Catalog No.:AA00FXTG

724424-43-5 | (R)-2-CHLORO-5-(4-(HYDROXY(METHOXY)METHYL)-3,5-DIOXO-4,5-DIHYDRO-1,2,4-TRIAZIN-2(3H)-YL)-N-((1-HYDROXYCYCLOHEPTYL)METHYL)BENZAMIDE

Name: Name:(R)-2-CHLORO-5-(4-(HYDROXY(METHOXY)METHYL)-3,5-DIOXO-4,5-DIHYDRO-1,2,4-TRIAZIN-2(3H)-YL)-N-((1-HYDROXYCYCLOHEPTYL)METHYL)BENZAMIDE
Brand: AABLOCKS
SKU: AA00FXTG
Availability: InStock
Rating: 90 (10 reviews)

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1mg

1 week

$301.00 $211.00

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5mg

1 week

$671.00 $470.00

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10mg

1 week

$943.00 $660.00

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25mg

1 week

$1,418.00 $992.00

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50mg

1 week

$1,875.00 $1,312.00

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100mg

1 week

$2,538.00 $1,776.00

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500mg

1 week

$5,029.00 $3,520.00

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA00FXTG

Chemical Name:

(R)-2-CHLORO-5-(4-(HYDROXY(METHOXY)METHYL)-3,5-DIOXO-4,5-DIHYDRO-1,2,4-TRIAZIN-2(3H)-YL)-N-((1-HYDROXYCYCLOHEPTYL)METHYL)BENZAMIDE

CAS Number:

724424-43-5

Molecular Formula:

C22H29ClN4O6

Molecular Weight:

480.9419

MDL Number:

MFCD27665471

SMILES:

COC[C@@H](Cn1c(=O)cnn(c1=O)c1ccc(c(c1)C(=O)NCC1(O)CCCCCC1)Cl)O

Properties

Literature

Title: Stock TC, et al. Efficacy and safety of CE-224,535, an antagonist of P2X7 receptor, in treatment of patients with rheumatoid arthritis inadequately controlled by methotrexate. J Rheumatol. 2012 Apr;39(4):720-7.

Title: Duplantier AJ, et al. Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3708-11

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