Home Other Building Blocks 75644-90-5
75644-90-5,MFCD00076707
Catalog No.:AA00G2LP

75644-90-5 | DSLET

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
in stock  
$184.00   $129.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G2LP
Chemical Name:
DSLET
CAS Number:
75644-90-5
Molecular Formula:
C33H46N6O10
Molecular Weight:
686.7525
MDL Number:
MFCD00076707
SMILES:
OC[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)[C@H](O)C)CC(C)C)Cc1ccccc1)NC(=O)[C@H](Cc1ccc(cc1)O)N
Properties
Computed Properties
 
Complexity:
1110  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
49  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
10  
Rotatable Bond Count:
19  
XLogP3:
-3  

Literature

Title: Differentiation between Aδ and C fibre evoked nociceptive reflexes by TTX resistance and opioid sensitivity in the cat.

Journal: Neuroscience research 20110301

Title: [Role of serotonin receptors in the delta-opioid immunosuppression].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20101201

Title: Multi-component signaling complexes of the delta-opioid receptor with STAT5B and G proteins.

Journal: Neuropharmacology 20100901

Title: Immune response of submissive and aggressive mice under conditions of opioid receptor activation.

Journal: Bulletin of experimental biology and medicine 20091201

Title: Quantitative conformationally sampled pharmacophore for delta opioid ligands: reevaluation of hydrophobic moieties essential for biological activity.

Journal: Journal of medicinal chemistry 20070419

Title: [Effect of opiod peptides on free radical oxidation in a bone regenerate after fracture].

Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia 20050101

Title: Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens.

Journal: Neuroscience 20050101

Title: [Antiarrhythmic and cardioprotective effect of stimulation of delta1-opiate receptors in myocardial ischemia and reperfusion].

Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia 20040101

Title: Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels.

Journal: Life sciences 20030704

Title: DSLET and ACTH(4-10) increase mitotic activity of hepatocytes and suppress antibody production.

Journal: Bulletin of experimental biology and medicine 20030501

Title: [The role of opiate receptors and ATP-dependent potassium channels of mitochondria in the formation of myocardial adaptive resistance to the arrhythmogenic effect of ischemia and reperfusion].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20030101

Title: The effect of opioid agonists of delta-class DSLET, mu-class DAMGO, kappa-class U-69593 and an opioid antagonist, naloxone, on MTT activity of NALM-1 leukemic cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021101

Title: Effect of in vivo and in vitro stimulation of delta1-opioid receptors on myocardial resistance to arrhythmogenic action of ischemia and reperfusion.

Journal: Bulletin of experimental biology and medicine 20021001

Title: [Effect of opioid peptides on the repair regeneration of the bone tissue].

Journal: Arkhiv patologii 20020101

Title: Delta opioid activation of the mitogen-activated protein kinase cascade does not require transphosphorylation of receptor tyrosine kinases.

Journal: BMC pharmacology 20020101

Title: [Opiatergic modulation of cardiac resistance to arrhythmogenic exposures].

Journal: Patologicheskaia fiziologiia i eksperimental'naia terapiia 20020101

Title: [Effect of opioid peptides on proliferation and differentiation of skeletogenic cells of rabbit bone marrow in vitro].

Journal: Tsitologiia 20020101

Title: [Role of delta opioid receptors and their ligands in the development of adaptive heart protection against arrhythmogenesis].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20011201

Title: Parallel nociceptive reflex pathways with negative and positive feedback functions to foot extensors in the cat.

Journal: The Journal of physiology 20011015

Title: [The role of mu- and delta-opiate receptors in resistance of the myocardium to free radical damage].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010501

Title: Characterization of opioid receptors modulating neurogenic contractions of circular muscle from porcine ileum and evidence that delta- and kappa-opioid receptors are coexpressed in myenteric neurons.

Journal: The Journal of pharmacology and experimental therapeutics 20010401

Title: Stimulation of mu and delta-Opiate Receptors and Tolerance of Isolated Heart to Oxidative Stress: the Role of NO-Synthase.

Journal: Biochemistry. Biokhimiia 20010401

Title: Antianalgesic action of nociceptin originating in the brain is mediated by spinal prostaglandin E(2) in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20010101

Title: Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line.

Journal: Pflugers Archiv : European journal of physiology 20000301

Title: Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.

