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74165-73-4,MFCD00053472
Catalog No.:AA003DUQ

74165-73-4 | 1-Amino-2-hydroxyindane

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250mg
95%
in stock  
$211.00   $148.00
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1g
95%
in stock  
$510.00   $357.00
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5g
95%
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$1,640.00   $1,148.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003DUQ
Chemical Name:
1-Amino-2-hydroxyindane
CAS Number:
74165-73-4
Molecular Formula:
C9H11NO
Molecular Weight:
149.1897
MDL Number:
MFCD00053472
SMILES:
NC1C(O)Cc2c1cccc2
Properties
Properties
 
BP:
290°C at 760 mmHg  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
149  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Undefined Atom Stereocenter Count:
2  
XLogP3:
0.2  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ASTRAZENECAPLC-WO2003/74531,2003,A1Locationinpatent:Page/Pagecolumn105

Literature

Title: Synthesis and biological evaluation of novel homochiral carbocyclic nucleosides from 1-amino-2-indanols.

Journal: Bioorganic & medicinal chemistry 20121001

Title: Stereocontrolled synthesis of substituted chiral piperidines via one-pot asymmetric 6π-azaelectrocyclization: asymmetric syntheses of (-)-dendroprimine, (+)-7-epidendroprimine, (+)-5-epidendroprimine, and (+)-5,7-epidendroprimine.

Journal: The Journal of organic chemistry 20120217

Title: The design and synthesis of novel IBiox N-heterocyclic carbene ligands derived from substituted amino-indanols.

Journal: Organic & biomolecular chemistry 20120121

Title: The role of weak hydrogen bonds in chiral recognition.

Journal: Physical chemistry chemical physics : PCCP 20111028

Title: Amino-indanol-catalyzed asymmetric Michael additions of oxindoles to protected 2-amino-1-nitroethenes for the synthesis of 3,3'-disubstituted oxindoles bearing α,β-diamino functionality.

Journal: The Journal of organic chemistry 20110520

Title: Chiral recognition in jet-cooled complexes of (1R,2S)-(+)-cis-1-amino-2-indanol and methyl lactate: on the importance of the CH...pi interaction.

Journal: Physical chemistry chemical physics : PCCP 20090921

Title: Glyceraldehyde-3-phosphate dehydrogenase-monoamine oxidase B-mediated cell death-induced by ethanol is prevented by rasagiline and 1-R-aminoindan.

Journal: Neurotoxicity research 20090801

Title: Comparative neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.

Journal: Neurotoxicity research 20090401

Title: Kinetic resolution of racemic pyrrolidine-2,5-diones using chiral oxazaborolidine catalysts.

Journal: Chemical communications (Cambridge, England) 20080521

Title: Indene-based thiazolidinethione chiral auxiliary for propionate and acetate aldol additions.

Journal: Organic letters 20080221

Title: Differential behavioral syndrome evoked in the rats after multiple doses of SSRI fluoxetine with selective MAO inhibitors rasagiline or selegiline.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080101

Title: The role of CH/pi interaction in the stabilization of less-soluble diastereomeric salt crystals.

Journal: Chemical record (New York, N.Y.) 20070101

Title: Fluorescence spectroscopy of jet-cooled chiral (+/-)-indan-1-ol and its cluster with (+/-)-methyl- and ethyl-lactate.

Journal: The Journal of chemical physics 20061107

Title: cis-1-Amino-2-indanol in drug design and applications to asymmetric processes.

Journal: Chemical reviews 20060701

Title: Synthesis of enantiomerically pure trans-(1R,2R)- and cis-(1S,2R)-1-amino-2-indanol by lipase and omega-transaminase.

Journal: Biotechnology and bioengineering 20060205

Title: Rational design of CH/pi interaction sites in a basic resolving agent.

Journal: The Journal of organic chemistry 20041029

Title: Synthetic applicability and in situ recycling of a B-methoxy oxazaborolidine catalyst derived from cis-1-amino-indan-2-ol.

Journal: Organic letters 20040805

Title: C2-symmetric inhibitors of Plasmodium falciparum plasmepsin II: synthesis and theoretical predictions.

Journal: Bioorganic & medicinal chemistry 20030815

Title: Improved synthesis of tert-butanesulfinamide suitable for large-scale production.

Journal: Organic letters 20030417

Title: Measurement of strain-dependent toxicity in the indene bioconversion using multiparameter flow cytometry.

Journal: Biotechnology and bioengineering 20030220

Title: Engineering an indene bioconversion process for the production of cis-aminoindanol: a model system for the production of chiral synthons.

Journal: Applied microbiology and biotechnology 20020801

Title: Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay.

Journal: Biochemistry 20020122

Title: Metabolic engineering of indene bioconversion in Rhodococcus sp.

Journal: Advances in biochemical engineering/biotechnology 20010101

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