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71751-77-4,MFCD08702703
Catalog No.:AA0062DQ

71751-77-4 | Meleagrin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$219.00   $153.00
- +
5mg
≥98%
in stock  
$816.00   $571.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0062DQ
Chemical Name:
Meleagrin
CAS Number:
71751-77-4
Molecular Formula:
C23H23N5O4
Molecular Weight:
433.4598
MDL Number:
MFCD08702703
SMILES:
CON1c2ccccc2C2(C31NC(=O)C(=Cc1cnc[nH]1)N3C(=O)C(=C2)O)C(C=C)(C)C
Properties
Properties
 
Form:
Solid  
MP:
>165ºC  
Storage:
-20 ℃;Inert atmosphere;Light sensitive;  

Computed Properties
 
Complexity:
929  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
3  

Literature

Title: A branched biosynthetic pathway is involved in production of roquefortine and related compounds in Penicillium chrysogenum.

Journal: PloS one 20130101

Title: Roquefortine/oxaline biosynthesis pathway metabolites in Penicillium ser. Corymbifera: in planta production and implications for competitive fitness.

Journal: Journal of chemical ecology 20051001

Title: [The biosynthesis of low-molecular-weight nitrogen-containing secondary metabolite-alkaloids by the resident strains of Penicillium chrysogenum and Penicillium expansum isolated on the board of the Mir space station ].

Journal: Mikrobiologiia 20020101

Title: Newmister SA, et al. Unveiling sequential late-stage methyltransferase reactions in the meleagrin/oxaline biosyntheticpathway. Org Biomol Chem. 2018 Sep 11;16(35):6450-6459.

Title: Zheng CJ, et al. Meleagrin, a new FabI inhibitor from Penicillium chryosogenum with at least one additional mode of action. PLoS One. 2013 Nov 28;8(11):e78922.

Title: Mady MS, et al. The indole alkaloid meleagrin, from the olive tree endophytic fungus Penicillium chrysogenum, as a novel lead for the control of c-Met-dependent breast cancer proliferation, migration and invasion. Bioorg Med Chem. 2016 Jan 15;24(2):113-22.

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