Journal: NIDA research monograph 19980301

Title: Regulation of delta opioid receptors by delta9-tetrahydrocannabinol in NG108-15 hybrid cells.

Journal: Life sciences 19980101

Title: Acute tolerance to the excitatory effects of opioids in the rat hippocampus.

Journal: Journal of neuroscience research 19950101

Title: Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

Journal: Molecular pharmacology 19940201

Title: Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.

Journal: The Journal of pharmacology and experimental therapeutics 19931001

Title: Agonist and antagonist profiles of [D-Ala2,Glu4]deltorphin and its [Cys4]- and [Ser4]-substituted derivatives: further evidence of opioid delta receptor multiplicity.

Journal: The Journal of pharmacology and experimental therapeutics 19930501

Title: Conformationally restricted deltorphin analogues.

Journal: Journal of medicinal chemistry 19921016

Title: Involvement of multiple opiate receptors in opioid kindling.

Journal: Brain research 19900528

Title: Modulation of mu, delta and kappa opioid receptors in rat brain by metal ions and histidine.

Journal: Neuropharmacology 19900501

Title: Guanine nucleotide regulation of [125I]beta-endorphin binding to NG108-15 and SK-N-SH cell membranes: specific cation requirements.

Journal: Brain research 19890724

Title: Paradoxical analgesia produced by low doses of the opiate-antagonist naloxone is mediated by interaction at a site with characteristics of the delta opioid receptor.

Journal: The Journal of pharmacology and experimental therapeutics 19890401

Title: Involvement of the mu-opiate receptor in peripheral analgesia.

Journal: Neuroscience 19890101

Title: Development of conformationally constrained linear peptides exhibiting a high affinity and pronounced selectivity for delta opioid receptors.

Journal: Journal of medicinal chemistry 19881001

Title: Opiate-induced seizures: a study of mu and delta specific mechanisms.

Journal: Experimental neurology 19860801

Title: Receptors for opioid peptides in the guinea-pig ileum.

Journal: The Journal of pharmacology and experimental therapeutics 19851101

Title: Selective cardiovascular and neuroendocrine effects of a kappa-opioid agonist in the nucleus tractus solitarii of rats.

Journal: The Journal of physiology 19851001

Title: Opiate receptor interaction of a new analgesic drug 2-piperidinoethyl dibenzylglycolate.

Journal: Chemico-biological interactions 19850101

Title: Multiple opiate receptors in the guinea pig enteric nervous system: unmasking the copresence of receptor subtypes.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19840401

Title: A comparative study in rats of the respiratory depression and analgesia induced by mu- and delta-opioid agonists.

Journal: European journal of pharmacology 19840316

Title: Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19831001

Title: Multiple opiate binding sites in the central nervous system of the rabbit. Large predominance of a mu subtype in the cerebellum and characterization of a kappa subtype in the thalamus.

Journal: Molecular pharmacology 19830701

Title: Interaction of naloxone with mu- and delta-opioid agonists on the respiration of rats.

Journal: European journal of pharmacology 19830218

Title: Local and distal effects induced by unilateral striatal application of opiates in the absence or in the presence of naloxone on the release of dopamine in both caudate nuclei and substantiae nigrae of the cat.

Journal: Brain research 19830110

Title: Comparison of mu-, delta- and kappa-receptor binding sites through pharmacologic evaluation of p-nitrophenylalanine analogs of opioid peptides.

Journal: Life sciences 19830101

Title: Improved assays for the assessment of kappa- and delta-properties of opioid ligands.

Journal: European journal of pharmacology 19821119

Title: Opioid pharmacology in the rat hippocampal slice.

Journal: Life sciences 19821101

Title: Pharmacological characterization of opioid effects in the rat hippocampal slice.

Journal: The Journal of pharmacology and experimental therapeutics 19821101

Title: Modulation of dopamine release in rat striatal slices by delta opiate agonists.

Journal: The Journal of pharmacology and experimental therapeutics 19820801

Title: Evidence of the preferential involvement of mu receptors in analgesia using enkephalins highly selective for peripheral mu or delta receptors.

Journal: Journal of medicinal chemistry 19811001

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:75644-90-5 Molecular Formula|75644-90-5 MDL|75644-90-5 SMILES|75644-90-5 DSLET