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78110-38-0,MFCD00072145
Catalog No.:AA00IKEA

78110-38-0 | Aztreonam

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1g
95%
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$45.00   $32.00
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5g
95%
in stock  
$87.00   $61.00
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10g
95%
in stock  
$145.00   $102.00
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25g
95%
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$261.00   $183.00
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100g
95%
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$809.00   $567.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IKEA
Chemical Name:
Aztreonam
CAS Number:
78110-38-0
Molecular Formula:
C13H17N5O8S2
Molecular Weight:
435.4328
MDL Number:
MFCD00072145
SMILES:
C[C@H]1[C@H](NC(=O)/C(=N\OC(C(=O)O)(C)C)/c2csc(n2)N)C(=O)N1S(=O)(=O)O
NSC Number:
646279
Properties
Computed Properties
 
Complexity:
808  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
7  
XLogP3:
0.3  

Literature

Title: β-Lactam antibiotics form distinct haptenic structures on albumin and activate drug-specific T-lymphocyte responses in multiallergic patients with cystic fibrosis.

Journal: Chemical research in toxicology 20130617

Title: In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells.

Journal: The Journal of antimicrobial chemotherapy 20121101

Title: Desensitization to inhaled aztreonam lysine in an allergic patient with cystic fibrosis using a novel approach.

Journal: The Annals of pharmacotherapy 20121001

Title: [Revival of selected well-tried antibiotics. Special features of the antiinfective agents penicillin G, fosfomycin, aztreonam and colistin].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20121001

Title: A network meta-analysis of the efficacy of inhaled antibiotics for chronic Pseudomonas infections in cystic fibrosis.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20120901

Title: Early response of ceftaroline fosamic in the treatment of soft-tissue infections.

Journal: Expert review of clinical pharmacology 20120901

Title: The use of nebulised aztreonam lysine (AZLI) in aztreonam hypersensitive patients.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20120701

Title: Analysis of aztreonam-inducing proteome changes in nondividing filamentous Helicobacter pylori.

Journal: Current microbiology 20120701

Title: Inhaled antibiotics in cystic fibrosis: what's new?

Journal: Journal of the Royal Society of Medicine 20120601

Title: Necrotizing pneumonia caused by group C streptococci in a young adult.

Journal: Respiratory care 20120301

Title: Potent inhibitors of LpxC for the treatment of Gram-negative infections.

Journal: Journal of medicinal chemistry 20120126

Title: Aztreonam lysine for inhalation: new formulation of an old antibiotic.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120115

Title: In vitro combination effects of aztreonam and aminoglycoside against multidrug-resistant Pseudomonas aeruginosa in Japan.

Journal: Japanese journal of infectious diseases 20120101

Title: Decreased aztreonam susceptibility among Pseudomonas aeruginosa isolates from hospital effluent treatment system and clinical samples.

Journal: International journal of environmental health research 20120101

Title: Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies.

Journal: PloS one 20120101

Title: Inhaled aztreonam lysine for cystic fibrosis pulmonary disease-related outcomes.

Journal: The Annals of pharmacotherapy 20120101

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Therapeutic approaches to chronic cystic fibrosis respiratory infections with available, emerging aerosolized antibiotics.

Journal: Respiratory medicine 20111201

Title: Aztreonam inhalation solution for suppressive treatment of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis.

Journal: Expert review of anti-infective therapy 20111101

Title: Pseudomonas aeruginosa antibiotic susceptibility during long-term use of aztreonam for inhalation solution (AZLI).

Journal: The Journal of antimicrobial chemotherapy 20111001

Title: New Delhi metallo-β-lactamase (NDM-1): an update.

Journal: Journal of chemotherapy (Florence, Italy) 20111001

Title: Aztreonam for inhalation solution (AZLI) in patients with cystic fibrosis, mild lung impairment, and P. aeruginosa.

Journal: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20110701

Title: Aztreonam for inhalation (Cayston) for cystic fibrosis.

