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72-43-5,MFCD00000803
Catalog No.:AA005TGL

72-43-5 | Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-

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25g
>95.0%(GC)
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005TGL
Chemical Name:
Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy-
CAS Number:
72-43-5
Molecular Formula:
C16H15Cl3O2
Molecular Weight:
345.6481
MDL Number:
MFCD00000803
SMILES:
COc1ccc(cc1)C(C(Cl)(Cl)Cl)c1ccc(cc1)OC
NSC Number:
8945
Properties
Properties
 
BP:
346.0°C  
Form:
Solid  
MP:
86-88℃ (lit.)  

Computed Properties
 
Complexity:
279  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
5.1  

Literature

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Title: Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity.

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Title: Differentiating true androgen receptor inhibition from cytotoxicity-mediated reduction of reporter-gene transactivation in-vitro.

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Title: Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells.

Journal: Carcinogenesis 20170301

Title: Incorporation of a metabolizing system in biodetection assays for endocrine active substances.

Journal: ALTEX 20170101

Title: Methoxychlor and Vinclozolin Induce Rapid Changes in Intercellular and Intracellular Signaling in Liver Progenitor Cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160901

Title: In utero methoxychlor exposure increases rat fetal Leydig cell number but inhibits its function.

Journal: Toxicology 20160831

Title: Transcriptional networks associated with the immune system are disrupted by organochlorine pesticides in largemouth bass (Micropterus salmoides) ovary.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20160801

Title: Regulation of arcuate genes by developmental exposures to endocrine-disrupting compounds in female rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20160701

Title: Novel full logistic model for estimation of the estrogenic activity of chemical mixtures.

Journal: Toxicology 20160601

Title: Development and pre-validation of an in vitro transactivation assay for detection of (anti)androgenic potential compounds using 22Rv1/MMTV cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20160401

Title: Methoxychlor and fenvalerate induce neuronal death by reducing GluR2 expression.

Journal: The Journal of toxicological sciences 20160401

Title: Endocrine-Disrupting Effects of Pesticides through Interference with Human Glucocorticoid Receptor.

Journal: Environmental science & technology 20160105

Title: Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for improved detection of estrogenic/antiestrogenic chemicals.

Journal: Environmental toxicology and chemistry 20160101

Title: Zebrafish biosensor for toxicant induced muscle hyperactivity.

Journal: Scientific reports 20160101

Title: Improved assays for xenosensor activation based on reverse transfection.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20151001

Title: Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.

Journal: Toxicology and applied pharmacology 20150401

Title: Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150201

Title: Methoxychlor and its metabolite HPTE inhibit cAMP production and expression of estrogen receptors α and β in the rat granulosa cell in vitro.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20150101

Title: Interactions of endosulfan and methoxychlor involving CYP3A4 and CYP2B6 in human HepaRG cells.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20140801

Title: Effects of estradiol and methoxychlor on Leydig cell regeneration in the adult rat testis.

Journal: International journal of molecular sciences 20140501

Title: Endocrine disrupting effects of dichlorodiphenyltrichloroethane analogues on gonadotropin hormones in pituitary gonadotrope cells.

Journal: Environmental toxicology and pharmacology 20140501

Title: Methoxychlor and triclosan stimulates ovarian cancer growth by regulating cell cycle- and apoptosis-related genes via an estrogen receptor-dependent pathway.

Journal: Environmental toxicology and pharmacology 20140501

Title: Environmental (anti-)androgenic chemicals affect germinal vesicle breakdown (GVBD) of Xenopus laevis oocytes in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140401

Title: Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on human and rat 17α-hydroxylase/17,20-lyase activity.

Journal: Toxicology letters 20140321

Title: Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.

Journal: Scientific reports 20140101

Title: Perinatal exposure to low-dose methoxychlor impairs testicular development in C57BL/6 mice.

Journal: PloS one 20140101

Title: Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline.

Journal: PloS one 20140101

Title: Toxicity assessment and vitellogenin expression in zebrafish (Danio rerio) embryos and larvae acutely exposed to bisphenol A, endosulfan, heptachlor, methoxychlor and tetrabromobisphenol A.

Journal: Journal of applied toxicology : JAT 20130701

Title: Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells.

Journal: Archives of toxicology 20130601

Title: Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 11β-hydroxysteroid dehydrogenase activities in vitro.

Journal: Toxicology letters 20130327

Title: Targeted genome-wide methylation and gene expression analyses reveal signaling pathways involved in ovarian dysfunction after developmental EDC exposure in rats.

Journal: Biology of reproduction 20130201

Title: Immunotoxicity in mice induced by short-term exposure to methoxychlor, parathion, or piperonyl butoxide.

Journal: Journal of immunotoxicology 20130101

Title: A computational model to predict rat ovarian steroid secretion from in vitro experiments with endocrine disruptors.

Journal: PloS one 20130101

Title: Optimization and validation of organochlorine compounds in adipose tissue by SPE-gas chromatography.

Journal: Biomedical chromatography : BMC 20121201

Title: Methoxychlor induces atresia by altering Bcl2 factors and inducing caspase activity in mouse ovarian antral follicles in vitro.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20121201

Title: Distinct mechanisms of endocrine disruption of DDT-related pesticides toward estrogen receptor α and estrogen-related receptor γ.

Journal: Environmental toxicology and chemistry 20121101

Title: Effect of methoxychlor on Ca(2+) movement and viability in MDCK renal tubular cells.

Journal: Basic & clinical pharmacology & toxicology 20121001

Title: Parts per trillion level determination of endocrine-disrupting chlorinated compounds in river water and wastewater effluent by stir-bar-sorptive extraction followed by gas chromatography-triple quadrupole mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20121001

Title: Role of regulatory T cells in the induction of atopic dermatitis by immunosuppressive chemicals.

Journal: Toxicology letters 20120918

Title: Brain organochlorines and Lewy pathology: the Honolulu-Asia Aging Study.

Journal: Movement disorders : official journal of the Movement Disorder Society 20120915

Title: Pesticide residues in tobacco leaves from the Kushtia district in Bangladesh.

Journal: Bulletin of environmental contamination and toxicology 20120901

Title: Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity.

Journal: Toxicology 20120816

Title: Methoxychlor inhibits growth and induces atresia through the aryl hydrocarbon receptor pathway in mouse ovarian antral follicles.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20120801

Title: Long term exposure to organochlorine pesticides and thyroid function in children from Cidade dos Meninos, Rio de Janeiro, Brazil.

Journal: Environmental research 20120801

Title: Epigenetic mechanisms in the actions of endocrine-disrupting chemicals: gonadal effects and role in female reproduction.

Journal: Reproduction in domestic animals = Zuchthygiene 20120801

Title: Effects of pesticides used in agriculture on the development of precocious puberty.

Journal: Environmental monitoring and assessment 20120701

Title: Induced growth of BG-1 ovarian cancer cells by 17β-estradiol or various endocrine disrupting chemicals was reversed by resveratrol via downregulation of cell cycle progression.

Journal: Molecular medicine reports 20120701

Title: Levels and seasonal variations of organochlorine pesticides in urban and rural background air of southern Ghana.

Journal: Environmental science and pollution research international 20120701

Title: Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicity.

Journal: Toxicology and applied pharmacology 20120615

Title: Distribution of organochlorine pesticides (OCs) and polychlorinated biphenyls (PCBs) in marine sediments directly exposed to wastewater from Cortiou, Marseille.

Journal: Environmental science and pollution research international 20120601

Title: Characterization of endocrine-disrupting chemicals based on hormonal balance disruption in male and female adult rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20120601

Title: Estrogen receptor alpha overexpressing mouse antral follicles are sensitive to atresia induced by methoxychlor and its metabolites.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20120601

Title: Methoxychlor-induced ovarian follicle toxicity in mice: dose and exposure duration-dependent effects.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20120601

Title: Quantification of steroids and endocrine disrupting chemicals in rat ovaries by LC-MS/MS for reproductive toxicology assessment.

Journal: Analytical and bioanalytical chemistry 20120601

Title: Treatment with bisphenol A and methoxychlor results in the growth of human breast cancer cells and alteration of the expression of cell cycle-related genes, cyclin D1 and p21, via an estrogen receptor-dependent signaling pathway.

Journal: International journal of molecular medicine 20120501

Title: Seasonal variation, sources, and gas/particle concentrations of PCBs and OCPs at high altitude suburban site in Western Black Sea Region of Turkey.

Journal: Journal of environmental monitoring : JEM 20120501

Title: Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology.

Journal: The Journal of biological chemistry 20120302

Title: Determination of organochlorine pesticides and polychlorinated biphenyls in post-mortem human lung by matrix solid-phase dispersion with the aid of response surface methodology and desirability function.

Journal: Journal of chromatography. A 20120302

Title: Pollution by organochlorine pesticides in Navachiste-Macapule, Sinaloa, Mexico.

Journal: Environmental monitoring and assessment 20120301

Title: Risk posed by chlorinated organic compounds in Abu Qir Bay, East Alexandria, Egypt.

Journal: Environmental science and pollution research international 20120301

Title: Organochlorine pesticides and polychlorinated biphenyls in sediments and fish from freshwater cultured fish ponds in different agricultural contexts in north-eastern France.

Journal: Ecotoxicology and environmental safety 20120301

Title: Multi-residue analysis of free and conjugated hormones and endocrine disruptors in rat testis by QuEChERS-based extraction and LC-MS/MS.

Journal: Analytical and bioanalytical chemistry 20120301

Title: Two-generation reproduction toxicity study in rats with methoxychlor.

Journal: Congenital anomalies 20120301

Title: Thyroid Hormone-disrupting Effects and the Amphibian Metamorphosis Assay.

Journal: Journal of toxicologic pathology 20120301

Title: Biomarker genes for detecting estrogenic activity of endocrine disruptors via estrogen receptors.

