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71320-77-9,MFCD00865388
Catalog No.:AA00IC31

71320-77-9 | 4-Chloro-N-(2-morpholinoethyl)benzamide

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1mg
99%
in stock  
$12.00   $8.00
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5mg
99%
in stock  
$25.00   $18.00
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10mg
99%
in stock  
$33.00   $23.00
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50mg
98%(HPLC)
in stock  
$134.00   $94.00
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100mg
98%(HPLC)
in stock  
$245.00   $172.00
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250mg
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$255.00   $178.00
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1g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IC31
Chemical Name:
4-Chloro-N-(2-morpholinoethyl)benzamide
CAS Number:
71320-77-9
Molecular Formula:
C13H17ClN2O2
Molecular Weight:
268.7393
MDL Number:
MFCD00865388
SMILES:
O=C(c1ccc(cc1)Cl)NCCN1CCOCC1
Properties
Computed Properties
 
Complexity:
262  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
1.5  

Downstream Synthesis Route

[1]Kim,Dokyoung;Sambasivan,Sunderraman;Nam,Hyoseok;Ki,HeanKim;Jin,YongKim;Joo,Taiha;Lee,Kyung-Ha;Kim,Kyong-Tai;HanAhn,Kyo[ChemicalCommunications,2012,vol.48,#54,p.6833-6835]

[2]Ghanbarpour,Alireza;Hadizadeh,Farzin;Piri,Faride;Rashidi-Ranjbar,Parviz[PharmaceuticaActaHelvetiae,1997,vol.72,#2,p.119-122]

[3]Xing,Hui;Houston,SevanD.;Chen,Xuejie;Ghassabian,Sussan;Fahrenhorst-Jones,Tyler;Kuo,Andy;Murray,Cody-EllenP.;Conn,Kyna-Anne;Jaeschke,KaraN.;Jin,Da-Yun;Pasay,Cielo;Bernhardt,PaulV.;Burns,JedM.;Tsanaktsidis,John;Savage,G.Paul;Boyle,GlenM.;DeVoss,JamesJ.;McCarthy,James;Walter,GimmeH.;Burne,ThomasH.J.;Smith,MareeT.;Tie,Jian-Ke;Williams,CraigM.[Chemistry-AEuropeanJournal,2019,vol.25,#11,p.2729-2734]

[4]Donnier-Maréchal,Marion;Carato,Pascal;Larchanché,Paul-Emmanuel;Ravez,Séverine;Boulahjar,Rajaa;Barczyk,Amélie;Oxombre,Bénédicte;Vermersch,Patrick;Melnyk,Patricia[EuropeanJournalofMedicinalChemistry,2017,vol.138,p.964-978]

[5]CurrentPatentAssignee:ROCHEHOLDINGAG-US4210754,1980,A

[6]Iqbal,Naeem;Cho,EunJin[JournalofOrganicChemistry,2016,vol.81,#5,p.1905-1911]

[7]Huy,PeterH.;Mbouhom,Christelle[ChemicalScience,2019,vol.10,#31,p.7399-7406]

[1]Braddock,D.Christopher;Lickiss,PaulD.;Rowley,BenC.;Pugh,David;Purnomo,Teresa;Santhakumar,Gajan;Fussell,StevenJ.[OrganicLetters,2018,vol.20,#4,p.950-953]

[2]Liu,Tao;Zhang,Xue;Peng,Zejun;Zhao,Junfeng[GreenChemistry,2021,vol.23,#24,p.9916-9921]

[3]Allen,C.Liana;Chhatwal,A.Rosie;Williams,JonathanM.J.[ChemicalCommunications,2012,vol.48,#5,p.666-668]

[4]Li,Ningbo;Wang,Lingxiao;Zhang,Liting;Zhao,Wenjie;Qiao,Jie;Xu,Xinhua;Liang,Zhiwu[ChemCatChem,2018,vol.10,#16,p.3532-3538]

[5]CurrentPatentAssignee:H.LUNDBECKA/S-US2003/138376,2003,A1

[6]CurrentPatentAssignee:ROCHEHOLDINGAG-US4210754,1980,A

[7]Fairlamb,IanJ.S.;Grogan,Gideon;Lloyd,RichardC.;Petchey,MarkR.;Rowlinson,Benjamin[ACSCatalysis,2020,vol.10,#8,p.4659-4663]

