Home Amines 77883-43-3
77883-43-3,MFCD00216023
Catalog No.:AA00ICTO

77883-43-3 | 2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine; methanesulfonic acid

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1mg
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$7.00   $5.00
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100mg
98%
in stock  
$12.00   $8.00
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250mg
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$17.00   $12.00
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1g
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$34.00   $24.00
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5g
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25g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ICTO
Chemical Name:
2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine; methanesulfonic acid
CAS Number:
77883-43-3
Molecular Formula:
C24H29N5O8S
Molecular Weight:
547.5808
MDL Number:
MFCD00216023
SMILES:
CS(=O)(=O)O.COc1cc2nc(nc(c2cc1OC)N)N1CCN(CC1)C(=O)C1COc2c(O1)cccc2
NSC Number:
759284
Properties
Computed Properties
 
Complexity:
770  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route
3663-81-8    77883-43-3   
CASUnavailable 

[1]Tsyskovskaia,Irina;Kandil,Mustapha;Beaumier,Yves[SyntheticCommunications,2007,vol.37,#3,p.447-450]

[1]CurrentPatentAssignee:CIPLALTD-WO2009/81087,2009,A1Locationinpatent:Page/Pagecolumn13

[1]CurrentPatentAssignee:CIPLALTD-US2012/41199,2012,A1Locationinpatent:Page/Pagecolumn8

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Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120201

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Journal: International journal of clinical practice 20120201

Title: Orthostatic hypertension: home blood pressure monitoring for detection and assessment of treatment with doxazosin.

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Title: Effect of doxazosin on expression of eNOS in rat kidney in the presence of partial bladder outlet obstruction.

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Journal: International journal of clinical practice 20111101

Title: Effectiveness of doxazosin on erectile dysfunction in patients with lower urinary tract symptoms.

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Title: Effect of doxazosin gastrointestinal therapeutic system 4 mg vs tamsulosin 0.2 mg on nocturia in Chinese men with lower urinary tract symptoms: a prospective, multicenter, randomized, open, parallel study.

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Journal: Journal of cataract and refractive surgery 20110801

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: Hemodynamic instability during resection of pheochromocytoma in MEN versus non-MEN patients.

Journal: European journal of endocrinology 20110701

Title: Cell membrane chromatography competitive binding analysis for characterization of α1A adrenoreceptor binding interactions.

Journal: Analytical and bioanalytical chemistry 20110701

Title: An open, comparative, multicentre clinical study of combined oral therapy with sildenafil and doxazosin GITS for treating Chinese patients with erectile dysfunction and lower urinary tract symptoms secondary to benign prostatic hyperplasia.

Journal: Asian journal of andrology 20110701

Title: Comparison of effects of alpha receptor blockers on endothelial functions and coagulation parameters in patients with benign prostatic hyperplasia.

Journal: Urology 20110601

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Journal: European urology 20110501

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Journal: European urology 20110501

Title: Risk factors for intraoperative floppy iris syndrome: a meta-analysis.

Journal: Ophthalmology 20110401

Title: Effects of the chronic use of finasteride and doxazosin mesylate on the histomorphometric characteristics of the prostate: experimental study in rats.

Journal: International urology and nephrology 20110301

Title: [Series, clinical study from Japan and its reflections; Japan Morning Surge-1 (JMS-1) study].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20110210

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Journal: Urologiia (Moscow, Russia : 1999) 20110101

Title: Effects of α-blocker 'add on' treatment on blood pressure in symptomatic BPH with or without concomitant hypertension.

Journal: Prostate cancer and prostatic diseases 20101201

Title: pH-independent sustained release matrix tablet containing doxazosin mesylate: effect of citric acid.

Journal: Archives of pharmacal research 20101201

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Journal: Zhonghua nan ke xue = National journal of andrology 20101201

Title: Matrix tablets based on carrageenans with dual controlled release of doxazosin mesylate.

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Journal: Journal of medicinal chemistry 20090813

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Journal: Life sciences 20090812

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Journal: Urology 20090801

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Journal: Cardiovascular drugs and therapy 20090801

Title: Safety and efficacy of doxazosin as an 'add-on' antihypertensive therapy in mild to moderate heart failure patients.

Journal: Acta cardiologica 20090801

Title: Effects of four different alpha(1)-adrenoceptor antagonists on alpha-adrenoceptor agonist-induced contractions in isolated mouse and hamster ureters.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20090801

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Journal: Journal of hypertension 20090601

Title: Resistant hypertension. What is the best approach?

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Title: [Ejaculatory disorder caused by doxazosin administration for blood pressure control in patient with pheochomocytoma].

Journal: Hinyokika kiyo. Acta urologica Japonica 20090601

Title: The effect of doxazosin mesilate on cerebral blood flow in patients with hypertension and chronic cerebral infarction.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20090601

Title: Piperazine-designed alpha 1A/alpha 1D-adrenoceptor blocker KMUP-1 and doxazosin provide down-regulation of androgen receptor and PSA in prostatic LNCaP cells growth and specifically in xenografts.

Journal: The Prostate 20090501

Title: Transcriptome of hypertension-induced left ventricular hypertrophy and its regression by antihypertensive therapies.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20090501

Title: Combination of doxazosin and sildenafil exerts an additive relaxing effect compared with each compound alone on human cavernosal and prostatic tissue.

Journal: The journal of sexual medicine 20090301

Title: Doxazosin and heart failure: to be or not to be.

Journal: Journal of hypertension 20090201

Title: Spironolactone and doxazosin treatment in patients with resistant hypertension.

Journal: Revista espanola de cardiologia 20090201

Title: Possible difference in the sympathetic activation on extreme dippers with or without exaggerated morning surge.

Journal: Hypertension (Dallas, Tex. : 1979) 20090101

Title: Doxazosin: safety and efficacy in the treatment of resistant arterial hypertension.

Journal: Blood pressure 20090101

Title: Spectrophotometric determination of doxazosin mesylate in tablets by ion-pair and charge-transfer complexation reactions.

Journal: Journal of AOAC International 20090101

Title: Heterogeneity of morphological and functional changes in various compartments of rat urinary bladder in infravesical obstruction of the urinary tract.

Journal: Bulletin of experimental biology and medicine 20090101

Title: Effects of alpha-adrenoceptor antagonist doxazosin on MDR1-mediated multidrug resistance and transcellular transport.

Journal: Oncology research 20090101

Title: Efficacy of alpha-Adrenergic Receptor Blockers in the Treatment of Male Lower Urinary Tract Symptoms.

Journal: Reviews in urology 20090101

Title: Effect of 3 months of doxazosin therapy on T-cell subsets in type 2 diabetic patients.

Journal: The Journal of international medical research 20090101

Title: [Efficacy of combined treatment of large prostatic adenoma with doxasozine and finasteride].

Journal: Urologiia (Moscow, Russia : 1999) 20090101

Title: Heart failure with preserved and reduced left ventricular ejection fraction in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.

Journal: Circulation 20081125

Title: Current role of alpha-blockers in the treatment of benign prostatic hyperplasia.

Journal: BJU international 20081101

Title: Proteomic analysis of androgen-independent growth in low and high passage human LNCaP prostatic adenocarcinoma cells.

Journal: BMB reports 20081031

Title: Monitoring of the central pulse pressure is useful for detecting cardiac overload during antiadrenergic treatment: the Japan Morning Surge 1 study.

Journal: Journal of hypertension 20081001

Title: Release characteristics and in vitro-in vivo correlation of pulsatile pattern for a pulsatile drug delivery system activated by membrane rupture via osmotic pressure and swelling.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080901

Title: How many drugs for LUTS due to BPH are too many?

Journal: The Journal of urology 20080901

Title: Effect of vardenafil on blood pressure profile of patients with erectile dysfunction concomitantly treated with doxazosin gastrointestinal therapeutic system for benign prostatic hyperplasia.

Journal: The Journal of urology 20080901

Title: Long-term treatment with finasteride results in a clinically significant reduction in total prostate volume compared to placebo over the full range of baseline prostate sizes in men enrolled in the MTOPS trial.

Journal: The Journal of urology 20080901

Title: The use of intracameral phenylephrine in the management of intraoperative floppy-iris syndrome with doxazosin.

Journal: Eye (London, England) 20080801

Title: Orthostatic hypertension detected by self-measured home blood pressure monitoring: a new cardiovascular risk factor for elderly hypertensives.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080801

Title: Comparison of the cardiac electrophysiological effects between doxazosin and bunazosin.

Journal: Journal of biomedical science 20080701

Title: Effect of doxazosin on the left ventricular structure and function in morning hypertensive patients: the Japan Morning Surge 1 study.

Journal: Journal of hypertension 20080701

Title: Effect of doxazosin gastrointestinal therapeutic system as third-line antihypertensive therapy on blood pressure and lipids in the Anglo-Scandinavian Cardiac Outcomes Trial.

Journal: Circulation 20080701

Title: Intraoperative floppy-iris syndrome associated with systemic alpha blockers.

Journal: Journal of cataract and refractive surgery 20080701

Title: In vivo administration of doxazosin in rats highly decreases serum circulating levels of testosterone through a mechanism involving the testicular renin-angiotensin system.

Journal: International journal of andrology 20080601

Title: An alpha-adrenergic blocker titrated by self-measured blood pressure recordings lowered blood pressure and microalbuminuria in patients with morning hypertension: the Japan Morning Surge-1 Study.