Journal: International journal of environmental research and public health 20120301

Title: Reductive dechlorination of methoxychlor by bacterial species of environmental origin: evidence for primary biodegradation of methoxychlor in submerged environments.

Journal: Journal of agricultural and food chemistry 20120227

Title: Roles of reactive oxygen species and antioxidants in ovarian toxicity.

Journal: Biology of reproduction 20120201

Title: A comparison of two human cell lines and two rat gonadal cell primary cultures as in vitro screening tools for aromatase modulation.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120201

Title: Association of hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) with in vitro fertilization (IVF) outcomes.

Journal: Environmental health perspectives 20120201

Title: European birth cohorts for environmental health research.

Journal: Environmental health perspectives 20120101

Title: Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems.

Journal: Journal of neuroendocrinology 20120101

Title: Determination of organochlorine pesticide residue in sediment and water from the Densu river basin, Ghana.

Journal: Chemosphere 20120101

Title: An environmental fate study of methoxychlor using water-sediment model system.

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: Pregnane X receptor and yin yang 1 contribute to the differential tissue expression and induction of CYP3A5 and CYP3A4.

Journal: PloS one 20120101

Title: Transgenerational actions of environmental compounds on reproductive disease and identification of epigenetic biomarkers of ancestral exposures.

Journal: PloS one 20120101

Title: Development of on-line high performance liquid chromatography (HPLC)-biochemical detection methods as tools in the identification of bioactives.

Journal: International journal of molecular sciences 20120101

Title: Applications for next-generation sequencing in fish ecotoxicogenomics.

Journal: Frontiers in genetics 20120101

Title: Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.

Journal: PloS one 20120101

Title: Use of comprehensive screening methods to detect selective human CAR activators.

Journal: Biochemical pharmacology 20111215

Title: Neonatal injections of methoxychlor decrease adult rat female reproductive behavior.

Journal: Neurotoxicology 20111201

Title: Early-life soy exposure and gender-role play behavior in children.

Journal: Environmental health perspectives 20111201

Title: Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging.

Journal: Molecular endocrinology (Baltimore, Md.) 20111201

Title: Prior or coinstantaneous oral exposure to environmental immunosuppressive agents aggravates mite allergen-induced atopic dermatitis-like immunoreaction in NC/Nga mice.

Journal: Toxicology 20111118

Title: Environmental impact on vascular development predicted by high-throughput screening.

Journal: Environmental health perspectives 20111101

Title: Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling.

Journal: Reproduction (Cambridge, England) 20111101

Title: Bioconcentration and biotransformation of [¹⁴C]methoxychlor in the brackish water bivalve Corbicula japonica.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110901

Title: Concentrations of trace elements [corrected] and organochlorines in Mutton bird (Puffinus griseus).

Journal: Ecotoxicology and environmental safety 20110901

Title: Current assessment of the effects of environmental chemicals on the mammary gland in guideline rodent studies by the U.S. Environmental Protection Agency (U.S. EPA), Organisation for Economic Co-operation and Development (OECD), and National Toxicology Program (NTP).

Journal: Environmental health perspectives 20110801

Title: Chemical genomics profiling of environmental chemical modulation of human nuclear receptors.

Journal: Environmental health perspectives 20110801

Title: Environmental exposures and mammary gland development: state of the science, public health implications, and research recommendations.

Journal: Environmental health perspectives 20110801

Title: Distribution characteristics of organochlorine pesticides in surface and vertical sediments from the Zha Long Wetland, China.

Journal: Environmental science and pollution research international 20110801

Title: Organochlorine pesticide residues in strawberries from integrated pest management and organic farming.

Journal: Journal of agricultural and food chemistry 20110727

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Journal: Chemical research in toxicology 20110718

Title: Pesticides removal from waste water by activated carbon prepared from waste rubber tire.

Journal: Water research 20110701

Title: The methoxychlor metabolite, HPTE, inhibits rat luteal cell progesterone production.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20110701

Title: Methoxychlor reduces estradiol levels by altering steroidogenesis and metabolism in mouse antral follicles in vitro.

Journal: Toxicology and applied pharmacology 20110615

Title: Persistent organic pollutants in ringed seals from the Russian Arctic.

Journal: The Science of the total environment 20110615

Title: Prior exposure to immunosuppressive organophosphorus or organochlorine compounds aggravates the T(H)1- and T(H)2-type allergy caused by topical sensitization to 2,4-dinitrochlorobenzene and trimellitic anhydride.

Journal: Journal of immunotoxicology 20110601

Title: Gene alterations of ovarian cancer cells expressing estrogen receptors by estrogen and bisphenol a using microarray analysis.

Journal: Laboratory animal research 20110601

Title: Effects of early prepubertal exposure to bisphenol A on the onset of puberty, ovarian weights, and estrous cycle in female mice.

Journal: Clinical and experimental reproductive medicine 20110601

Title: Effect of methoxychlor on Ca2+ handling and viability in OC2 human oral cancer cells.

Journal: Basic & clinical pharmacology & toxicology 20110501

Title: Effects of methoxychlor and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase-3 activities in human and rat testes.

Journal: International journal of andrology 20110401

Title: Pesticide residues in fruits at the market level in Accra Metropolis, Ghana, a preliminary study.

Journal: Environmental monitoring and assessment 20110401

Title: Increased sensitivity of estrogen receptor alpha overexpressing antral follicles to methoxychlor and its metabolites.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401

Title: Detection of thymocytes apoptosis in mice induced by organochlorine pesticides methoxychlor.

Journal: Immunopharmacology and immunotoxicology 20110301

Title: Effects of environmental endocrine disruptors on pubertal development.

Journal: Journal of clinical research in pediatric endocrinology 20110301

Title: Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.

Journal: Toxicology 20110227

Title: Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes.

Journal: Reproduction (Cambridge, England) 20110201

Title: Methoxychlor affects multiple hormone signaling pathways in the largemouth bass (Micropterus salmoides) liver.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20110201

Title: Estrogenic activity of bisphenol A and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) demonstrated in mouse uterine gene profiles.

Journal: Environmental health perspectives 20110101

Title: Combinations of physiologic estrogens with xenoestrogens alter ERK phosphorylation profiles in rat pituitary cells.

Journal: Environmental health perspectives 20110101

Title: Selecting adequate exposure biomarkers of diisononyl and diisodecyl phthalates: data from the 2005-2006 National Health and Nutrition Examination Survey.

Journal: Environmental health perspectives 20110101

Title: Atmospheric organochlorine pesticide (OCP) levels in a metropolitan city in Turkey.

Journal: Chemosphere 20110101

Title: Epigenetics, spermatogenesis and male infertility.

Journal: Mutation research 20110101

Title: The organophosphate Chlorpyrifos interferes with the responses to 17β-estradiol in the digestive gland of the marine mussel Mytilus galloprovincialis.

Journal: PloS one 20110101

Title: Persistent organic pollutants in serum and several different fat compartments in humans.

Journal: Journal of environmental and public health 20110101

Title: Endocrine disruptors: Ubiquitous, yet less known.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Hippobosca longipennis--a potential intermediate host of a species of Acanthocheilonema in dogs in northern India.

Journal: Parasites & vectors 20110101

Title: Neuroendocrine disruption: more than hormones are upset.

Journal: Journal of toxicology and environmental health. Part B, Critical reviews 20110101

Title: Neuroendocrine impacts of endocrine-disrupting chemicals in birds: life stage and species sensitivities.

Journal: Journal of toxicology and environmental health. Part B, Critical reviews 20110101

Title: Do Thyroid Disrupting Chemicals Influence Foetal Development during Pregnancy?

Journal: Journal of thyroid research 20110101

Title: In vivo induction of oocyte maturation and ovulation in zebrafish.

Journal: PloS one 20110101

Title: Chemical exposure as etiology in developmental origin of adult onset human cancer.

Journal: Frontiers in pharmacology 20110101

Title: 3D-QSPR method of computational technique applied on red reactive dyes by using CoMFA strategy.

Journal: International journal of molecular sciences 20110101

Title: Prior exposure to organophosphorus and organochlorine pesticides increases the allergic potential of environmental chemical allergens in a local lymph node assay.

Journal: Toxicology letters 20101215

Title: Endocrine profiling and prioritization of environmental chemicals using ToxCast data.

Journal: Environmental health perspectives 20101201

Title: Prioritizing research for trace pollutants and emerging contaminants in the freshwater environment.

Journal: Environmental pollution (Barking, Essex : 1987) 20101201

Title: Adding insult to injury: effects of xenobiotic-induced preantral ovotoxicity on ovarian development and oocyte fusibility.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201

Title: Mono-hydroxy methoxychlor alters levels of key sex steroids and steroidogenic enzymes in cultured mouse antral follicles.

Journal: Toxicology and applied pharmacology 20101201

Title: Potential occupational exposures in the Reiss-Engelhorn-Museen Mannheim/Germany.

Journal: Bulletin of environmental contamination and toxicology 20101201

Title: Screening chemicals for thyroid-disrupting activity: A critical comparison of mammalian and amphibian models.

Journal: Critical reviews in toxicology 20101101

Title: Bisphenol AF is a full agonist for the estrogen receptor ERalpha but a highly specific antagonist for ERbeta.

Journal: Environmental health perspectives 20100901

Title: Developmental programming: impact of fetal exposure to endocrine-disrupting chemicals on gonadotropin-releasing hormone and estrogen receptor mRNA in sheep hypothalamus.

Journal: Toxicology and applied pharmacology 20100901

Title: [Determination of methoxychlor in rabbit serum and its metabolic products with high performance liquid chromatography].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20100801

Title: Current use pesticides in Arctic media; 2000-2007.

Journal: The Science of the total environment 20100701

Title: Novel facile detection of persistent organic pollutants using highly sensitive gas sensor.

