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Title: 3D-QSAR studies on CCR2B receptor antagonists: Insight into the structural requirements of (R)-3-aminopyrrolidine series of molecules based on CoMFA/CoMSIA models.
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Title: Metabolic profiling of the protozoan parasite Entamoeba invadens revealed activation of unpredicted pathway during encystation.
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Title: Semi-quantitative analyses of metabolic systems of human colon cancer metastatic xenografts in livers of superimmunodeficient NOG mice.
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Title: Exploration of (S)-3-aminopyrrolidine as a potentially interesting scaffold for discovery of novel Abl and PI3K dual inhibitors.
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Title: Design of selective, ATP-competitive inhibitors of Akt.
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Title: Design of novel aminopyrrolidine factor Xa inhibitors from a screening hit.
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Title: Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5.
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Title: Synthesis and antimalarial activity of new amino analogues of amodiaquine.
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Title: Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae.
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Title: Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series.
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Title: New insight for fluoroquinophenoxazine derivatives as possibly new potent topoisomerase I inhibitor.
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Title: 3-Aminopyrrolidines from alpha-aminoacids: total synthesis of (+)-nemonapride from D-alanine.
Journal: The Journal of organic chemistry 20080201
Title: Palladium-mediated N-arylation of heterocyclic diamines: insights into the origin of an unusual chemoselectivity.
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Title: Enantioselective conjugate addition of a lithium ester enolate catalyzed by chiral lithium amides.
Journal: Organic letters 20061207
Title: Identification of substituted 4-aminopiperidines and 3-aminopyrrolidines as potent MCH-R1 antagonists for the treatment of obesity.
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Title: Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists.
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Title: Palladium-mediated arylation of 3-aminopiperidines and 3-aminopyrrolidines.
Journal: The Journal of organic chemistry 20041210
Title: Design and synthesis of novel biologically active thrombin receptor non-peptide mimetics based on the pharmacophoric cluster Phe/Arg/NH2 of the Ser42-Phe-Leu-Leu-Arg46 motif sequence: platelet aggregation and relaxant activities.
Journal: Journal of medicinal chemistry 20040617
Title: A NMR and theoretical study of the aggregates between alkyllithium and chiral lithium amides: control of the topology through a single asymmetric center.
Journal: Journal of the American Chemical Society 20021225
Title: Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1.
Journal: Journal of medicinal chemistry 20021205