71320-77-9   
Ro12-5637 

[1]Locationinpatent:schemeortableHanlon,StevenP.;Camattari,Andrea;Abad,Sandra;Glieder,Anton;Kittelmann,Matthias;Luetz,Stephan;Wirz,Beat;Winkler,Margit[ChemicalCommunications,2012,vol.48,#48,p.6001-6003]

[2]Hoskins;Shenfield;Murray;Gross[Xenobiotica,2001,vol.31,#7,p.387-397]

2038-03-1    104-88-1   
4-{2-(p-chlorobenzylidene)-amino-ethyl}-morpholine 
  71320-77-9 

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-US4210754,1980,A

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Title: Comparative validation of amisulpride determination in pharmaceuticals by several chromatographic, electrophoretic and spectrophotometric methods.

Journal: Analytica chimica acta 20070508

Title: Clinical and prognostic properties of standardized and functional aphasia assessments.

Journal: Journal of rehabilitation medicine 20070501

Title: Quantification of tricyclic antidepressants and monoamine oxidase inhibitors by high-performance liquid chromatography-tandem mass spectrometry in whole blood.

Journal: Journal of analytical toxicology 20070501

Title: Efficacy of moclobemide in a rat model of neurotoxicant-induced edema.

Journal: Canadian journal of physiology and pharmacology 20070501

Title: The effects of co-administration of 3,4-methylenedioxymethamphetamine ('ecstasy') or para-methoxyamphetamine and moclobemide at elevated ambient temperatures on striatal 5-HT, body temperature and behavior in rats.

Journal: Neuroscience 20070425

Title: The treatment of generalized anxiety disorder with pregabalin, an atypical anxiolytic.

Journal: Neuropsychiatric disease and treatment 20070401

Title: Moclobemide attenuates anoxia and glutamate-induced neuronal damage in vitro independently of interaction with glutamate receptor subtypes.

Journal: Brain research 20070323

Title: High-performance liquid chromatographic method for the determination of moclobemide and its two major metabolites in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20070312

Title: New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity.

Journal: Journal of medicinal chemistry 20070308

Title: Frontotemporal dementia: recommendations for therapeutic studies, designs, and approaches.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20070301

Title: Monoamine oxidase isoform-dependent tautomeric influence in the recognition of 3,5-diaryl pyrazole inhibitors.

Journal: Journal of medicinal chemistry 20070208

Title: Antidepressants for smoking cessation.

Journal: The Cochrane database of systematic reviews 20070124

Title: Enhancement of the anti-immobility action of antidepressants by a selective 5-HT7 receptor antagonist in the forced swimming test in mice.

Journal: European journal of pharmacology 20070119

Title: Urinary serotonin level is associated with serotonin syndrome after moclobemide, sertraline, and citalopram overdose.

Journal: Clinical toxicology (Philadelphia, Pa.) 20070101

Title: [Treatment of depressive disorder and comorbid personality pathology: combined therapy versus pharmacotherapy].

Journal: Tijdschrift voor psychiatrie 20070101

Title: Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology.

Journal: BMC neuroscience 20070101

Title: Chronologically overlapping occurrences of nicotine-induced anxiety- and depression-related behavioral symptoms: effects of anxiolytic and cannabinoid drugs.

Journal: BMC neuroscience 20070101

Title: Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.

Journal: PloS one 20070101

Title: [Pharmacologic correction of psycho-emotive disorders in the rehabilitation of patients after removal of brain tumors].

Journal: Voprosy onkologii 20070101

Title: Antidepressants in the treatment of fibromyalgia.

Journal: Neuropsychiatric disease and treatment 20061201

Title: [The serotonin syndrome. Fatal course of intoxication with citalopram and moclobemide].

Journal: Der Anaesthesist 20061101

Title: Immediate switching from moclobemide to duloxetine may induce serotonin syndrome.

Journal: The Journal of clinical psychiatry 20061101

Title: Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020

Title: Acute effects of moclobemide and deprenyl on 5-HT synthesis rates in the rat brain: An autoradiographic study.