Journal: Talanta 20100630

Title: Organochlorine pesticide residues in wheat from Konya region, Turkey.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100501

Title: Methoxychlor induces apoptosis via mitochondria- and FasL-mediated pathways in adult rat testis.

Journal: Chemico-biological interactions 20100429

Title: Endocrine disruptors targeting ERbeta function.

Journal: International journal of andrology 20100401

Title: Developmental reprogramming of reproductive and metabolic dysfunction in sheep: native steroids vs. environmental steroid receptor modulators.

Journal: International journal of andrology 20100401

Title: Small scale variability of chlorinated POPs in the river Elbe floodplain soils (Germany).

Journal: Chemosphere 20100401

Title: Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.

Journal: Chemical research in toxicology 20100315

Title: Apoptosis in immunocytes induced by several types of pesticides.

Journal: Journal of immunotoxicology 20100301

Title: Association of low-dose exposure to persistent organic pollutants with global DNA hypomethylation in healthy Koreans.

Journal: Environmental health perspectives 20100301

Title: Environmental levels of para-nonylphenol are able to affect cytokine secretion in human placenta.

Journal: Environmental health perspectives 20100301

Title: Metabolism of methoxychlor by the P450-monooxygenase CYP6G1 involved in insecticide resistance of Drosophila melanogaster after expression in cell cultures of Nicotiana tabacum.

Journal: Chemistry & biodiversity 20100301

Title: Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.

Journal: Toxicology letters 20100215

Title: Anaerobic biodegradation of organochlorine pesticides in contaminated soil - significance of temperature and availability.

Journal: Chemosphere 20100101

Title: Residential pesticides and childhood leukemia: a systematic review and meta-analysis.

Journal: Environmental health perspectives 20100101

Title: Bioremediation of chlorinated pesticide-contaminated soil using anaerobic sludges and surfactant addition.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20100101

Title: Genetic and epigenetic insights into fetal alcohol spectrum disorders.

Journal: Genome medicine 20100101

Title: Self-reported chemicals exposure, beliefs about disease causation, and risk of breast cancer in the Cape Cod Breast Cancer and Environment Study: a case-control study.

Journal: Environmental health : a global access science source 20100101

Title: Hormonal action of plant derived and anthropogenic non-steroidal estrogenic compounds: phytoestrogens and xenoestrogens.

Journal: Current medicinal chemistry 20100101

Title: Bisphenol a exposure in Mexico City and risk of prematurity: a pilot nested case control study.

Journal: Environmental health : a global access science source 20100101

Title: Toxic impacts of cypermethrin on behavior and histology of certain tissues of albino rats.

Journal: Toxicology international 20100101

Title: Bioassay of estrogenic compounds in transgenic Arabidopsis plants carrying a recombinant human estrogen receptor gene and a GFP reporter gene.

Journal: Transgenic research 20091201

Title: Tiered aquatic ecological risk assessment of organochlorine pesticides and their mixture in Jiangsu reach of Huaihe River, China.

Journal: Environmental monitoring and assessment 20091001

Title: Fetal and neonatal exposure to the endocrine disruptor methoxychlor causes epigenetic alterations in adult ovarian genes.

Journal: Endocrinology 20091001

Title: Methoxychlor inhibits growth of antral follicles by altering cell cycle regulators.

Journal: Toxicology and applied pharmacology 20091001

Title: Metabolism of methoxychlor by Cunninghamella elegans ATCC36112.

Journal: Journal of agricultural and food chemistry 20090909

Title: Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells.

Journal: Environmental health perspectives 20090801

Title: PCB and organochlorine pesticides in home-produced eggs in Belgium.

Journal: The Science of the total environment 20090715

Title: Effect of the methoxychlor metabolite HPTE on the rat ovarian granulosa cell transcriptome in vitro.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090701

Title: Residential exposure to polychlorinated biphenyls and organochlorine pesticides and risk of childhood leukemia.

Journal: Environmental health perspectives 20090601

Title: Characterization of spatial repellent, contact irritant, and toxicant chemical actions of standard vector control compounds.

Journal: Journal of the American Mosquito Control Association 20090601

Title: Environmental contaminants in freshwater fish and their risk to piscivorous wildlife based on a national monitoring program.

Journal: Environmental monitoring and assessment 20090501

Title: Monitoring of residual pesticides in herbal drug materials of Korea and China.

Journal: Bulletin of environmental contamination and toxicology 20090501

Title: Organochlorine pesticides levels in Portuguese coastal areas.

Journal: Chemosphere 20090501

Title: Polyphosphate-doped polypyrrole coated on steel fiber for the solid-phase microextraction of organochlorine pesticides in water.

Journal: Analytica chimica acta 20090413

Title: Influence of dietary Coexposure to benzo(a)pyrene on the biotransformation and distribution of 14C-methoxychlor in the channel catfish (Ictalurus punctatus).

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090401

Title: Predicting plasma concentrations of bisphenol A in children younger than 2 years of age after typical feeding schedules, using a physiologically based toxicokinetic model.

Journal: Environmental health perspectives 20090401

Title: Phenolic compounds protect cultured hippocampal neurons against ethanol-withdrawal induced oxidative stress.

Journal: International journal of molecular sciences 20090401

Title: Effects of the organochlorine pesticide methoxychlor on dopamine metabolites and transporters in the mouse brain.

Journal: Neurotoxicology 20090301

Title: Developmental toxicity and brain aromatase induction by high genistein concentrations in zebrafish embryos.

Journal: Toxicology mechanisms and methods 20090301

Title: Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38.

Journal: The Journal of reproduction and development 20090201

Title: Analysis of endocrine disruption in Southern California coastal fish using an aquatic multispecies microarray.

Journal: Environmental health perspectives 20090201

Title: Levels and distribution of persistent organochlorine pesticide residues in water and sediments of Gomti River (India)--a tributary of the Ganges River.

Journal: Environmental monitoring and assessment 20090101

Title: A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090101

Title: Persistent organohalogen contaminants in plasma from groups of humans with different occupations in Bangladesh.

Journal: Chemosphere 20090101

Title: Methoxychlor-induced alteration in the levels of HSP70 and clusterin is accompanied with oxidative stress in adult rat testis.

Journal: Journal of biochemical and molecular toxicology 20090101

Title: The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.

Journal: Nuclear receptor signaling 20090101

Title: Perinatal exposure to xenoestrogens affects pain in adult female rats.

Journal: Neurotoxicology and teratology 20090101

Title: Revealing genes associated with vitellogenesis in the liver of the zebrafish (Danio rerio) by transcriptome profiling.

Journal: BMC genomics 20090101

Title: Serum and follicular fluid organochlorine concentrations among women undergoing assisted reproduction technologies.

Journal: Environmental health : a global access science source 20090101

Title: Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.

Journal: Reproductive biology and endocrinology : RB&E 20090101

Title: Metabolomics approach to risk assessment: methoxyclor exposure in rats.

Journal: Journal of toxicology and environmental health. Part A 20090101

Title: Ru(III)-based compounds with sulfur donor ligands: synthesis, characterization, electrochemical behaviour and anticancer activity.

Journal: Dalton transactions (Cambridge, England : 2003) 20081221

Title: Development of a stable dual cell-line GFP expression system to study estrogenic endocrine disruptors.

Journal: Biotechnology and bioengineering 20081215

Title: Organochlorine pesticide residues in plankton, Rangsit agricultural area, central Thailand.

Journal: Bulletin of environmental contamination and toxicology 20081201

Title: Developmental methoxychlor exposure affects multiple reproductive parameters and ovarian folliculogenesis and gene expression in adult rats.

Journal: Toxicology and applied pharmacology 20081201

Title: [Characterization of free and bound organochlorine pesticides in four soil/sediments of the Pearl River Delta, China].

Journal: Huan jing ke xue= Huanjing kexue 20081201

Title: Ligand specificity of constitutive androstane receptor as probed by induced-fit docking and mutagenesis.

Journal: Journal of medicinal chemistry 20081127

Title: Transient inhibitory effect of methoxychlor on testicular steroidogenesis in rat: an in vivo study.

Journal: Archives of toxicology 20081101

Title: Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit.

Journal: Environmental health perspectives 20081101

Title: Occurrence, distribution and possible sources of organochlorine pesticide residues in tropical coastal environment of India: an overview.

Journal: Environment international 20081001

Title: The use of metabolising systems for in vitro testing of endocrine disruptors.

Journal: Current drug metabolism 20081001

Title: Hydroxylated metabolites of the polybrominated diphenyl ether mixture DE-71 are weak estrogen receptor-alpha ligands.

Journal: Environmental health perspectives 20081001

Title: Methoxychlor and estradiol induce oxidative stress DNA damage in the mouse ovarian surface epithelium.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080901

Title: In silico description of differential enantioselectivity in methoxychlor O-demethylation by CYP2C enzymes.

Journal: Biochimica et biophysica acta 20080901

Title: Prenatal phenol and phthalate exposures and birth outcomes.

Journal: Environmental health perspectives 20080801

Title: Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701

Title: Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species.

Journal: Environmental health perspectives 20080701

Title: Dependence of persistence and long-range transport potential on gas-particle partitioning in multimedia models.

Journal: Environmental science & technology 20080515

Title: The role of early life genistein exposures in modifying breast cancer risk.

Journal: British journal of cancer 20080506

Title: Toxic effects of methoxychlor administered subcutaneously on the hypothalamic-pituitary-testicular axis in adult rats.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080501

Title: A simple and rapid matrix-assisted laser desorption/ionization time of flight mass spectrometry method to screen fish plasma samples for estrogen-responsive biomarkers.

Journal: Environmental toxicology and chemistry 20080501

Title: In utero exposure to low doses of environmental pollutants disrupts fetal ovarian development in sheep.