Journal: Journal of hypertension 20080601

Title: [Alpha blockers in use for symptomatic benign prostatic hyperplasia--are all drugs born equal?].

Journal: Harefuah 20080601

Title: Assessment of therapeutic drug efficiency.

Journal: Bulletin of experimental biology and medicine 20080601

Title: Quantification of doxazosin in human plasma using hydrophilic interaction liquid chromatography with tandem mass spectrometry.

Journal: Journal of separation science 20080501

Title: [Medication combined with local hyperthermia: a desirable therapy for chronic prostatitis pain symptoms].

Journal: Zhonghua nan ke xue = National journal of andrology 20080501

Title: Doxazosin reduces cell proliferation and increases collagen fibers in rat prostatic lobes.

Journal: Cell and tissue research 20080401

Title: Involvement of transcription factor activator protein-2alpha in doxazosin-induced HeLa cell apoptosis.

Journal: Acta pharmacologica Sinica 20080401

Title: Endothelial alpha1-adrenoceptors regulate neo-angiogenesis.

Journal: British journal of pharmacology 20080301

Title: Doxazosin in the current treatment of hypertension.

Journal: Expert opinion on pharmacotherapy 20080301

Title: Can doxazosin inhibit the hypertension-induced changes of endocrine cells in the stomach of spontaneously hypertensive rats?

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080301

Title: Add-on therapy with a nighttime dose of doxazosin in patients with uncontrolled hypertension: effects on autonomic modulation of the cardiovascular system.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20080301

Title: alpha(1)-Adrenoceptor antagonists prevent paracetamol-induced hepatotoxicity in mice.

Journal: British journal of pharmacology 20080201

Title: Doxazosin induces apoptosis of cells expressing hERG K+ channels.

Journal: European journal of pharmacology 20080128

Title: Clinical outcomes by race in hypertensive patients with and without the metabolic syndrome: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Archives of internal medicine 20080128

Title: Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.

Journal: JAMA 20080123

Title: The influence of alpha1-antagonist on the expression pattern of TNF receptor family in primary culture of prostate epithelial cells from BPH patients.

Journal: Prostate cancer and prostatic diseases 20080101

Title: The alpha1-adrenergic receptor antagonist doxazosin inhibits EGFR and NF-kappaB signalling to induce breast cancer cell apoptosis.

Journal: European journal of cancer (Oxford, England : 1990) 20080101

Title: Comparison of the effects of doxazosin and atenolol on target organ damage in adults with type 2 diabetes mellitus and hypertension in the CARDHIAC study: a 9-month, prospective, randomized, open-label, blinded-evaluation trial.

Journal: Clinical therapeutics 20080101

Title: Treatment for chronic prostatitis/chronic pelvic pain syndrome: levofloxacin, doxazosin and their combination.

Journal: Urologia internationalis 20080101

Title: The effect of various alpha1-adrenergic receptor antagonists on pupillary dilation.

Journal: Annals of ophthalmology (Skokie, Ill.) 20080101

Title: [Clinical and neuroimmunoendocrine effects of doxasosine in treatment of arterial hypertension accompanied by prostate benign hyperplasia in elderly people].

Journal: Klinicheskaia meditsina 20080101

Title: Recurrent autonomic dysreflexia due to chronic aortic dissection in an adult male with cervical spinal cord injury.

Journal: TheScientificWorldJournal 20080101

Title: Efficacy of doxazosin in the treatment of acute urinary retention due to benign prostate hyperplasia.

Journal: Urologia internationalis 20080101

Title: [Changes in microcirculation of the urinary bladder in patients with stage II prostatic adenoma depending on the treatment method].

Journal: Urologiia (Moscow, Russia : 1999) 20080101

Title: [Clinical and neuroimmunoendocrine effects of doxasosine in treatment of benign hyperplasia of the prostate in elderly people].

Journal: Advances in gerontology = Uspekhi gerontologii 20080101

Title: Histologic influence of doxazosin and finasteride in benign prostatic hyperplasia accompanying chronic inflammation.

Journal: Urologia internationalis 20080101

Title: [Efficacy and safety of doxazosine in combination with finasteride in the treatment of prostatic adenoma].

Journal: Urologiia (Moscow, Russia : 1999) 20080101

Title: Human epididymal and prostatic tracts of vas deferens: different contraction response to noradrenaline stimulation in isolated organ bath assay.

Journal: European journal of pharmacology 20071222

Title: Add-on therapy with doxazosin in patients with hypertension influences arterial stiffness and albuterol-mediated arterial vasodilation.

Journal: British journal of clinical pharmacology 20071201

Title: Novel quinazoline-based compounds impair prostate tumorigenesis by targeting tumor vascularity.

Journal: Cancer research 20071201

Title: [Efficacy of monotherapy with 15 antihypertensive agents in treating essential hypertension assessed by 24-hour ambulatory blood pressure monitoring].

Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20071201

Title: Haemodynamic and renal effects of endothelin receptor antagonism in patients with chronic kidney disease.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101

Title: Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.

Journal: Hypertension (Dallas, Tex. : 1979) 20071101

Title: The effect of doxazosin, finasteride and combination therapy on nocturia in men with benign prostatic hyperplasia.

Journal: The Journal of urology 20071101

Title: Effect of alpha1-adrenoceptor antagonist exposure on prostate cancer incidence: an observational cohort study.

Journal: The Journal of urology 20071101

Title: Effects of alpha1-adrenergic receptor blockade by doxazosin on renin-angiotensin system-regulating aminopeptidase and vasopressin-degrading activities in male and female rat thalamus.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071101

Title: Doxazosin in metabolically complicated hypertension.

Journal: Expert review of cardiovascular therapy 20071101

Title: Posterior reversible encephalopathy syndrome in (low renin) essential hypertension.

Journal: Journal of the Royal Society of Medicine 20071101

Title: New insights into the therapeutic management of morning hypertension with alpha1-adrenergic receptor blockers.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20071101

Title: Add-on effect of bedtime dosing of the alpha(1)-adrenergic receptor antagonist doxazosin on morning hypertension and left ventricular hypertrophy in patients undergoing long-term amlodipine monotherapy.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20071101

Title: Doxazosin blockade of alpha 1-adrenergic receptors increases rat serum progesterone levels: a putative role of ovarian angiotensin III in steroidogenesis.

Journal: Fertility and sterility 20071001

Title: Hemodynamic interaction between a daily dosed phosphodiesterase 5 inhibitor, tadalafil, and the alpha-adrenergic blockers, doxazosin and tamsulosin, in middle-aged healthy male subjects.

Journal: Journal of clinical pharmacology 20071001

Title: Doxazosin relaxes ureteral smooth muscle and inhibits epinephrine-induced ureteral contractility in vitro.

Journal: Urology 20071001

Title: [Case of baroreflex failure after bilateral revascularization of the cervical carotid artery].

Journal: Rinsho shinkeigaku = Clinical neurology 20071001

Title: [Zosteriform cutaneous leiomyoma. Satisfactory treatment with oral doxazosin].

Journal: Actas dermo-sifiliograficas 20070901

Title: Physiologic reactivity to a laboratory stress task among men with benign prostatic hyperplasia.

Journal: Urology 20070901

Title: [Benign prostatic hyperplasia: medical therapy].

Journal: MMW Fortschritte der Medizin 20070816

Title: Editorial comment on: Immunohistochemical distribution of cyclic GMP-dependent protein kinase-1 in human prostate tissue.

Journal: European urology 20070801

Title: Comparative study of modified release alpha-blocker exposure in elderly patients with fractures.

Journal: Pharmacoepidemiology and drug safety 20070801

Title: Unresponsive asystolic cardiac arrest responding to external cardiac pacing in a patient with phaeochromocytoma.

Journal: Anaesthesia 20070801

Title: Pharmacokinetics of doxazosin gastrointestinal therapeutic system after multiple administration in Korean healthy volunteers.

Journal: Drug development and industrial pharmacy 20070801

Title: Management of chronic nonbacterial prostatitis/chronic pelvic pain syndrome.

Journal: Bosnian journal of basic medical sciences 20070801

Title: ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2alpha. Doxazosin inhibits activator protein 2alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade.

Journal: Circulation research 20070720

Title: Old drug, new tricks: the unexpected effect of doxazosin on high-density lipoprotein.

Journal: Circulation research 20070720

Title: [Comparison of different drugs on the treatment of benign prostate hyperplasia].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20070715

Title: [Using of alpha1-adrenoreceptor blockers in urologic practice].

Journal: Voenno-meditsinskii zhurnal 20070701

Title: [Chiral separation of doxazosin and its intermediate by capillary electrophoresis using tetramethylammonium hydroxide to control electroosmotic flow].

Journal: Se pu = Chinese journal of chromatography 20070701

Title: Effects of doxazosin on blood flow and mRNA expression of nitric oxide synthase in the spontaneously hypertensive rat genitourinary tract.

Journal: Life sciences 20070627

Title: Advances in the medical management of benign prostatic hyperplasia.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070619

Title: Incidence of intraoperative floppy iris syndrome in patients on either systemic or topical alpha1-adrenoceptor antagonist.

Journal: American journal of ophthalmology 20070601

Title: Finasteride and doxazosin alone or in combination for the treatment of benign prostatic hyperplasia.