Journal: Brain research bulletin 20061016

Title: A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder.

Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie 20061001

Title: Inhibition of N-methyl-D-aspartate receptor function appears to be one of the common actions for antidepressants.

Journal: Journal of psychopharmacology (Oxford, England) 20060901

Title: A comparison of the effects of citalopram and moclobemide on resting brain perfusion in social anxiety disorder.

Journal: Metabolic brain disease 20060901

Title: Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060801

Title: Moclobemide and cognitive behavioral therapy in the treatment of social phobia. A six-month controlled study and 24 months follow up.

Journal: Neuro endocrinology letters 20060801

Title: Differentiation of hippocampal stem cells into functional neurons: evolving our understanding of monoamine oxidase-A inhibition.

Journal: British journal of pharmacology 20060701

Title: Moclobemide upregulated Bcl-2 expression and induced neural stem cell differentiation into serotoninergic neuron via extracellular-regulated kinase pathway.

Journal: British journal of pharmacology 20060701

Title: A review of serotonin toxicity data: implications for the mechanisms of antidepressant drug action.

Journal: Biological psychiatry 20060601

Title: Antidepressants: general practitioners' opinions and clinical practice.

Journal: Acta psychiatrica Scandinavica 20060601

Title: Depression in Alzheimer's disease.

Journal: Expert review of neurotherapeutics 20060601

Title: [Trazodone for the treatment of behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease: a retrospective study focused on the aggression and negativism in caregiving situations].

Journal: No to shinkei = Brain and nerve 20060601

Title: Treatments in depression.

Journal: Dialogues in clinical neuroscience 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Transdermal selegiline: the new generation of monoamine oxidase inhibitors.

Journal: CNS spectrums 20060501

Title: An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.

Journal: British journal of clinical pharmacology 20060501

Title: A comparative study of fluoxetine, moclobemide, and tianeptine in the treatment of posttraumatic stress disorder following an earthquake.

Journal: European psychiatry : the journal of the Association of European Psychiatrists 20060401

Title: Phosducin-like protein levels in leukocytes of patients with major depression and in rat cortex: the effect of chronic treatment with antidepressants.

Journal: Psychiatry research 20060330

Title: Positron emission tomography quantification of [11C]-harmine binding to monoamine oxidase-A in the human brain.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20060301

Title: Treatment of depression with atypical features: a meta-analytic approach.

Journal: Psychiatry research 20060130

Title: A chronopharmacological diagnostic test and treatment for bipolar disorder and depression: nitric oxide release during sleep causes it to become depressogenic in a subset of patients.

Journal: Medical hypotheses 20060101

Title: A chronopharmacological preventive treatment for sleep-related migraine headaches and chronic morning headaches: Nitric oxide supersensitivity can cause sleep-related headaches in a subset of patients.

Journal: Medical hypotheses 20060101

Title: Use of psychotropic medications in treating mood disorders during lactation : practical recommendations.

Journal: CNS drugs 20060101

Title: Reappearance of catatonia. A case report.

Journal: Neuro endocrinology letters 20060101

Title: Biology and therapy of fibromyalgia. New therapies in fibromyalgia.

Journal: Arthritis research & therapy 20060101

Title: The AmpliChip CYP450 genotyping test: Integrating a new clinical tool.

Journal: Molecular diagnosis & therapy 20060101

Title: Pharmacotherapy of social anxiety disorder: what does the evidence tell us?

Journal: The Journal of clinical psychiatry 20060101

Title: Resistant social anxiety disorder response to Escitalopram.

Journal: Clinical practice and epidemiology in mental health : CP & EMH 20060101

Title: Antidepressants and their effect on sleep.

Journal: Human psychopharmacology 20051201

Title: Sleep and psychiatry.

Journal: Dialogues in clinical neuroscience 20051201

Title: Contribution of sleep research to the development of new antidepressants.

Journal: Dialogues in clinical neuroscience 20051201

Title: Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051102

Title: Newer antidepressants: evaluation of fatal toxicity index and interaction with alcohol based on Finnish postmortem data.

Journal: International journal of legal medicine 20051101

Title: Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment.

Journal: Psychopharmacology 20051101

Title: Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity.

