Name: Name:2-Chloro-5-(difluoromethyl)pyridine
Brand: AABLOCKS
SKU: AA00FV30
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00FV30

Chemical Name: 2-Chloro-5-(difluoromethyl)pyridine

CAS Number: 71701-99-0

Molecular Formula: C6H4ClF2N

Molecular Weight: 163.5525

MDL Number: MFCD16140199

SMILES: Clc1ccc(cn1)C(F)F

Properties

Complexity: 110

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 10

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.4

Downstream Synthesis Route

23100-12-1

71701-99-0

[1]Liu,Ping;Lin,LinusS.;Hamill,TerenceG.;Jewell,JamesP.;LanzaJr.,ThomasJ.;Gibson,RaymondE.;Krause,StephenM.;Ryan,Christine;Eng,Waisi;Sanabria,Sandra;Tong,Xinchun;Wang,Junying;Levorse,DorothyA.;Owens,KarenA.;Fong,TungM.;Shen,Chun-Pyn;Lao,Julie;Kumar,Sanjeev;Yin,Wenji;Payack,JosephF.;Springfield,ShawnA.;Hargreaves,Richard;Burns,H.Donald;Goulet,MarkT.;Hagmann,WilliamK.[JournalofMedicinalChemistry,2007,vol.50,#15,p.3427-3430]

[2]CurrentPatentAssignee:MERCK&COINC-WO2005/9479,2005,A1Locationinpatent:Page/Pagecolumn41

[3]CurrentPatentAssignee:MERCK&COINC-WO2010/146083,2010,A1Locationinpatent:Page/Pagecolumn41-42

71701-99-0

594-61-6

883858-12-6

[1]Liu,Ping;Lin,LinusS.;Hamill,TerenceG.;Jewell,JamesP.;LanzaJr.,ThomasJ.;Gibson,RaymondE.;Krause,StephenM.;Ryan,Christine;Eng,Waisi;Sanabria,Sandra;Tong,Xinchun;Wang,Junying;Levorse,DorothyA.;Owens,KarenA.;Fong,TungM.;Shen,Chun-Pyn;Lao,Julie;Kumar,Sanjeev;Yin,Wenji;Payack,JosephF.;Springfield,ShawnA.;Hargreaves,Richard;Burns,H.Donald;Goulet,MarkT.;Hagmann,WilliamK.[JournalofMedicinalChemistry,2007,vol.50,#15,p.3427-3430]

71701-99-0

947371-16-6

[1]Liu,Ping;Lin,LinusS.;Hamill,TerenceG.;Jewell,JamesP.;LanzaJr.,ThomasJ.;Gibson,RaymondE.;Krause,StephenM.;Ryan,Christine;Eng,Waisi;Sanabria,Sandra;Tong,Xinchun;Wang,Junying;Levorse,DorothyA.;Owens,KarenA.;Fong,TungM.;Shen,Chun-Pyn;Lao,Julie;Kumar,Sanjeev;Yin,Wenji;Payack,JosephF.;Springfield,ShawnA.;Hargreaves,Richard;Burns,H.Donald;Goulet,MarkT.;Hagmann,WilliamK.[JournalofMedicinalChemistry,2007,vol.50,#15,p.3427-3430]

71701-99-0

947371-38-2

[1]Liu,Ping;Lin,LinusS.;Hamill,TerenceG.;Jewell,JamesP.;LanzaJr.,ThomasJ.;Gibson,RaymondE.;Krause,StephenM.;Ryan,Christine;Eng,Waisi;Sanabria,Sandra;Tong,Xinchun;Wang,Junying;Levorse,DorothyA.;Owens,KarenA.;Fong,TungM.;Shen,Chun-Pyn;Lao,Julie;Kumar,Sanjeev;Yin,Wenji;Payack,JosephF.;Springfield,ShawnA.;Hargreaves,Richard;Burns,H.Donald;Goulet,MarkT.;Hagmann,WilliamK.[JournalofMedicinalChemistry,2007,vol.50,#15,p.3427-3430]

71701-99-0

947371-39-3

[1]Liu,Ping;Lin,LinusS.;Hamill,TerenceG.;Jewell,JamesP.;LanzaJr.,ThomasJ.;Gibson,RaymondE.;Krause,StephenM.;Ryan,Christine;Eng,Waisi;Sanabria,Sandra;Tong,Xinchun;Wang,Junying;Levorse,DorothyA.;Owens,KarenA.;Fong,TungM.;Shen,Chun-Pyn;Lao,Julie;Kumar,Sanjeev;Yin,Wenji;Payack,JosephF.;Springfield,ShawnA.;Hargreaves,Richard;Burns,H.Donald;Goulet,MarkT.;Hagmann,WilliamK.[JournalofMedicinalChemistry,2007,vol.50,#15,p.3427-3430]

71701-99-0 | 2-Chloro-5-(difluoromethyl)pyridine