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78416-81-6,MFCD01076563
Catalog No.:AA0053GP

78416-81-6 | Trequinsin hydrochloride

Pack Size
Purity
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Price(USD)
Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
- +
5mg
≥98%
in stock  
$276.00   $193.00
- +
10mg
≥98%
in stock  
$398.00   $278.00
- +
50mg
≥97%(HPLC)
in stock  
$1,807.00   $1,265.00
- +
100mg
≥97%(HPLC)
in stock  
$2,974.00   $2,082.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0053GP
Chemical Name:
Trequinsin hydrochloride
CAS Number:
78416-81-6
Molecular Formula:
C24H28ClN3O3
Molecular Weight:
441.9504
MDL Number:
MFCD01076563
SMILES:
COc1cc2c(cc1OC)CCn1c2cc(=Nc2c(C)cc(cc2C)C)n(c1=O)C.Cl
Properties
Computed Properties
 
Complexity:
709  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  

Literature

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: The pharmacology of two novel long-acting phosphodiesterase 3/4 inhibitors, RPL554 [9,10-dimethoxy-2(2,4,6-trimethylphenylimino)-3-(n-carbamoyl-2-aminoethyl)-3,4,6,7-tetrahydro-2H-pyrimido[6,1-a]isoquinolin-4-one] and RPL565 [6,7-dihydro-2-(2,6-diisopropylphenoxy)-9,10-dimethoxy-4H-pyrimido[6,1-a]isoquinolin-4-one].

Journal: The Journal of pharmacology and experimental therapeutics 20060801

Title: Peripheral participation of the phosphodiesterase 3 on formalin-evoked nociception.

Journal: European journal of pharmacology 20050905

Title: Effects of phosphodiesterase inhibitors on spontaneous nuclear maturation and cAMP concentrations in bovine oocytes.

Journal: Theriogenology 20031201

Title: Control of renin secretion from rat juxtaglomerular cells by cAMP-specific phosphodiesterases.

Journal: Circulation research 20020517

Title: Phosphodiesterase inhibitors cause relaxation of the internal anal sphincter in vitro.

Journal: Diseases of the colon and rectum 20020401

Title: Activation of protein kinase A by nitric oxide in cultured dorsal root ganglion neurites of the rat, examined by a fluorescence probe, ARII.

Journal: Neuroscience letters 20020118

Title: Modulation of eotaxin formation and eosinophil migration by selective inhibitors of phosphodiesterase type 4 isoenzyme.

Journal: British journal of pharmacology 20010901

Title: The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides.

Journal: The Journal of biological chemistry 20000929

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