Journal: British journal of anaesthesia 20051001

Title: Pharmacogenomics in depression and antidepressants.

Journal: Dialogues in clinical neuroscience 20050901

Title: The AGNP-TDM Expert Group Consensus Guidelines: focus on therapeutic monitoring of antidepressants.

Journal: Dialogues in clinical neuroscience 20050901

Title: Neuroendocrine predictors of the evolution of depression.

Journal: Dialogues in clinical neuroscience 20050901

Title: QTc abnormalities in deliberate self-poisoning with moclobemide.

Journal: Internal medicine journal 20050701

Title: Pseudohallucinations associated with moclobemide: a case report.

Journal: Pharmacopsychiatry 20050701

Title: Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors.

Journal: Journal of medicinal chemistry 20050630

Title: Effect of long-term administration of antidepressants on the lipid composition of brain plasma membranes.

Journal: General physiology and biophysics 20050601

Title: Effects of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') and para-methoxyamphetamine on striatal 5-HT when co-administered with moclobemide.

Journal: Brain research 20050411

Title: Effect of pharmacologically selective antidepressants on serotonin uptake in rat platelets.

Journal: General physiology and biophysics 20050301

Title: Onset of improvement and response to mirtazapine in depression: a multicenter naturalistic study of 4771 patients.

Journal: Neuropsychiatric disease and treatment 20050301

Title: A combination drug therapy improves cognition and reverses gene expression changes in a mouse model of Huntington's disease.

Journal: The European journal of neuroscience 20050201

Title: Opposite effects of antidepressants on unstimulated and stimulated salivary flow.

Journal: Archives of oral biology 20050101

Title: Long-term antidepressant treatment with moclobemide for aphasia in acute stroke patients: a randomised, double-blind, placebo-controlled study.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20050101

Title: Clinical pharmacokinetics of almotriptan, a serotonin 5-HT(1B/1D) receptor agonist for the treatment of migraine.

Journal: Clinical pharmacokinetics 20050101

Title: Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report.

Journal: Critical care (London, England) 20050101

Title: Social anxiety disorder : current treatment recommendations.

Journal: CNS drugs 20050101

Title: Orthostatic side effects of clomipramine and moclobemide during treatment for depression.

Journal: Nordic journal of psychiatry 20050101

Title: Comparison of the efficacy and safety of moclobemide and imipramine in the treatment of depression in Indian patients.

Journal: Indian journal of psychiatry 20050101

Title: Obsessive-compulsive disorder: An interface with possible psychotic features.

Journal: Indian journal of psychiatry 20050101

Title: Locomotor effects of imidazoline I2-site-specific ligands and monoamine oxidase inhibitors in rats with a unilateral 6-hydroxydopamine lesion of the nigrostriatal pathway.

Journal: British journal of pharmacology 20041201

Title: Effect of oral linezolid on the pressor response to intravenous tyramine.

Journal: British journal of clinical pharmacology 20041101

Title: Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.

Journal: Acta pharmacologica Sinica 20041101

Title: [Effect of madecassoside on depression behavior of mice and activities of MAO in different brain regions of rats].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20041101

Title: Differential regulation of variant glucocorticoid receptor mRNAs in the rat hippocampus by the antidepressant fluoxetine.

Journal: Brain research. Molecular brain research 20041022

Title: Antidepressants for smoking cessation.

Journal: The Cochrane database of systematic reviews 20041018

Title: SL25.1131 [3(S),3a(S)-3-methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a new, reversible, and mixed inhibitor of monoamine oxidase-A and monoamine oxidase-B: biochemical and behavioral profile.

Journal: The Journal of pharmacology and experimental therapeutics 20040901

Title: Sexual dysfunction associated with antidepressant drugs.

Journal: Expert opinion on drug safety 20040901

Title: [Biological treatment of depression in the elderly].

Journal: Psychologie & neuropsychiatrie du vieillissement 20040901

Title: Determination of moclobemide in human plasma by high-performance liquid chromatography with spectrophotometric detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040805

Title: Clinical applications of MAO-inhibitors.

Journal: Current medicinal chemistry 20040801

Title: A review of acute treatments for bipolar depression.