Journal: The Nurse practitioner 20110601

Title: Synthetic inter-species cooperation of host and virus for targeted genetic evolution.

Journal: Journal of biotechnology 20110420

Title: Aztreonam lysine for inhalation solution in cystic fibrosis: profile report.

Journal: Paediatric drugs 20110401

Title: Efficacy and safety of tigecycline monotherapy compared with vancomycin-aztreonam in the treatment of complicated skin and skin structure infections in patients from India and Taiwan.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20110401

Title: An unexpected similarity between antibiotic-resistant NDM-1 and beta-lactamase II from Erythrobacter litoralis.

Journal: Protein & cell 20110301

Title: Pharmacokinetics of aztreonam after intravenous administration in foals.

Journal: Journal of veterinary pharmacology and therapeutics 20110201

Title: Tolerability of aztreonam in patients with cell-mediated allergy to β-lactams.

Journal: International archives of allergy and immunology 20110101

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives.

Journal: European journal of medicinal chemistry 20101201

Title: An 18-month study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis.

Journal: Pediatric pulmonology 20101101

Title: Transcriptomic and phenotypic characterization of a Bacillus subtilis strain without extracytoplasmic function σ factors.

Journal: Journal of bacteriology 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: CANVAS 1: the first Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections.

Journal: The Journal of antimicrobial chemotherapy 20101101

Title: CANVAS 2: the second Phase III, randomized, double-blind study evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections.

Journal: The Journal of antimicrobial chemotherapy 20101101

Title: Integrated safety summary of CANVAS 1 and 2 trials: Phase III, randomized, double-blind studies evaluating ceftaroline fosamil for the treatment of patients with complicated skin and skin structure infections.

Journal: The Journal of antimicrobial chemotherapy 20101101

Title: Aztreonam lysine for inhalation solution: in cystic fibrosis.

Journal: Drugs 20101001

Title: Consensus statement on the adherence to Clinical and Laboratory Standards Institute (CLSI) Antimicrobial Susceptibility Testing Guidelines (CLSI-2010 and CLSI-2010-update) for Enterobacteriaceae in clinical microbiology laboratories in Taiwan.

Journal: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20101001

Title: Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100915

Title: Aztreonam for inhalation solution (Cayston) for cystic fibrosis.

Journal: The Medical letter on drugs and therapeutics 20100809

Title: Aztreonam lysine: a novel inhalational antibiotic for cystic fibrosis.

Journal: Expert review of respiratory medicine 20100801

Title: Optimal airway antimicrobial therapy for cystic fibrosis: the role of inhaled aztreonam lysine.

Journal: Expert opinion on pharmacotherapy 20100601

Title: Inhaled aztreonam.

Journal: Nature reviews. Drug discovery 20100501

Title: [Tolerance and efficacy of ceftazidime in combination with aztreonam for exacerbations of cystic fibrosis].

Journal: Revue des maladies respiratoires 20100501

Title: The catalytic efficiency (kcat/Km) of the class A beta-lactamase Toho-1 correlates with the thermal stability of its catalytic intermediate analog.

Journal: Biochimica et biophysica acta 20100401

Title: Update in cystic fibrosis 2009.

Journal: American journal of respiratory and critical care medicine 20100315

Title: Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives.

Journal: Journal of medicinal chemistry 20100114

Title: [Dissemination of the KPC carbapenemase producing Klebsiella pneumoniae in a hospital in Warsaw, Poland].

Journal: Medycyna doswiadczalna i mikrobiologia 20100101

Title: Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers.

Journal: Diagnostic microbiology and infectious disease 20091001

Title: Lack of pharmacokinetic drug interactions following concomitant administration of telavancin with aztreonam or piperacillin/tazobactam in healthy participants.

Journal: Journal of clinical pharmacology 20090701

Title: Comparison of different methods of determining beta-lactam susceptibility in clinical strains of Pseudomonas aeruginosa.

Journal: Journal of medical microbiology 20090501

Title: Efficacy and safety of inhaled aztreonam lysine for airway pseudomonas in cystic fibrosis.