Journal: Molecular human reproduction 20080501

Title: Reductive dechlorination of methoxychlor and DDT by human intestinal bacterium Eubacterium limosum under anaerobic conditions.

Journal: Archives of environmental contamination and toxicology 20080401

Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

Journal: Chemical research in toxicology 20080401

Title: In vivo and in vitro effects of the organochlorine pesticides DDT, TCPM, methoxychlor, and lindane on the female reproductive tract of mammals: a review.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20080401

Title: Effects of the pesticide methoxychlor on gene expression in the liver and testes of the male largemouth bass (Micropterus salmoides).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080326

Title: Pesticides removal in the process of drinking water production.

Journal: Chemosphere 20080301

Title: Mechanisms of interaction of endocrine-disrupting chemicals with glutamate-evoked secretion of gonadotropin-releasing hormone.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080301

Title: Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling.

Journal: FEMS immunology and medical microbiology 20080301

Title: Chemical contaminants, health indicators, and reproductive biomarker responses in fish from rivers in the Southeastern United States.

Journal: The Science of the total environment 20080215

Title: Removal of endosulfan and methoxychlor from water on carbon slurry.

Journal: Environmental science & technology 20080201

Title: Glucuronidation and sulfonation, in vitro, of the major endocrine-active metabolites of methoxychlor in the channel catfish, Ictalurus punctatus, and induction following treatment with 3-methylcholanthrene.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080131

Title: Stimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-a, and beta-b by methoxychlor and its mono- and bis-demethylated metabolites in HepG2 cells.

Journal: The Journal of steroid biochemistry and molecular biology 20080101

Title: The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20080101

Title: Household vacuum cleaners vs. the high-volume surface sampler for collection of carpet dust samples in epidemiologic studies of children.

Journal: Environmental health : a global access science source 20080101

Title: The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells.

Journal: PloS one 20080101

Title: Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice.

Journal: BMC physiology 20080101

Title: Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.

Journal: Molecular brain 20080101

Title: Transgenerational epigenetic programming of the brain transcriptome and anxiety behavior.

Journal: PloS one 20080101

Title: Antioxidant systems and oxidative stress in the testes.

Journal: Oxidative medicine and cellular longevity 20080101

Title: Online in situ analysis of selected semi-volatile organic compounds in water by automated microscale solid-phase extraction with large-volume injection/gas chromatography/mass spectrometry.

Journal: Journal of chromatography. A 20071228

Title: Occurrence and distribution of persistent trace organics in rainwater in an urban region (India).

Journal: Bulletin of environmental contamination and toxicology 20071201

Title: Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening.

Journal: Chemical research in toxicology 20071201

Title: Human exposure to endocrine-disrupting chemicals and prenatal risk factors for cryptorchidism and hypospadias: a nested case-control study.

Journal: Environmental health perspectives 20071201

Title: Estrogen sensitivity of target genes and expression of nuclear receptor co-regulators in rat prostate after pre- and postnatal exposure to the ultraviolet filter 4-methylbenzylidene camphor.

Journal: Environmental health perspectives 20071201

Title: Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review.

Journal: Environmental health perspectives 20071201

Title: Activity of xenoestrogens at nanomolar concentrations in the E-Screen assay.

Journal: Environmental health perspectives 20071201

Title: Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals.

Journal: Environmental health perspectives 20071201

Title: Mixture effects of estrogenic compounds on proliferation and pS2 expression of MCF-7 human breast cancer cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071101

Title: Organochlorine pesticide contamination in three bird species of the Embalse La Florida water reservoir in the semiarid midwest of Argentina.

Journal: The Science of the total environment 20071015

Title: Effects of xenoestrogens on the differentiation of behaviorally-relevant neural circuits.

Journal: Frontiers in neuroendocrinology 20071001

Title: Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20070921

Title: Developmental exposure to low-dose estrogenic endocrine disruptors alters sex differences in exploration and emotional responses in mice.

Journal: Hormones and behavior 20070901

Title: Environmental exposures and gene regulation in disease etiology.

Journal: Environmental health perspectives 20070901

Title: The pesticide methoxychlor decreases myotube formation in cell culture by slowing myoblast proliferation.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070801

Title: Methoxychlor suppresses the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible CYP1A1 expression in murine Hepa-1c1c7 cells.

Journal: Journal of toxicology and environmental health. Part A 20070801

Title: Methoxychlor and its metabolites inhibit growth and induce atresia of baboon antral follicles.

Journal: Toxicologic pathology 20070801

Title: Determination of organochlorine pesticides in ground water samples using solid-phase microextraction by gas chromatography-electron capture detection.

Journal: Talanta 20070731

Title: Organochlorine pesticides in placentas from Southern Spain and some related factors.

Journal: Placenta 20070701

Title: Chemical contaminants, health indicators, and reproductive biomarker responses in fish from the Colorado River and its tributaries.

Journal: The Science of the total environment 20070601

Title: Organochlorine pesticides in freshwater fish from the Zagreb area.

Journal: Arhiv za higijenu rada i toksikologiju 20070601

Title: Organochlorine pesticides in seafood products from southern China and health risk assessment.

Journal: Environmental toxicology and chemistry 20070601

Title: Estradiol and Bisphenol A stimulate androgen receptor and estrogen receptor gene expression in fetal mouse prostate mesenchyme cells.

Journal: Environmental health perspectives 20070601

Title: Residues of persistent organochlorine contaminants in southern elephant seals (Mirounga leonina) from Elephant Island, Antarctica.

Journal: Environmental science & technology 20070601

Title: Toxic effects of methoxychlor in rat striatum: modifications in several neurotransmitters.

Journal: Journal of physiology and biochemistry 20070601

Title: Residues of organochlorine pesticides in near shore waters of LaiZhou Bay and JiaoZhou Bay, Shandong Peninsula, China.

Journal: Chemosphere 20070501

Title: Residues of organochlorine pesticides in fish from the Gomti river, India.

Journal: Bulletin of environmental contamination and toxicology 20070501

Title: [Simultaneous determination of nine organochlorine pesticide residues in textile by high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20070501

Title: Estrogenic effects of mixtures of phyto- and synthetic chemicals on uterine growth of prepubertal rats.

Journal: Toxicology letters 20070425

Title: Calbindin-D9k mRNA expression in the rat uterus following exposure to methoxychlor: a comparison of oral and subcutaneous exposure.

Journal: The Journal of reproduction and development 20070401

Title: From mother to child: investigation of prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring.

Journal: Chemosphere 20070401

Title: Perinatal bisphenol A exposure increases estrogen sensitivity of the mammary gland in diverse mouse strains.

Journal: Environmental health perspectives 20070401

Title: Residues of organochlorinated pesticides in soils from the Czech Republic.

Journal: Environmental pollution (Barking, Essex : 1987) 20070301

Title: Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen.

Journal: Journal of veterinary science 20070301

Title: Persistent organochlorine pesticide residues in soil and surface water of northern Indo-Gangetic alluvial plains.

Journal: Environmental monitoring and assessment 20070201

Title: Metals and organochlorine pesticides in caudal scutes of crocodiles from Belize and Costa Rica.

Journal: The Science of the total environment 20070201

Title: Exposure of young men to organochlorine pesticides in Southern Spain.

Journal: Environmental research 20070101

Title: A proteomic (SELDI-TOF-MS) approach to estrogen agonist screening.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070101

Title: In silico prediction of pregnane X receptor activators by machine learning approaches.

Journal: Molecular pharmacology 20070101

Title: Appropriate 'housekeeping' genes for use in expression profiling the effects of environmental estrogens in fish.

Journal: BMC molecular biology 20070101

Title: Pesticide content in drinking water samples collected from orchard areas in central Poland.

Journal: Annals of agricultural and environmental medicine : AAEM 20070101

Title: Determining the transrepression activity of xenoestrogen on nuclear factor-kappa B in Cos-1 cells by estrogen receptor-alpha.

Journal: International journal of toxicology 20070101

Title: Developmental programming: differential effects of prenatal exposure to bisphenol-A or methoxychlor on reproductive function.

Journal: Endocrinology 20061201

Title: Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption.

Journal: The Journal of steroid biochemistry and molecular biology 20061201

Title: Early postnatal methoxychlor exposure inhibits folliculogenesis and stimulates anti-Mullerian hormone production in the rat ovary.

Journal: The Journal of endocrinology 20061201

Title: Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.

Journal: Toxicology 20061110

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Organochlorine contaminants in complete clutches of Morelet's crocodile (Crocodylus moreletii) eggs from Belize.

Journal: Environmental pollution (Barking, Essex : 1987) 20061101

Title: The methoxychlor metabolite, 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits steroidogenesis in rat ovarian granulosa cells in vitro.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20061101

Title: Methoxychlor causes mitochondrial dysfunction and oxidative damage in the mouse ovary.

Journal: Toxicology and applied pharmacology 20061101

Title: Experimental parameters affecting sensitivity and specificity of a yeast assay for estrogenic compounds: results of an interlaboratory validation exercise.

Journal: Analytical and bioanalytical chemistry 20061101

Title: Fertile grounds of inquiry: environmental effects on human reproduction.

Journal: Environmental health perspectives 20061101

Title: Methoxychlor inhibits growth and induces atresia of antral follicles through an oxidative stress pathway.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20061001

Title: Effects of possible endocrine disrupting chemicals on bacterial component-induced activation of NF-kappaB.

Journal: Biological & pharmaceutical bulletin 20061001

Title: Agricultural pesticide use and hypospadias in eastern Arkansas.

Journal: Environmental health perspectives 20061001

Title: Analytical methods for PCBs and organochlorine pesticides in environmental monitoring and surveillance: a critical appraisal.

Journal: Analytical and bioanalytical chemistry 20061001

Title: Microwave-assisted extraction through an aqueous medium and simultaneous cleanup by partition on hexane for determining pesticides in agricultural soils by gas chromatography: a critical study.