Journal: International clinical psychopharmacology 20040501

Title: Regulation of the human corticotropin-releasing-hormone gene promoter activity by antidepressant drugs in Neuro-2A and AtT-20 cells.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040401

Title: Trends in the development of new antidepressants. Is there a light at the end of the tunnel?

Journal: Current medicinal chemistry 20040401

Title: Effect of combined administration of 5-HT1A or 5-HT1B/1D receptor antagonists and antidepressants in the forced swimming test.

Journal: European journal of pharmacology 20040308

Title: The effects of moclobemide on autonomic and cognitive functions in healthy volunteers.

Journal: Pharmacopsychiatry 20040301

Title: Sex-dependent modulation of treatment response.

Journal: Dialogues in clinical neuroscience 20040301

Title: Death following acute poisoning by moclobemide.

Journal: Forensic science international 20040210

Title: Use of the elevated T-maze to study anxiety in mice.

Journal: Behavioural brain research 20040105

Title: Therapeutic applications of selective and non-selective inhibitors of monoamine oxidase A and B that do not cause significant tyramine potentiation.

Journal: Neurotoxicology 20040101

Title: Moclobemide and the risk of serotonin toxicity (or serotonin syndrome).

Journal: CNS drug reviews 20040101

Title: Three year naturalistic outcome study of panic disorder patients treated with paroxetine.

Journal: BMC psychiatry 20040101

Title: Antidepressants in chronic unpredictable mild stress (CUMS)-induced deficit of fighting behavior.

Journal: Polish journal of pharmacology 20040101

Title: [Neurobiology and pharmacotherapy of social phobia].

Journal: L'Encephale 20040101

Title: Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction.

Journal: Drug safety 20040101

Title: In vitro metabolism of zolmitriptan in rat cytochromes induced with beta-naphthoflavone and the interaction between six drugs and zolmitriptan.

Journal: Chemico-biological interactions 20031215

Title: cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20031201

Title: Effects of the antidepressant drug moclobemide on learning and memory in rats.

Journal: Methods and findings in experimental and clinical pharmacology 20031201

Title: Treatment of seasonal affective disorders.

Journal: Dialogues in clinical neuroscience 20031201

Title: Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptor.

Journal: Molecular psychiatry 20031101

Title: Moclobemide poisoning: toxicokinetics and occurrence of serotonin toxicity.

Journal: British journal of clinical pharmacology 20031001

Title: A high-performance liquid chromatography method with photodiode-array UV detection for therapeutic drug monitoring of the nontricyclic antidepressant drugs.

Journal: Therapeutic drug monitoring 20031001

Title: Cytoprotective effect is one of common action pathways for antidepressants.

Journal: Acta pharmacologica Sinica 20031001

Title: Possible involvement of opioid receptors in moclobemide-induced hypothermia in mice.

Journal: Pharmacological research 20030901

Title: Are gender differences important for the clinical effects of antidepressants?

Journal: The American journal of psychiatry 20030901

Title: Questions & answers. My friend swears by her antidepressant, moclobemide, which she gets from Canada because it is not available in the United States. She is content with the relief she is getting and happy about the absence of sexual side effects. What is moclobemide, and how can I decide whether it would be a good choice for me?

Journal: The Harvard mental health letter 20030901

Title: Analysis of eighteen antidepressants, four atypical antipsychotics and active metabolites in serum by liquid chromatography: a simple tool for therapeutic drug monitoring.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030825

Title: Pharmacological treatment of frontotemporal dementia: treatment response to the MAO-A inhibitor moclobemide.

Journal: International journal of geriatric psychiatry 20030701

Title: Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor.

Journal: Journal of neurochemistry 20030701

Title: Mapping the cerebral monoamine oxidase type A: positron emission tomography characterization of the reversible selective inhibitor [11C]befloxatone.

Journal: The Journal of pharmacology and experimental therapeutics 20030501

Title: Pre- and post-treatment with pirlindole and dehydropirlindole protects cultured brain cells against nitric oxide-induced death.

Journal: European journal of pharmacology 20030411

Title: Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B.

Journal: Journal of medicinal chemistry 20030313

Title: Death following ingestion of MDMA (ecstasy) and moclobemide.