Journal: Expert opinion on pharmacotherapy 20070601

Title: Intraoperative floppy iris syndrome with doxazosin.

Journal: Eye (London, England) 20070501

Title: Alpha antagonists and intraoperative floppy iris syndrome (IFIS) during trabeculectomy.

Journal: Eye (London, England) 20070501

Title: Indirect role of alpha2-adrenoreceptors in anti-ulcer effect mechanism of nimesulide in rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20070501

Title: Doxazosin for the management of distal-ureteral stones.

Journal: Journal of endourology 20070501

Title: Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.

Journal: The pharmacogenomics journal 20070401

Title: Assessment of alpha1-adrenoceptor antagonists in benign prostatic hyperplasia based on the receptor occupancy theory.

Journal: British journal of clinical pharmacology 20070401

Title: A placebo-controlled comparison of the efficiency of triple- and monotherapy in category III B chronic pelvic pain syndrome (CPPS).

Journal: European urology 20070401

Title: Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.

Journal: Nephrology (Carlton, Vic.) 20070401

Title: Intraoperative floppy-iris syndrome with doxazosin.

Journal: Journal of cataract and refractive surgery 20070401

Title: [Perioperative treatment of a patient with ectopic ACTH-producing pheochromocytoma].

Journal: Masui. The Japanese journal of anesthesiology 20070401

Title: Usefulness of the alpha1-blocker doxazosin as a third-line antihypertensive drug.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20070401

Title: Differential effects of urapidil and doxazosin on heart rate.

Journal: European journal of clinical pharmacology 20070301

Title: The effects of systemic alpha-1 adrenergic antagonists on pupil diameter in rats.

Journal: Current eye research 20070301

Title: [Recurrent syncopes secondary to pheochromocytoma].

Journal: Medicina clinica 20070224

Title: LC-MS determination and relative bioavailability of doxazosin mesylate tablets in healthy Chinese male volunteers.

Journal: Journal of pharmaceutical and biomedical analysis 20070219

Title: Doxazosin gastrointestinal therapeutic system versus tamsulosin for the treatment of benign prostatic hyperplasia: a study in Chinese patients.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070201

Title: [Anesthetic management for off-pump coronary artery bypass grafting in a patient with a pheochromocytoma and followed by the resection of the pheochromocytoma].

Journal: Masui. The Japanese journal of anesthesiology 20070201

Title: Separation, characterization, and quantitation of process-related substances of the anti-hypertensive drug doxazosin mesylate by reversed-phase LC with PDA and ESI-MS as detectors.

Journal: Journal of chromatographic science 20070201

Title: [Effects of doxazosin enantiomers on alpha-adrenoceptors of isolated rabbit blood vessels].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070201

Title: Contractile responses of rabbit bladder neck to adrenaline, acetylcholine and papaverine after doxazosin treatment.

Journal: International urology and nephrology 20070101

Title: The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Heart Failure Validation Study: diagnosis and prognosis.

Journal: American heart journal 20070101

Title: Effects of doxazosin and amlodipine on mean platelet volume and serum serotonin level in patients with metabolic syndrome: a randomised, controlled study.

Journal: Clinical drug investigation 20070101

Title: Doxazosin-induced clusterin expression and apoptosis in prostate cancer cells.

Journal: Urologic oncology 20070101

Title: Targeting pituitary tumors.

Journal: Hormone research 20070101

Title: Assessment of cognitive function in patients with essential hypertension treated with lercanidipine.

Journal: Vascular health and risk management 20061201

Title: Doxazosin in the treatment of benign prostatic hypertrophy: an update.

Journal: Clinical interventions in aging 20061201

Title: High-performance liquid chromatographic determination of doxazosin in human plasma for bioequivalence study of controlled release doxazosin tablets.

Journal: Biomedical chromatography : BMC 20061101

Title: Chiral selective effects of doxazosin enantiomers on blood pressure and urinary bladder pressure in anesthetized rats.

Journal: Acta pharmacologica Sinica 20061101

Title: Efficacy and safety of tamsulosin hydrochloride compared to doxazosin in the treatment of Indonesian patients with lower urinary tract symptoms due to benign prostatic hyperplasia.

Journal: International journal of urology : official journal of the Japanese Urological Association 20061101

Title: Adrenergic stimulation and blocking of hormonal secretion activity of cultured cow granulosa cells.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061101

Title: The influence of alpha-adrenergic receptors stimulator and blockers and beta-blocker on the ovary and endocrinological activity in heifers during superovulation.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061101

Title: Evaluation of short term clinical effects and presumptive mechanism of botulinum toxin type A as a treatment modality of benign prostatic hyperplasia.

Journal: Yonsei medical journal 20061031

Title: On-line simultaneous removal of human serum albumin and enrichment of doxazosin using a weak cation-exchange monolithic column.

Journal: Journal of chromatography. A 20061006

Title: A randomised, double-blind study comparing the efficacy and tolerability of controlled-release doxazosin and tamsulosin in the treatment of benign prostatic hyperplasia in Brazil.

Journal: International journal of clinical practice 20061001

Title: Myostatin expression in ventricular myocardium in a rat model of volume-overload heart failure.

Journal: European journal of clinical investigation 20061001

Title: Intraoperative floppy iris syndrome.

Journal: Ophthalmology 20061001

Title: [A novel microemulsion electrokinetic chromatography for measuring lipid-water partition coefficients of pharmaceuticals].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20061001

Title: The role of the alpha-1 adrenoceptor in modulating human mesangial cell matrix production.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060901

Title: Incidence and predictors of angioedema in elderly hypertensive patients at high risk for cardiovascular disease: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060901

Title: Validation and pharmacokinetic application of a method for determination of doxazosin in human plasma by high-performance liquid chromatography.

Journal: Biomedical chromatography : BMC 20060801

Title: alpha-blocker treatment of urolithiasis.

Journal: European urology 20060801

Title: UPLC-MS/MS determination of doxazosine in human plasma.

Journal: Analytical and bioanalytical chemistry 20060801

Title: Benign prostatic hyperplasia (BPH).

Journal: Harvard men's health watch 20060801

Title: Doxazosin induces activation of GADD153 and cleavage of focal adhesion kinase in cardiomyocytes en route to apoptosis.

Journal: Cardiovascular research 20060701

Title: Survival benefits of different antiadrenergic interventions in pressure overload left ventricular hypertrophy/failure.

Journal: Hypertension (Dallas, Tex. : 1979) 20060701

Title: Enantiomeric resolution of doxazosin mesylate and its process-related substances on polysaccharide chiral stationary phases.

Journal: Journal of pharmaceutical and biomedical analysis 20060607

Title: Effect of doxazosin with and without rho-kinase inhibitor on human corpus cavernosum smooth muscle in the presence of bladder outlet obstruction.

Journal: The Journal of urology 20060601

Title: Anxiety-induced plasma norepinephrine augmentation increases reactive oxygen species formation by monocytes in essential hypertension.

Journal: American journal of hypertension 20060601

Title: Role of diuretics in the prevention of heart failure: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial.

Journal: Circulation 20060509

Title: Preventing vascular events due to elevated blood pressure.

Journal: Circulation 20060509

Title: The role of noradrenaline in the generation of the preovulatory LH surge in the ewe.

Journal: Domestic animal endocrinology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The effect of carvedilol on metabolic parameters in patients with metabolic syndrome.

Journal: International heart journal 20060501

Title: [One-year controlled therapy with doxazosin in patients with pulmonary hypertension due to chronic obstructive pulmonary disease].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060501

Title: Baseline factors as predictors of clinical progression of benign prostatic hyperplasia in men treated with placebo.

Journal: The Journal of urology 20060401

Title: Treatment and pharmacologic management of BPH in the context of common comorbidities.

Journal: The American journal of managed care 20060401

Title: Effect of doxazosin on C-reactive protein plasma levels and on nitric oxide in patients with hypertension.

Journal: Journal of cardiovascular pharmacology 20060401

Title: Association of IFIS and vasodepressor medication.

Journal: Journal of cataract and refractive surgery 20060401

Title: Are all alpha-blockers created the same?

Journal: European urology 20060301

Title: Beneficial effects of extended-release doxazosin and doxazosin standard on sexual health.

Journal: BJU international 20060301

Title: Clinical efficacy and tolerability of alpha-blocker doxazosin as add-on therapy in patients with hypertension and impaired glucose metabolism.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20060301

Title: Controlled-release doxazosin as combination therapy in hypertension: the GATES study.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060301

Title: Doxazosin gastrointestinal therapeutic system: a clinical perspective.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060301

Title: Comparison of doxazosin GITS and standard doxazosin in the treatment of high blood pressure.

Journal: International journal of clinical pharmacology and therapeutics 20060301

Title: [The objective of medical treatment: relieve the symptoms or stop the course?].

Journal: Annales d'urologie 20060301

Title: The Japan Morning Surge-1 (JMS-1) study: protocol description.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20060301

Title: Should patients with benign prostatic hypertrophy stop taking doxazosin in the light of the ALLHAT study?

Journal: International journal of cardiology 20060215

Title: Comparison of the protein profile of established and regressed hypertension-induced left ventricular hypertrophy.

Journal: Journal of proteome research 20060201

Title: In vivo studies on the effects of alpha1-adrenoceptor antagonists on pupil diameter and urethral tone in rabbits.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060201

Title: Effect of doxazosin gastrointestinal therapeutic system on patients with uncontrolled hypertension: the ASOCIA Study.

