Name: Name:Atractylenolide II
Brand: AABLOCKS
SKU: AA00FACY
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00FACY

Chemical Name: Atractylenolide II

CAS Number: 73069-14-4

Molecular Formula: C15H20O2

Molecular Weight: 232.3181

MDL Number: MFCD01721423

SMILES: C=C1CCC[C@]2([C@H]1CC1=C(C)C(=O)O[C@H]1C2)C

Properties

Complexity: 432

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 3

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 17

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 0

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.9

Literature fold

Title: Simultaneous determination of atractylenolide II and atractylenolide III by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of Atractylodes Macrocephala Rhizoma extract.

Journal: Biomedical chromatography : BMC20121101

Title: Identification and quantification of the major volatile constituents in antidepressant active fraction of xiaoyaosan by gas chromatography-mass spectrometry.

Journal: Journal of ethnopharmacology20120507

Title: Sesquiterpenoids from Atractylodes macrocephala act as farnesoid X receptor and progesterone receptor modulators.

Journal: Bioorganic & medicinal chemistry letters20120315

Title: GABA(A) receptor modulators from Chinese herbal medicines traditionally applied against insomnia and anxiety.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20120215

Title: Simultaneous determination of four sesquiterpenoids in Atractylodes Macrocephala Rhizoma by GC-FID: optimisation of an ultrasound-assisted extraction by central composite design.

Journal: Phytochemical analysis : PCA20120101

Title: Determination of atractylenolide II in rat plasma by reversed-phase high-performance liquid chromatography.

Journal: Biomedical chromatography : BMC20070301

Title: Cytotoxic activity of sesquiterpenoids from Atractylodes ovata on leukemia cell lines.

Journal: Planta medica20020301

Title: Ye Y, et al. Atractylenolide II induces G1 cell-cycle arrest and apoptosis in B16 melanoma cells. J Ethnopharmacol. 2011 Jun 14;136(1):279-82.

Title: Fu XQ, et al. Inhibition of STAT3 signalling contributes to the antimelanoma action of atractylenolide II. Exp Dermatol. 2014 Nov;23(11):855-7.

73069-14-4 | Atractylenolide II