Journal: Chest 20090501

Title: Piperacillin/tazobactam plus ceftazidime versus sulbactam/ampicillin plus aztreonam as empirical therapy for fever in severely neutropenic pediatric patients.

Journal: Journal of pediatric hematology/oncology 20090401

Title: [Checkerboard-plate screening synergistic aztreonam and aminoglicoside combination effects against multidrug-resistant Pseudomonas aeruginosa].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20090301

Title: A case of multidrug-resistant Salmonella enterica serovar Typhi treated with a bench to bedside approach.

Journal: Yonsei medical journal 20090227

Title: In vitro antimicrobial effects of aztreonam, colistin, and the 3-drug combination of aztreonam, ceftazidime and amikacin on metallo-beta-lactamase-producing Pseudomonas aeruginosa.

Journal: BMC infectious diseases 20090101

Title: Contribution towards developing a new semi-selective medium for Streptococcus anginosus group.

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20090101

Title: Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis.

Journal: American journal of respiratory and critical care medicine 20081101

Title: First characterization and emergence of SHV-60 in raw milk of a healthy cow in Japan.

Journal: The Journal of veterinary medical science 20081101

Title: Overview of tigecycline efficacy and safety in the treatment of complicated skin and skin structure infections - a European perspective.

Journal: Journal of chemotherapy (Florence, Italy) 20081001

Title: [Case of sepsis caused by multidrug-resistant neutropenic-phase Pseudomonas aeruginosa treated successfully with antibiotic combination therapy].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20080901

Title: What did we learn from the North American Cystic Fibrosis Conference?

Journal: Journal of the Royal Society of Medicine 20080701

Title: Molecular characterization of extended-spectrum beta-lactamases produced by clinical isolates of Enterobacter cloacae from a Teaching Hospital in China.

Journal: Japanese journal of infectious diseases 20080701

Title: First isolation of a VIM-producing Klebsiella pneumoniae from a seven-year-old child in Venezuela.

Journal: Journal of infection in developing countries 20080601

Title: [Infection treatment caused by multiple-drug-resistant Pseudomonas aeruginosa in a patient undergoing allogeneic hematopoietic stem cell transplantation].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080401

Title: Ciprofloxacin-induced Q-T interval prolongation.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080315

Title: A phase 2 study of aztreonam lysine for inhalation to treat patients with cystic fibrosis and Pseudomonas aeruginosa infection.

Journal: Pediatric pulmonology 20080101

Title: Occurrence of ESBL & Amp-C beta-lactamases & susceptibility to newer antimicrobial agents in complicated UTI.

Journal: The Indian journal of medical research 20080101

Title: Tolerability of aztreonam in patients with IgE-mediated hypersensitivity to beta-lactams.

Journal: International journal of immunopathology and pharmacology 20080101

Title: [Is aztreonam could become 'a challenger' for treatment of Gram negative infections? May be an answer from microbiological data: in vitro study including 36,485 strains of enterobacteria and Pseudomonas].

Journal: Pathologie-biologie 20071201

Title: MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 7: highly soluble and in vivo active quaternary ammonium analogue D13-9001, a potential preclinical candidate.

Journal: Bioorganic & medicinal chemistry 20071115

Title: Risk factors for and impact of infection or colonization with aztreonam-resistant Pseudomonas aeruginosa.

Journal: Infection control and hospital epidemiology 20071001

Title: Improved contamination control for a rapid phage-based rifampicin resistance test for Mycobacterium tuberculosis.

Journal: Journal of medical microbiology 20071001

Title: Development of an antimicrobial formulation for control of specimen-related contamination in phage-based diagnostic testing for tuberculosis.

Journal: Journal of applied microbiology 20071001

Title: Binding of ceftobiprole and comparators to the penicillin-binding proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.

Journal: Antimicrobial agents and chemotherapy 20070701

Title: [Cefepime and aztreonam shortages: we've run out of ammo].