Journal: Journal of cardiovascular pharmacology 20060201

Title: Effect of doxazosin on oxidative stress related proteins in essential hypertensive patients.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20060201

Title: Antinociceptive and behavioral effects of ribavirin in mice.

Journal: Pharmacology, biochemistry, and behavior 20060201

Title: Effect of doxazosin gastrointestinal therapeutic system on platelet degranulation and platelet-leukocyte microaggregate formation induced by physiologic shear stress in hypertension.

Journal: Thrombosis research 20060101

Title: Long-term follow-up study to evaluate the efficacy and safety of the doxazosin gastrointestinal therapeutic system in patients with benign prostatic hyperplasia with or without concomitant hypertension.

Journal: BJU international 20060101

Title: Doxazosin induces apoptosis of benign and malignant prostate cells via a death receptor-mediated pathway.

Journal: Cancer research 20060101

Title: Effect of doxazosin on oxidative stress-related proteins in benign prostatic hyperplasia.

Journal: Urologia internationalis 20060101

Title: Combination therapy with doxazosin and finasteride for benign prostatic hyperplasia in patients with lower urinary tract symptoms and a baseline total prostate volume of 25 ml or greater.

Journal: The Journal of urology 20060101

Title: Combination regimen in the treatment of chronic prostatitis.

Journal: Archives of andrology 20060101

Title: Cytoplasmic free calcium mobilization in platelets, expression of P-selectin, phosphatidylserine, and microparticle formation, measured by whole blood flow cytometry, in hypertensive patients. Effect of doxazosin GITS.

Journal: Thrombosis research 20060101

Title: Effects of alpha(1)-adrenoceptor antagonists on male sexual function.

Journal: Drugs 20060101

Title: Doxazosin and serotonin (5-HT) receptor (1A, 2A, and 4) antagonists inhibit 5-HT-mediated human cavernosal contraction.

Journal: Journal of andrology 20060101

Title: Pharmacologic expulsive treatment of ureteral calculi.

Journal: The Annals of pharmacotherapy 20060101

Title: [The comparative study on selective alpha1-blocker and behavioural therapy in the treatment of discoordinated voiding in children].

Journal: Przeglad lekarski 20060101

Title: [The system of management nocturnal enuresis based on functional classification].

Journal: Przeglad lekarski 20060101

Title: Potentially inappropriate medication prescribing for elderly outpatients in Emilia Romagna, Italy: a population-based cohort study.

Journal: Drugs & aging 20060101

Title: Treatment of detrusor sphincter dyssynergia with baclofen and doxazosin.

Journal: International urology and nephrology 20060101

Title: Long-term organ protection by doxazosin and/or quinapril as antihypertensive therapy.

Journal: Journal of nephrology 20060101

Title: Linguistic adaptation and validation of the Spanish version of the Benign Prostatic Hyperplasia-Patient Impact Measure (BPH-PIM).

Journal: Clinical drug investigation 20060101

Title: Synergistic effect of doxazosin and acarbose in improving metabolic control in patients with impaired glucose tolerance.

Journal: Clinical drug investigation 20060101

Title: [Using doxasosine and finasteride combination in the treatment of prostate adenoma].

Journal: Urologiia (Moscow, Russia : 1999) 20060101

Title: Multiple cutaneous and uterine leiomyomatosis (Reed's syndrome).

Journal: Dermatology online journal 20051230

Title: Alpha1-adrenergic receptor antagonists: novel therapy for pituitary adenomas.

Journal: Molecular endocrinology (Baltimore, Md.) 20051201

Title: Doxazosin induces apoptosis in LNCaP prostate cancer cell line through DNA binding and DNA-dependent protein kinase down-regulation.

Journal: International journal of oncology 20051201

Title: Bioequivalence evaluation of two formulations of doxazosin tablet in healthy thai male volunteers.

Journal: Drug development and industrial pharmacy 20051201

Title: Alpha1-adrenergic antagonists and floppy iris syndrome: tip of the iceberg?

Journal: Ophthalmology 20051201

Title: Sympathectomy or doxazosin, but not propranolol, blunt myocardial interstitial fibrosis in pressure-overload hypertrophy.

Journal: Hypertension (Dallas, Tex. : 1979) 20051101

Title: The effects of alpha-adrenoceptor antagonists on the urethral perfusion pressure of the female rat.

Journal: BJU international 20051101

Title: Efficacy of the combination of an alpha1-blocker with an anticholinergic agent in the treatment of lower urinary tract symptoms associated with bladder outlet obstruction.

Journal: Expert opinion on pharmacotherapy 20051101

Title: Combination treatment with propiverine hydrochloride plus doxazosin controlled release gastrointestinal therapeutic system formulation for overactive bladder and coexisting benign prostatic obstruction: a prospective, randomized, controlled multicenter study.

Journal: The Journal of urology 20051001

Title: Can alpha-blocker therapy be an alternative to biofeedback for dysfunctional voiding and urinary retention? A prospective study.

Journal: The Journal of urology 20051001

Title: Hemodynamic effects of alpha1-adrenoceptor antagonist, doxazosin, in patients with chronic congestive heart failure.

Journal: Journal of cardiovascular pharmacology 20051001

Title: Effects of doxazosin on ambulatory blood pressure and sympathetic nervous activity in hypertensive Type 2 diabetic patients with overt nephropathy.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20051001

Title: [ASCOT-BPLA Study raises new questions regarding: which is the best initial antihypertensive drug?].

Journal: MMW Fortschritte der Medizin 20050929

Title: Oral treatment of the TRAMP mice with doxazosin suppresses prostate tumor growth and metastasis.

Journal: The Prostate 20050901

Title: A double-blind placebo-controlled study evaluating the onset of action of doxazosin gastrointestinal therapeutic system in the treatment of benign prostatic hyperplasia.

Journal: European urology 20050901

Title: One drug fits all.

Journal: BJU international 20050901

Title: Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis.

Journal: Oncogene 20050811

Title: Benign prostatic hyperplasia cell line viability and modulation of jm-27 by doxazosin and Ibuprofen.

Journal: The Journal of urology 20050701

Title: Pharmacogenetic association of the angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure and cardiovascular risk in relation to antihypertensive treatment: the Genetics of Hypertension-Associated Treatment (GenHAT) study.

Journal: Circulation 20050628

Title: [Inhibitory effect of doxazosin on the growth of transplanted tumor of prostate cancer cell PC-3 in nude mice].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20050618

Title: Molecular classification of doxazosin-induced alterations in the rat prostate using gene expression profiling.

Journal: Life sciences 20050610

Title: The comparison and efficacy of 3 different alpha1-adrenergic blockers for distal ureteral stones.

Journal: The Journal of urology 20050601

Title: Double-blind placebo controlled study of alpha-adrenergic receptor antagonists (doxazosin) for treatment of voiding dysfunction in the pediatric population.

Journal: The Journal of urology 20050601

Title: Effects of doxazosin and irbesartan on blood pressure and metabolic control in patients with type 2 diabetes and hypertension.

Journal: Journal of cardiovascular pharmacology 20050601

Title: [Therapeutic strategy for morning blood pressure elevation in elderly hypertensives].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050601

Title: Doxazosin versus bendrofluazide: a comparison of the metabolic effects in British South Asians with hypertension.

Journal: The British journal of general practice : the journal of the Royal College of General Practitioners 20050601

Title: Acute intoxication with doxazosin.

Journal: Human & experimental toxicology 20050601

Title: [Effects of doxazosin mosylate and phenoxybenzamine in preoperative volume expansion of pheochromocytoma: a comparative study in 38 cases].

Journal: Zhonghua yi xue za zhi 20050601

Title: Polymorphism of doxazosin mesylate.

Journal: Archives of pharmacal research 20050601

Title: Doxazosin GITS versus standard doxazosin in mild to moderate hypertension.

Journal: International journal of cardiology 20050511

Title: Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder.

Journal: BJU international 20050501

Title: The bedtime administration of doxazosin controls morning hypertension and albuminuria in patients with type-2 diabetes: evaluation using home-based blood pressure measurements.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20050501

Title: [Antihypertensive therapy and congestive heart failure].

Journal: Medicina clinica 20050409

Title: The perioperative management of a patient with complex single ventricle physiology and pheochromocytoma.

Journal: Anesthesia and analgesia 20050401

Title: Molecular targets of doxazosin in human prostatic stromal cells.

Journal: The Prostate 20050301

Title: The clinical efficacy and tolerability of doxazosin standard and gastrointestinal therapeutic system for benign prostatic hyperplasia.

Journal: BJU international 20050301

Title: Finasteride with doxazosin to reduce BPH progression.

Journal: The Nurse practitioner 20050301

Title: [Alfa-blockade with doxazosin vs tamsulozin in combination of intermittent androgen blockade in patients with prostate cancer].

Journal: Georgian medical news 20050301

Title: [Impact of 30 day therapy with doxazosin--alpha1 adrenergic blocker on pulmonary hemodynamics in patients with secondary pulmonary hypertension due to chronic obstructive pulmonary disease].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050301

Title: Doxazosin inhibits human vascular endothelial cell adhesion, migration, and invasion.

Journal: Journal of cellular biochemistry 20050201

Title: The vascular effects of doxazosin in hypertension complicated by metabolic syndrome.