Journal: Addiction (Abingdon, England) 20030301

Title: Fatal combination of moclobemide overdose and whisky.

Journal: The Netherlands journal of medicine 20030301

Title: Changes in personality pathology after pharmacotherapy and combined therapy for depressed patients.

Journal: Journal of personality disorders 20030201

Title: Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.

Journal: Archives of biochemistry and biophysics 20030101

Title: Treatment of depression with comorbid anxiety disorders: differential efficacy of paroxetine versus moclobemide.

Journal: International clinical psychopharmacology 20030101

Title: Antidepressants and driver impairment: empirical evidence from a standard on-the-road test.

Journal: The Journal of clinical psychiatry 20030101

Title: Moclobemide: therapeutic use and clinical studies.

Journal: CNS drug reviews 20030101

Title: Antidepressants for smoking cessation.

Journal: The Cochrane database of systematic reviews 20030101

Title: [Seasonal affective disorder].

Journal: Ryoikibetsu shokogun shirizu 20030101

Title: Efficacy of combined therapy and pharmacotherapy for depressed patients with or without personality disorders.

Journal: Harvard review of psychiatry 20030101

Title: Antidepressant-related erectile dysfunction: management via avoidance, switching antidepressants, antidotes, and adaptation.

Journal: The Journal of clinical psychiatry 20030101

Title: Antidepressants versus placebo for people with bulimia nervosa.

Journal: The Cochrane database of systematic reviews 20030101

Title: A preliminary open-label study of moclobemide treatment of pain disorder.

Journal: Psychopharmacology bulletin 20030101

Title: Efficacy of citalopram and moclobemide in patients with social phobia: some preliminary findings.

Journal: Human psychopharmacology 20021201

Title: Human models as tools in the development of psychotropic drugs.

Journal: Dialogues in clinical neuroscience 20021201

Title: Simulating the anhedonia symptom of depression in animals.

Journal: Dialogues in clinical neuroscience 20021201

Title: LC determination of moclobemide and three metabolites in plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20021107

Title: Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits.

Journal: Neuropharmacology 20021101

Title: The lack of a placebo effect in a trial of fluoxetine in the treatment of fibromyalgia.

Journal: The American journal of medicine 20021101

Title: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders.

Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20021001

Title: Moclobemide discontinuation syndrome predominantly presenting with influenza-like symptoms.

Journal: Journal of psychopharmacology (Oxford, England) 20020901

Title: Psychopharmacology of anxiety disorders.

Journal: Dialogues in clinical neuroscience 20020901

Title: Nonpharmacological treatments for anxiety disorders.

Journal: Dialogues in clinical neuroscience 20020901

Title: Moclobemide is effective and well tolerated in the long-term pharmacotherapy of social anxiety disorder with or without comorbid anxiety disorder.

Journal: International clinical psychopharmacology 20020701

Title: Moclobemide response in depressed patients: association study with a functional polymorphism in the monoamine oxidase A promoter.

Journal: Pharmacopsychiatry 20020701

Title: [Serotonin syndrome--several cases of this often overlooked diagnosis].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020630

Title: Interactive model of therapeutic response in panic disorder: moclobemide, a case in point.

Journal: Journal of clinical psychopharmacology 20020601

Title: Treatment of depression associated with the menstrual cycle: premenstrual dysphoria, postpartum depression, and the perimenopause.

Journal: Dialogues in clinical neuroscience 20020601

Title: Differential effects of chronic antidepressant treatments on micro- and delta-opioid receptors in rat brain.

Journal: European journal of pharmacology 20020517

Title: [Serotonin syndrome. Several cases of this often overlooked diagnosis].

Journal: Lakartidningen 20020502

Title: How well do antidepressants work in older people? A systematic review of Number Needed to Treat.

Journal: Journal of affective disorders 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19.

Journal: British journal of clinical pharmacology 20020401

Title: Treatment of comorbid opiate addiction and attention-deficit hyperactivity disorder (residual type) with moclobemide: a case report.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20020401

Title: Frovatriptan: a review of drug-drug interactions.

Journal: Headache 20020401

Title: Characterization of the discriminable stimulus produced by 2-BFI: effects of imidazoline I(2)-site ligands, MAOIs, beta-carbolines, agmatine and ibogaine.

