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72803-02-2,MFCD00867049
Catalog No.:AA00FDSY

72803-02-2 | Darodipine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
1 week  
$120.00   $84.00
- +
2mg
1 week  
$147.00   $103.00
- +
5mg
1 week  
$186.00   $130.00
- +
10mg
1 week  
$237.00   $166.00
- +
25mg
1 week  
$387.00   $271.00
- +
50mg
1 week  
$626.00   $438.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FDSY
Chemical Name:
Darodipine
CAS Number:
72803-02-2
Molecular Formula:
C19H21N3O5
Molecular Weight:
371.3871
MDL Number:
MFCD00867049
SMILES:
CCOC(=O)C1=C(C)NC(=C(C1c1cccc2c1non2)C(=O)OCC)C
Properties
Computed Properties
 
Complexity:
632  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
4.2  

Literature

Title: Testing of serum atherogenicity in cell cultures: questionable data published.

Journal: German medical science : GMS e-journal 20120101

Title: Brain aging in the oldest-old.

Journal: Current gerontology and geriatrics research 20100101

Title: Exercise as an intervention for the age-related decline in neural metabolic support.

Journal: Frontiers in aging neuroscience 20100101

Title: Angiogenesis in old-aged subjects after ischemic stroke: a cautionary note for investigators.

Journal: Journal of angiogenesis research 20100101

Title: Resveratrol preserves cerebrovascular density and cognitive function in aging mice.

Journal: Frontiers in aging neuroscience 20090101

Title: Aging is associated with increased collagen type IV accumulation in the basal lamina of human cerebral microvessels.

Journal: BMC neuroscience 20040101

Title: MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia.

Journal: Journal of cardiovascular pharmacology 19870701

Title: A comparison of nine calcium ion antagonists and propranolol: exercise tolerance, heart rate and ST-segment changes in patients with chronic stable angina pectoris.

Journal: European journal of clinical pharmacology 19870101

Title: Amenta F, et al. Effect of long-term treatment with the dihydropyridine-type calcium channel blocker darodipine(PY 108-068) on the cerebral capillary network in aged rats. Mech Ageing Dev. 1995 Jan 31;78(1):27-37.

Title: Vega JA, et al. Effect of treatment with the dihydropyridine-type calcium antagonist darodipine (PY 108-068) on the expression of neurofilament protein immunoreactivity in the cerebellar cortex of aged rats. Mech Ageing Dev. 1994 Aug;75(2):169-77.

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