Journal: Coronary artery disease 20050201

Title: pH-mediated acid stacking with reverse pressure for the analysis of cationic pharmaceuticals in capillary electrophoresis.

Journal: Electrophoresis 20050201

Title: Doxazosin for benign prostatic hyperplasia: an open-label, baseline-controlled study in Korean general practice.

Journal: International journal of urology : official journal of the Japanese Urological Association 20050201

Title: Re: an economic evaluation of doxazosin, finasteride and combination therapy in the treatment of benign prostatic hyperplasia.

Journal: The Canadian journal of urology 20050201

Title: Improvement of doxazosin determination in human plasma using high-performance liquid chromatography with fluorescence detection.

Journal: Journal of chromatographic science 20050201

Title: Primary bladder neck dysfunction in children and adolescents II: results of treatment with alpha-adrenergic antagonists.

Journal: The Journal of urology 20050101

Title: alpha1-Adrenergic receptor antagonists induce production of IL-18 and expression of ICAM-1 and CD40 in human monocytes.

Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20050101

Title: Efficacy of extended-release doxazosin and doxazosin standard in patients with concomitant benign prostatic hyperplasia and sexual dysfunction.

Journal: BJU international 20050101

Title: Clinical ease of using doxazosin in BPH patients with and without hypertension.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Carvedilol prevents cardiac hypertrophy and overexpression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in pressure-overloaded rat heart.

Journal: Journal of biomedical science 20050101

Title: Different effects on inhibition of cardiac hypertrophy in spontaneously hypertensive rats by monotherapy and combination therapy of adrenergic receptor antagonists and/or the angiotensin II type 1 receptor blocker under comparable blood pressure reduction.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20050101

Title: Doxazosin gastrointestinal therapeutic system: a review of its use in benign prostatic hyperplasia.

Journal: Drugs 20050101

Title: Controlled-release doxazosin in the treatment of benign prostatic hyperplasia.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Growth inhibitory effect of doxazosin on prostate and bladder cancer cells. Is the serotonin receptor pathway involved?

Journal: Anticancer research 20050101

Title: [Doxazosine associated to renin-angiotensin blockers and calcioantagonists in chronic renal failure patients].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101

Title: Successful alpha-1 receptor blockade therapy in a toddler with infrequent and difficult voiding.

Journal: Advances in therapy 20050101

Title: Eliciting preferences for drug treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia.

Journal: The Journal of urology 20041201

Title: Effects of chronic administration of doxazosin on alpha1-adrenoceptors in the rat prostate.

Journal: The Journal of urology 20041201

Title: Doxazosin for treating lower urinary tract symptoms compatible with benign prostatic obstruction: a systematic review of efficacy and adverse effects.

Journal: BJU international 20041201

Title: Blood pressure and urologists: like oil and water?

Journal: BJU international 20041201

Title: Interaction between the phosphodiesterase 5 inhibitor, tadalafil and 2 alpha-blockers, doxazosin and tamsulosin in healthy normotensive men.

Journal: The Journal of urology 20041101

Title: MTOPS: conclusions about invasive therapy for BPH should be interpreted with caution.

Journal: BJU international 20041101

Title: Parameters of cell energy metabolism during stress in laboratory animals and energotropic effect of alpha1-adrenoblocker doxazosin.

Journal: Bulletin of experimental biology and medicine 20041101

Title: Doxazosin treatment causes differential alterations of alpha 1-adrenoceptor subtypes in the rat kidney, heart and aorta.

Journal: Life sciences 20041008

Title: Inhibition of mitogenic signaling and induction of apoptosis in human bladder smooth muscle cells treated with doxazosin.

Journal: The Journal of urology 20041001

Title: Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder.

Journal: BJU international 20041001

Title: Doxazosin-induced up-regulation of alpha 1A-adrenoceptor mRNA in the rat lower urinary tract.

Journal: Canadian journal of physiology and pharmacology 20041001

Title: [Effect of modified liberation doxazosin on blood pressure, insulin resistance, and catecholamine secretion in patients with true resistant hypertension].

Journal: Medicina clinica 20040911

Title: Importance of antioxidant and antiapoptotic effects of beta-receptor blockers in heart failure therapy.

Journal: American journal of physiology. Heart and circulatory physiology 20040901

Title: After ALLHAT: doxazosin for the treatment of benign prostatic hyperplasia.

Journal: Expert opinion on pharmacotherapy 20040901

Title: [Therapy of benign prostatic hyperplasia with finasteride and doxazosin -- long-term studies support the combination].

Journal: Aktuelle Urologie 20040901

Title: Doxazosin in the sigmoid.

Journal: Lancet (London, England) 20040901

Title: Long-term efficacy of doxazosin plus atenolol in the management of severe and sustained arterial hypertension and reversibility of the cardiac damage induced by chronic cathecolamine excess. A case report in a young girl with recurrent, functioning paraganglioma.

Journal: Journal of endocrinological investigation 20040901

Title: Pharmacological exploitation of the alpha1-adrenoreceptor antagonist doxazosin to develop a novel class of antitumor agents that block intracellular protein kinase B/Akt activation.

Journal: Journal of medicinal chemistry 20040826

Title: Induction of anoikis by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase.

Journal: Urological research 20040801

Title: Morning blood pressure surge and hypertensive cerebrovascular disease: role of the alpha adrenergic sympathetic nervous system.

Journal: American journal of hypertension 20040801

Title: An economic evaluation of doxazosin, finasteride and combination therapy in the treatment of benign prostatic hyperplasia.

Journal: The Canadian journal of urology 20040801

Title: Doxazosin effects on cholinergic and adrenergic responses in rat isolated detrusor smooth muscle preparations from obstructed bladder.

Journal: Journal of pharmacological sciences 20040701

Title: Renoprotective effect of angiotensin-converting enzyme inhibitor combined with alpha1-adrenergic antagonist in spontaneously hypertensive rats with renal ablation.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040701

Title: The role of alpha-blockers in the management of prostate cancer.

Journal: Expert opinion on pharmacotherapy 20040601

Title: Inhibition of human ether-a-go-go-related gene potassium channels by alpha 1-adrenoceptor antagonists prazosin, doxazosin, and terazosin.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040501

Title: Two-drug therapy is best for symptomatic prostate enlargement: could a combination of doxazosin and finasteride change clinical practice?

Journal: BJU international 20040501

Title: Combination of finasteride and doxazosin for the treatment of benign prostatic hyperplasia.

Journal: Expert opinion on pharmacotherapy 20040501

Title: Apoptotic impact of alpha1-blockers on prostate cancer growth: a myth or an inviting reality?

Journal: The Prostate 20040401

Title: Comparative efficacy of two alpha-adrenoreceptor antagonists, doxazosin and alfuzosin, in patients with lower urinary tract symptoms from benign prostatic enlargement.

Journal: BJU international 20040401

Title: Successful treatment of pain in two patients with cutaneous leiomyomata with the oral alpha-1 adrenoceptor antagonist, doxazosin.

Journal: The British journal of dermatology 20040401

Title: [Treatment with Doxazosin in 3347 patients with lower urinary tract symptoms. Impact on sexual function. The impros study].

Journal: Actas urologicas espanolas 20040401

Title: Finasteride in benign prostatic hyperplasia.

Journal: The New England journal of medicine 20040325

Title: Cardiovascular outcomes using doxazosin vs. chlorthalidone for the treatment of hypertension in older adults with and without glucose disorders: a report from the ALLHAT study.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20040301

Title: [Alpha blocker for protection against hypertensive target-organ damage].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040301

Title: [ALLHAT trial--antithesis to the overuse of vasodilating antihypertensive drugs].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040301

Title: Administration-time-dependent effects of doxazosin GITS on ambulatory blood pressure of hypertensive subjects.

Journal: Chronobiology international 20040301

Title: Male breast cancer during finasteride therapy.

Journal: Journal of the National Cancer Institute 20040218

Title: Prostate apoptosis after doxazosin treatment in the spontaneous hypertensive rat model.

Journal: BJU international 20040201

Title: Herbal and vitamin supplement use in a prostate cancer screening population.

Journal: Urology 20040201

Title: Patients with uncontrolled hypertension or concomitant hypertension and benign prostatic hyperplasia.

Journal: Clinical cardiology 20040201

Title: Drug combo stalls BPH progression.

Journal: Health news (Waltham, Mass.) 20040201

Title: A current review of medical therapy for benign prostatic hyperplasia.

Journal: The Journal of the American Osteopathic Association 20040201

Title: Validated specific HPLC methods for determination of prazosin, terazosin and doxazosin in the presence of degradation products formed under ICH-recommended stress conditions.

Journal: Journal of pharmaceutical and biomedical analysis 20040127

Title: [ALLHAT--remaining questions await answers].

Journal: Lakartidningen 20040115

Title: [Choice of antihypertensive agent--insignificant role of doxazosin (Alfadil). How are evidence-based recommendations implemented?].

Journal: Lakartidningen 20040115

Title: Impact of clinical trial results on national trends in alpha-blocker prescribing, 1996-2002.

Journal: JAMA 20040107

Title: Clinical application of wave intensity for the treatment of essential hypertension.

Journal: Heart and vessels 20040101

Title: Doxazosin controlled release vs tamsulosin in the management of benign prostatic hyperplasia: an efficacy analysis.

Journal: International journal of clinical practice 20040101

Title: [Doxazosin in the gastrointestinal therapeutic system (GITS) formulation and trial without catheter after acute urinary retention due to BPH. Dose increase action on recovery effect].

