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78606-80-1,MFCD00211214
Catalog No.:AA00G34Z

78606-80-1 | 5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER

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1mg
≥95%
in stock  
$82.00   $57.00
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5mg
≥95%
in stock  
$356.00   $249.00
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10mg
≥95%
in stock  
$625.00   $437.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G34Z
Chemical Name:
5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER
CAS Number:
78606-80-1
Molecular Formula:
C8H16O5
Molecular Weight:
192.2096
MDL Number:
MFCD00211214
SMILES:
OC[C@H]([C@H](CCCC(=O)OC)O)O
Properties
Computed Properties
 
Complexity:
148  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  
XLogP3:
-1.2  

Literature

Title: Treatment of Lipoxin A(4) and its analogue on low-dose endotoxin induced preeclampsia in rat and possible mechanisms.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20121201

Title: BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats.

Journal: Resuscitation 20120701

Title: Annexin 1 exerts anti-nociceptive effects after peripheral inflammatory pain through formyl-peptide-receptor-like 1 in rat dorsal root ganglion.

Journal: British journal of anaesthesia 20111201

Title: Lipoxin A4 and its analog suppress hepatocellular carcinoma via remodeling tumor microenvironment.

Journal: Cancer letters 20111001

Title: Lipoxin A(4) attenuates zymosan-induced arthritis by modulating endothelin-1 and its effects.

Journal: British journal of pharmacology 20101001

Title: Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis.

Journal: Molecular cancer therapeutics 20100801

Title: Lipoxin A(4) metabolites/analogues from two commercial sources have no effects on TNF-alpha-mediated priming or activation through the neutrophil formyl peptide receptors.

Journal: Scandinavian journal of immunology 20091001

Title: Ying Chen, et al. Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis. Mol Cancer Ther. 2010 Aug;9(8):2164-74.

Title: Qiong-Feng Chen, et al. BML-111, a Lipoxin Receptor Agonist, Protects Against Acute Injury via Regulating the Renin Angiotensin-Aldosterone System. Prostaglandins Other Lipid Mediat. 2019 Feb;140:9-17.

Title: T H Lee, et al. Inhibition of Leukotriene B4-induced Neutrophil Migration by Lipoxin A4: Structure-Function Relationships. Biochem Biophys Res Commun. 1991 Nov 14;180(3):1416-21.

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Tags:78606-80-1 Molecular Formula|78606-80-1 MDL|78606-80-1 SMILES|78606-80-1 5(S),6(R),7-TRIHYDROXYHEPTANOIC ACID, METHYL ESTER