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Title: Novel protocol for the chemical synthesis of crustacean hyperglycemic hormone analogues--an efficient experimental tool for studying their functions.
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Title: Tight binding of transition-state analogues to a peptidyl-aminoacyl-L/D-isomerase from frog skin.
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Title: The influence of the stereochemistry of alanine residue on the solid state conformation and crystal packing of opioid peptides containing D-Ala or L-Ala in message domain--XRD and NMR study.
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Title: Emerging knowledge of regulatory roles of D-amino acids in bacteria.
Journal: Cellular and molecular life sciences : CMLS 20110301
Title: Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine.
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Title: Involvement of mouse μ-opioid receptor splice variants in the spinal antinociception induced by the dermorphin tetrapeptide analog amidino-TAPA.
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Title: Ligand-directed functional selectivity at the mu opioid receptor revealed by label-free integrative pharmacology on-target.
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Title: AntiBP2: improved version of antibacterial peptide prediction.
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Title: Discovery of dermorphin-based affinity labels with subnanomolar affinity for mu opioid receptors.
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Title: Evaluation of side effects through selective ablation of the mu opioid receptor expressing descending nociceptive facilitatory neurons in the rostral ventromedial medulla with dermorphin-saporin.
Journal: Neurotoxicology 20091101
Title: Synthesis and receptor binding of opioid peptide analogues containing beta3-homo-amino acids.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20091101
Title: Partial ablation of mu-opioid receptor rich striosomes produces deficits on a motor-skill learning task.
Journal: Neuroscience 20090929
Title: Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2.
Journal: The Journal of biological chemistry 20090925
Title: Protective effect of dermorphin analogue sedatin on indomethacin-induced injury to the gastric mucosa.
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Title: D-amino acid detection in peptides by MALDI-TOF-TOF.
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Title: Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors.
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Title: Conformation-activity relationships of cyclo-constrained micro/delta opioid agonists derived from the N-terminal tetrapeptide segment of dermorphin/deltorphin.
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Title: Amygdala intercalated neurons are required for expression of fear extinction.
Journal: Nature 20080731
Title: Blood-brain barrier penetration by two dermorphin tetrapeptide analogues: role of lipophilicity vs structural flexibility.
Journal: Journal of medicinal chemistry 20080424
Title: The use of tritium-labeled dermorphin for studying the interactions of C-terminal dermorphin fragment Tyr-Pro-Ser-NH2 and its stereoisomer Tyr-D-Pro-Ser-NH2 with opioid receptors.
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Title: Multiple ligands in opioid research.
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Title: Methylnaltrexone in the treatment of opioid-induced constipation.
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Title: Effect of synthetic dermorphin analogues on tissue homeostasis in the myocardium of newborn albino rats.
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Title: Effect of sedatin (synthetic dermorphin analog) on the development of Acipenser schrenckii young fish.
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Title: Mechanisms for the effect of arginine-containing dermorphin analogue on proliferative processes in the gastric mucosa of albino rats.
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Title: Ureido group containing cyclic dermorphin(1-7) analogues: synthesis, biology and conformation.
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Title: Receptor binding properties and antinociceptive effects of chimeric peptides consisting of a micro-opioid receptor agonist and an ORL1 receptor antagonist.
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Title: Supranodose vagotomy eliminates respiratory depression evoked by dermorphin in anaesthetized rats.
Journal: European journal of pharmacology 20070601
Title: Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA.
Journal: European journal of pharmacology 20070410
Title: Novel glycosylated [Lys(7)]-dermorphin analogues: synthesis, biological activity and conformational investigations.
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Title: [Comparative analysis of analgesic activities of dermorphin, [DPro6]-dermorphin, and their C-terminal tripeptides].
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Title: [Synthesis, pharmacokinetics, and metabolism of the C-terminal tripeptide of dermorphin and its diastereomer].
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Title: Dependence of the analgesic activities of dermorphin, metenkephalin, and dynorphin A on the ambient temperature.
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Title: [The relationship between the structure of dermorphines and their thermoregulatory activity].
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Title: Effects of the intravenous administration of [Lys7]dermorphin on local cerebral glucose utilization in the rat.
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Title: Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization.
Journal: Neuroscience 20060721
Title: Involvement of spinal mu1-opioid receptors on the Tyr-d-Arg-Phe-sarcosine-induced antinociception.
