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75504-34-6,MFCD00869497
Catalog No.:AA005X1C

75504-34-6 | Tamoxifen-N-oxide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$55.00   $38.00
- +
5mg
≥98%
in stock  
$172.00   $120.00
- +
10mg
≥98%
in stock  
$263.00   $184.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005X1C
Chemical Name:
Tamoxifen-N-oxide
CAS Number:
75504-34-6
Molecular Formula:
C26H29NO2
Molecular Weight:
387.5140
MDL Number:
MFCD00869497
SMILES:
CC/C(=C(\c1ccccc1)/c1ccc(cc1)OCC[N+](C)(C)[O-])/c1ccccc1
Properties
Properties
 
Form:
Solid  
MP:
136-141°C  
Storage:
-20 ℃;Inert atmosphere;Light sensitive;  

Computed Properties
 
Complexity:
507  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
6.6  

Literature

Title: Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide.

Journal: Breast cancer research and treatment 20120701

Title: Tamoxifen stimulates calcium entry into human platelets.

Journal: Journal of cardiovascular pharmacology 20071001

Title: Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20051001

Title: Identification and quantification of tamoxifen and four metabolites in serum by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20050729

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