Home Amines 764-52-3
764-52-3,MFCD07636752
Catalog No.:AA00G30T

764-52-3 | (S)-2-Amino-4-((trifluoromethyl)thio)butanoic acid

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100mg
97%
2 weeks  
$1,700.00   $1,190.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G30T
Chemical Name:
(S)-2-Amino-4-((trifluoromethyl)thio)butanoic acid
CAS Number:
764-52-3
Molecular Formula:
C5H8F3NO2S
Molecular Weight:
203.1827
MDL Number:
MFCD07636752
SMILES:
OC(=O)[C@H](CCSC(F)(F)F)N
Properties
Computed Properties
 
Complexity:
161  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
-0.7  

Literature

Title: Proteomic analysis of the cyst stage of Entamoeba histolytica.

Journal: PLoS neglected tropical diseases 20120501

Title: Transcriptional and functional analysis of trifluoromethionine resistance in Entamoeba histolytica.

Journal: The Journal of antimicrobial chemotherapy 20120201

Title: Mechanistic studies on the enzymatic processing of fluorinated methionine analogues by Trichomonas vaginalis methionine γ-lyase.

Journal: The Biochemical journal 20110915

Title: Mechanism of trifluoromethionine resistance in Entamoeba histolytica.

Journal: The Journal of antimicrobial chemotherapy 20110901

Title: Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica.

Journal: BMC genomics 20110101

Title: A highly active DNA polymerase with a fluorous core.

Journal: Angewandte Chemie (International ed. in English) 20100208

Title: Cytotoxic effect of amide derivatives of trifluoromethionine against the enteric protozoan parasite Entamoeba histolytica.

Journal: International journal of antimicrobial agents 20100101

Title: Methionine gamma-lyase: the unique reaction mechanism, physiological roles, and therapeutic applications against infectious diseases and cancers.

Journal: IUBMB life 20091101

Title: Porphyromonas gingivalis mutant defective in a putative extracytoplasmic function sigma factor shows a mutator phenotype.

Journal: Oral microbiology and immunology 20091001

Title: Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis.

Journal: The FEBS journal 20080201

Title: Reduction potential tuning of the blue copper center in Pseudomonas aeruginosa azurin by the axial methionine as probed by unnatural amino acids.

Journal: Journal of the American Chemical Society 20061213

Title: Nonnatural amino acid incorporation into the methionine 214 position of the metzincin Pseudomonas aeruginosa alkaline protease.

Journal: BMC biochemistry 20050101

Title: Efforts towards the design of 'teflon' proteins: in vivo translation with trifluorinated leucine and methionine analogues.

Journal: Chemistry & biodiversity 20041001

Title: Identification and characterization of two isoenzymes of methionine gamma-lyase from Entamoeba histolytica: a key enzyme of sulfur-amino acid degradation in an anaerobic parasitic protist that lacks forward and reverse trans-sulfuration pathways.

Journal: The Journal of biological chemistry 20031024

Title: L-Methionine-gamma-lyase, as a target to inhibit malodorous bacterial growth by trifluoromethionine.

Journal: Biochemical and biophysical research communications 20020412

Title: Elucidation of solvent exposure, side-chain reactivity, and steric demands of the trifluoromethionine residue in a recombinant protein.

Journal: Biochemistry 20011106

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