Home Other Building Blocks 743461-65-6
743461-65-6,MFCD27987925
Catalog No.:AA00FFN1

743461-65-6 | Batefenterol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$70.00   $49.00
- +
5mg
≥98%
in stock  
$289.00   $202.00
- +
10mg
≥98%
in stock  
$543.00   $380.00
- +
25mg
98%
in stock  
$1,159.00   $812.00
- +
50mg
98%
in stock  
$1,574.00   $1,102.00
- +
100mg
98%
in stock  
$2,366.00   $1,657.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FFN1
Chemical Name:
Batefenterol
CAS Number:
743461-65-6
Molecular Formula:
C40H42ClN5O7
Molecular Weight:
740.2438
MDL Number:
MFCD27987925
SMILES:
COc1cc(NC(=O)CCN2CCC(CC2)OC(=O)Nc2ccccc2c2ccccc2)c(cc1CNC[C@@H](c1ccc(c2c1ccc(n2)O)O)O)Cl
Properties
Computed Properties
 
Complexity:
1230  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
53  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
14  
XLogP3:
4.4  

Literature

Title: Hegde SS, et al. Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties. J Pharmacol Exp Ther. 2014 Oct;351(1):190-9.

Title: Hughes AD, et al. Discovery of (R)-1-(3-((2-chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl ,1'-biphenyl-2-ylcarbamate (TD-5959, GSK961081, batefenterol): first-in-class dual pharmacology multivalent muscarinic antagonist and β? agonist (MABA) for the treatment of chronic obstructive pulmonary disease (COPD). J Med Chem. 2015 Mar 26;58(6):2609-22.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 743461-65-6
Tags:743461-65-6 Molecular Formula|743461-65-6 MDL|743461-65-6 SMILES|743461-65-6 Batefenterol