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Title: P450s and UGTs: Key Players in the Structural Diversity of Triterpenoid Saponins.
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Title: Lanosterol biosynthesis: the critical role of the methyl-29 group of 2,3-oxidosqualene for the correct folding of this substrate and for the construction of the five-membered D ring.
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Title: Divergent evolution of oxidosqualene cyclases in plants.
Journal: The New phytologist 20120301
Title: Investigation of the potential for triterpene synthesis in rice through genome mining and metabolic engineering.
Journal: The New phytologist 20110701
Title: Assessment of the kinetics of the antioxidative capacity of topical antioxidants.
Journal: Journal of drugs in dermatology : JDD 20110301
Title: Novel pyrrole- and 1,2,3-triazole-based 2,3-oxidosqualene cyclase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20101001
Title: gamma-Tocotrienol reduces squalene hydroperoxide-induced inflammatory responses in HaCaT keratinocytes.
Journal: Lipids 20100901
Title: Squalene as a target molecule in skin hyperpigmentation caused by singlet oxygen.
Journal: Biological & pharmaceutical bulletin 20090901
Title: Conformational energetics of cationic backbone rearrangements in triterpenoid biosynthesis provide an insight into enzymatic control of product.
Journal: Journal of the American Chemical Society 20080716
Title: Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase: a chemistry-biology interdisciplinary study of the protein's structure-function-reaction mechanism relationships.
Journal: Chemical record (New York, N.Y.) 20080101
Title: Ion-trap tandem mass spectrometric analysis of squalene monohydroperoxide isomers in sunlight-exposed human skin.
Journal: Journal of lipid research 20071201
Title: Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris.
Journal: The Journal of investigative dermatology 20061101
Title: Cation-pi interaction in the polyolefin cyclization cascade uncovered by incorporating unnatural amino acids into the catalytic sites of squalene cyclase.
Journal: Journal of the American Chemical Society 20061011
Title: Lanosterol synthase in dicotyledonous plants.
Journal: Plant & cell physiology 20060501
Title: A putative precursor of isomalabaricane triterpenoids from lanosterol synthase mutants.
Journal: Organic letters 20060202
Title: Enzymatic cyclization of dioxidosqualene to heterocyclic triterpenes.
Journal: Journal of the American Chemical Society 20051228
Title: Analogs of squalene and oxidosqualene inhibit oxidosqualene cyclase of Trypanosoma cruzi expressed in Saccharomyces cerevisiae.
Journal: Lipids 20051201
Title: Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis.
Journal: The Journal of biological chemistry 20051028
Title: Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase.
Journal: Journal of the American Chemical Society 20051019
Title: Deletion of the Gly600 residue of Alicyclobacillus acidocaldarius squalene cyclase alters the substrate specificity into that of the eukaryotic-type cyclase specific to (3S)-2,3-oxidosqualene.
Journal: Angewandte Chemie (International ed. in English) 20041210
Title: Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase.
Journal: Nature 20041104
Title: Potent protecting effects of Catuaba (Anemopaegma mirandum) extracts against hydroperoxide-induced cytotoxicity.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20040601
Title: Squalene-hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade and for the formation of the 5-membered E-ring.
Journal: Organic & biomolecular chemistry 20040521
Title: Enzymatic cyclization of 22,23-dihydro-2,3-oxidosqualene into euph-7-en-3beta-ol and bacchar-12-en-3beta-ol by recombinant beta-amyrin synthase.
Journal: Journal of the American Chemical Society 20040324
Title: The monotopic membrane protein human oxidosqualene cyclase is active as monomer.
Journal: Biochemical and biophysical research communications 20040305
Title: Ultraviolet a induces generation of squalene monohydroperoxide isomers in human sebum and skin surface lipids in vitro and in vivo.
Journal: The Journal of investigative dermatology 20030601
Title: Conjugated methyl sulfide and phenyl sulfide derivatives of oxidosqualene as inhibitors of oxidosqualene and squalene-hopene cyclases.
Journal: Lipids 20030301
Title: Characteristics of skin wrinkling and dermal changes induced by repeated application of squalene monohydroperoxide to hairless mouse skin.
Journal: Skin pharmacology and applied skin physiology 20030101
Title: Effect of sunlight exposure and aging on skin surface lipids and urate.
Journal: Experimental dermatology 20030101
Title: Biosynthesis of triterpenoid saponins in plants.
Journal: Advances in biochemical engineering/biotechnology 20020101
Title: Brassinosteroids. Plant counterparts to animal steroid hormones?
Journal: Vitamins and hormones 20020101
Title: Synthesis and inhibition studies of sulfur-substituted squalene oxide analogues as mechanism-based inhibitors of 2,3-oxidosqualene-lanosterol cyclase.
Journal: Journal of medicinal chemistry 19970117