Journal: European journal of pharmacology 20060701
Title: Targeted drug delivery crossing cytoplasmic membranes of intended cells via ligand-grafted sterically stabilized liposomes.
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Title: Cyclic dermorphin tetrapeptide analogues obtained via ring-closing metathesis.
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Title: Conversion of the potent delta-opioid agonist H-Dmt-Tic-NH-CH(2)-bid into delta-opioid antagonists by N(1)-benzimidazole alkylation(1).
Journal: Journal of medicinal chemistry 20051229
Title: Synthesis and biological evaluation of constrained analogues of the opioid peptide H-Tyr-D-Ala-Phe-Gly-NH2 using the 4-amino-2-benzazepin-3-one scaffold.
Journal: The journal of peptide research : official journal of the American Peptide Society 20051101
Title: Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the Guinea-pig ileum; reversal by cholecystokinin.
Journal: Neurotoxicology 20051001
Title: Distinguishing and quantifying peptides and proteins containing D-amino acids by tandem mass spectrometry.
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Title: Cyclic enkephalin and dermorphin analogues containing a carbonyl bridge.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20050601
Title: Abbreviated nomenclature for cyclic and branched homo- and hetero-detic peptides.
Journal: The journal of peptide research : official journal of the American Peptide Society 20050601
Title: 6-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid mimics active conformation of tyrosine in opioid peptides.
Journal: Bioorganic & medicinal chemistry letters 20050516
Title: New tris-alkoxycarbonyl arginine derivatives for peptide synthesis.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20050101
Title: Synthesis of dermorphin-(1-4) derivatives catalyzed by proteases in organic solvents.
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Title: [Study of thermoregulatory activity of a fragment of natural dermorphin precursor Arg-dermorphin and its analogs].
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Title: [Analgesic activity of dermorphin and its proline analogs].
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Title: [Comparative study of the antiarrhythmic activity of mu- and delta-opioid receptor agonists during acute cardiac ischemia and reperfusion models in rats].
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Title: Tolerance develops in spinal cord, but not in brain with chronic [Dmt1]DALDA treatment.
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Title: Blood-brain barrier permeability of novel [D-arg2]dermorphin (1-4) analogs: transport property is related to the slow onset of antinociceptive activity in the central nervous system.
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Title: [Thermoregulatory activity of dermorphin fragments].
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Title: Human brain cathepsin H as a neuropeptide and bradykinin metabolizing enzyme.
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Title: Synthesis, conformation and biological activity of dermorphin and deltorphin I analogues containing N-alkylglycine in place of residues in position 1, 3, 5 and 6.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20031001
Title: Potent side-chain to side-chain cyclized dermorphin analogues containing a carbonyl bridge.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20031001
Title: Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030910
Title: Opioid peptides: synthesis and biological properties of [(N gamma-glucosyl,N gamma-methoxy)-alpha, gamma-diamino-(S)-butanoyl]4-deltorphin-1-neoglycopeptide and related analogues.
Journal: Organic & biomolecular chemistry 20030907
Title: Expression of EGFP-amino-tagged human mu opioid receptor in Drosophila Schneider 2 cells: a potential expression system for large-scale production of G-protein coupled receptors.
Journal: Protein expression and purification 20030901
Title: Endogenous opioid peptides contribute to antinociceptive potency of intrathecal [Dmt1]DALDA.
Journal: The Journal of pharmacology and experimental therapeutics 20030501
Title: Dermorphin tetrapeptide analogues with 2',6'-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high mu opioid receptor binding and biological activities.
Journal: Bioorganic & medicinal chemistry letters 20030407
Title: In vitro and in vivo opioid activity of [DPro(6)]dermorphin, a new dermorphin analogue.
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Title: Dermorphin-based potential affinity labels for mu-opioid receptors.
Journal: The journal of peptide research : official journal of the American Peptide Society 20030101
Title: Vas deferens response to selective opioid receptor agonists in adult mice is impaired following postnatal repeated mild stress.
Journal: European journal of pharmacology 20030101
Title: Dmt and opioid peptides: a potent alliance.
Journal: Biopolymers 20030101
Title: Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screening.
Journal: BMC pharmacology 20030101
Title: Potent delta-opioid receptor agonists containing the Dmt-Tic pharmacophore.
