75176-37-3,MFCD00865919
Catalog No.:AA008NQV

75176-37-3 | L-Proline,1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-, (4S)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$286.00   $200.00
- +
5mg
≥95%
in stock  
$1,126.00   $788.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008NQV
Chemical Name:
L-Proline,1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-, (4S)-
CAS Number:
75176-37-3
Molecular Formula:
C15H19NO3S2
Molecular Weight:
325.4463
MDL Number:
MFCD00865919
SMILES:
SC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)Sc1ccccc1)C
Properties
Computed Properties
 
Complexity:
385  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.6  

Literature

Title: Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of zofenopril and its active metabolite zofenoprilat in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20110601

Title: Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Effects of antihypertensive drugs on alcohol-induced functional responses of cultured human endothelial cells.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080201

Title: Fibroblast growth factor-2 mediates Angiotensin-converting enzyme inhibitor-induced angiogenesis in coronary endothelium.

Journal: The Journal of pharmacology and experimental therapeutics 20061101

Title: Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase.

Journal: Biochemistry 20060314

Title: The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.

Journal: European journal of endocrinology 20060201

Title: Hydrochlorothiazide increases plasma or tissue angiotensin-converting enzyme-inhibitor drug levels in rats with myocardial infarction: differential effects on lisinopril and zofenopril.

Journal: European journal of pharmacology 20051219

Title: Zofenoprilat-glutathione mixed disulfide as a specific S-thiolating agent of bovine lens aldose reductase.

Journal: Antioxidants & redox signaling 20050101

Title: 11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat.

Journal: Bioorganic & medicinal chemistry 20040201

Title: Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines.

Journal: Journal of medicinal chemistry 19880601

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SDS
Tags:75176-37-3 Molecular Formula|75176-37-3 MDL|75176-37-3 SMILES|75176-37-3 L-Proline,1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-, (4S)-
Catalog No.: AA008NQV
75176-37-3,MFCD00865919
75176-37-3 | L-Proline,1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-, (4S)-
Pack Size: 1mg
Purity: ≥95%
in stock
$286.00 $200.00
Pack Size: 5mg
Purity: ≥95%
in stock
$1,126.00 $788.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008NQV
Chemical Name: L-Proline,1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-4-(phenylthio)-, (4S)-
CAS Number: 75176-37-3
Molecular Formula: C15H19NO3S2
Molecular Weight: 325.4463
MDL Number: MFCD00865919
SMILES: SC[C@@H](C(=O)N1C[C@H](C[C@H]1C(=O)O)Sc1ccccc1)C
Properties
Complexity: 385  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 3  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 21  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 5  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.6  
Literature fold

Title: Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of zofenopril and its active metabolite zofenoprilat in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis20110601

Title: Effects of zofenopril and ramipril on cough reflex responses in anesthetized and awake rabbits.

Journal: Journal of cardiovascular pharmacology and therapeutics20101201

Title: Effects of antihypertensive drugs on alcohol-induced functional responses of cultured human endothelial cells.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension20080201

Title: Fibroblast growth factor-2 mediates Angiotensin-converting enzyme inhibitor-induced angiogenesis in coronary endothelium.

Journal: The Journal of pharmacology and experimental therapeutics20061101

Title: Metal ion substitution in the catalytic site greatly affects the binding of sulfhydryl-containing compounds to leucyl aminopeptidase.

Journal: Biochemistry20060314

Title: The direct effects of the angiotensin-converting enzyme inhibitors, zofenoprilat and enalaprilat, on isolated human pancreatic islets.

Journal: European journal of endocrinology20060201

Title: Hydrochlorothiazide increases plasma or tissue angiotensin-converting enzyme-inhibitor drug levels in rats with myocardial infarction: differential effects on lisinopril and zofenopril.

Journal: European journal of pharmacology20051219

Title: Zofenoprilat-glutathione mixed disulfide as a specific S-thiolating agent of bovine lens aldose reductase.

Journal: Antioxidants & redox signaling20050101

Title: 11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat.

Journal: Bioorganic & medicinal chemistry20040201

Title: Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines.

Journal: Journal of medicinal chemistry19880601

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