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76924-95-3,MFCD00171363
Catalog No.:AA005G1D

76924-95-3 | 8-(Ethylthio)-1H-purine-2,6(3H,7H)-dione

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5mg
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$92.00   $64.00
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10mg
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$111.00   $78.00
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25mg
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$144.00   $101.00
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50mg
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500mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005G1D
Chemical Name:
8-(Ethylthio)-1H-purine-2,6(3H,7H)-dione
CAS Number:
76924-95-3
Molecular Formula:
C7H8N4O2S
Molecular Weight:
212.2290
MDL Number:
MFCD00171363
SMILES:
CCSc1nc2c([nH]1)c(=O)[nH]c(=O)[nH]2
Properties
Computed Properties
 
Complexity:
275  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.9  

Literature

Title: Response of leaf-associated bacterial communities to primary acyl-homoserine lactone in the tobacco phyllosphere.

Journal: Research in microbiology 20120201

Title: Two G-protein-coupled-receptor candidates, Cand2 and Cand7, are involved in Arabidopsis root growth mediated by the bacterial quorum-sensing signals N-acyl-homoserine lactones.

Journal: Biochemical and biophysical research communications 20120120

Title: Characterization of an inducible promoter in different DNA copy number conditions.

Journal: BMC bioinformatics 20120101

Title: Quorum sensing signaling molecules produced by reference and emerging soft-rot bacteria (Dickeya and Pectobacterium spp.).

Journal: PloS one 20120101

Title: Quorum-sensing autoinducer molecules produced by members of a multispecies biofilm promote horizontal gene transfer to Vibrio cholerae.

Journal: FEMS microbiology letters 20110901

Title: Expression and characterization of cell-signalling molecules in Campylobacter jejuni.

Journal: Journal of applied microbiology 20110301

Title: A sensitive fluorescence reporter for monitoring quorum sensing regulated protease production in Vibrio harveyi.

Journal: Journal of microbiological methods 20110201

Title: Custom synthesis of autoinducers and their analogues.

Journal: Methods in molecular biology (Clifton, N.J.) 20110101

Title: Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism.

Journal: Molecular microbiology 20110101

Title: Microbial linguistics: perspectives and applications of microbial cell-to-cell communication.

Journal: BMB reports 20110101

Title: [Proteolytic control of expression of Vibrio fischeri lux-operon genes in Escherichia coli cells].

Journal: Genetika 20100801

Title: Establishing a quantitative definition of quorum sensing provides insight into the information content of the autoinducer signals in Vibrio harveyi and Escherichia coli.

Journal: Biochemistry 20100713

Title: Attenuation of Vibrio fischeri quorum sensing using rationally designed polymers.

Journal: Biomacromolecules 20100412

Title: Acyl-homoserine lactone-mediated cross talk among epiphytic bacteria modulates behavior of Pseudomonas syringae on leaves.

Journal: The ISME journal 20090701

Title: Identification of hydroxyl radical oxidation products of N-hexanoyl-homoserine lactone by reversed-phase high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20090401

Title: Quantifying the integration of quorum-sensing signals with single-cell resolution.

Journal: PLoS biology 20090301

Title: [Expression of N-acyl-homoserine lactonase AiiA gene affects properties of rhizospheric strain Pseudomonas chlororaphis 449].

Journal: Genetika 20090101

Title: The crystal structure of the Escherichia coli autoinducer-2 processing protein LsrF.

Journal: PloS one 20090101

Title: Directed evolution of LuxI for enhanced OHHL production.

Journal: Biotechnology and bioengineering 20081001

Title: Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi.

Journal: Cell 20080808

Title: Inter-kingdom signalling: communication between bacteria and their hosts.

Journal: Nature reviews. Microbiology 20080201

Title: Robust and sensitive control of a quorum-sensing circuit by two interlocked feedback loops.

Journal: Molecular systems biology 20080101

Title: The cyclic AMP receptor protein modulates quorum sensing, motility and multiple genes that affect intestinal colonization in Vibrio cholerae.

