Title: TLC determination of meloxicam in tablets and after acidic and alkaline hydrolysis.
Journal: Acta poloniae pharmaceutica 20120101
Title: Synthesis, characterization, toxicity, cytogenetic and in vivo antitumor studies of 1,1-dithiolate Cu(II) complexes with di-, tri-, tetra- amines and 1,3-thiazoles. Structure-activity correlation.
Journal: Bioorganic & medicinal chemistry 20090415
Title: 2-(4-Chloro-phen-yl)-3-methyl-N-(5-methyl-thia-zol-2-yl)butanamide.
Journal: Acta crystallographica. Section E, Structure reports online 20090101
Title: Evaluation of anti-inflammatory and antioxidant activities of copper (II) Schiff mono-base and copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole.
Journal: Journal of enzyme inhibition and medicinal chemistry 20081201
Title: Bis(2-amino-4-methyl-1,3-thia-zole-κN)dichloridocadmium(II).
Journal: Acta crystallographica. Section E, Structure reports online 20081001
Title: An improved relaxed complex scheme for receptor flexibility in computer-aided drug design.
Journal: Journal of computer-aided molecular design 20080901
Title: Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase.
Journal: Bioorganic & medicinal chemistry 20080601
Title: (Thermo)dynamic role of receptor flexibility, entropy, and motional correlation in protein-ligand binding.
Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20080516
Title: Copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole: synthesis, characterization, antiproliferative and antibacterial studies. Crystal structure of CudienOOCl2.
Journal: Journal of inorganic biochemistry 20040801
Title: Artificial protein cavities as specific ligand-binding templates: characterization of an engineered heterocyclic cation-binding site that preserves the evolved specificity of the parent protein.
Journal: Journal of molecular biology 20020125
Title: Antiproliferative activity of mixed-ligand dien-Cu(II) complexes with thiazole, thiazoline and imidazole derivatives.
Journal: Journal of inorganic biochemistry 20020101
2-Amino-5-methylthiazole serves as a key precursor in organic synthesis for the preparation of various compounds with pharmaceutical significance. It is utilized in the synthesis of acrylamide monomer, specifically 5-methyl-2-thiozyl methacrylamide (MTMAAm), which finds applications in polymer chemistry. Additionally, 2-Amino-5-methylthiazole is employed in the preparation of mixed-ligand dien-Cu(II) complexes and a new series of Schiff mono/dibase coordination compounds. These complexes exhibit potential anticancer and antibacterial activities, making 2-Amino-5-methylthiazole an important starting material in medicinal chemistry for the development of novel therapeutic agents.