Journal: Enfermedades infecciosas y microbiologia clinica 20070501

Title: Comparative in vitro killing of carbapenems and aztreonam against Klebsiella pneumoniae producing VIM-1 metallo-beta-lactamase.

Journal: International journal of antimicrobial agents 20070301

Title: Treatment of infections caused by metallo-beta-lactamase-producing Pseudomonas aeruginosa in the Calgary Health Region.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20070201

Title: Successful treatment of Pasteurella multocida meningitis with aztreonam.

Journal: Scandinavian journal of infectious diseases 20070101

Title: Molecular epidemiology of clinical Pseudomonas aeruginosa isolates carrying IMP-1 metallo-beta-lactamase gene in a University Hospital in Turkey.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20070101

Title: [Imipenem resistance in Gram-negative rods and its consumption between 1999 and 2005].

Journal: Medycyna doswiadczalna i mikrobiologia 20070101

Title: MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: exploration of aromatic substituents.

Journal: Bioorganic & medicinal chemistry 20061215

Title: Transient neutrophilic thrombophagocytosis associated with Citrobacter freundii septicemia.

Journal: Archives of pathology & laboratory medicine 20061201

Title: Occurrence of extended-spectrum beta-lactamases in Enterobacteriaceae isolated from hospitalized patients in Curitiba, southern Brazil.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20061201

Title: Effects of beta-lactam antibiotics and L-arginine in the treatment of experimental sepsis in rats.

Journal: International journal of antimicrobial agents 20061101

Title: Nosocomial infection with cephalosporin-resistant Klebsiella pneumoniae is not associated with increased mortality.

Journal: Infection control and hospital epidemiology 20060901

Title: High concentration and bioactivity of vancomycin and aztreonam eluted from Simplex cement spacers in two-stage revision of infected hip implants: a study of 46 patients at an average follow-up of 107 days.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20060801

Title: Microbiology, safety, and pharmacokinetics of aztreonam lysinate for inhalation in patients with cystic fibrosis.

Journal: Pediatric pulmonology 20060701

Title: Quantitation of Bacillus clausii in biological samples by real-time polymerase chain reaction.

Journal: Journal of microbiological methods 20060601

Title: Impact of linezolid on economic outcomes and determinants of cost in a clinical trial evaluating patients with MRSA complicated skin and soft-tissue infections.

Journal: The Annals of pharmacotherapy 20060601

Title: Assessing the protonation state of drug molecules: the case of aztreonam.

Journal: Journal of medicinal chemistry 20060601

Title: Cefepime vs. Ampicillin/Sulbactam and Aztreonam as antibiotic prophylaxis in neurosurgical patients with external ventricular drain: result of a prospective randomized controlled clinical trial.

Journal: Journal of clinical pharmacy and therapeutics 20060601

Title: [Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2004). I. Susceptibility distribution].

Journal: The Japanese journal of antibiotics 20060601

Title: Treatment of culture-negative skull base osteomyelitis.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20060201

Title: [The combination effects of antibacterial agents against clinical isolated multiple-drug resistant Pseudomonas aeruginosa].

Journal: The Japanese journal of antibiotics 20060201

Title: Molecular dynamics simulations of class C beta-lactamase from Citrobacter freundii: insights into the base catalyst for acylation.

Journal: Biochemistry 20060117

Title: Erythroderma due to aztreonam and clindamycin.

Journal: Journal of investigational allergology & clinical immunology 20060101

Title: A simple phenotypic method for differentiation between acquired and chromosomal AmpC beta-lactamases in Escherichia coli.

Journal: Enfermedades infecciosas y microbiologia clinica 20060101

Title: Successful treatment of Pasteurella multocida meningitis with aztreonam.

Journal: Scandinavian journal of infectious diseases 20060101

Title: In vitro activity of beta-lactam antimicrobial agents in combination with aztreonam tested against metallo-beta-lactamase-producing Pseudomonas aeruginosa and Acinetobacter baumannii.