Journal: Microbiology (Reading, England) 20070901

Title: Making bacteria behave: new agonists and antagonists of quorum sensing.

Journal: ACS chemical biology 20070522

Title: Occurrence of N-acyl-L-homoserine lactones in extracts of some Gram-negative bacteria evaluated by gas chromatography-mass spectrometry.

Journal: Analytical biochemistry 20070215

Title: Direct quantification of N-(3-oxo-hexanoyl)-L-homoserine lactone in culture supernatant using a whole-cell bioreporter.

Journal: Journal of microbiological methods 20070101

Title: AI-1 influences the kinase activity but not the phosphatase activity of LuxN of Vibrio harveyi.

Journal: The Journal of biological chemistry 20060825

Title: Identification of the central quorum sensing regulator of virulence in the enteric phytopathogen, Erwinia carotovora: the VirR repressor.

Journal: Molecular microbiology 20060101

Title: Evidence for quorum sensing in Clostridium botulinum 56A.

Journal: Letters in applied microbiology 20060101

Title: Quorum sensing: the many languages of bacteria.

Journal: FEMS microbiology letters 20060101

Title: Alleviation of insulitis and moderation of diabetes in NOD mice following treatment with a synthetic Pseudomonas aeruginosa signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone.

Journal: Acta diabetologica 20051001

Title: N-Sulfonyl homoserine lactones as antagonists of bacterial quorum sensing.

Journal: Bioorganic & medicinal chemistry letters 20041018

Title: Regulation of AHL production and its contribution to epiphytic fitness in Pseudomonas syringae.

Journal: Molecular plant-microbe interactions : MPMI 20040501

Title: Cell-to-cell communication in bacteria: a chemical discourse.

Journal: Harvey lectures 20040101

Title: Involvement of region 4 of the sigma70 subunit of RNA polymerase in transcriptional activation of the lux operon during quorum sensing.

Journal: FEMS microbiology letters 20031121

Title: Interspecies communication in bacteria.

Journal: The Journal of clinical investigation 20031101

Title: Side-chain-to-tail thiolactone peptide inhibitors of the staphylococcal quorum-sensing system.

Journal: Bioorganic & medicinal chemistry letters 20030804

Title: [Quorum sensing in Pseudomonas aeruginosa: cell to-cell communication to sense the cell density of the same species].

Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20030801

Title: Vibrio harveyi quorum sensing: a coincidence detector for two autoinducers controls gene expression.

Journal: The EMBO journal 20030217

Title: Cell-to-cell communication across the prokaryote-eukaryote boundary.

Journal: Science (New York, N.Y.) 20021108

Title: Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae.

Journal: Cell 20020809

Title: New synthetic analogues of N-acyl homoserine lactones as agonists or antagonists of transcriptional regulators involved in bacterial quorum sensing.

Journal: Bioorganic & medicinal chemistry letters 20020422

Title: Detection, purification and characterisation of quorum-sensing signal molecules in plant-associated bacteria.

Journal: Journal of biotechnology 20011004

Title: Transgenic plants producing the bacterial pheromone N-acyl-homoserine lactone exhibit enhanced resistance to the bacterial phytopathogen Erwinia carotovora.

Journal: Molecular plant-microbe interactions : MPMI 20010901

Title: The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule.

Journal: Molecular microbiology 20010701

Title: Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase.

Journal: Nature 20010614

Title: Methods for detecting acylated homoserine lactones produced by Gram-negative bacteria and their application in studies of AHL-production kinetics.

Journal: Journal of microbiological methods 20010401

Title: Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators.

Journal: Annual review of microbiology 19960101

Title: Li SZ, et al. Influence of the d/l configuration of N-acyl-homoserine lactones (AHLs) and analogues on their Lux-R dependent quorum sensing activity. Bioorg Chem. 2018 Apr;77:215-222.

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