Journal: British journal of pharmacology 20020301

Title: Effect of TV3326, a novel monoamine-oxidase cholinesterase inhibitor, in rat models of anxiety and depression.

Journal: Psychopharmacology 20020301

Title: Antidepressant side effects in depression patients treated in a naturalistic setting: a study of bupropion, moclobemide, paroxetine, sertraline, and venlafaxine.

Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie 20020301

Title: Serotonin syndrome due to an overdose of moclobemide?

Journal: CJEM 20020301

Title: The clinical pharmacology of depressive states.

Journal: Dialogues in clinical neuroscience 20020301

Title: Pirlindole and dehydropirlindole protect rat cultured neuronal cells against oxidative stress-induced cell death through a mechanism unrelated to MAO-A inhibition.

Journal: British journal of pharmacology 20020201

Title: Pharmacotherapy of social anxiety disorder.

Journal: Biological psychiatry 20020101

Title: The influence on treatment gain of comorbid avoidant personality disorder in patients with social phobia.

Journal: The Journal of nervous and mental disease 20020101

Title: Antidepressants for smoking cessation.

Journal: The Cochrane database of systematic reviews 20020101

Title: Consultation-liaison psychiatrists' use of antidepressants in the physically ill.

Journal: Psychosomatics 20020101

Title: [Changes in the EEG rhythms in endogenous depressive disorders and the effect of pharmacotherapy].

Journal: Fiziologiia cheloveka 20020101

Title: Clinical pharmacokinetics of intranasal sumatriptan.

Journal: Clinical pharmacokinetics 20020101

Title: Moclobemide: evolution, pharmacodynamic, and pharmacokinetic properties.

Journal: CNS drug reviews 20020101

Title: [Prognostic value of pharmaco-EEG in depression treated with moclobemide].

Journal: Psychiatria polska 20020101

Title: Moclobemide in the treatment of hot flashes in postmenopausal women.

Journal: Advances in therapy 20020101

Title: The antinociceptive effect of moclobemide on the vocalization threshold to paw pressure in a rat model of unilateral mononeuropathy.

Journal: Pharmacological research 20011201

Title: Effect of nonnicotine pharmacotherapy on smoking behavior.

Journal: Pharmacotherapy 20011201

Title: Effects of harmine on dopamine output and metabolism in rat striatum: role of monoamine oxidase-A inhibition.

Journal: Psychopharmacology 20011201

Title: Chronic antidepressant treatments decrease pro-opiomelanocortin mRNA expression in the pituitary gland: effects of acute stress and 5-HT(1A) receptor activation.

Journal: Journal of neuroendocrinology 20011001

Title: Antidepressants in social anxiety disorder.

Journal: Arquivos de neuro-psiquiatria 20010901

Title: Moclobemide vs. imipramine in bipolar depression: a multicentre double-blind clinical trial.

Journal: Acta psychiatrica Scandinavica 20010801

Title: [Reversible inhibitor of MAO-A(RIMA)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010801

Title: Review of pharmacokinetic and pharmacodynamic interaction studies with citalopram.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010801

Title: Characterization of moclobemide N-oxidation in human liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20010701

Title: Effects of moclobemide on sexual performance and nocturnal erections in psychogenic erectile dysfunction.

Journal: Psychopharmacology 20010601

Title: Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.

Journal: European journal of pharmacology 20010518

Title: Combining psychotherapy and antidepressants in the treatment of depression.

Journal: Journal of affective disorders 20010501

Title: Cardiovascular sympathomimetic amine interactions in rats treated with monoamine oxidase inhibitors and the novel oxazolidinone antibiotic linezolid.

Journal: Journal of cardiovascular pharmacology 20010501

Title: Linezolid, a novel oxazolidinone antibiotic: assessment of monoamine oxidase inhibition using pressor response to oral tyramine.

Journal: Journal of clinical pharmacology 20010501

Title: Effect of MAO-A inhibition on the pharmacokinetics of almotriptan, an antimigraine agent in humans.