Journal: Analytica chimica acta 20060925

Title: Methoxychlor metabolites may cause ovarian toxicity through estrogen-regulated pathways.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060901

Title: Methoxychlor induces atresia of antral follicles in ERalpha-overexpressing mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060901

Title: Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines.

Journal: Life sciences 20060815

Title: Evoecotoxicology: environmental changes and life features development during the evolutionary process-the record of the past at developmental stages of living organisms.

Journal: Environmental health perspectives 20060801

Title: PAH-DNA adducts in cord blood and fetal and child development in a Chinese cohort.

Journal: Environmental health perspectives 20060801

Title: Determination of organochlorine pesticides and polychlorinated biphenyls in chicken eggs by matrix solid phase dispersion.

Journal: Analytica chimica acta 20060728

Title: Persistent pesticides in human breast milk and cryptorchidism.

Journal: Environmental health perspectives 20060701

Title: Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601

Title: Endocrine regulation of HOX genes.

Journal: Endocrine reviews 20060601

Title: NTP multigenerational study of environmental estrogens.

Journal: Environmental health perspectives 20060601

Title: Estrogenic effects in vitro and in vivo of the fungicide fenarimol.

Journal: Toxicology letters 20060525

Title: Altered mammary gland development in male rats exposed to genistein and methoxychlor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration.

Journal: Brain research 20060407

Title: Rapid action of pesticides on cytosolic calcium concentrations in cultures of human umbilical vein endothelial cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20060401

Title: Perinatal immunotoxicity: why adult exposure assessment fails to predict risk.

Journal: Environmental health perspectives 20060401

Title: Endocrine disrupting contaminants--beyond the dogma.

Journal: Environmental health perspectives 20060401

Title: Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?

Journal: Environmental health perspectives 20060401

Title: Screening and testing for endocrine disruption in fish-biomarkers as 'signposts,' not 'traffic lights,' in risk assessment.

Journal: Environmental health perspectives 20060401

Title: Modeling the demographic effects of endocrine disruptors.

Journal: Environmental health perspectives 20060401

Title: Viewpoint: Policy requirements for protecting wildlife from endocrine disruptors.

Journal: Environmental health perspectives 20060401

Title: Epigenetics: the science of change.

Journal: Environmental health perspectives 20060301

Title: Reproductive abnormalities in adult male mice following preimplantation exposures to estradiol or pesticide methoxychlor.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20060201

Title: In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol side-chain cleavage activity.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20060201

Title: Effect of methoxychlor and estradiol on cytochrome p450 enzymes in the mouse ovarian surface epithelium.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060201

Title: Rapid effects of pesticides on human granulosa-lutein cells.

Journal: Reproduction (Cambridge, England) 20060201

Title: Perinatal exposure to endocrine disrupting compounds alters behavior and brain in the female pine vole.

Journal: Neurotoxicology and teratology 20060101

Title: A case for revisiting the safety of pesticides: a closer look at neurodevelopment.

Journal: Environmental health perspectives 20060101

Title: Regression analysis of pesticide use and breast cancer incidence in California Latinas.

Journal: Journal of environmental health 20060101

Title: Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action.

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Toxic effects of methoxychlor on the episodic prolactin secretory pattern: possible mediated effects of nitric oxide production.

Journal: Journal of circadian rhythms 20060101

Title: David Kupfer: a career retrospective.

Journal: Drug metabolism reviews 20060101

Title: David Kupfer, Ph.D. A mentor and a scientist.

Journal: Drug metabolism reviews 20060101

Title: Activated estrogens and antiestrogens: a 30-year journey with David Kupfer.

Journal: Drug metabolism reviews 20060101

Title: Pesticide exposure: the hormonal function of the female reproductive system disrupted?

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Biodegradation of methoxychlor and its metabolites by the white rot fungus Stereum hirsutum related to the inactivation of estrogenic activity.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20060101

Title: Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals.

Journal: Reproductive biology and endocrinology : RB&E 20060101

Title: Validation study of OECD rodent uterotrophic assay for the assessment of estrogenic activity in Sprague-Dawley immature female rats.

Journal: Journal of toxicology and environmental health. Part A 20051210

Title: Screening 31 endocrine-disrupting pesticides in water and surface sediment samples from Beijing Guanting reservoir.

Journal: Chemosphere 20051201

Title: Spatial trends and factors affecting variation of organochlorine contaminants levels in Canadian Arctic beluga (Delphinapterus leucas).

Journal: The Science of the total environment 20051201

Title: Methoxychlor inhibits brain mitochondrial respiration and increases hydrogen peroxide production and CREB phosphorylation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051201

Title: The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.

Journal: PLoS genetics 20051201

Title: Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors.

Journal: Annals of the New York Academy of Sciences 20051201

Title: Development of estrogen-responsive transgenic medaka for environmental monitoring of endocrine disrupters.

Journal: Environmental science & technology 20051115

Title: Methoxychlor directly affects ovarian antral follicle growth and atresia through Bcl-2- and Bax-mediated pathways.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051101

Title: Comparison of relative binding affinities of endocrine active compounds to fathead minnow and rainbow trout estrogen receptors.

Journal: Environmental toxicology and chemistry 20051101

Title: Impact of maternal dietary exposure to endocrine-acting chemicals on progesterone receptor expression in microdissected hypothalamic medial preoptic areas of rat offspring.

Journal: Toxicology and applied pharmacology 20051015

Title: Are EDCs blurring issues of gender?

Journal: Environmental health perspectives 20051001

Title: Fundamental flaws of hormesis for public health decisions.

Journal: Environmental health perspectives 20051001

Title: Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines.

Journal: Environmental health perspectives 20051001

Title: Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.

Journal: Journal of medicinal chemistry 20050908

Title: Sulfonation of environmental chemicals and their metabolites in the polar bear (Ursus maritimus).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050901

Title: Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901

Title: CAR and PXR: xenosensors of endocrine disrupters?

Journal: Chemico-biological interactions 20050815

Title: Methoxychlor-induced inducible nitric oxide synthase and proinflammatory cytokines expression in macrophages via NF-kappaB, ERK, and p38 mitogen-activated protein kinases.

Journal: Biochemical and biophysical research communications 20050812

Title: Methoxychlor disrupts uterine Hoxa10 gene expression.

Journal: Endocrinology 20050801

Title: Myelotoxicity in genistein-, nonylphenol-, methoxychlor-, vinclozolin- or ethinyl estradiol-exposed F1 generations of Sprague-Dawley rats following developmental and adult exposures.

Journal: Toxicology 20050801

Title: Consequences of endocrine disrupting chemicals on reproductive endocrine function in birds: establishing reliable end points of exposure.

Journal: Domestic animal endocrinology 20050801

Title: An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment.

Journal: Environmental health perspectives 20050801

Title: Endocrine-disrupting chemicals probed as potential pathways to illness.

Journal: JAMA 20050720

Title: Comparative in vitro metabolism of methoxychlor in male and female rats: metabolism of demethylated methoxychlor metabolites by precision-cut rat liver slices.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050701

Title: Developmental biology. Endocrine disrupters trigger fertility problems in multiple generations.

Journal: Science (New York, N.Y.) 20050603

Title: Epigenetic transgenerational actions of endocrine disruptors and male fertility.

Journal: Science (New York, N.Y.) 20050603

Title: Accurate prediction of the response of freshwater fish to a mixture of estrogenic chemicals.

Journal: Environmental health perspectives 20050601

Title: Effects of selected xenoestrogens on liver peroxisomes, vitellogenin levels and spermatogenic cell proliferation in male zebrafish.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050601

Title: [Establishment of reporter gene-based assays for the identification of (anti) androgenic effects of chemicals in CHO cells].

Journal: Wei sheng yan jiu = Journal of hygiene research 20050501

Title: [Distribution of organochlorine pesticides in surface sediments from Huangpu River and its risk evaluation].

Journal: Huan jing ke xue= Huanjing kexue 20050501

Title: Assessing the consequences of the pesticide methoxychlor: neuroendocrine and behavioral measures as indicators of biological impact of an estrogenic environmental chemical.

Journal: Brain research bulletin 20050415

Title: D-amphetamine-related reinforcing effects are reduced in mice exposed prenatally to estrogenic endocrine disruptors.

Journal: Brain research bulletin 20050415

Title: Embryonic co-exposure to methoxychlor and Clophen A50 alters sexual behavior in adult male quail.

Journal: Archives of toxicology 20050401

Title: Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population.

Journal: Environmental health perspectives 20050401

Title: Comparative in vitro metabolism of the suspected pro-oestrogenic compound, methoxychlor in precision-cut liver slices from male and female rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050401

Title: Organochlorine insecticides: impacts on human HepG2 cytochrome P4501A, 2B activities and glutathione levels.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20050301

Title: Necessity to measure PCBs and organochlorine pesticide concentrations in human umbilical cords for fetal exposure assessment.

Journal: Environmental health perspectives 20050301

Title: Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice.

Journal: Environmental health perspectives 20050301

Title: Organochlorine pesticides and mercury in cottonmouths (Agkistrodon piscivorus) from northeastern Texas, USA.

Journal: Environmental toxicology and chemistry 20050301

Title: Dietary methoxychlor exposure modulates splenic natural killer cell activity, antibody-forming cell response and phenotypic marker expression in F0 and F1 generations of Sprague Dawley rats.

Journal: Toxicology 20050214

Title: Methoxychlor induces proliferation of the mouse ovarian surface epithelium.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050201

Title: Effects of environmental and natural estrogens on vitellogenin production in hepatocytes of the brown frog (Rana temporaria).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20050118

Title: High volume bioassays to assess CYP3A4-mediated drug interactions: induction and inhibition in a single cell line.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101

Title: Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050101

Title: Interactions between CYP2C9 and CYP2C19 in reconstituted binary systems influence their catalytic activity: possible rationale for the inability of CYP2C19 to catalyze methoxychlor demethylation in human liver microsomes.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101

Title: A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity.