Journal: Actas urologicas espanolas 20040101

Title: Relationship between body mass index and anti-hypertensive efficacy of doxazosin according to a survey of Japanese patients.

Journal: The Journal of international medical research 20040101

Title: Clinical usefulness of doxazosin in patients with type 2 diabetes complicated by hypertension: effects on glucose and lipid metabolism.

Journal: The Journal of international medical research 20040101

Title: [Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101

Title: [Epidemiology of lower urinary tract symptoms and use of doxazosin in the treatment of early stages of benign prostate hyperplasia].

Journal: Likars'ka sprava 20040101

Title: Terazosin and doxazosin in the treatment of BPH: results of a randomized study with crossover in non-responders.

Journal: Urologia internationalis 20040101

Title: Long-term treatment with doxazosin in men with benign prostatic hyperplasia: 10-year follow-up.

Journal: International urology and nephrology 20040101

Title: Cost-effectiveness of tamsulosin, doxazosin, and terazosin in the treatment of benign prostatic hyperplasia.

Journal: Journal of managed care pharmacy : JMCP 20040101

Title: [Viagra effects on polysystemic energy metabolism in stress (an experimental study)].

Journal: Urologiia (Moscow, Russia : 1999) 20040101

Title: [Analysis of doxazosin efficacy in the treatment of the benign prostatic enlargement].

Journal: Medicinski arhiv 20040101

Title: [Use of alpha-adrenoblockers in therapy of benign prostatic hyperplasia in patients with arterial hypertension].

Journal: Terapevticheskii arkhiv 20040101

Title: Pheochromocytoma.

Journal: Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society 20040101

Title: A comparison of four different alpha1-blockers in benign prostatic hyperplasia patients with and without diabetes.

Journal: Scandinavian journal of urology and nephrology 20040101

Title: [LUTS in women and possible therapeutic effects of alfa1-adrenoblockers].

Journal: Khirurgiia 20040101

Title: The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia.

Journal: The New England journal of medicine 20031218

Title: [Doxazosin and heart failure: a clinical conclusion is wanted].

Journal: Lakartidningen 20031218

Title: [Alfadil--positive documentation when it comes to safety is missing].

Journal: Lakartidningen 20031218

Title: [Alfadil and heart failure--clinical conclusions do exist!].

Journal: Lakartidningen 20031204

Title: Protonation site and hydrogen bonding in anhydrous and hydrated crystalline forms of doxazosin mesylate from powder data.

Journal: Acta crystallographica. Section B, Structural science 20031201

Title: Relapse of Graves' disease in a patient with pheochromocytoma.

Journal: Endocrine journal 20031201

Title: Doxazosin GITS versus hydrochlorothiazide as add-on therapy in patients with uncontrolled hypertension.

Journal: Blood pressure. Supplement 20031201

Title: [Doxazosin and heart failure: truthful information--for the sake of patients].

Journal: Lakartidningen 20031127

Title: [Treatment of hypertension in a clinical trial. Depot alpha 1 blocker simplifies dosing].

Journal: MMW Fortschritte der Medizin 20031120

Title: [Two drugs have a better outcome. Finasteride plus alpha blocker improves urine flow].

Journal: MMW Fortschritte der Medizin 20031120

Title: Short-term subjective efficacy of doxazosin in predicting probability of prostatectomy in the management of benign prostatic hyperplasia in patients with severe symptoms.

Journal: International journal of urology : official journal of the Japanese Urological Association 20031101

Title: The effects of alpha and beta blockade on ventilatory responses to exercise in chronic heart failure.

Journal: Heart (British Cardiac Society) 20031001

Title: Alpha blocker therapy for children with dysfunctional voiding and urinary retention.

Journal: The Journal of urology 20031001

Title: Doxazosin, an alpha-1 antagonist, prevents further progression of the advanced atherosclerotic lesion in hypercholesterolemic hamsters.

Journal: Metabolism: clinical and experimental 20031001

Title: [Benign prostatic syndrome. 3-step plan for the treatment].

Journal: MMW Fortschritte der Medizin 20030925

Title: [Pharmacologic treatment of benign prostatic hyperplasia].

Journal: Orvosi hetilap 20030914

Title: Diuretic versus alpha-blocker as first-step antihypertensive therapy: final results from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Hypertension (Dallas, Tex. : 1979) 20030901

Title: Effect of the alpha-adrenergic blocker, doxazosin, on endothelial function and insulin action.

Journal: Metabolism: clinical and experimental 20030901

Title: Effect of doxazosin on insulin resistance in hypertensive patients with obesity.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030901

Title: Chronic ischemia increases prostatic smooth muscle contraction in the rabbit.

Journal: The Journal of urology 20030801

Title: The role of combination therapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia.

Journal: Current urology reports 20030801

Title: Pharmaceutical review.

Journal: BJU international 20030801

Title: Effects of preweaning doxazosin treatment on adult pressure in the spontaneously hypertensive rat.

Journal: Clinical and experimental pharmacology & physiology 20030801

Title: Efficacy and safety of doxazosin GITS in hypertensive renal transplant patients: comparison of 8 and 4 mg.

Journal: Transplantation proceedings 20030801

Title: Doxazosin GITS trough to peak ratio and 24-hour blood pressure monitoring in the management of hypertension in renal transplant patients.

Journal: Transplantation proceedings 20030801

Title: Effectiveness of alpha1-adrenergic blockers in boys with low urinary flow rate and urinary incontinence.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20030801

Title: [5-alpha reductase inhibitors plus alpha blockers. A combination therapy keeps a common disease checked].

Journal: MMW Fortschritte der Medizin 20030710

Title: Doxazosin as combination therapy for patients with stage 1 and stage 2 hypertension.

Journal: Journal of cardiovascular pharmacology 20030601

Title: Effect of doxazosin GITS on 24-hour blood pressure profile in patients with stage 1 to stage 2 primary hypertension.

Journal: Blood pressure monitoring 20030601

Title: Flow cytometric analysis of platelet activation in hypertensive patients. Effect of doxazosin.

Journal: Thrombosis research 20030601

Title: Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction.

Journal: British journal of cancer 20030519

Title: Safety and effectiveness of replacing standard doxazosin with doxazosin in the gastrointestinal therapeutic system (GITS) formulation in elderly hypertensive patients.

Journal: International journal of clinical practice 20030501

Title: Effect of doxazosin GITS on blood pressure in hypertensive and normotensive patients: a review of hypertension and BPH studies.

Journal: Blood pressure. Supplement 20030501

Title: Doxazosin and terazosin suppress prostate growth by inducing apoptosis: clinical significance.

Journal: The Journal of urology 20030401

Title: Diuretics: older, cheaper, better.

Journal: The Johns Hopkins medical letter health after 50 20030401

Title: By the way, doctor. I'm 77 and have an enlarged prostate. I take Proscar once a day and saw palmetto three times a day. Yet I still have to get up two to seven times a night to urinate. What can I do to reduce the frequency of urination?

Journal: Harvard health letter 20030401

Title: [ALLHAT: Old Hat Hits All? On selection of the optimal antihypertensive drug].

Journal: Wiener klinische Wochenschrift 20030331

Title: Anoikis induction by quinazoline based alpha 1-adrenoceptor antagonists in prostate cancer cells: antagonistic effect of bcl-2.

Journal: The Journal of urology 20030301

Title: The ALLHAT Trial. Diuretics are still the preferred initial drugs for high blood pressure.

Journal: Cleveland Clinic journal of medicine 20030301

Title: Benign prostatic hyperplasia.

Journal: Hospital medicine (London, England : 1998) 20030201

Title: Medical treatment for urinary retention in rehabilitating elderly women: is it necessary?

Journal: Aging clinical and experimental research 20030201

Title: [Old or new antihypertensive drugs? Consequences from ALLHAT. Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial].

Journal: Deutsche medizinische Wochenschrift (1946) 20030131

Title: [Misleading advertising claims about the indication of doxazosin (Cardura) for type 2 diabetes mellitus and hypertension].

Journal: Nederlands tijdschrift voor geneeskunde 20030118

Title: [Established blood pressure drug wins out in a comparative study. In hypertension, a diuretic first!].

Journal: MMW Fortschritte der Medizin 20030116

Title: Doxazosin induces apoptosis in cardiomyocytes cultured in vitro by a mechanism that is independent of alpha1-adrenergic blockade.

Journal: Circulation 20030107

Title: Stromal/epithelial interactions of murine prostatic cell lines in vivo: a model for benign prostatic hyperplasia and the effect of doxazosin on tissue size.

Journal: The Prostate 20030101

Title: Efficacy and tolerability of doxazosin and finasteride, alone or in combination, in treatment of symptomatic benign prostatic hyperplasia: the Prospective European Doxazosin and Combination Therapy (PREDICT) trial.

Journal: Urology 20030101

Title: A randomized, double-blind crossover study of tamsulosin and controlled-release doxazosin in patients with benign prostatic hyperplasia.

Journal: BJU international 20030101

Title: [The incidence, features of the course, and treatment of arterial hypertension in patients with prostate hyperplasia].

Journal: Likars'ka sprava 20030101

Title: ALLHAT. Is it all hat?

Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20030101

Title: [Tonocardin (doxazosin) in treating lower urinary tract symptoms].

