Home Amines 7568-93-6
7568-93-6,MFCD00008137
Catalog No.:AA003G9K

7568-93-6 | Phenylethanolamine

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250mg
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA003G9K
Chemical Name:
Phenylethanolamine
CAS Number:
7568-93-6
Molecular Formula:
C8H11NO
Molecular Weight:
137.1790
MDL Number:
MFCD00008137
SMILES:
NCC(c1ccccc1)O
Properties
Properties
 
BP:
160 °C17 mm Hg(lit.)  
Form:
Liquid  
MP:
56-58 °C(lit.)  
Refractive Index:
1.558-1.56  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
89.3  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.1  

Literature

Title: Determination of phenylethanolamine A in animal hair, tissues and feeds by reversed phase liquid chromatography tandem mass spectrometry with QuEChERS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120701

Title: Activated plasma coagulation β-Factor XII-induced vasoconstriction in rats.

Journal: Clinical science (London, England : 1979) 20120601

Title: Study on the use of boromycin as a chiral selector in capillary electrophoresis.

Journal: Journal of chromatography. A 20120511

Title: Murine models and cell lines for the investigation of pheochromocytoma: applications for future therapies?

Journal: Endocrine pathology 20120301

Title: Alterations of blood brain barrier function in hyperammonemia: an overview.

Journal: Neurotoxicity research 20120201

Title: Role of peripheral versus spinal 5-HT(7) receptors in the modulation of pain undersensitizing conditions.

Journal: European journal of pain (London, England) 20120101

Title: Sympathetic and catecholaminergic alterations in sleep apnea with particular emphasis on children.

Journal: Frontiers in neurology 20120101

Title: An alternating GluN1-2-1-2 subunit arrangement in mature NMDA receptors.

Journal: PloS one 20120101

Title: Differential effects of Mycobacterium bovis--derived polar and apolar lipid fractions on bovine innate immune cells.

Journal: Veterinary research 20120101

Title: 1-(2-Hy-droxy-2-phenyl-eth-yl)-3-(4-meth-oxy-phen-yl)urea.

Journal: Acta crystallographica. Section E, Structure reports online 20111001

Title: Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors.

Journal: Nature 20110714

Title: Stereoselective conjugate addition reactions to phenylglycinol-derived, unsaturated oxazolopiperidone lactams.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110704

Title: Highly stereoselective double (R)-phenylglycinol-induced cyclocondensation reactions of symmetric aryl bis(oxoacids).

Journal: Organic & biomolecular chemistry 20110407

Title: A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines.

Journal: Chirality 20110401

Title: Enantioselective synthesis of alkaloids from phenylglycinol-derived lactams.

Journal: Natural product communications 20110401

Title: An (R)-specific N-methyltransferase involved in human morphine biosynthesis.

Journal: Archives of biochemistry and biophysics 20110201

Title: The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.

Journal: International journal of molecular sciences 20110101

Title: Potent inhibition of Acid ceramidase by novel B-13 analogues.

Journal: Journal of lipids 20110101

Title: Secondary hypertension: A rare cause.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects.

Journal: Oxidative medicine and cellular longevity 20110101

Title: Hypertension and other morbidities with Cushing's syndrome associated with corticosteroids: a review.

Journal: Integrated blood pressure control 20110101

Title: Role of reactive oxygen species in the neural and hormonal regulation of the PNMT gene in PC12 cells.

Journal: Oxidative medicine and cellular longevity 20110101

Title: Comparison of chiral electrophoretic separation methods for phenethylamines and application on impurity analysis.

Journal: Journal of pharmaceutical and biomedical analysis 20101215

Title: The inhibitory effect of a novel cytotoxic somatostatin analogue AN-162 on experimental glioblastoma.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20101001

Title: Ligands in PSI structures.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20101001

Title: Targeted cytotoxic somatostatin analog AN-162 inhibits growth of human colon carcinomas and increases sensitivity of doxorubicin resistant murine leukemia cells.

Journal: Cancer letters 20100801

Title: A medicinal chemist's guide to molecular interactions.

Journal: Journal of medicinal chemistry 20100722

Title: Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/experimental approach.

Journal: Mammalian genome : official journal of the International Mammalian Genome Society 20100401

Title: Synthesis and evaluation of novel phenylethanolamine derivatives containing acetanilides as potent and selective beta3-adrenergic receptor agonists.

Journal: Chemical & pharmaceutical bulletin 20100401

Title: Identification of inhibitors of Plasmodium falciparum phosphoethanolamine methyltransferase using an enzyme-coupled transmethylation assay.

Journal: BMC biochemistry 20100101

Title: Cerebral net exchange of large neutral amino acids after lipopolysaccharide infusion in healthy humans.

Journal: Critical care (London, England) 20100101

Title: Does proteolysis explain glutamine release from the septic brain?

Journal: Critical care (London, England) 20100101

Title: Intelligent chiral sensing based on supramolecular and interfacial concepts.

Journal: Sensors (Basel, Switzerland) 20100101

Title: Inhibition of human non-small cell lung cancers with a targeted cytotoxic somatostatin analog, AN-162.

