Home Amines 789488-77-3
789488-77-3,MFCD16817498
Catalog No.:AA00GALM

789488-77-3 | 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride

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5mg
≥99%
in stock  
$236.00   $165.00
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25mg
≥99%
in stock  
$763.00   $534.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00GALM
Chemical Name:
6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride
CAS Number:
789488-77-3
Molecular Formula:
C15H29N3O2
Molecular Weight:
283.4097
MDL Number:
MFCD16817498
SMILES:
NCCCCCC(=O)N1CCN(CC1)C(=O)CC(C)C
Properties
Computed Properties
 
Complexity:
310  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
0.3  

Literature

Title: Proteinase-activated receptor 2 blockade impairs CCL11- or allergen-induced eosinophil recruitment in experimental pleurisy.

Journal: European journal of pharmacology 20141005

Title: Antagonism of protease-activated receptor 2 protects against experimental colitis.

Journal: The Journal of pharmacology and experimental therapeutics 20120201

Title: Protease-activated receptor 2-dependent fluid secretion from airway submucosal glands by house dust mite extract.

Journal: The Journal of allergy and clinical immunology 20120201

Title: The down regulation of neutrophil oxidative metabolism by S100A8 and S100A9: implication of the protease-activated receptor-2.

Journal: Molecular immunology 20120201

Title: Expression and proinflammatory role of proteinase-activated receptor 2 in rheumatoid synovium: ex vivo studies using a novel proteinase-activated receptor 2 antagonist.

Journal: Arthritis and rheumatism 20070301

Title: Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation.

Journal: The Journal of pharmacology and experimental therapeutics 20060301

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Tags:789488-77-3 Molecular Formula|789488-77-3 MDL|789488-77-3 SMILES|789488-77-3 6-Amino-1-[4-(3-methyl-1-oxobutyl)-1-piperazinyl]-1-hexanone hydrochloride