Journal: Journal of chemotherapy (Florence, Italy) 20051201

Title: A deficiency in S-adenosylmethionine synthetase interrupts assembly of the septal ring in Escherichia coli K-12.

Journal: Molecular microbiology 20051101

Title: The efficacy and safety of tigecycline in the treatment of skin and skin-structure infections: results of 2 double-blind phase 3 comparison studies with vancomycin-aztreonam.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20050901

Title: Bacterial prostatitis due to Pseudomonas aeruginosa harbouring the blaVIM-2 metallo-{beta}-lactamase gene from Saudi Arabia.

Journal: The Journal of antimicrobial chemotherapy 20050901

Title: Efficacy and safety of tigecycline monotherapy compared with vancomycin plus aztreonam in patients with complicated skin and skin structure infections: Results from a phase 3, randomized, double-blind trial.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20050901

Title: Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.

Journal: Journal of pharmaceutical sciences 20050701

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Continuous infusion beta-lactams for intensive care unit pulmonary infections.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20050501

Title: Comprehensive in vitro evaluation of cefepime combined with aztreonam or ampicillin/sulbactam against multi-drug resistant Pseudomonas aeruginosa and Acinetobacter spp.

Journal: International journal of antimicrobial agents 20050501

Title: Structure-activity relationships of bivalent aminoglycosides and evaluation of their microbiological activities.

Journal: Bioorganic & medicinal chemistry letters 20050415

Title: Pilot study for the development of a new campylobacter selective medium at 37 degrees C using aztreonam.

Journal: Journal of clinical pathology 20050401

Title: Stability of aztreonam in AZACTAM.

Journal: Farmaco (Societa chimica italiana : 1989) 20050101

Title: [The occurrence and characterisation of oxy-imino-beta-lactams resistant strains among Salmonella enterica subsp. enterica isolated in Poland].

Journal: Medycyna doswiadczalna i mikrobiologia 20050101

Title: Beta-lactam susceptibilities and prevalence of ESBL-producing isolates among more than 5000 European Enterobacteriaceae isolates.

Journal: International journal of antimicrobial agents 20041201

Title: In vitro activities of beta-lactam antibiotics alone and in combination with sulbactam against Gram-negative bacteria.

Journal: International journal of antimicrobial agents 20040601

Title: In vitro activities of antibiotic combinations against clincal isolates of Pseudomonas aeruginosa.

Journal: The Kaohsiung journal of medical sciences 20040601

Title: Aztreonam.

Journal: Indian pediatrics 20040401

Title: The combination of aztreonam and cefozopran against Stenotrophomonas maltophilia.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20040201

Title: Pharmacokinetic interactions of ceftazidime, imipenem and aztreonam with amikacin in healthy volunteers.

Journal: International journal of antimicrobial agents 20040201

Title: Using nanoparticle optics assay for direct observation of the function of antimicrobial agents in single live bacterial cells.

Journal: Biochemistry 20040113

Title: Inhaled antibiotics.

Journal: Pediatric pulmonology. Supplement 20040101

Title: Contemporary in vitro synergy rates for aztreonam combined with newer fluoroquinolones and beta-lactams tested against gram-negative bacilli.

Journal: Diagnostic microbiology and infectious disease 20031101

Title: Antimicrobial spectrum of activity for meropenem and nine broad spectrum antimicrobials: report from the MYSTIC Program (2002) in North America.

Journal: Diagnostic microbiology and infectious disease 20030901

Title: Sepsis in a renal transplant recipient due to Citrobacter braakii.

Journal: Southern medical journal 20030801

Title: Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients.

Journal: American journal of clinical oncology 20030601

Title: Piperacillin plus aztreonam for treatment of neutropenic fever.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20030601

Title: Effect of basic amino acids on susceptibility to carbapenems in clinical Pseudomonas aeruginosa isolates.

Journal: International journal of medical microbiology : IJMM 20030601

Title: In vitro synergy studies using aztreonam and fluoroquinolone combinations against six species of Gram-negative bacilli.

