepatocytes.

Journal: Life sciences 20050708

Title: Ultraviolet photodegradation of folic acid.

Journal: Journal of photochemistry and photobiology. B, Biology 20050701

Title: A hydrogen peroxide-generating agent, 6-formylpterin, enhances heat-induced apoptosis.

Journal: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20050501

Title: Hydrogen bond removal of pterin derivative whose structure is similar to nucleic acid bases.

Journal: Nucleic acids symposium series (2004) 20050101

Title: Cooperative catalysis in the homodimer subunits of xanthine oxidase.

Journal: Biochemistry 20040427

Title: Enhancement of radiation-induced apoptosis by 6-formylpterin.

Journal: Free radical research 20040401

Title: Effects of intracellular reactive oxygen species generated by 6-formylpterin on T cell functions.

Journal: Biochemical pharmacology 20040315

Title: Quenching of the fluorescence of pterin derivatives by anions.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040201

Title: 6-Formylpterin protects retinal neurons from transient ischemia-reperfusion injury in rats: a morphological and immunohistochemical study.

Journal: Neuropathology : official journal of the Japanese Society of Neuropathology 20030901

Title: Effects of 6-formylpterin as an internal source of hydrogen peroxide on cell death of human peripheral blood leukocytes.

Journal: Life sciences 20030530

Title: Singlet oxygen (1deltag) production by pterin derivatives in aqueous solutions.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20030301

Title: Syntheses of labeled vitamers of folic acid to be used as internal standards in stable isotope dilution assays.

Journal: Journal of agricultural and food chemistry 20020814

Title: Fluorescence of pterin, 6-formylpterin, 6-carboxypterin and folic acid in aqueous solution: pH effects.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020601

Title: Oxidative stress in vitiligo: photo-oxidation of pterins produces H(2)O(2) and pterin-6-carboxylic acid.

Journal: Biochemical and biophysical research communications 20020412

Title: 6-formylpterin intracellularly generates hydrogen peroxide and restores the impaired bactericidal activity of human neutrophils.

Journal: Biochemical and biophysical research communications 20011123

Title: 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation.

Journal: Free radical biology & medicine 20010201

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Tags:712-30-1 Molecular Formula|712-30-1 MDL|712-30-1 SMILES|712-30-1 2-Amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde