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7694-45-3,MFCD02114258
Catalog No.:AA005RP6

7694-45-3 | 1-Cyclohexene-1-carboxylicacid, 4-(1-methylethenyl)-

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  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005RP6
Chemical Name:
1-Cyclohexene-1-carboxylicacid, 4-(1-methylethenyl)-
CAS Number:
7694-45-3
Molecular Formula:
C10H14O2
Molecular Weight:
166.2170
MDL Number:
MFCD02114258
SMILES:
CC(=C)C1CCC(=CC1)C(=O)O
NSC Number:
641067
Properties
Computed Properties
 
Complexity:
238  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.7  

Literature

Title: Influence of the active compounds of Perilla frutescens leaves on lipid membranes.

Journal: Journal of natural products 20120224

Title: Terpinen-4-ol Induces Apoptosis in Human Nonsmall Cell Lung Cancer In Vitro and In Vivo.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.

Journal: Journal of oncology 20120101

Title: Inhibition of tumor progression by naturally occurring terpenoids.

Journal: Pharmaceutical biology 20111001

Title: Biotransformation of myrcene by Pseudomonas aeruginosa.

Journal: Chemistry Central journal 20110101

Title: Interaction of salicylate and a terpenoid plant extract with model membranes: reconciling experiments and simulations.

Journal: Biophysical journal 20101215

Title: 6-Nitro-2-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3-dione, a potent antitumor agent, induces cell cycle arrest and apoptosis.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Protective role of perillic acid against radiation-induced oxidative stress, cytokine profile, DNA damage, and intestinal toxicity in mice.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20100101

Title: Rosuvastatin induces delayed preconditioning against oxygen-glucose deprivation in cultured cortical neurons.

Journal: American journal of physiology. Cell physiology 20090101

Title: GO Explorer: A gene-ontology tool to aid in the interpretation of shotgun proteomics data.

Journal: Proteome science 20090101

Title: Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.

Journal: Cancer letters 20071118

Title: Activation of calcium-dependent kinases and epidermal growth factor receptor regulate muscarinic acetylcholine receptor-mediated MAPK/ERK activation in thyroid epithelial cells.

Journal: Cellular signalling 20071001

Title: The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases.

Journal: Immunity & ageing : I & A 20070101

Title: Modulatory effect of interleukin-1beta on rat isolated basilar artery contraction.

Journal: European journal of pharmacology 20060215

Title: P2Y receptors activate MAPK/ERK through a pathway involving PI3K/PDK1/PKC-zeta in human vein endothelial cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

Title: Effect of D-limonene on immune response in BALB/c mice with lymphoma.

Journal: International immunopharmacology 20050501

Title: A novel psychrotrophic fungus, Mortierella minutissima, for D-limonene biotransformation.

Journal: Biotechnology letters 20050201

Title: A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days.

Journal: Cancer chemotherapy and pharmacology 20041001

Title: Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro.

Journal: Anticancer research 20040101

Title: Farnesyl transferase inhibitors enhance death receptor signals and induce apoptosis in multiple myeloma cells.

Journal: Leukemia & lymphoma 20031201

Title: Effect of naturally occurring monoterpenes carvone, limonene and perillic acid in the inhibition of experimental lung metastasis induced by B16F-10 melanoma cells.

Journal: Journal of experimental & clinical cancer research : CR 20030901

Title: Pharmacological modulation of fatty acid desaturation and of cholesterol biosynthesis in THP-1 cells.

Journal: Lipids 20030801

Title: Monoterpene regulation of Ras and Ras-related protein expression.

Journal: Journal of lipid research 20030601

Title: A phase I trial of perillyl alcohol in patients with advanced solid tumors.

Journal: Cancer chemotherapy and pharmacology 20030601

Title: Biotransformation of limonene by bacteria, fungi, yeasts, and plants.

Journal: Applied microbiology and biotechnology 20030501

Title: Immunomodulatory activity of naturally occurring monoterpenes carvone, limonene, and perillic acid.

Journal: Immunopharmacology and immunotoxicology 20030501

Title: Fluvastatin induces apoptosis in rat neonatal cardiac myocytes: a possible mechanism of statin-attenuated cardiac hypertrophy.

Journal: Journal of cardiovascular pharmacology 20021201

Title: Pharmacokinetics of perillic acid in humans after a single dose administration of a citrus preparation rich in d-limonene content.

Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021101

Title: Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.

Journal: Cancer letters 20020726

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Role of mitogen-activated protein kinase pathway in acetylcholine-mediated in vitro relaxation of rat pulmonary artery.

Journal: European journal of pharmacology 20020102

Title: Phase I study of perillyl alcohol in patients with refractory malignancies.

Journal: Cancer biology & therapy 20020101

Title: Effect of S(-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation.

Journal: Biochemical pharmacology 20011215

Title: Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens.

Journal: Experimental eye research 20010801

Title: Bioconversion of limonene to increased concentrations of perillic acid by Pseudomonas putida GS1 in a fed-batch reactor.

Journal: Applied microbiology and biotechnology 20010701

Title: Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds.

Journal: Research in virology 19970101

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Tags:7694-45-3 Molecular Formula|7694-45-3 MDL|7694-45-3 SMILES|7694-45-3 1-Cyclohexene-1-carboxylicacid, 4-(1-methylethenyl)-