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78859-42-4,MFCD00043258
Catalog No.:AA008NIN

78859-42-4 | 5'-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride

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5mg
2 weeks  
$179.00   $125.00
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10mg
2 weeks  
$250.00   $175.00
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25mg
2 weeks  
$429.00   $300.00
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50mg
2 weeks  
$608.00   $425.00
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100mg
2 weeks  
$965.00   $675.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008NIN
Chemical Name:
5'-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride
CAS Number:
78859-42-4
Molecular Formula:
C17H17ClFN5O7S
Molecular Weight:
489.8626
MDL Number:
MFCD00043258
SMILES:
O[C@@H]1[C@@H](COC(=O)c2ccc(cc2)S(=O)(=O)F)O[C@H]([C@@H]1O)n1cnc2c1ncnc2N.Cl
Properties
Computed Properties
 
Complexity:
763  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  

Literature

Title: Inhibition of multidrug resistance-linked P-glycoprotein (ABCB1) function by 5'-fluorosulfonylbenzoyl 5'-adenosine: evidence for an ATP analogue that interacts with both drug-substrate-and nucleotide-binding sites.

Journal: Biochemistry 20110510

Title: Mapping of the ATP-binding domain of human fructosamine 3-kinase-related protein by affinity labelling with 5'-[p-(fluorosulfonyl)benzoyl]adenosine.

Journal: The Biochemical journal 20081201

Title: 5'-p-Fluorosulfonyl benzoyl adenosine inhibits an ecto-ATP-diphosphohydrolase in the tegument surface of Taenia crassiceps cysticerci.

Journal: Molecular and biochemical parasitology 20081201

Title: A 5'-fluorosulfonylbenzoyladenosine-based method to identify physiological substrates of a Drosophila p21-activated kinase.

Journal: Analytical biochemistry 20070915

Title: Structural characterization of the functional regions in the archaeal protein Sso7d.

Journal: Proteins 20070401

Title: Synthesis and characterization of 5'-p-fluorosulfonylbenzoyl-2' (or 3')-(biotinyl)adenosine as an activity-based probe for protein kinases.

Journal: Journal of biomolecular screening 20070201

Title: A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes.

Journal: Journal of proteome research 20061201

Title: A liquid chromatography/mass spectrometry-based method for the selection of ATP competitive kinase inhibitors.

Journal: Journal of biomolecular screening 20050801

Title: A mechanism-based cross-linker for the identification of kinase-substrate pairs.

Journal: Journal of the American Chemical Society 20040804

Title: Clopidogrel (Plavix) and cardiac surgical patients: implications for platelet function monitoring and postoperative bleeding.

Journal: Platelets 20040801

Title: Triatoma infestans apyrases belong to the 5'-nucleotidase family.

Journal: The Journal of biological chemistry 20040507

Title: Secretion of IL-2 and IFN-gamma, but not IL-4, by antigen-specific T cells requires extracellular ATP.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030315

Title: The nucleotide-binding site of human sphingosine kinase 1.

Journal: The Journal of biological chemistry 20021220

Title: 5'-p-Fluorosulfonylbenzoyl adenosine inhibits progesterone synthesis in human placental mitochondria.

Journal: Biochimica et biophysica acta 20021108

Title: The ATP-binding site of brain phosphatidylinositol 4-kinase PI4K230 as revealed by 5'-p-fluorosulfonylbenzoyladenosine.

Journal: The international journal of biochemistry & cell biology 20010301

Title: Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site.

Journal: The Journal of biological chemistry 19970502

Title: Carboxylases in de novo purine biosynthesis. Characterization of the Gallus gallus bifunctional enzyme.

Journal: Biochemistry 19941004

Title: Chemical modification of Salmonella typhimurium phosphoribosylpyrophosphate synthetase with 5'-(p-fluorosulfonylbenzoyl)adenosine. Identification of an active site histidine.

Journal: The Journal of biological chemistry 19900405

Title: Identification of the AMP binding sites of rabbit phosphofructo-1-kinase isozymes B and C.

Journal: Biochimica et biophysica acta 19881012

Title: Antibodies to the ATP-binding site of the human epidermal growth factor (EGF) receptor as specific inhibitors of EGF-stimulated protein-tyrosine kinase activity.

Journal: European journal of biochemistry 19860715

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