Journal: Peptides 20090901

Title: Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives.

Journal: Marine drugs 20090901

Title: Synthesis of highly enantioenriched chiral alpha-aminoorganotins via diastereoselective ring opening of chiral N-(arenesulfonyl) 2-tributylstannyloxazolidines.

Journal: The Journal of organic chemistry 20090821

Title: Preclinical evaluation of properties of a new targeted cytotoxic somatostatin analog, AN-162 (AEZS-124), and its effects on tumor growth inhibition.

Journal: Anti-cancer drugs 20090801

Title: Shape of biomolecules by free jet microwave spectroscopy: 2-amino-1-phenylethanol and 2-methylamino-1-phenylethanol.

Journal: The journal of physical chemistry. A 20090709

Title: [Studies on the chemical constituents of Epimedium brevicornum].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090701

Title: Straightforward stereoselective access to cyclic peptidomimetics.

Journal: The Journal of organic chemistry 20090605

Title: Enantioselective total synthesis of the indole alkaloid 16-episilicine.

Journal: Chemical communications (Cambridge, England) 20090528

Title: Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups.

Journal: Journal of medicinal chemistry 20090423

Title: Thermodynamic functions of molecular conformations of (2-fluoro-2-phenyl-1-ethyl)ammonium ion and (2-hydroxy-2-phenyl-1-ethyl)ammonium ion as models for protonated noradrenaline and adrenaline: first-principles computational study of conformations and thermodynamic functions for the noradrenaline and adrenaline models.

Journal: The journal of physical chemistry. A 20090319

Title: Synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.

Journal: Journal of fluorescence 20090101

Title: Preparation and chiral recognition of a mono[6A-N-1-(2-hydroxy)-phenylethylimino-6A-deoxy]-beta-cyclodextrin HPLC stationary phase.

Journal: Journal of chromatographic science 20081001

Title: Neuropharmacology.

Journal: Indian journal of pharmacology 20081001

Title: An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines.

Journal: The Journal of organic chemistry 20080905

Title: Formal total synthesis of (+)-gephyrotoxin.

Journal: The Journal of organic chemistry 20080815

Title: Discovery of a novel series of benzoic acid derivatives as potent and selective human beta3 adrenergic receptor agonists with good oral bioavailability. 3. Phenylethanolaminotetraline (PEAT) skeleton containing biphenyl or biphenyl ether moiety.

Journal: Journal of medicinal chemistry 20080814

Title: Enantioseparation and impurity determination of the enantiomers of novel phenylethanolamine derivatives by high performance liquid chromatography on amylose stationary phase.

Journal: Analytica chimica acta 20080310

Title: Solvent control of optical resolution of 2-amino-1-phenylethanol using dehydroabietic acid.

Journal: Organic & biomolecular chemistry 20080207

Title: D-phenylglycinol-derived non-covalent factor Xa inhibitors: effect of non-peptidic S4 linkage elements on affinity and anticoagulant activity.

Journal: Bioorganic & medicinal chemistry letters 20071101

Title: Purification and characterization of 2-aminoacetophenone reductase of newly isolated Burkholderia sp. YT.

Journal: Journal of bioscience and bioengineering 20071101

Title: The effect of solvation on biomolecular conformation: 2-amino-1-phenylethanol.

Journal: The journal of physical chemistry. B 20070823

Title: Enantioselective synthesis of 3,3-disubstituted piperidine derivatives by enolate dialkylation of phenylglycinol-derived oxazolopiperidone lactams.

Journal: The Journal of organic chemistry 20070608

Title: Enantioseparation of phenylglycinol in chiral-modified zeolite HY: a molecular simulation study.

Journal: Chirality 20070601

Title: Infrared spectroscopy and structure of photochemically protonated biomolecules in the gas phase: a noradrenaline analogue, lysine and alanyl alanine.

Journal: Physical chemistry chemical physics : PCCP 20070528

Title: Syntheses and anti-cancer activities of 2-[1-(indol-3-yl-/pyrimidin-5-yl-/pyridine-2-yl-/quinolin-2-yl)-but-3-enylamino]-2-phenyl-ethanols.

Journal: Bioorganic & medicinal chemistry 20070315

Title: Chiral separation of amino-alcohols using extractant impregnated resins.

Journal: Journal of chromatography. A 20070216

Title: Blockade of catecholamine-induced growth by adrenergic and dopaminergic receptor antagonists in Escherichia coli O157:H7, Salmonella enterica and Yersinia enterocolitica.

Journal: BMC microbiology 20070101

Title: Recent advances in identification and characterization of beta-adrenoceptor agonists and antagonists.

Journal: Current topics in medicinal chemistry 20070101

Title: Transcriptional regulation of human eosinophil RNases by an evolutionary- conserved sequence motif in primate genome.

Journal: BMC molecular biology 20070101

Title: Structure-selective recognition by voltammetry: enantiomeric determination of amines using azophenolic crowns in aprotic solvent.

Journal: Analytical chemistry 20061101

Title: Dynamic kinetic resolution and desymmetrization processes: a straightforward methodology for the enantioselective synthesis of piperidines.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20061016

Title: Polymer-coated hollow fiber microextraction combined with on-column stacking in capillary electrophoresis.

