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71720-56-4,MFCD00150770
Catalog No.:AA003QI9

71720-56-4 | Fenoprofen calcium salt dihydrate

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1mg
98%
in stock  
$6.00   $4.00
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250mg
98%
in stock  
$9.00   $7.00
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1g
98%
in stock  
$14.00   $10.00
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25g
>98.0%(T)
in stock  
$198.00   $139.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003QI9
Chemical Name:
Fenoprofen calcium salt dihydrate
CAS Number:
71720-56-4
Molecular Formula:
C15H15CaO4+
Molecular Weight:
299.3552
MDL Number:
MFCD00150770
SMILES:
[O-]C(=O)C(c1cccc(c1)Oc1ccccc1)C.O.[Ca+2]
Properties
Properties
 
Form:
Solid  
MP:
>94ºC (dec.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
265  
Covalently-Bonded Unit Count:
5  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
2  

Literature

Title: Immediate release three-layered chewing gum tablets of fenoprofen calcium: preparation, optimization and bioavailability studies in healthy human volunteers.

Journal: Drug development and industrial pharmacy 20120501

Title: Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery.

Journal: The Cochrane database of systematic reviews 20120215

Title: Anti-nociceptive activity and toxicity evaluation of Cu(II)-fenoprofenate complexes in mice.

Journal: European journal of pharmacology 20120130

Title: Potential of synchrotron X-ray powder diffractometry for detection and quantification of small amounts of crystalline drug substances in pharmaceutical tablets.

Journal: Journal of pharmaceutical and biomedical analysis 20110910

Title: A highly sensitive method for enantioseparation of fenoprofen and amino acid derivatives by capillary electrophoresis with on-line sample preconcentration.

Journal: Journal of chromatography. A 20110401

Title: Single dose oral fenoprofen for acute postoperative pain in adults.

Journal: The Cochrane database of systematic reviews 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Electrokinetic supercharging focusing in capillary zone electrophoresis of weakly ionizable analytes in environmental and biological samples.

Journal: Electrophoresis 20100901

Title: Rapid simultaneous determination of four non-steroidal anti-inflammatory drugs by means of derivative nonlinear variable-angle synchronous fluorescence spectrometry.

Journal: Applied spectroscopy 20100801

Title: Chemoenzymatic and microbial dynamic kinetic resolutions.

Journal: Chirality 20090401

Title: Synthesis of dehydroabietic acid-modified chitosan and its drug release behavior.

Journal: Carbohydrate research 20090105

Title: Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20080101

Title: Stereoselective disposition of fenoprofen in plasma and synovial fluid of patients with rheumatoid arthritis.

Journal: Chirality 20070505

Title: Fenoprofen and ketoprofen amides as potential antitumor agents.

Journal: Chemical biology & drug design 20070301

Title: Synthesis and in vitro antitumor effect of diclofenac and fenoprofen thiolated and nonthiolated polyaspartamide-drug conjugates.

Journal: European journal of medicinal chemistry 20070101

Title: Pharmacodynamics, chiral pharmacokinetics, and pharmacokinetic-pharmacodynamic modeling of fenoprofen in patients with diabetes mellitus.

Journal: Journal of clinical pharmacology 20061101

Title: Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8).

Journal: Pharmaceutical research 20060601

Title: Optimization of gas chromatographic method for the enantioseparation of arylpropionic non-steroidal anti-inflammatory drug methyl esters.

Journal: Journal of pharmaceutical and biomedical analysis 20050915

Title: Pharmaceutical liquid crystals: the relevance of partially ordered systems.

Journal: Journal of pharmaceutical sciences 20050901

Title: Synthesis of fenoprofen and gemfibrozil styrene-maleic acid copolymer conjugates.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20050601

Title: Using terahertz pulsed spectroscopy to quantify pharmaceutical polymorphism and crystallinity.

Journal: Journal of pharmaceutical sciences 20050401

Title: Influence of rheumatoid arthritis in the enantioselective disposition of fenoprofen.

Journal: Chirality 20041101

Title: Enantioselective kinetic disposition of fenoprofen in rats with experimental diabetes or adjuvant-induced arthritis.

Journal: Pharmacology 20041001

Title: Application of capillary electrophoresis with different sample stacking strategies for the determination of a group of nonsteroidal anti-inflammatory drugs in the low microg x L(-1) concentration range.

Journal: Electrophoresis 20040201

Title: Enhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis.

Journal: Electrophoresis 20030101

Title: Physical stability and solubility of the thermotropic mesophase of fenoprofen calcium as pure drug and in a tablet formulation.

Journal: International journal of pharmaceutics 20021024

Title: Macromolecular prodrugs: X. Kinetics of fenoprofen release from PHEA-fenoprofen conjugate.

Journal: International journal of pharmaceutics 20020725

Title: Chiral inversion of (R)-(-)-fenoprofen in guinea-pigs pretreated with clofibrate.

