Home Other Building Blocks 760981-83-7
760981-83-7,MFCD28411434
Catalog No.:AA00G3OT

760981-83-7 | Solithromycin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$49.00   $34.00
- +
10mg
≥98%
in stock  
$93.00   $65.00
- +
25mg
≥98%
in stock  
$182.00   $127.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3OT
Chemical Name:
Solithromycin
CAS Number:
760981-83-7
Molecular Formula:
C43H65FN6O10
Molecular Weight:
845.0088
MDL Number:
MFCD28411434
SMILES:
CC[C@H]1OC(=O)[C@@](C)(F)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](C(=O)[C@@H]([C@@H]2[C@]1(C)OC(=O)N2CCCCn1nnc(c1)c1cccc(c1)N)C)C)(C)OC
Properties
Computed Properties
 
Complexity:
1530  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
13  
Heavy Atom Count:
60  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  
XLogP3:
4.3  

Literature

Title: Managing community acquired pneumonia in the elderly - the next generation of pharmacotherapy on the horizon.

Journal: Expert opinion on pharmacotherapy 20170801

Title: Antimicrobial characterisation of solithromycin (CEM-101), a novel fluoroketolide: activity against staphylococci and enterococci.

Journal: International journal of antimicrobial agents 20110101

Title: The in vitro evaluation of solithromycin (CEM-101) against pathogens isolated in the United States and Europe (2009).

Journal: The Journal of infection 20101201

Title: Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis.

Journal: Antimicrobial agents and chemotherapy 20101201

Title: Antimicrobial characterisation of CEM-101 activity against respiratory tract pathogens, including multidrug-resistant pneumococcal serogroup 19A isolates.

Journal: International journal of antimicrobial agents 20100601

Title: CEM-101, a novel fluoroketolide: antimicrobial activity against a diverse collection of Gram-positive and Gram-negative bacteria.

Journal: Diagnostic microbiology and infectious disease 20100401

Title: In vitro activity of CEM-101 against Streptococcus pneumoniae and Streptococcus pyogenes with defined macrolide resistance mechanisms.

Journal: Antimicrobial agents and chemotherapy 20100101

Title: Clinical efficacy of ketolides in the treatment of respiratory tract infections.

Journal: The Journal of antimicrobial chemotherapy 20040601

Title: Replacement therapy in patients with hereditary antithrombin III deficiency.

Journal: Seminars in hematology 19910101

Title: Rodgers W, et al. Solithromycin inhibition of protein synthesis and ribosome biogenesis in Staphylococcus aureus,Streptococcus pneumoniae, and Haemophilus influenzae. Antimicrob Agents Chemother. 2013 Apr;57(4):1632-1637.

Title: Kobayashi Y, et al. A novel macrolide solithromycin exerts superior anti-inflammatory effect via NF-κB inhibition. J Pharmacol Exp Ther. 2013 Apr;345(1):76-84.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 760981-83-7
Tags:760981-83-7 Molecular Formula|760981-83-7 MDL|760981-83-7 SMILES|760981-83-7 Solithromycin