Journal: Journal of medicinal chemistry 20021205
Title: The mu-selective heptapeptide opioid dermorphin has two conformations around Phe3 psi with no head-to-tail interaction. A quantitative 2-D NMR and molecular modeling analysis.
Journal: Journal of biomolecular structure & dynamics 20021201
Title: Efferent projections from the striatal patch compartment: anterograde degeneration after selective ablation of neurons expressing mu-opioid receptor in rats.
Journal: Neuroscience letters 20021025
Title: Urinary peptides in Rett syndrome.
Journal: Autism : the international journal of research and practice 20020901
Title: Lack of involvement of mu(1) opioid receptors in dermorphin-induced inhibition of hypoxic and hypercapnic ventilation in rat pups.
Journal: Respiratory physiology & neurobiology 20020801
Title: mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020701
Title: Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615
Title: mu-1 opioid receptor stimulation decreases body temperature in conscious, unrestrained neonatal rats.
Journal: Experimental biology and medicine (Maywood, N.J.) 20020601
Title: Long time dynamics of Met-enkephalin: comparison of explicit and implicit solvent models.
Journal: Biophysical journal 20020401
Title: Dermorphin and deltorphin heptapeptide analogues: replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity.
Journal: Bioorganic & medicinal chemistry letters 20020325
Title: Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties.
Journal: Journal of medicinal chemistry 20020131
Title: [Dmt(1)]DALDA is highly selective and potent at mu opioid receptors, but is not cross-tolerant with systemic morphine.
Journal: Current medicinal chemistry 20020101
Title: [Dermorphins--a natural opioids with unique primary structure that determines their biological specificity].
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Title: [Effect of dermorphin analogs on thermoregulation of rats under various thermal conditions].
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Title: [Effect of structural changes of Pro6 in dermorphin molecule on its antinociceptive activity].
Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20020101
Title: [Dependence of neuropeptide physiological effects on a route of administration].
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Title: Fetal alveolar epithelial cells contain [D-Ala(2)]-deltorphin I-like immunoreactivity: delta- and mu-opiate receptors mediate opposite effects in developing lung.
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Title: [2',6'-Dimethyltyrosine]dynorphin A(1-11)-NH2 analogues lacking an N-terminal amino group: potent and selective kappa opioid antagonists.
Journal: Journal of medicinal chemistry 20010913
Title: Modulation of breathing by mu1 and mu2 opioid receptor stimulation in neonatal and adult rats.
Journal: Respiration physiology 20010901
Title: HS-599: a novel long acting opioid analgesic does not induce place-preference in rats.
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Title: Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010715
Title: Pharmacological characterization of the dermorphin analog [Dmt(1)]DALDA, a highly potent and selective mu-opioid peptide.
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Title: Activity of mu- and delta-opioid agonists in vas deferens from mice deficient in MOR gene.
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Title: Receptor binding and biological activity of the dermorphin analog Tyr-D-Arg(2)-Phe-Sar (TAPS).
Journal: European journal of pharmacology 20010323
Title: Effects of opiate receptor ligands on DNA synthesis in tracheal epitheliocytes and smooth muscle cells of newborn albino rats.
Journal: Bulletin of experimental biology and medicine 20010201
Title: The delta-selective opioid peptide dermenkephalin and the mu-selective hybrid peptide dermenkephalin-[1-4]-dermophin-[5-7] display strikingly different conformations despite identical tetrapeptide N-termini. A quantitative 2-D NMR and molecular modeling analysis.
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Title: A new opioid peptide predicted from cloned cDNAs from skin of Pachymedusa dacnicolor and Agalychnis annae.
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Title: Opioid peptides from frog skin.
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Title: Tachykinins and other biologically active peptides from the skin of the Costa Rican phyllomedusid frog Agalychnis callidryas.
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Title: Comparative conformational analyses of mu-selective dermorphin and delta-selective deltorphin-II in aqueous solution by 1H-NMR spectroscopy.
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Title: Opioid activity of dermenkephalin analogues in the guinea-pig myenteric plexus and the hamster vas deferens.
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Title: Identification of a D-alanine-containing polypeptide precursor for the peptide opioid, dermorphin.
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Title: Differential contribution of C-terminal regions of dermorphin and dermenkephalin to opioid-sites selection and binding potency.
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