Journal: Veterinary research communications 20020601

Title: Macromolecular prodrugs. IX. Synthesis of polymer-fenoprofen conjugates.

Journal: International journal of pharmaceutics 20011009

Title: Enantioselective inhibition of the binding of rac-profens to human serum albumin induced by lithocholate.

Journal: Chirality 20010701

Title: Dehydration, hydration behavior, and structural analysis of fenoprofen calcium.

Journal: Journal of pharmaceutical sciences 20010701

Title: [Study on the release mechanism of fenoprofen calcium from hydrophillic sustained-release matrix].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20010101

Title: Topical non-steroidal drugs are systemically absorbed and may cause renal disease.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19990101

Title: Multi-site binding of fenoprofen to human serum albumin studied by a combined technique of microdialysis with high performance liquid chromatography.

Journal: Biomedical chromatography : BMC 19980101

Title: Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.

Journal: Journal of pharmacokinetics and biopharmaceutics 19970201

Title: Interaction of valproic acid with nonsteroidal antiinflammatory drugs mefenamic acid and fenoprofen in normal and uremic sera: lack of interaction in uremic sera due to the presence of endogenous factors.

Journal: Therapeutic drug monitoring 19961201

Title: Nonsteroidal anti-inflammatory drugs and coma: a case report of fenoprofen overdose.

Journal: Annals of emergency medicine 19900401

Title: Fenoprofen-induced immune hemolysis. Difficulties in diagnosis and complications in compatibility testing.

Journal: American journal of clinical pathology 19880301

Title: Fenoprofen-induced membranous glomerulonephritis.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19880101

Title: Progression of minimal-change glomerulopathy to focal glomerulosclerosis in a patient with fenoprofen nephropathy.

Journal: American journal of nephrology 19860101

Title: Efficacy of fenoprofen in the treatment of primary dysmenorrhea.

Journal: The Journal of reproductive medicine 19851201

Title: Acute tubular necrosis and minimal-change glomerulopathy associated with fenoprofen therapy.

Journal: Indiana medicine : the journal of the Indiana State Medical Association 19841201

Title: Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.

Journal: The American journal of medicine 19840601

Title: [Reversible acute renal failure caused by brufen].

Journal: Klinicheskaia meditsina 19840501

Title: Pure red cell aplasia associated with fenoprofen.

Journal: The American journal of the medical sciences 19840101

Title: [Acute renal insufficiency and recurrent thrombopenia caused by crossed intolerance to ibuprofen and fenoprofen].

Journal: Presse medicale (Paris, France : 1983) 19831126

Title: T and B lymphocyte subsets in fenoprofen nephropathy.

Journal: The American journal of medicine 19830701

Title: [Acute renal failure with nephrotic syndrome caused by fenoprofen. Reflections apropos of a case and review of the literature].

Journal: Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 19830322

Title: Acute renal failure possibly associated with fenoprofen therapy.

Journal: Arthritis and rheumatism 19830201

Title: Drug-induced acute interstitial nephritis with granulomas.

Journal: Human pathology 19830101

Title: [Acute renal failure and nephrotic syndrome after ingestion of fenoprofen].

Journal: La Nouvelle presse medicale 19820619

Title: Aplastic anaemia associated with fenoprofen.

Journal: British medical journal (Clinical research ed.) 19820501

Title: Fenoprofen nephropathy: lipoid nephrosis and interstitial nephritis. A possible T-lymphocyte disorder.

Journal: The American journal of medicine 19820101

Title: [Reversible acute renal failure and nephrotic syndrome induced by fenoprofene ].

Journal: Nephrologie 19820101

Title: Fenoprofen-induced acute interstitial nephritis presenting with nephrotic syndrome.

Journal: Minnesota medicine 19810501

Title: Renal failure associated with fenoprofen.

Journal: Mayo Clinic proceedings 19800201

Title: Reversible rapidly progressive renal failure with nephrotic syndrome due to fenoprofen calcium.

Journal: Annals of internal medicine 19800101

Title: Reversible renal failure and nephrotic syndrome associated with nonsteroidal anti-inflammatory drugs.

Journal: The New England journal of medicine 19791206

Title: Renal papillary necrosis and pyelonephritis accompanying fenoprofen therapy.

Journal: JAMA 19791026

Title: Agranulocytosis associated with fenoprofen.

Journal: JAMA 19790622

Title: Comparative assessment of fenoprofen and paracetamol given in combination for pain after surgery.

Journal: British journal of anaesthesia 19780901

Title: Comparison of graphical and computerized methods for calculating binding parameters for two strongly bound drugs to human serum albumin.

Journal: Journal of pharmaceutical sciences 19760801

Title: Takashima-Hirano M, et al. General method for the (11)C-labeling of 2-arylpropionic acids and their esters: construction of a PET tracer library for a study of biological events involved in COXs expression. Chemistry. 2010 Apr 12;16(14):4250-8.

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