Journal: Urologiia (Moscow, Russia : 1999) 20030101

Title: [The new (old) knowledge in primary prevention of stroke. It depends on lowering of blood pressure].

Journal: MMW Fortschritte der Medizin 20030101

Title: [Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].

Journal: MMW Fortschritte der Medizin 20030101

Title: [Dynamics of immunologic indices in patients with ischemic heart disease on a course of doxazosin therapy].

Journal: Likars'ka sprava 20030101

Title: [Efficacy and safety in the use of doxazosin (cardura) in the treatment of patients with benign prostatic hypertrophy (bph)].

Journal: Urologiia (Moscow, Russia : 1999) 20030101

Title: [Possibility of predicting the use of doxazosin in the treatment of arterial hypertension].

Journal: Klinicheskaia meditsina 20030101

Title: Characteristics and lipid distribution of a large, high-risk, hypertensive population: the lipid-lowering component of the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20030101

Title: [Effects of monotherapy with an alpha1-adrenoblocker doxazosin and its combination with beta1-adrenoblocker atenolol on hemodynamics, reversible myocardial ischemia in postmyocardial infarction patients with arterial hypertension].

Journal: Klinicheskaia meditsina 20030101

Title: Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.

Journal: Hypertension (Dallas, Tex. : 1979) 20021201

Title: Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20021201

Title: Doxazosin, but not amlodipine decreases insulin resistance in patients with chronic renal failure: a prospective, randomized-controlled study.

Journal: Clinical nephrology 20021201

Title: Second opinion. I have benign prostatic hyperplasia. The drug my doctor prescribed has helped somewhat, but I'm still making a lot of trips to the bathroom at night. Short of surgery, are there any new approaches to managing this condition that might be more helpful?

Journal: Mayo Clinic health letter (English ed.) 20021201

Title: [Misleading advertising claims about the indication of doxazosin (Cardura) for type 2 diabetes mellitus and hypertension].

Journal: Nederlands tijdschrift voor geneeskunde 20021102

Title: [5-alpha reductase inhibitors or alpha blockers? The combination brakes best prostatic hyperplasia].

Journal: MMW Fortschritte der Medizin 20021031

Title: [Management of hypertensive patients with left ventricular hypertrophy].

Journal: Presse medicale (Paris, France : 1983) 20021001

Title: Effect of doxazosin on arterial elasticity: functional versus structural changes.

Journal: Journal of clinical pharmacology 20021001

Title: Prophylactic versus therapeutic alpha-blockers after permanent prostate brachytherapy.

Journal: Urology 20021001

Title: [Doxazosin and urinary incontinence].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20021001

Title: Doxazosin and hydrochlorothiazide equally affect arterial wall thickness in hypertensive males with hypercholesterolaemia (the DAPHNE study). Doxazosin Atherosclerosis Progression Study in Hypertensives in the Netherlands.

Journal: The Netherlands journal of medicine 20021001

Title: Relationship of antihypertensive treatment regimens and change in blood pressure to risk for heart failure in hypertensive patients randomly assigned to doxazosin or chlorthalidone: further analyses from the Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial.

Journal: Annals of internal medicine 20020903

Title: Summaries for patients. Blood pressure drugs and heart failure.

Journal: Annals of internal medicine 20020903

Title: Doxazosin and ALLHAT trial: a response.

Journal: American journal of hypertension 20020901

Title: The effect of doxazosin on sexual function in patients with benign prostatic hyperplasia, hypertension, or both.

Journal: International journal of clinical practice 20020901

Title: Effects of acute administration of doxazosin on fasting and postprandial haemodynamics and lipid metabolism in healthy subjects.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020901

Title: alpha1-Adrenergic blockers in young men with primary bladder neck obstruction.

Journal: The Journal of urology 20020801

Title: Effect of doxazosin on stretch-activated adenosine triphosphate release in bladder urothelial cells from patients with benign prostatic hyperplasia.

Journal: Urology 20020801

Title: Two-drug therapy is best for symptomatic prostate enlargement: combination should change clinical practice.

Journal: Journal of the American College of Surgeons 20020801

Title: Efficacy and safety of doxazosin for perioperative management of patients with pheochromocytoma.

Journal: World journal of surgery 20020801

Title: Managing benign prostatic hyperplasia.

Journal: American family physician 20020701

Title: [Hypertension and metabolic syndrome in population of one company. Monotherapy with amlodipine and doxazosin].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20020701

Title: Doxazosin, an inferior antihypertensive agent?

Journal: Journal of human hypertension 20020601

Title: [Chiral separation and preparation of three new antagonists of alpha 1-adrenoceptors by chiral mobile phase HPLC].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020601

Title: Reversible ageusia induced by losartan: a case report.

Journal: European journal of neurology 20020501

Title: A postmarketing, open-label study to evaluate the tolerability and effectiveness of replacing standard-formulation doxazosin with doxazosin in the gastrointestinal therapeutic system formulation in adult patients with hypertension.

Journal: Clinical therapeutics 20020501

Title: Double-blind, placebo-controlled crossover comparison of five classes of antihypertensive drugs.

Journal: Journal of hypertension 20020401

Title: [Doxazosin, of modified liberation, in hemodialyzed patients].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20020401

Title: Reduction of the soluble cyclic GMP vasorelaxing system in the vascular wall of stroke-prone spontaneously hypertensive rats: effect of the alpha1 -receptor blocker doxazosin.

Journal: Journal of hypertension 20020301

Title: Interaction of digoxin with antihypertensive drugs via MDR1.

Journal: Life sciences 20020215

Title: Stability-indicating methods for the determination of doxazosin mezylate and celecoxib.

Journal: Journal of pharmaceutical and biomedical analysis 20020201

Title: Flow injection analysis of doxazosin mesylate using UV-detection.

Journal: Journal of pharmaceutical and biomedical analysis 20020201

Title: Combined oral therapy with sildenafil and doxazosin for the treatment of non-organic erectile dysfunction refractory to sildenafil monotherapy.

Journal: International journal of impotence research 20020201

Title: Double-blind, crossover, comparative study of doxazosin and enalapril in the treatment of hypertension in renal transplant patients under cyclosporine immunosuppression.

Journal: Transplantation proceedings 20020201

Title: Quinazoline-derived alpha1-adrenoceptor antagonists induce prostate cancer cell apoptosis via an alpha1-adrenoceptor-independent action.

Journal: Cancer research 20020115

Title: Relationship between arterial distensibility and low-frequency power spectrum of blood pressure in spontaneously hypertensive rats.

Journal: Journal of cardiovascular pharmacology 20020101

Title: Influence of the alpha-1-adrenergic receptor blocker doxazosin on exercise-induced hyperkalemia in hemodialysis patients.

Journal: Kidney & blood pressure research 20020101

Title: Observational multicentric trial performed with doxazosin: evaluation of sexual effects on patients with diagnosed benign prostatic hyperplasia.

Journal: Urologia internationalis 20020101

Title: Stroke associated with alpha blocker therapy for benign prostatic hypertrophy.

Journal: Journal of the National Medical Association 20020101

Title: Effect of doxazosin on rat urinary bladder function after partial outlet obstruction.

Journal: Neurourology and urodynamics 20020101

Title: Low-dose doxazosin improved aortic stiffness and endothelial dysfunction as measured by noninvasive evaluation.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20020101

Title: The choice of antihypertensive drugs in patients with erectile dysfunction.

Journal: Current medical research and opinion 20020101

Title: Doxazosin and congestive heart failure.

Journal: Congestive heart failure (Greenwich, Conn.) 20020101

Title: Alpha1-adrenoceptor antagonists radiosensitize prostate cancer cells via apoptosis induction.

Journal: Anticancer research 20020101

Title: Differential actions of naftopidil, doxazosin and nifedipine on platelet thromboxane generation and platelet-derived growth factor efflux in vitro.

Journal: Platelets 20020101

Title: Alpha blockade in preoperative preparation of patients with pheochromocytomas.

Journal: International surgery 20020101

Title: [Policy of antihypertensive therapy in arterial hypertension in the elderly. II].

Journal: Klinicheskaia meditsina 20020101

Title: Apoptotic and proliferative index after Alpha-1-adrenoceptor antagonist and/or finasteride treatment in benign prostatic hyperplasia.

Journal: Urologia internationalis 20020101

Title: Success and predictors of blood pressure control in diverse North American settings: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT).

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20020101

Title: [Tonocardin in complex treatment of diabetes mellitus concurrent with hypertension].

Journal: Terapevticheskii arkhiv 20020101

Title: [Drug therapy of spastic disorder of urine outflow in patients with spinal injury and spinal cord injury].

Journal: Likars'ka sprava 20020101

Title: Lower urinary tract symptoms, pain and quality of life assessment in chronic non-bacterial prostatitis patients treated with alpha-blocking agent doxazosin; versus placebo.

Journal: International urology and nephrology 20020101

Title: Terazosin, doxazosin, and prazosin: current clinical experience.

Journal: Urology 20011201

Title: Doxazosin and congestive heart failure.

Journal: Journal of the American College of Cardiology 20011101

Title: Doxazosin for the management of hypertension: implications of the findings of the ALLHAT trial.

Journal: American journal of hypertension 20011101

Title: Warning for antihypertensive drug?

Journal: Lancet (London, England) 20011006

Title: [Effect of doxazosin on postural changes in blood pressure using a multibiomedical recorder].