Journal: Toxicology and applied pharmacology 20050101

Title: Lepidium meyenii (Maca) increases litter size in normal adult female mice.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Longitudinal assessment of PCBs and chlorinated pesticides in pregnant women from Western Canada.

Journal: Environmental health : a global access science source 20050101

Title: Residues of endosulfan and other selected organochlorine pesticides in farm areas of the Lower Fraser Valley, British Columbia, Canada.

Journal: Journal of environmental quality 20050101

Title: Estrogen regulation of testicular function.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Smoking and reproduction: the oviduct as a target of cigarette smoke.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: The reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits testosterone formation by cultured Leydig cells from neonatal rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101

Title: Biochemical characterization of the Arctic char (Salvelinus alpinus) ovarian progestin membrane receptor.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Biology and physiology of Calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Induction and inhibition of oocyte maturation by EDCs in zebrafish.

Journal: Reproductive biology and endocrinology : RB&E 20050101

Title: Identification of health hazards to rural population living near pesticide dump sites in Poland.

Journal: International journal of occupational medicine and environmental health 20050101

Title: A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.

Journal: Biochemical pharmacology 20041215

Title: Endocrine disruption in adolescence: immunologic, hematologic, and bone effects in monkeys.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041201

Title: Use of trout liver slices to enhance mechanistic interpretation of estrogen receptor binding for cost-effective prioritization of chemicals within large inventories.

Journal: Environmental science & technology 20041201

Title: Chitinase activity in the epidermis of the fiddler crab, Uca pugilator, as an in vivo screen for molt-interfering xenobiotics.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041201

Title: The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20041101

Title: Androgenic and estrogenic response of green mussel extracts from Singapore's coastal environment using a human cell-based bioassay.

Journal: Environmental health perspectives 20041101

Title: In vivo imaging of activated estrogen receptors in utero by estrogens and bisphenol A.

Journal: Environmental health perspectives 20041101

Title: Gene expression profiles in mammary gland of male rats treated with genistein and methoxychlor.

Journal: Environmental toxicology and pharmacology 20041101

Title: Evaluation of the developmental and reproductive toxicity of methoxychlor using an anuran (Xenopus tropicalis) chronic exposure model.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041001

Title: Effect of methoxychlor on various life stages of Xenopus laevis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041001

Title: Posthatch methoxychlor exposure adversely affects reproduction of adult zebra finches, Taeniopygia guttata.

Journal: Bulletin of environmental contamination and toxicology 20041001

Title: Chlorobenzenes, chlorinated pesticides, coplanar chlorobiphenyls and other organochlorine compounds in Greenland biota.

Journal: The Science of the total environment 20040920

Title: Effects of natural and synthetic estrogens and various environmental contaminants on vitellogenesis in fish primary hepatocytes: comparison of bream (Abramis brama) and carp (Cyprinus carpio).

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040901

Title: Exposure of women to organochlorine pesticides in Southern Spain.

Journal: Environmental research 20040901

Title: Bayesian multivariate logistic regression.

Journal: Biometrics 20040901

Title: Estrogenic and toxic effects of methoxychlor on zebrafish (Danio rerio).

Journal: Environmental toxicology and chemistry 20040901

Title: Acute toxicity of sediment-sorbed endrin, methoxychlor, and endosulfan to Hyalella azteca and Chironomus tentans.

Journal: Bulletin of environmental contamination and toxicology 20040901

Title: Behavioral alterations in response to fear-provoking stimuli and tranylcypromine induced by perinatal exposure to bisphenol A and nonylphenol in male rats.

Journal: Environmental health perspectives 20040801

Title: Effects of methoxychlor exposure during perinatal period on reproductive function after maturation in rats.

Journal: The Journal of reproduction and development 20040801

Title: Interactive effects of p,p'-dichlorodiphenyldichloroethylene and methoxychlor on hormone synthesis in largemouth bass ovarian cultures.

Journal: Environmental toxicology and chemistry 20040801

Title: In vitro metabolism of [14C]methoxychlor in rat, mouse, Japanese quail and rainbow trout in precision-cut liver slices.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040801

Title: A novel flexible approach for evaluating fixed ratio mixtures of full and partial agonists.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040701

Title: Glucuronidation of the oxidative cytochrome P450-mediated phenolic metabolites of the endocrine disruptor pesticide: methoxychlor by human hepatic UDP-glucuronosyl transferases.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701

Title: Organochlorine pesticides in chorioallantoic membranes of Morelet's crocodile eggs from belize.

Journal: Journal of wildlife diseases 20040701

Title: Methoxychlor-induced atresia in the mouse involves Bcl-2 family members, but not gonadotropins or estradiol.

Journal: Biology of reproduction 20040601

Title: Effect of three xenobiotic compounds on Glutathione S-Transferase in the clam Ruditapes decussatus.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040528

Title: Sexually dimorphic basal water absorption at the isolated pelvic patch of Japanese tree frog, Hyla japonica.

Journal: Journal of experimental zoology. Part A, Comparative experimental biology 20040501

Title: Using a customized DNA microarray for expression profiling of the estrogen-responsive genes to evaluate estrogen activity among natural estrogens and industrial chemicals.

Journal: Environmental health perspectives 20040501

Title: Estimation of estrogenic and antiestrogenic activities of selected pesticides by MCF-7 cell proliferation assay.

Journal: Archives of environmental contamination and toxicology 20040501

Title: Methoxychlor-induced alterations in the histological expression of angiogenic factors in pituitary and uterus.

Journal: Journal of molecular histology 20040501

Title: Alteration of pituitary hormone-immunoreactive cell populations in rat offspring after maternal dietary exposure to endocrine-active chemicals.

Journal: Archives of toxicology 20040401

Title: Oxidative dechlorination of methoxychlor by ligninolytic enzymes from white-rot fungi.

Journal: Chemosphere 20040401

Title: Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.

Journal: Environmental health perspectives 20040401

Title: Sensitivity of the immature rat uterotrophic assay to mixtures of estrogens.

Journal: Environmental health perspectives 20040401

Title: Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors.

Journal: Biochemical and biophysical research communications 20040312

Title: Determination of organochlorine compounds in human biological samples by GC-MS/MS.

Journal: Biomedical chromatography : BMC 20040301

Title: Effects of methoxychlor, dieldrin and lindane on sea urchin fertilization and early development.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20040225

Title: Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors.

Journal: Analytical and bioanalytical chemistry 20040201

Title: Enantioselective recognition of mono-demethylated methoxychlor metabolites by the estrogen receptor.

Journal: Chemosphere 20040201

Title: CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: use of inhibitory monoclonal antibodies in P450 identification.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040201

Title: Organochlorinated compounds in Caspian Sea sediments.

Journal: Marine pollution bulletin 20040101

Title: Maternal concentration of polychlorinated biphenyls and dichlorodiphenyl dichlorethylene and birth weight in Michigan fish eaters: a cohort study.

Journal: Environmental health : a global access science source 20040101

Title: Preimplantation exposures of murine embryos to estradiol or methoxychlor change postnatal development.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040101

Title: Phytoestrogen genistein and its pharmacological interactions with synthetic endocrine-active compounds.

Journal: Current pharmaceutical design 20040101

Title: Endocrine disruption and cognitive function in adolescent female rhesus monkeys.

Journal: Neurotoxicology and teratology 20040101

Title: Carcinogen-metabolizing enzymes and insecticides.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20040101

Title: Dual action of oestrogens on the mouse constitutive androstane receptor.

Journal: The Biochemical journal 20031201

Title: Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor.

Journal: Toxicology and applied pharmacology 20031115

Title: Impact of dietary exposure to methoxychlor, genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive systems in later life.

Journal: Toxicology 20031105

Title: Distinct molecular conformations of the estrogen receptor alpha complex exploited by environmental estrogens.

Journal: Cancer research 20031101

Title: Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust.

Journal: Environmental science & technology 20031015

Title: Determination of the estrogenic and antiestrogenic effects of environmental contaminants in chicken embryo hepatocyte cultures by quantitative-polymerase chain reaction.

Journal: Environmental toxicology and chemistry 20031001

Title: Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.

Journal: Chemical research in toxicology 20031001

Title: Determination of organochlorine pesticides in water using microwave assisted headspace solid-phase microextraction and gas chromatography.

Journal: Journal of chromatography. A 20030919

Title: Hepatic CYP1A, 2B, 2C, 2E and 3A regulation by methoxychlor in male and female rats.

Journal: Toxicology letters 20030915

Title: Isolation of four aquatic streptomycetes strains capable of growth on organochlorine pesticides.

Journal: Bioresource technology 20030901

Title: Fate and assessment of persistent organic pollutants in water and sediment from Minjiang River Estuary, Southeast China.

Journal: Chemosphere 20030901

Title: The OECD program to validate the rat uterotrophic bioassay: an overview.

Journal: Environmental health perspectives 20030901

Title: The OECD program to validate the rat uterotrophic bioassay. Phase 2: dose-response studies.

Journal: Environmental health perspectives 20030901

Title: The OECD program to validate the rat uterotrophic bioassay. Phase 2: coded single-dose studies.

Journal: Environmental health perspectives 20030901

Title: Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701

Title: Estrogenic endocrine disruptive components interfere with calcium handling and differentiation of human trophoblast cells.

Journal: Journal of cellular biochemistry 20030701

Title: Evaluation of alternative tactics for management of insecticide-resistant horn flies (Diptera: Muscidae).

Journal: Journal of economic entomology 20030601

Title: Resistance status of house flies (Diptera: Muscidae) from southeastern Nebraska beef cattle feedlots to selected insecticides.