Journal: Chemotherapy 20030501

Title: Spectrophotometric and fluorimetric determination of aztreonam in bulk and dosage forms.

Journal: Journal of pharmaceutical and biomedical analysis 20030326

Title: An approach for the evaluation of synergy between antimicrobials.

Journal: International journal of antimicrobial agents 20030301

Title: Aztreonam treatment of Pasteurella multocida cellulitis and bacteremia.

Journal: The Annals of pharmacotherapy 20030301

Title: Utilization of extended-spectrum beta-lactamase (ESBL) detection systems in microbiology laboratories: survey of Connecticut hospitals from 1998-2002.

Journal: Connecticut medicine 20030301

Title: Continuation of a randomized, double-blind, multicenter study of linezolid versus vancomycin in the treatment of patients with nosocomial pneumonia.

Journal: Clinical therapeutics 20030301

Title: A dynamic structure for the acyl-enzyme species of the antibiotic aztreonam with the Citrobacter freundii beta-lactamase revealed by infrared spectroscopy and molecular dynamics simulations.

Journal: Biochemistry 20030225

Title: Differential modulation of the induction of inflammatory mediators by antibiotics in mouse macrophages in response to viable Gram-positive and Gram-negative bacteria.

Journal: Journal of endotoxin research 20030101

Title: [Characteristics and clinical value of extended-spectrum beta-lactamases].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

Title: [In vitro antibacterial activity and beta-lactamase stability of meropenem].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101

Title: Simple intravenous antimicrobial desensitization method for pediatric patients.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020815

Title: Detection of extended spectrum beta-lactamases in the routine clinical microbiology laboratory.

Journal: Pathology 20020801

Title: Secondary-site mutation restores the transport defect caused by the transmembrane domain mutation of the xenobiotic transporter MexB in Pseudomonas aeruginosa.

Journal: Biochemical and biophysical research communications 20020329

Title: Severe cellulitis/myositis caused by Stenotrophomonas maltophilia.

Journal: The Annals of pharmacotherapy 20020101

Title: In vitro synergy testing of levofloxacin, ofloxacin, and ciprofloxacin in combination with aztreonam, ceftazidime, or piperacillin against Pseudomonas aeruginosa.

Journal: Diagnostic microbiology and infectious disease 20020101

Title: Susceptibility of Streptococcus mutans and Streptococcus sobrinus to cell wall inhibitors and development of a novel selective medium for S. sobrinus.

Journal: Caries research 20020101

Title: Mycotic aneurysm of the descending thoracic aorta caused by Pseudomonas aeruginosa in a solid organ transplant recipient: case report and review.

Journal: Surgical infections 20020101

Title: Distribution of the Escherichia coli structural maintenance of chromosomes (SMC)-like protein MukB in the cell.

Journal: Molecular microbiology 20011201

Title: Effects of anti-tumour necrosis factor, interleukin-10 and antibiotic therapy in the indometacin-induced bowel inflammation rat model.

Journal: Alimentary pharmacology & therapeutics 20011101

Title: Traveler's diarrhea.

Journal: Gastroenterology clinics of North America 20010901

Title: Neonatal intensive care unit outbreak caused by a strain of Klebsiella oxytoca resistant to aztreonam due to overproduction of chromosomal beta-lactamase.

Journal: The Journal of hospital infection 20010801

Title: Pharmacokinetics and pharmacodynamics of aztreonam and tobramycin in hospitalized patients.

Journal: Clinical therapeutics 20010801

Title: Variations in the prevalence of strains expressing an extended-spectrum beta-lactamase phenotype and characterization of isolates from Europe, the Americas, and the Western Pacific region.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010515

Title: Beta-lactam antibiotic-mediated changes in platelet reactivity and vascular endothelial functions.

Journal: Pharmacology & toxicology 20010501

Title: SHV-27, a novel cefotaxime-hydrolysing beta-lactamase, identified in Klebsiella pneumoniae isolates from a Brazilian hospital.