Journal: Nihon Jinzo Gakkai shi 20011001

Title: Heart lines. Cardura update.

Journal: Harvard heart letter : from Harvard Medical School 20010901

Title: Doxazosin reduces prevalence of small dense low density lipoprotein and remnant-like particle cholesterol levels in nondiabetic and diabetic hypertensive patients.

Journal: American journal of hypertension 20010901

Title: Discontinuation of alpha-blockade after initial treatment with finasteride and doxazosin in men with lower urinary tract symptoms and clinical evidence of benign prostatic hyperplasia.

Journal: Urology 20010801

Title: Apoptotic activity of doxazosin on prostate stroma in vitro is mediated through an autocrine expression of TGF-beta1.

Journal: The Prostate 20010801

Title: Role of alpha1-blockade in congenital long QT syndrome: investigation by exercise stress test.

Journal: Japanese circulation journal 20010701

Title: [Doxazosin and soluble guanylate cyclase in a rat model of hypertension].

Journal: Revista espanola de cardiologia 20010701

Title: Antihypertensive effect of alpha- and beta-adrenergic blockade in obese and lean hypertensive subjects.

Journal: American journal of hypertension 20010701

Title: Safety and availability of doxazosin in treating hypertensive patients with chronic renal failure.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20010701

Title: On call. I'm a 76-year-old man with an enlarged prostate. I've been taking Cardura and it's helped a lot, but my doctor stopped it because he said a study found the drug could cause heart failure. Now I'm getting up three or four times a night again. Is Cadura safe?

Journal: Harvard men's health watch 20010701

Title: Structure-activity studies for a novel series of bicyclic substituted hexahydrobenz[e]isoindole alpha1A adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia.

Journal: Journal of medicinal chemistry 20010607

Title: US FDA weighs options for warning on antihypertensive drug.

Journal: Lancet (London, England) 20010602

Title: Voltammetric determination of doxazosin in tablets using rotating platinum electrode.

Journal: Journal of pharmaceutical and biomedical analysis 20010601

Title: Low-dose alpha/beta blockade in the treatment of essential hypertension.

Journal: American journal of hypertension 20010601

Title: [Alpha-blockers in therapy of arterial hypertension. No longer the drug of first choice].

Journal: MMW Fortschritte der Medizin 20010531

Title: Doxazosin inhibits monocyte chemotactic protein 1-directed migration of human monocytes.

Journal: Journal of cardiovascular pharmacology 20010501

Title: Effect of antihypertensive therapy on renal artery structure in type 2 diabetic rats with hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20010501

Title: Initiation of nonselective alpha1-antagonist therapy and occurrence of hypotension-related adverse events among men with benign prostatic hyperplasia: a retrospective cohort study.

Journal: Clinical therapeutics 20010501

Title: Baseline characteristics of the diabetic participants in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Diabetes care 20010401

Title: Reduced heat shock proteins: a mechanism to explain higher cardiovascular events associated with doxazosin.

Journal: Journal of human hypertension 20010401

Title: Doxazosin, an alpha1-adrenergic antihypertensive agent, decreases serum oxidized LDL.

Journal: American journal of hypertension 20010301

Title: Doxazosin, an alpha1-adrenoceptor antagonist, inhibits serotonin-induced shape change in human platelets.

Journal: Journal of human hypertension 20010301

Title: Reduced heat shock proteins--a mechanism to explain higher cardiovascular events associated with doxazosin.

Journal: Journal of human hypertension 20010301

Title: The cost-effectiveness of doxazosin for the treatment of hypertension in type II diabetic patients in the UK and Italy.

Journal: International journal of clinical practice 20010301

Title: Apoptotic regression of prostatic tissue induced by short-term doxazosin treatment in benign prostatic hyperplasia.

Journal: Archivos espanoles de urologia 20010301

Title: [Long-term therapy of benign prostatic hyperplasia. Our experience].

Journal: Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20010301

Title: Operational aspects of terminating the doxazosin arm of The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal: Controlled clinical trials 20010201

Title: A combined analysis of double-blind trials of the efficacy and tolerability of doxazosin-gastrointestinal therapeutic system, doxazosin standard and placebo in patients with benign prostatic hyperplasia.

Journal: BJU international 20010201

Title: Renal hemodynamic effects of captopril and doxazosin during slight physical activity in hypertensive patients with type-1 diabetes mellitus.

Journal: Kidney & blood pressure research 20010101

Title: A quantitative analysis of antagonism and inverse agonism at wild-type and constitutively active hamster alpha1B-adrenoceptors.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010101

Title: pH-mediated field-amplified sample stacking of pharmaceutical cations in high-ionic strength samples.

Journal: Electrophoresis 20010101

Title: Discontinuation of alpha-blockade after initial treatment with finasteride and doxazosin for bladder outlet obstruction.

Journal: Urologia internationalis 20010101

Title: Low-dose ACE with alpha- or beta-adrenergic receptor inhibitors have beneficial SHR cardiovascular effects.

Journal: Journal of cardiovascular pharmacology and therapeutics 20010101

Title: Doxazosin added to single-drug therapy in hypertensive patients with benign prostatic hypertrophy.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20010101

Title: [Doksazozin 'Cardura' in acute urinary retention caused by benign prostatic hyperplasia].

Journal: Urologiia (Moscow, Russia : 1999) 20010101

Title: A comparison of selected antihypertensives and the use of conventional vs ambulatory blood pressure in the detection and treatment of hypertension.

Journal: Cardiology 20010101

Title: Efficacy and tolerability of drugs for treatment of benign prostatic hyperplasia.

Journal: International urology and nephrology 20010101

Title: Quality-of-life assessment in patients with benign prostatic hyperplasia: effects of various interventions.

Journal: PharmacoEconomics 20010101

Title: Clinical significance of alpha1-adrenoceptor selectivity in the management of benign prostatic hyperplasia.

Journal: International urology and nephrology 20010101

Title: Suppression of human prostate cancer cell growth by alpha1-adrenoceptor antagonists doxazosin and terazosin via induction of apoptosis.

Journal: Cancer research 20000815

Title: Alpha-blockers and congestive heart failure: early termination of an arm of the ALLHAT trial.

Journal: Cleveland Clinic journal of medicine 20000601

Title: Characterization of human recombinant alpha(2A)-adrenoceptors expressed in Chinese hamster lung cells using intracellular Ca(2+) changes: evidence for cross-talk between recombinant alpha(2A)- and native alpha(1)-adrenoceptors.

Journal: British journal of pharmacology 20000401

Title: Platelet alpha2-adrenoceptor alterations in patients with essential hypertension are normalized after treatment with doxazosin but not propranolol.

Journal: Journal of hypertension 20000201

Title: Effect of alpha1-adrenoceptor blockade on coronary vasodilator reserve in cardiac syndrome X.

Journal: Journal of cardiovascular pharmacology 19991001

Title: Alpha 1-adrenoceptor antagonists terazosin and doxazosin induce prostate apoptosis without affecting cell proliferation in patients with benign prostatic hyperplasia.

Journal: The Journal of urology 19990601

Title: A meta-analysis on the efficacy and tolerability of alpha1-adrenoceptor antagonists in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction.

Journal: European urology 19990101

Title: Doxazosin GITS compared with doxazosin standard and placebo in patients with mild hypertension.

Journal: Blood pressure 19990101

Title: Stress urinary incontinence due to prescription medications: alpha-blockers and angiotensin converting enzyme inhibitors.

Journal: Obstetrics and gynecology 19980501

Title: Pharmacology of tamsulosin: saturation-binding isotherms and competition analysis using cloned alpha 1-adrenergic receptor subtypes.

Journal: The Prostate 19970915

Title: Prostatic alpha 1-adrenoceptors and uroselectivity.

Journal: The Prostate 19970215

Title: Long-term effects on sexual function of five antihypertensive drugs and nutritional hygienic treatment in hypertensive men and women. Treatment of Mild Hypertension Study (TOMHS).

Journal: Hypertension (Dallas, Tex. : 1979) 19970101

Title: Micturition in conscious rats with and without bladder outlet obstruction: role of spinal alpha 1-adrenoceptors.

Journal: British journal of pharmacology 19960301

Title: Blood pressure and blood glucose levels during a cross-over treatment of doxazosin, moduretic and amlodipine in hypertensive patients.

Journal: The Kobe journal of medical sciences 19960201

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Title: Doxazosin versus nitrendipine: a double-blind comparative study in patients adhering to a sodium-restricted diet.

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Title: The alpha 1-adrenergic receptor that mediates smooth muscle contraction in human prostate has the pharmacological properties of the cloned human alpha 1c subtype.

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Title: Long-term effects of doxazosin and atenolol on serum lipids and blood pressure in hypertensive smokers.

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Title: The initial hemodynamic response to newer antihypertensive agents at rest and during exercise: review of visacor, doxazosin, nisoldipine, tiapamil, perindoprilat, pinacidil, dilevalol, and carvedilol.

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Title: Doxazosin versus atenolol: a randomized comparison of calculated coronary heart disease risk reduction.

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Title: A comparison of the effects of doxazosin and alfuzosin with those of urapidil on preganglionic sympathetic nerve activity in anaesthetised cats.

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Tags:77883-43-3 Molecular Formula|77883-43-3 MDL|77883-43-3 SMILES|77883-43-3 2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine; methanesulfonic acid