Journal: Journal of economic entomology 20030601

Title: Effect of organochlorine pesticides on maturation of starfish and mouse oocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030501

Title: Analysis of pesticides in water and sediment under different storage conditions using gas chromatography.

Journal: Archives of environmental contamination and toxicology 20030501

Title: Methoxychlor modifies the ultradian secretory pattern of prolactin and affects its TRH response.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20030501

Title: The multidrug resistance-associated protein 1 transports methoxychlor and protects the seminiferous epithelium from injury.

Journal: Toxicology letters 20030430

Title: Environmental estrogens alter early development in Xenopus laevis.

Journal: Environmental health perspectives 20030401

Title: Inhibition of gonadotropin-induced oviposition and ovarian steroidogenesis in the African clawed frog (Xenopus laevis) by the pesticide methoxychlor.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20030212

Title: Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.

Journal: Archives of biochemistry and biophysics 20030101

Title: Preimplantation mouse embryo development as a target of the pesticide methoxychlor.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20030101

Title: [Contents of organochlorine pesticides in water, pore water and sediment in Minjiang River Estuary of China].

Journal: Huan jing ke xue= Huanjing kexue 20030101

Title: Expression profiling of estrogenic compounds using a sheepshead minnow cDNA macroarray.

Journal: EHP toxicogenomics : journal of the National Institute of Environmental Health Sciences 20030101

Title: Effect of transient embryonic in vivo exposure to the endocrine disruptor methoxychlor on embryonic and postnatal testis development.

Journal: Journal of andrology 20030101

Title: Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts.

Journal: Environmental health : a global access science source 20030101

Title: Animal models of ovarian cancer.

Journal: Reproductive biology and endocrinology : RB&E 20030101

Title: Enantioselective metabolism of the endocrine disruptor pesticide methoxychlor by human cytochromes P450 (P450s): major differences in selective enantiomer formation by various P450 isoforms.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201

Title: Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor.

Journal: Archives of toxicology 20021201

Title: Increases in mouse uterine heat shock protein levels are a sensitive and specific response to uterotrophic agents.

Journal: Environmental health perspectives 20021201

Title: An avian bioassay for environmental estrogens: the growth response of zebra finch (Taeniopygia guttata) chick oviduct to oral estrogens.

Journal: Environmental toxicology and chemistry 20021201

Title: Determination of estrogenic activity in landfill leachate by simplified yeast two-hybrid assay.

Journal: Journal of environmental monitoring : JEM 20021201

Title: A binary screening assay for pro-oestrogens in food: metabolic activation using hepatic microsomes and detection with oestrogen sensitive recombinant yeast cells.

Journal: Food additives and contaminants 20021201

Title: Effect of xenoestrogen exposure on the expression of cytochrome P450 isoforms in rainbow trout liver.

Journal: Environmental toxicology and chemistry 20021101

Title: Thymic atrophy induced by methoxychlor in rat pups.

Journal: Toxicology letters 20021005

Title: A comparison of the estrogenic potencies of estradiol, ethynylestradiol, diethylstilbestrol, nonylphenol and methoxychlor in vivo and in vitro.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20021002

Title: Effect of tolerance to insecticides on substrate penetration by Formosan subterranean termites (Isoptera: Rhinotermitidae).

Journal: Journal of economic entomology 20021001

Title: Metabolism of the endocrine disruptor pesticide-methoxychlor by human P450s: pathways involving a novel catechol metabolite.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20020901

Title: Determination of organochlorine pesticides in seawater using liquid-phase hollow fibre membrane microextraction and gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20020830

Title: Uterine responsiveness to estradiol and DNA methylation are altered by fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice: effects of low versus high doses.

Journal: Toxicology and applied pharmacology 20020815

Title: Analysis of pesticides and PCB congeners in serum by GC/MS with SPE sample cleanup.

Journal: Toxicology letters 20020805

Title: Methoxychlor may cause ovarian follicular atresia and proliferation of the ovarian epithelium in the mouse.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020801

Title: Persistent chlorinated pesticides in fish and cattle fat and their implications for human serum concentrations from the Sene-Gambian region.

Journal: Journal of environmental monitoring : JEM 20020801

Title: Detection of estrogenic activity in sediment-associated compounds using in vitro reporter gene assays.

Journal: The Science of the total environment 20020703

Title: Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis.

Journal: Toxicology 20020701

Title: Is exposure to endocrine disrupting compounds during fetal/post-natal development affecting the reproductive potential of farm animals?

Journal: Domestic animal endocrinology 20020701

Title: Enhancing effects of beta-estradiol 3-benzoate but not methoxychlor on the promotion/progression stage of chemically-induced mammary carcinogenesis in ovariectomized rats.

Journal: Japanese journal of cancer research : Gann 20020701

Title: Workshop report. Children as a special subpopulation: focus on immunotoxicity. Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV), 15-16 November 2001, Berlin, Germany.

Journal: Archives of toxicology 20020701

Title: Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids.

Journal: Bioscience, biotechnology, and biochemistry 20020701

Title: Organochlorine pesticides directly regulate gonadotropin-releasing hormone gene expression and biosynthesis in the GT1-7 hypothalamic cell line.

Journal: Molecular and cellular endocrinology 20020628

Title: Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020601

Title: Methoxychlor alters the predator-prey relationship between dragonfly naiads and salamander larvae.

Journal: Bulletin of environmental contamination and toxicology 20020601

Title: Effects of primary exposure to environmental and natural estrogens on vitellogenin production in carp (Cyprinus carpio) hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020501

Title: Effects of subchronic exposure to a complex mixture of persistent contaminants in male rats: systemic, immune, and reproductive effects.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020501

Title: PCDDs/PCDFs, PCBs, and organochlorine pesticides in eggs of Eurasian sparrowhawks (Accipiter nisus), hobbies (Falco subbuteo), and northern goshawks (Accipiter gentilis) collected in the area of Berlin-Brandenburg, Germany.

Journal: Archives of environmental contamination and toxicology 20020501

Title: Comparative assessment of endocrine modulators with oestrogenic activity. II. Persistent organochlorine pollutants.

Journal: Archives of toxicology 20020501

Title: The hidden effect of estrogenic/antiandrogenic methoxychlor on spermatogenesis.

Journal: Toxicology and applied pharmacology 20020415

Title: Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats.

Journal: Cancer letters 20020408

Title: Genistein and methoxychlor modulate the activity of natural killer cells and the expression of phenotypic markers by thymocytes and splenocytes in F0 and F1 generations of Sprague-Dawley rats.

Journal: Toxicology 20020402

Title: Modulation of mammary gland development in prepubertal male rats exposed to genistein and methoxychlor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020401

Title: Assessment of interactions of diverse ternary mixtures in an estrogen receptor-alpha reporter assay.

Journal: Toxicology and applied pharmacology 20020401

Title: Oral estrogen masculinizes female zebra finch song system.

Journal: Hormones and behavior 20020301

Title: Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020301

Title: Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020301

Title: The pesticide methoxychlor disrupts the fusion of myoblasts into myotubes in skeletal muscle cell culture.

Journal: Toxicology and applied pharmacology 20020301

Title: Utility of a juvenile fathead minnow screening assay for detecting (anti-)estrogenic substances.

Journal: Environmental toxicology and chemistry 20020201

Title: Altered behaviors in male mice, male quail, and salamander larvae following early exposures to the estrogenic pesticide methoxychlor.

Journal: Neurotoxicology and teratology 20020101

Title: Ethological methods to study the effects of maternal exposure to estrogenic endocrine disrupters: a study with methoxychlor.

Journal: Neurotoxicology and teratology 20020101

Title: Endocrine disruption caused by two common pollutants at 'acceptable' concentrations.

Journal: Neurotoxicology and teratology 20020101

Title: Cognitive testing (delayed non-match to sample) during oral treatment of female adolescent monkeys with the estrogenic pesticide methoxychlor.

Journal: Neurotoxicology and teratology 20020101

Title: Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich element.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101

Title: The effect of methoxychlor on the epididymal antioxidant system of adult rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20020101

Title: The rat as a model in developmental immunotoxicology.

Journal: Human & experimental toxicology 20020101

Title: The pesticide methoxychlor given orally during the perinatal/juvenile period, reduced the spermatogenic potential of males as adults by reducing their Sertoli cell number.

Journal: Reproduction, nutrition, development 20020101

Title: Effect of methoxychlor on antioxidant system of goat epididymal sperm in vitro.

Journal: Asian journal of andrology 20011201

Title: Response of MCF-7 human breast cancer cells to some binary mixtures of oestrogenic compounds in-vitro.

Journal: The Journal of pharmacy and pharmacology 20011101

Title: Diet and organochlorine contaminants in women of reproductive age under 40 years old.

Journal: Early human development 20011101

Title: Analysis of organochlorine pesticides in human milk: preliminary results.

Journal: Early human development 20011101

Title: A repeated 28-day oral dose toxicity study of methoxychlor in rats, based on the 'enhanced OECD test guideline 407' for screening endocrine-disrupting chemicals.

Journal: Archives of toxicology 20011101

Title: Halogenated organic contaminants in sediments of the Havel and Spree rivers (Germany). Part 5 of organic compounds as contaminants of the Elbe river and its tributaries.

Journal: Environmental science & technology 20011015

Title: Insecticide susceptibility in Coptotermes formosanus and Reticulitermes virginicus (Isoptera: Rhinotermitidae).

Journal: Journal of economic entomology 20011001

Title: Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010901

Title: Effects of prenatal exposure to low doses of diethylstilbestrol, o,p'DDT, and methoxychlor on postnatal growth and neurobehavioral development in male and female mice.

Journal: Hormones and behavior 20010901

Title: Metabolic activation of bisphenol A by rat liver S9 fraction.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010801

Title: Optimization of a yeast estrogen screen and its applicability to study the release of estrogenic isoflavones from a soygerm powder.

