Home Amines 79416-27-6
79416-27-6,MFCD00012868
Catalog No.:AA0036DX

79416-27-6 | 5-Aminolevulinic acid methyl ester, HCl

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25mg
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250mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0036DX
Chemical Name:
5-Aminolevulinic acid methyl ester, HCl
CAS Number:
79416-27-6
Molecular Formula:
C6H12ClNO3
Molecular Weight:
181.6174
MDL Number:
MFCD00012868
SMILES:
NCC(=O)CCC(=O)OC.Cl
Properties
Properties
 
Form:
Solid  
MP:
119-121°  
Stability:
Light Sensitive/Hygroscopic  
Storage:
Room Temperature;  

Computed Properties
 
Complexity:
133  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  

Literature

Title: Comparison of the uptake of 5-aminolevulinic acid and its methyl ester in keratinocytes and skin.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20121001

Title: [Fluorescence diagnosis of non-melanoma skin cancer].

Journal: Orvosi hetilap 20120826

Title: δ-Aminolevulinic acid and its methyl ester induce the formation of Protoporphyrin IX in cultured sensory neurones.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20111201

Title: [Distal onycholysis resolved with photodynamic therapy in an elderly patient on multiple medication].

Journal: Enfermedades infecciosas y microbiologia clinica 20111001

Title: Optimization of photodynamic therapy response by survivin gene knockdown in human metastatic breast cancer T47D cells.

Journal: Journal of photochemistry and photobiology. B, Biology 20110902

Title: Increased cutaneous oxygen availability by topical application of hydrogen peroxide cream enhances the photodynamic reaction to topical 5-aminolevulinic acid-methyl ester.

Journal: Archives of dermatological research 20110501

Title: Treatment with 5-aminolaevulinic acid methylester is less painful than treatment with 5-aminolaevulinic acid nanoemulsion in topical photodynamic therapy for actinic keratosis.

Journal: Dermatology (Basel, Switzerland) 20110101

Title: Protoporphyrin IX photobleaching during the light irradiation phase of standard dermatological methyl-aminolevulinate photodynamic therapy.

Journal: Photodiagnosis and photodynamic therapy 20101201

Title: Microneedle pre-treatment of human skin improves 5-aminolevulininc acid (ALA)- and 5-aminolevulinic acid methyl ester (MAL)-induced PpIX production for topical photodynamic therapy without increase in pain or erythema.

Journal: Pharmaceutical research 20101001

Title: Efficacy of a methyl ester of 5-aminolevulinic acid in photodynamic therapy for ovarian cancers.

Journal: Journal of cancer research and clinical oncology 20100801

Title: [Erosive pustulosis on the scalp following dynamic phototherapy].

Journal: Annales de dermatologie et de venereologie 20100101

Title: Topical aminolaevulinic acid- and aminolaevulinic acid methyl ester-based photodynamic therapy with red and violet light: influence of wavelength on pain and erythema.

Journal: The British journal of dermatology 20091101

Title: New aspects in photodynamic therapy of actinic keratoses.

Journal: Journal of photochemistry and photobiology. B, Biology 20090904

Title: Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy.

Journal: Journal of photochemistry and photobiology. B, Biology 20090904

Title: Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy.

Journal: Dermatology (Basel, Switzerland) 20090101

Title: Images in clinical medicine. Fluorescence diagnosis of subclinical actinic keratoses.

Journal: The New England journal of medicine 20080508

Title: Identification of tetrapyrrole compounds excreted by Rhodobacter sphaeroides and sources of the methyl hydrogens of bacteriochlorophyll a biosynthesized by R. sphaeroides, based on 13C-NMR spectral analysis of coproporphyrin III tetramethyl ester.

Journal: Chemical & pharmaceutical bulletin 20070701

Title: Topical photodynamic therapy of actinic keratosis in renal transplant recipients.

Journal: Transplantation proceedings 20070101

Title: Photodynamic therapy using a methyl ester of 5-aminolevulinic acid in recurrent Paget's disease of the vulva: a pilot study.

Journal: Gynecologic oncology 20061101

Title: A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts.

Journal: International journal of oncology 20061001

Title: The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid.

Journal: Journal of photochemistry and photobiology. B, Biology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The temperature dependence of porphyrin production in Propionibacterium acnes after incubation with 5-aminolevulinic acid (ALA) and its methyl ester (m-ALA).

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060101

Title: Influence of light exposure on the kinetics of protoporphyrin IX formation in normal skin of hairless mice after application of 5-aminolevulinic acid methyl ester.

Journal: The Journal of investigative dermatology 20051101

Title: Kinetics of protoporphyrin IX formation in rat oral mucosa and skin after application of 5-aminolevulinic acid and its methylester.

Journal: Photochemistry and photobiology 20050101

Title: Transdermal delivery from a lipid sponge phase--iontophoretic and passive transport in vitro of 5-aminolevulinic acid and its methyl ester.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20041124

Title: Iontophoretic delivery of 5-aminolevulinic acid and its methyl ester using a carbopol gel as vehicle.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20040723

Title: Allergic contact dermatitis to 5-aminolaevulinic acid methylester but not to 5-aminolaevulinic acid after photodynamic therapy.

Journal: The British journal of dermatology 20040101

Title: A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer.

Journal: International journal of oncology 20030201

Title: Comparative in vitro percutaneous penetration of 5-aminolevulinic acid and two of its esters through excised hairless mouse skin.

Journal: Lasers in surgery and medicine 20030101

Title: The role of light in the treatment of non-melanoma skin cancer using methyl aminolevulinate.

Journal: The Journal of dermatological treatment 20030101

Title: Clinical efficacy of methyl aminolevulinate (Metvix) photodynamic therapy.

Journal: The Journal of dermatological treatment 20030101

Title: Methyl aminolevulinate (Metvix) photodynamic therapy - practical pearls.

Journal: The Journal of dermatological treatment 20030101

Title: Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice.

Journal: Biochemical and biophysical research communications 20020927

Title: Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice.

Journal: Archives of dermatological research 20020701

Title: Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevulinic acid methyl ester.

Journal: Journal of photochemistry and photobiology. B, Biology 20020501

Title: Protoporphyrin IX distribution following local application of 5-aminolevulinic acid and its esterified derivatives in the tissue layers of the normal rat colon.

Journal: British journal of cancer 20011101

Title: 5-Aminolaevulinic acid methyl ester transport on amino acid carriers in a human colon adenocarcinoma cell line.

Journal: Photochemistry and photobiology 20010201

Title: Methyl aminolevulinate, From Wikipedia

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Tags:79416-27-6 Molecular Formula|79416-27-6 MDL|79416-27-6 SMILES|79416-27-6 5-Aminolevulinic acid methyl ester, HCl