Journal: The Journal of antimicrobial chemotherapy 20010401

Title: Treatment of nosocomial postoperative pneumonia in cancer patients: a prospective randomized study.

Journal: Annals of surgical oncology 20010301

Title: In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin and fusidic acid against Borrelia burgdorferi.

Journal: International journal of antimicrobial agents 20010301

Title: Emergence of cephem- and aztreonam-high-resistant Neisseria gonorrhoeae that does not produce beta-lactamase.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20010301

Title: Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter study.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010201

Title: The effect of acetazolamide on the kinetics of four newer beta-lactams in the aqueous humor.

Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20010201

Title: Activity of cefepime, cefotaxime, ceftazidime, and aztreonam against extended-spectrum-producing isolates of Klebsiella pneumoniae and Escherichia coli from Chilean hospitals.

Journal: Diagnostic microbiology and infectious disease 20010101

Title: beta-Lactam-susceptibility patterns of Plesiomonas shigelloides strains: importance of inoculum and medium.

Journal: Scandinavian journal of infectious diseases 20010101

Title: In vitro susceptibility of Stenotrophomonas maltophilia to various antimicrobial combinations.

Journal: Diagnostic microbiology and infectious disease 20010101

Title: Comparison of aztreonam against other antibiotics used in urinary tract infections.

Journal: Journal of Ayub Medical College, Abbottabad : JAMC 20010101

Title: Contribution of beta-lactamases to beta-lactam susceptibilities of susceptible and multidrug-resistant Mycobacterium tuberculosis clinical isolates.

Journal: Antimicrobial agents and chemotherapy 19980601

Title: Comparative epileptogenic properties of two monobactam derivatives in C57, Swiss and DBA/2 mice.

Journal: The Journal of antimicrobial chemotherapy 19960901

Title: Cefotetan disodium-induced hemolytic anemia.

Journal: The Annals of pharmacotherapy 19920201

Title: Epitope analysis of aztreonam by antiaztreonam monoclonal antibodies and possible consequences in beta-lactams hypersensitivity.

Journal: International archives of allergy and immunology 19920101

Title: Sensitization to aztreonam and cross-reactivity with other beta-lactam antibiotics in high-risk patients with cystic fibrosis.

Journal: The Journal of allergy and clinical immunology 19910101

Title: Aztreonam in the treatment of gram-negative bacterial meningitis.

Journal: Reviews of infectious diseases 19910101

Title: Evaluation of the immunologic cross-reactivity of aztreonam in patients with cystic fibrosis who are allergic to penicillin and/or cephalosporin antibiotics.

Journal: Reviews of infectious diseases 19910101

Title: In-vitro activity of seventeen antimicrobial compounds against seven species of mycobacteria.

Journal: The Journal of antimicrobial chemotherapy 19881201

Title: Acute renal failure, skin rash, and eosinophilia associated with aztreonam.

Journal: American journal of nephrology 19880101

Title: Broth microdilution testing of susceptibilities to 30 antimicrobial agents of Mycobacterium avium strains from patients with acquired immune deficiency syndrome.

Journal: Antimicrobial agents and chemotherapy 19871001

Title: Azthreonam in the treatment of urinary tract infection: evaluation of efficacy, renal effects and nephrotoxicity.

Journal: Drugs under experimental and clinical research 19870101

Title: Comparative evaluation of aztreonam in therapy for experimental bacterial meningitis and cerebritis.

Journal: Reviews of infectious diseases 19850101

Title: Aztreonam therapy for complicated urinary tract infections caused by multidrug-resistant bacteria.

Journal: Reviews of infectious diseases 19850101

Title: Kobayashi Y, et al. Synergy with aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa isolated from blood. J Antimicrob Chemother. 1992 Dec;30(6):871-2.

Title: Guay DR, et al. Aztreonam, a new monobactam antimicrobial. Clin Pharm. 1985 Sep-Oct;4(5):516-26.

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Tags:78110-38-0 Molecular Formula|78110-38-0 MDL|78110-38-0 SMILES|78110-38-0 Aztreonam