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7432-28-2,MFCD00905761
Catalog No.:AA005M2I

7432-28-2 | Schizandrin

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10mg
≥98%
in stock  
$82.00   $57.00
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50mg
≥98%
in stock  
$333.00   $233.00
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100mg
≥98%
in stock  
$625.00   $437.00
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250mg
≥98%
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$1,268.00   $887.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005M2I
Chemical Name:
Schizandrin
CAS Number:
7432-28-2
Molecular Formula:
C24H32O7
Molecular Weight:
432.5067
MDL Number:
MFCD00905761
SMILES:
COc1c(OC)cc2c(c1OC)c1c(cc(c(c1OC)OC)OC)C[C@@H]([C@@](C2)(C)O)C
Properties
Properties
 
BP:
576.7°C at 760 mmHg  
Form:
Solid  
MP:
128.5℃  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
574  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
2  
XLogP3:
4  

Literature

Title: Effects of schizandrin on the expression of thymic stromal lymphopoietin in human mast cell line HMC-1.

Journal: Life sciences 20121005

Title: Schizandrin prevents damage of murine mesangial cells via blocking NADPH oxidase-induced ROS signaling in high glucose.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120301

Title: Schizandrin, an antioxidant lignan from Schisandra chinensis, ameliorates Aβ1-42-induced memory impairment in mice.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Preparation of high purity biphenyl cyclooctene lignans from Schisandra extract by ion exchange resin catalytic transformation combined with macroporous resin separation.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

Title: [Study on the chemical constituents of vinegar Schisandra chinensis].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111101

Title: Relaxant effects of Schisandra chinensis and its major lignans on agonists-induced contraction in guinea pig ileum.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20111015

Title: Inhibitory effect of schisandrin on spontaneous contraction of isolated rat colon.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110815

Title: Simultaneous and rapid determination of main lignans in different parts of Schisandra sphenanthera by micellar electrokinetic capillary chromatography.

Journal: Molecules (Basel, Switzerland) 20110503

Title: Schisandrin enhances dendrite outgrowth and synaptogenesis in primary cultured hippocampal neurons.

Journal: Journal of the science of food and agriculture 20110315

Title: Study on ionic liquid-based ultrasonic-assisted extraction of biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill.

Journal: Analytica chimica acta 20110309

Title: Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells.

Journal: Phytotherapy research : PTR 20110301

Title: Quantitative analysis of major dibenzocyclooctane lignans in Schisandrae fructus by online TLC-DART-MS.

Journal: Phytochemical analysis : PCA 20110101

Title: Enhanced oral bioavailability of Wurenchun (Fructus Schisandrae Chinensis extracts) by self-emulsifying drug delivery systems.

Journal: Drug development and industrial pharmacy 20101101

Title: Highly sensitive determination of Schisandrin and Schisandrin B in plasma of rats after administration of Wurenchun (Fructus Schisandrae Chinensis Extracts) preparations by LC-ESI-MS/MS.

Journal: Biomedical chromatography : BMC 20100601

Title: Derivatives of schisandrin with increased inhibitory potential on prostaglandin E(2) and leukotriene B(4) formation in vitro.

Journal: Bioorganic & medicinal chemistry 20100401

Title: A simple and sensitive HPLC method for the simultaneous determination of eight bioactive components and fingerprint analysis of Schisandra sphenanthera.

Journal: Analytica chimica acta 20100303

Title: CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100101

Title: [Changes of lignans' content in stems of Schisandra chinensis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091201

Title: [Selection of mobile phases for the determination of gamma-schisandrin and multi-active constituents in Schisandra chinensis and its preparations by high performance liquid chromatography].

Journal: Se pu = Chinese journal of chromatography 20090501

Title: Optimization of extraction and purification of active fractions from Schisandra chinensis (Turcz.) and its osteoblastic proliferation stimulating activity.

Journal: Phytotherapy research : PTR 20090201

Title: [Effects of schisandra on the function of the pituitary-adrenal cortex, gonadal axis and carbohydrate metabolism in rats undergoing experimental chronic psychological stress, navigation and strenuous exercise].

Journal: Zhonghua nan ke xue = National journal of andrology 20090201

Title: Nortriterpenoids and lignans from Schisandra sphenanthera.

Journal: Phytochemistry 20081101

Title: Anti-inflammatory effects of schisandrin isolated from the fruit of Schisandra chinensis Baill.

Journal: European journal of pharmacology 20080904

Title: Nordihydroguaiaretic acid autoxidation produces a schisandrin-like dibenzocyclooctadiene lignan.

Journal: Journal of natural products 20080901

Title: [Lignans from different processed products of Schisandra chinensis fruits].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080601

Title: Schizandrin protects primary cultures of rat cortical cells from glutamate-induced excitotoxicity.

Journal: Journal of pharmacological sciences 20080501

Title: Molecular mechanism of apoptosis induced by schizandrae-derived lignans in human leukemia HL-60 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080201

Title: Schizandrin reverses memory impairment in rats.

Journal: Phytotherapy research : PTR 20080101

Title: [Enzyme kinetics of schizandrin metabolism and sex differences in rat liver microsomes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070701

Title: Inhibitory effect of schizandrin on passive cutaneous anaphylaxis reaction and scratching behaviors in mice.

Journal: Biological & pharmaceutical bulletin 20070601

Title: Amyloid-beta-induced cytotoxicity of PC-12 cell was attenuated by Shengmai-san through redox regulation and outgrowth induction.

Journal: Journal of pharmacological sciences 20070501

Title: [Deterimination of schisandrin in Kadsura heteroclita (Roxb.) Craib by RP-HPLC].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20060601

Title: [Relationship between components changes and efficacy of Shengmaisan VII. Chemical dynamic change of schisandrin in Shengmaisan].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060601

Title: [Studies on extraction process of Fructus Schisandrae chinensis and Fructus Ligustri lucidi in gandening tablet].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040801

Title: Dibenzocyclooctadiene lignans from Schisandra chinensis protect primary cultures of rat cortical cells from glutamate-induced toxicity.

Journal: Journal of neuroscience research 20040501

Title: [A new bibenzyl derivative from Bletilla striata].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020301

Title: [Phytotherapeutic aspects of diseases of the circulatory system. 7. Schisandra chinensis (Turcz.) Baill.): its composition and biological activity].

Journal: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20010701

Title: The ameliorating effect of the water layer of Fructus Schisandrae on cycloheximide-induced amnesia in rats: interaction with drugs acting at neurotransmitter receptors.

Journal: Pharmacological research 20010101

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