Journal: Journal of chromatography. A 20060922

Title: Alkylation of phenylglycinol-derived oxazolopiperidone lactams. Enantioselective synthesis of beta-substituted piperidines.

Journal: The Journal of organic chemistry 20060512

Title: Quantum simulation of a hydrated noradrenaline analog with the torsional path integral method.

Journal: The journal of physical chemistry. A 20060119

Title: Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase.

Journal: Journal of medicinal chemistry 20051117

Title: Functionalized pyrrolidines inhibit alpha-mannosidase activity and growth of human glioblastoma and melanoma cells.

Journal: Journal of medicinal chemistry 20050630

Title: Indium-mediated asymmetric Barbier-type allylation of aldimines in alcoholic solvents: synthesis of optically active homoallylic amines.

Journal: The Journal of organic chemistry 20050429

Title: 3-[(2R)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a potent and orally active antagonist of the human gonadotropin-releasing hormone receptor. Design, synthesis, and in vitro and in vivo characterization.

Journal: Journal of medicinal chemistry 20050224

Title: Comparison of the binding affinity of some newly synthesized phenylethanolamine and phenoxypropanolamine compounds at recombinant human beta- and alpha1-adrenoceptor subtypes.

Journal: The Journal of pharmacy and pharmacology 20050101

Title: Conjugate additions to phenylglycinol-derived unsaturated delta-lactams. Enantioselective synthesis of uleine alkaloids.

Journal: The Journal of organic chemistry 20041210

Title: Transformation of 2-aminoacetophenone to ( S) -2-amino-1-phenylethanol by Arthrobacter sulfureus.

Journal: Biotechnology letters 20040801

Title: Brain amino acid abnormalities in kidney disease and diabetes mellitus.

Journal: Forensic science international 20040610

Title: MMA/MPEOMA/VSA copolymer as a novel blood-compatible material: ex vivo platelet adhesion study.

Journal: Journal of materials science. Materials in medicine 20040201

Title: Highly enantioselective ruthenium-catalyzed reduction of ketones employing readily available Peptide ligands.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040105

Title: Thermodynamically controlled synthesis of amide bonds catalyzed by highly organic solvent-resistant penicillin acylase derivatives.

Journal: Biotechnology progress 20040101

Title: Chiral bis(amino alcohol)oxalamide gelators-gelation properties and supramolecular organization: racemate versus pure enantiomer gelation.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20031121

Title: Fluorescence sensing of ammonium and organoammonium ions with tripodal oxazoline receptors.

Journal: Organic letters 20030501

Title: Absence of binding of targeted analogs of somatostatin carrying cytotoxic radicals or radionuclides to growth hormone secretagogue receptors on human myocardium.

Journal: Life sciences 20030425

Title: Combination of liquid-phase microextraction and on-column stacking for trace analysis of amino alcohols by capillary electrophoresis.

Journal: Journal of chromatography. A 20021206

Title: Limited potentiation of blood pressure response to oral tyramine by brain-selective monoamine oxidase A-B inhibitor, TV-3326 in conscious rabbits.

Journal: Neuropharmacology 20021101

Title: Structure-activity relationship studies of phenoxypropanolamine derivatives for beta 3-adrenergic activity.

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101

Title: Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay.

Journal: Biochemistry 20020122

Title: Tuning and enhancing enantioselective quenching of calixarene hosts by chiral guest amines.

Journal: Analytical chemistry 20020101

Title: The enigma of conditioned taste aversion learning: stimulus properties of 2-phenylethylamine derivatives.

Journal: Physiological research 20020101

Title: Unprecedented oxidation of a phenylglycinol-derived 2-pyridone: enantioselective synthesis of polyhydroxypiperidines.

Journal: Organic letters 20011018

Title: [Isolation and fermentation conditions of strains producing 1-phenyl-2-amino-ethanol alcohol dehydrogenase].

Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20011001

Title: Enantioselective molecular sensing of aromatic amines using tetra-(S)-di-2-naphthylprolinol calix[4]arene.

Journal: The Analyst 20010701

Title: [Studies on asymmetric synthesis of R-phenylethanolamine by whole cells of Arachnia sp. P163].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20010701

Title: Activity of N-(phenethyl)phenylethanolamines at beta(1) and beta(2) adrenoceptors: structural modifications can result in selectivity for either subtype.

Journal: Pharmacology 20010201

Title: Depression during methadone withdrawal: no role for beta-phenylethylamine.

Journal: Drug and alcohol dependence 19840101

Title: [Clonidine for the treatment of heroin withdrawal syndrome].

Journal: Wiener klinische Wochenschrift 19830826

Title: Melandri S, et al. Shape of biomolecules by free jet microwave spectroscopy: 2-amino-1-phenylethanol and 2-methylamino-1-phenylethanol. J Phys Chem A. 2009 Jul 9;113(27):7769-73.

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Tags:7568-93-6 Molecular Formula|7568-93-6 MDL|7568-93-6 SMILES|7568-93-6 Phenylethanolamine