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787-93-9,MFCD00865288
Catalog No.:AA005DEW

787-93-9 | 4-Amino-N-(2,6-dimethylphenyl)benzamide

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Purity
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250mg
95%
1 week  
$106.00   $74.00
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1g
95%
1 week  
$283.00   $198.00
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5g
95%
1 week  
$848.00   $594.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005DEW
Chemical Name:
4-Amino-N-(2,6-dimethylphenyl)benzamide
CAS Number:
787-93-9
Molecular Formula:
C15H16N2O
Molecular Weight:
240.3003
MDL Number:
MFCD00865288
SMILES:
O=C(c1ccc(cc1)N)Nc1c(C)cccc1C
Properties
Properties
 
Form:
Solid  
MP:
220 - 222 °C  
Storage:
-20 ℃;Inert atmosphere;  

Computed Properties
 
Complexity:
274  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
2.2  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ELILILLY&CO-US4642379,1987,A

[2]Robertson;Leander;Lawson;Beedle;Clark;Potts;Parli[JournalofMedicinalChemistry,1987,vol.30,#10,p.1742-1746]

[1]Vamecq,Joseph;Lambert,Didier;Poupaert,JacquesH.;Masereel,Bernard;Stables,JamesP.[JournalofMedicinalChemistry,1998,vol.41,#18,p.3307-3313]

[2]Zhang,Liandi;Xin,Minhang;Shen,Han;Wen,Jun;Tang,Feng;Tu,Chongxing;Zhao,Xinge;Wei,Ping[BioorganicandMedicinalChemistryLetters,2014,vol.24,#15,p.3486-3492]

[3]Bourhim,Mustapha;Poupaert,JacquesH.;Stables,JamesP.;Vallee,Louis;Vamecq,Joseph[Arzneimittel-Forschung/DrugResearch,1999,vol.49,#2,p.81-87]

[1]Vamecq,Joseph;Lambert,Didier;Poupaert,JacquesH.;Masereel,Bernard;Stables,JamesP.[JournalofMedicinalChemistry,1998,vol.41,#18,p.3307-3313]

[1]Bourhim,Mustapha;Poupaert,JacquesH.;Stables,JamesP.;Vallee,Louis;Vamecq,Joseph[Arzneimittel-Forschung/DrugResearch,1999,vol.49,#2,p.81-87]

[1]Bourhim,Mustapha;Poupaert,JacquesH.;Stables,JamesP.;Vallee,Louis;Vamecq,Joseph[Arzneimittel-Forschung/DrugResearch,1999,vol.49,#2,p.81-87]

Literature

Title: Nonlinear mixed effects pharmacokinetic/pharmacodynamic analysis of the anticonvulsant ameltolide (LY201116) in a canine seizure model.

Journal: Journal of veterinary pharmacology and therapeutics 20081201

Title: Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.

Journal: Journal of medicinal chemistry 20051006

Title: Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons.

Journal: The Journal of biological chemistry 20040430

Title: Anticonvulsant phenytoinergic pharmacophores and anti-HIV activity--preliminary evidence for the dual requirement of the 4-aminophthalimide platform and the N-(1-adamantyl) substitution for antiviral properties.

Journal: Life sciences 19980101

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