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7759-35-5,MFCD01711303
Catalog No.:AA00G29H

7759-35-5 | Nestoron

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5mg
≥95%
in stock  
$63.00   $44.00
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10mg
≥95%
in stock  
$112.00   $78.00
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25mg
≥95%
in stock  
$262.00   $183.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G29H
Chemical Name:
Nestoron
CAS Number:
7759-35-5
Molecular Formula:
C23H30O4
Molecular Weight:
370.4819
MDL Number:
MFCD01711303
SMILES:
CC(=O)O[C@]1(C(=O)C)C(=C)C[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2=CC(=O)CC[C@H]12
Properties
Computed Properties
 
Complexity:
762  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
3  
XLogP3:
2.9  

Literature

Title: Increased impact of a contraceptive vaginal ring with ethinyl estradiol and nestorone on C-reactive protein.

Journal: Steroids 20121101

Title: A new combination of testosterone and nestorone transdermal gels for male hormonal contraception.

Journal: The Journal of clinical endocrinology and metabolism 20121001

Title: Discriminant analysis of the metabolic effects of a new combined contraceptive vaginal ring containing Nestorone/EE vs. a second-generation oral contraceptive containing levonorgestrel/EE.

Journal: Contraception 20120901

Title: Progesterone receptors: a key for neuroprotection in experimental stroke.

Journal: Endocrinology 20120801

Title: Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors.

Journal: Endocrinology 20111001

Title: Relative progestational and androgenic activity of four progestins used for male hormonal contraception assessed in vitro in relation to their ability to suppress LH secretion in the castrate male rat.

Journal: Molecular and cellular endocrinology 20101026

Title: Central modifications of allopregnanolone and beta-endorphin following subcutaneous administration of Nestorone.

Journal: The Journal of steroid biochemistry and molecular biology 20090801

Title: Combined transdermal testosterone gel and the progestin nestorone suppresses serum gonadotropins in men.

Journal: The Journal of clinical endocrinology and metabolism 20090701

Title: Comparative actions of progesterone, medroxyprogesterone acetate, drospirenone and nestorone on breast cancer cell migration and invasion.

Journal: BMC cancer 20080101

Title: Comparison of the impact of vaginal and oral administration of combined hormonal contraceptives on hepatic proteins sensitive to estrogen.

Journal: Contraception 20070601

Title: Comparative effects of a contraceptive vaginal ring delivering a nonandrogenic progestin and continuous ethinyl estradiol and a combined oral contraceptive containing levonorgestrel on hemostasis variables.

Journal: American journal of obstetrics and gynecology 20060701

Title: New progestagens for contraceptive use.

Journal: Human reproduction update 20060101

Title: Feasibility study of Nestorone-ethinylestradiol vaginal contraceptive ring for emergency contraception.

Journal: Contraception 20060101

Title: Serum Nestorone and ethinyl estradiol levels, and ovulation inhibition in women using three different dosage combinations of a Nestorone progestogen-ethinyl estradiol contraceptive vaginal ring on a bleeding-signaled regimen.

Journal: Contraception 20050701

Title: Clinical performance and menstrual bleeding patterns with three dosage combinations of a Nestorone progestogen/ethinyl estradiol contraceptive vaginal ring used on a bleeding-signaled regimen.

Journal: Contraception 20050701

Title: Contraceptive vaginal rings releasing Nestorone and ethinylestradiol: a 1-year dose-finding trial.

Journal: Contraception 20050201

Title: The effect of Nestorone on gonadotropic cells in pituitary of rats.

Journal: Contraception 20040601

Title: Nestorone: clinical applications for contraception and HRT.

Journal: Steroids 20031101

Title: Enlarged ovarian follicles in users of a levonorgestrel-releasing intrauterine system and contraceptive implant.

Journal: The Journal of reproductive medicine 20030801

Title: Steroidal contraceptive vaginal rings.

Journal: International journal of clinical practice 20030601

Title: Subdermal progestin implant (Nestorone) in the treatment of endometriosis: clinical response to various doses.

Journal: Acta obstetricia et gynecologica Scandinavica 20030201

Title: Recent developments in contraceptive implants at the Population Council.

Journal: Contraception 20020101

Title: Implant contraception.

Journal: Seminars in reproductive medicine 20011201

Title: Contraceptive vaginal rings.

Journal: Seminars in reproductive medicine 20011201

Title: Ovarian function during use of vaginal rings delivering three different doses of Nestorone.

Journal: Contraception 20010501

Title: Prasad PV, et al. Single-dose pharmacokinetics of Nestorone, a potential female-contraceptive.Steroids. 2010 Mar;75(3):252-64. Epub 2010 Jan 11.

Title: Hussain R, et al. Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors. Endocrinology. 2011 Oct;152(10):3820-31.

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Tags:7759-35-5 Molecular Formula|7759-35-5 MDL|7759-35-5 SMILES|7759-35-5 Nestoron