Journal: British journal of clinical pharmacology 20010501

Title: High-performance liquid chromatography-electrospray ionization mass spectrometry method for the measurement of moclobemide and two metabolites in plasma.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010425

Title: Combined treatment with corticosteroids and moclobemide favors normalization of hypothalamo-pituitary-adrenal axis dysregulation in relapsing-remitting multiple sclerosis: a randomized, double blind trial.

Journal: The Journal of clinical endocrinology and metabolism 20010401

Title: Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19.

Journal: Clinical pharmacology and therapeutics 20010401

Title: A fatal case of serotonin syndrome after combined moclobemide-citalopram intoxication.

Journal: Journal of analytical toxicology 20010301

Title: Moclobemide in pregnancy.

Journal: Pharmacopsychiatry 20010301

Title: Musical hallucinations associated with abruptly developed bilateral loss of hearing.

Journal: Acta psychiatrica Scandinavica 20010201

Title: Current trends in the development of new antidepressants.

Journal: Current medicinal chemistry 20010201

Title: Screening for detection of new antidepressants, neuroleptics, hypnotics, and their metabolites in urine by GC-MS developed using rat liver microsomes.

Journal: Therapeutic drug monitoring 20010201

Title: Acute effect of different antidepressants on glycemia in diabetic and non-diabetic rats.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010101

Title: Efficacy and tolerability of moclobemide in bulimia nervosa: a placebo-controlled trial.

Journal: International clinical psychopharmacology 20010101

Title: Treatment of social phobia with antidepressants.

Journal: The Journal of clinical psychiatry 20010101

Title: Incidence of sexual dysfunction associated with antidepressant agents: a prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction.

Journal: The Journal of clinical psychiatry 20010101

Title: A randomized controlled trial comparing moclobemide and moclobemide plus interpersonal psychotherapy in the treatment of dysthymic disorder.

Journal: The Journal of psychotherapy practice and research 20010101

Title: Effects of the monoamine oxidase A inhibitor moclobemide on hippocampal plasticity in GR-impaired transgenic mice.

Journal: Journal of psychiatric research 20010101

Title: Clinically significant drug interactions with agents specific for migraine attacks.

Journal: CNS drugs 20010101

Title: Determination of moclobemide, paroxetine, and fluvoxamine in tablets by HPLC.

Journal: Acta poloniae pharmaceutica 20010101

Title: Meta-analytical studies on new antidepressants.

Journal: British medical bulletin 20010101

Title: A fatal case of moclobemide-citalopram intoxication.

Journal: Journal of analytical toxicology 20010101

Title: Reversal of stress-induced memory changes by moclobemide: the role of neurotransmitters.

Journal: Polish journal of pharmacology 20010101

Title: Antidepressant-induced sexual dysfunction during treatment with moclobemide, paroxetine, sertraline, and venlafaxine.

Journal: The Journal of clinical psychiatry 20000401

Title: Switching to moclobemide to reverse fluoxetine-induced sexual dysfunction in patients with depression.

Journal: Journal of psychiatry & neuroscience : JPN 19990101

Title: Serotonin syndrome--clomipramine too soon after moclobemide?

Journal: International clinical psychopharmacology 19971101

Title: Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group.

Journal: International clinical psychopharmacology 19970701

Title: Moclobemide. An update of its pharmacological properties and therapeutic use.

Journal: Drugs 19960901

Title: [Sexual dysfunction secondary to SSRIs. A comparative analysis in 308 patients].

Journal: Actas luso-espanolas de neurologia, psiquiatria y ciencias afines 19960101

Title: Hypertension with moclobemide.

Journal: Lancet (London, England) 19951014

Title: Clozapine-induced hypotension treated with moclobemide and Bovril.

Journal: The British journal of psychiatry : the journal of mental science 19950901

Title: Possible serotonin syndrome with moclobemide and pethidine.

Journal: The Medical journal of Australia 19950515

Title: Moclobemide versus fluoxetine for a major depressive episode.

Journal: Psychopharmacology 19950301

Title: Serotonin syndrome caused by a moclobemide-clomipramine interaction.

Journal: BMJ (Clinical research ed.) 19930123

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Tags:71320-77-9 Molecular Formula|71320-77-9 MDL|71320-77-9 SMILES|71320-77-9 4-Chloro-N-(2-morpholinoethyl)benzamide