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716-11-0,MFCD00023908
Catalog No.:AA00FG7O

716-11-0 | 1-(4-Methylquinazolin-2-yl)guanidine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
>97%
1 week  
$299.00   $209.00
- +
5mg
>97%
1 week  
$319.00   $223.00
- +
10mg
>97%
1 week  
$358.00   $250.00
- +
500mg
>97%
1 week  
$589.00   $412.00
- +
1g
>97%
1 week  
$813.00   $569.00
- +
  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FG7O
Chemical Name:
1-(4-Methylquinazolin-2-yl)guanidine
CAS Number:
716-11-0
Molecular Formula:
C10H11N5
Molecular Weight:
201.2278
MDL Number:
MFCD00023908
SMILES:
NC(=N)Nc1nc2ccccc2c(n1)C
NSC Number:
403387
Properties
Computed Properties
 
Complexity:
248  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
0.8  

Literature

Title: Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline.

Journal: The Journal of biological chemistry 20121019

Title: Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride.

Journal: The Journal of biological chemistry 20111209

Title: Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels.

Journal: The Journal of biological chemistry 20110715

Title: Acid-sensing ion channel 1a is involved in retinal ganglion cell death induced by hypoxia.

Journal: Molecular vision 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: A nonproton ligand sensor in the acid-sensing ion channel.

Journal: Neuron 20101006

Title: ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain.

Journal: Molecular pain 20100101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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