Journal: Environmental health perspectives 20010701

Title: Determination of pesticides in drinking water by micellar electrokinetic capillary chromatography.

Journal: Electrophoresis 20010701

Title: Assessing the biological potency of binary mixtures of environmental estrogens using vitellogenin induction in juvenile rainbow trout (Oncorhynchus mykiss).

Journal: Environmental science & technology 20010615

Title: Application of static liquid-phase microextraction to the analysis of organochlorine pesticides in water.

Journal: Journal of chromatography. A 20010615

Title: Mechanism of induction of cytochrome p450 enzymes by the proestrogenic endocrine disruptor pesticide-methoxychlor: interactions of methoxychlor metabolites with the constitutive androstane receptor system.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601

Title: Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas).

Journal: Environmental toxicology and chemistry 20010601

Title: Effects of nutrient loading and planktivory on the accumulation of organochlorine pesticides in aquatic food chains.

Journal: Environmental toxicology and chemistry 20010601

Title: Identification of selected hormonally active agents and animal mammary carcinogens in commercial and residential air and dust samples.

Journal: Journal of the Air & Waste Management Association (1995) 20010401

Title: Inhibition of basal and stimulated progesterone synthesis by dichlorodiphenyldichloroethylene and methoxychlor in a stable pig granulosa cell line.

Journal: Reproduction (Cambridge, England) 20010301

Title: Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

Journal: Chemical research in toxicology 20010301

Title: Environmental toxicant effects on neuroendocrine function.

Journal: Endocrine 20010301

Title: Assessment of the effects of metabolism on the estrogenic activity of xenoestrogens: a two-stage approach coupling human liver microsomes and a yeast estrogenicity assay.

Journal: The Journal of pharmacology and experimental therapeutics 20010201

Title: Effects of p-nonylphenol, methoxychlor, and endosulfan on vitellogenin induction and expression in sheepshead minnow (Cyprinodon variegatus).

Journal: Environmental toxicology and chemistry 20010201

Title: An in vitro reporter gene assay method incorporating metabolic activation with human and rat S9 or liver microsomes.

Journal: Biochemical and biophysical research communications 20010112

Title: Cell response endpoints enhance sensitivity of the immature mouse uterotropic assay.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101

Title: Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis growth.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101

Title: The diverse mechanism of action of dichlorodiphenyldichloroethylene (DDE) and methoxychlor in ovarian cells in vitro.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101

Title: Differential estrogen receptor binding of estrogenic substances: a species comparison.

Journal: The Journal of steroid biochemistry and molecular biology 20001115

Title: Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20001101

Title: Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies.

Journal: Molecular pharmacology 20001001

Title: Estradiol and pesticide methoxychlor do not exhibit additivity or synergism in the reproductive tract of adult ovariectomized mice.

Journal: Journal of toxicology and environmental health. Part A 20000728

Title: Effect of methoxychlor administration to male rats on hepatic, microsomal iodothyronine 5'-deiodinase, form I.

Journal: The Journal of pharmacology and experimental therapeutics 20000701

Title: Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20000401

Title: A metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme.

Journal: Biology of reproduction 20000301

Title: Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta.

Journal: Endocrinology 19991201

Title: Estrogen directly respresses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-alpha (ERalpha)- and ERbeta-expressing GT1-7 GnRH neurons.

Journal: Endocrinology 19991101

Title: Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (non-ER) alpha and non-ER beta mechanism.

Journal: Endocrinology 19990801

Title: Growth stimulation of a rat pituitary cell line MtT/E-2 by environmental estrogens in vitro and in vivo.

Journal: Endocrine journal 19990801

Title: Monospecific antipeptide antibody to cytochrome P-450 2B6.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19990401

Title: Low-dose bioactivity of xenoestrogens in animals: fetal exposure to low doses of methoxychlor and other xenoestrogens increases adult prostate size in mice.

Journal: Toxicology and industrial health 19990101

Title: Methoxychlor given in the periimplantation period blocks sexual arousal in male mice.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19990101

Title: Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19990101

Title: Comparative estrogenic activity of wine extracts and organochlorine pesticide residues in food.

Journal: Environmental health perspectives 19981201

Title: Estrogenic xenobiotics increase expression of SS-A/Ro autoantigens in cultured human epidermal cells.

Journal: Acta dermato-venereologica 19981101

Title: Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.

Journal: Endocrinology 19981001

Title: Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19980901

Title: Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.

Journal: Toxicology and applied pharmacology 19980701

Title: Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoforms.

Journal: Biochemical pharmacology 19980601

Title: Identification of estrogen receptor beta2, a functional variant of estrogen receptor beta expressed in normal rat tissues.

Journal: Endocrinology 19980301

Title: Mechanism of induction of rat hepatic CYP2B and 3A by the pesticide methoxychlor.

Journal: Journal of biochemical and molecular toxicology 19980101

Title: Neonatal exposure to technical methoxychlor alters pregnancy outcome in female mice.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19980101

Title: Xenobiotic interaction with and alteration of channel catfish estrogen receptor.

Journal: Toxicology and applied pharmacology 19971201

Title: The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune, and reproductive system function.

Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology 19971101

Title: Influence of beta-naphthoflavone and methoxychlor pretreatment on the biotransformation and estrogenic activity of methoxychlor in channel catfish (Ictalurus punctatus).

Journal: Toxicology and applied pharmacology 19970801

Title: Examination of purported probes of human CYP2B6.

Journal: Pharmacogenetics 19970601

Title: Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay.

Journal: Toxicology and applied pharmacology 19970301

Title: Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins.

Journal: Environmental health perspectives 19970301

Title: Catalytic characteristics of CYP3A4: requirement for a phenolic function in ortho hydroxylation of estradiol and mono-O-demethylated methoxychlor.

Journal: Biochemistry 19970225

Title: Estradiol or methoxychlor stimulates estrogen receptor (ER) expression in uteri.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19960101

Title: Methoxychlor mimics the action of 17 beta-estradiol on induction of uterine epidermal growth factor receptors in immature female rats.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19960101

Title: Cytochrome P450 catalyzed covalent binding of methoxychlor to rat hepatic, microsomal iodothyronine 5'-monodeiodinase, type I: does exposure to methoxychlor disrupt thyroid hormone metabolism?

Journal: Archives of biochemistry and biophysics 19951001

Title: Effects of estrogen, progesterone, and methoxychlor on surgically induced endometriosis in rats.

Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology 19950901

Title: Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behaviour in male mice.

Journal: Toxicology letters 19950501

Title: Induction of the hepatic CYP2B and CYP3A enzymes by the proestrogenic pesticide methoxychlor and by DDT in the rat. Effects on methoxychlor metabolism.

Journal: Journal of biochemical toxicology 19950201

Title: Neonatal exposures to technical methoxychlor alters ovaries in adult mice.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19950101

Title: Methoxychlor regulates rat uterine estrogen-induced protein.

Journal: Toxicology and applied pharmacology 19950101

Title: Effects of methoxychlor on skin tumor development.

Journal: Toxicology letters 19941201

Title: Metabolism of the proestrogenic pesticide methoxychlor by hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2B.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19940101

Title: Reversible and time-dependent inhibition of the hepatic cytochrome P450 steroidal hydroxylases by the proestrogenic pesticide methoxychlor in rat and human.

Journal: Journal of biochemical toxicology 19931201

Title: Substrate-binding region of cytochrome P-450SCC (P-450 XIA1). Identification and primary structure of the cholesterol binding region in cytochrome P-450SCC.

Journal: Biochimica et biophysica acta 19930213

Title: Influence of bromfenvinphos alone, and in mixture with methoxychlor, on levels of gamma-glutamyl transpeptidase, ceruloplasmin and cholesterol in the blood plasma of laboratory mice.

Journal: Polish journal of pharmacology 19930101

Title: Purified methoxychlor stimulates the reproductive tract in immature female mice.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19930101

Title: Effect of methoxychlor on ovarian steroidogenesis: role in early pregnancy loss.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19930101

Title: Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19920101

Title: Effects of methoxychlor treatment of pregnant mice on female offspring of the treated and subsequent pregnancies.

Journal: Reproductive toxicology (Elmsford, N.Y.) 19920101

Title: Morphological and biochemical alterations in reproductive tracts of neonatal female mice treated with the pesticide methoxychlor.

Journal: Biology of reproduction 19900301

Title: Inhibitory effects of technical grade methoxychlor on development of neonatal male mouse reproductive organs.

Journal: Biology of reproduction 19900301

Title: A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat.

Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology 19890101

Title: Effects of low subchronic doses of methoxychlor on the rat hypothalamic-pituitary reproductive axis.

Journal: Toxicology and applied pharmacology 19861201

Title: Role of hepatic monooxygenases in generating estrogenic metabolites from methoxychlor and from its identified contaminants.

Journal: Molecular pharmacology 19850101

Title: Interstitial cell carcinomas of the testis in Balb/C male mice ingesting methoxychlor.

Journal: Journal of cancer research and clinical oncology 19790219

Title: Bilateral sudden deafness following combined insecticide poisoning.

Journal: The Laryngoscope 19780801

Title: [Textile pest control in textile stores with a combination preparation of methoxycholor and chlorpyrifos [0,0-diethyl-(3,5,6-trichloro-2-pyridyl)-monothiophosphate]].

Journal: Arzneimittel-Forschung 19770101

Title: Methoxychlor effects on hepatic storage of vitamin A in rats.

Journal: Bulletin of environmental contamination and toxicology 19760801

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Tags:72-43-5 Molecular Formula|72-43-5 MDL|72-43-5 SMILES|72-43-5 Benzene,1,1'-(2,2,2-trichloroethylidene)bis[4-methoxy- |Organic_Building_Blocks