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79756-69-7,MFCD00448731
Catalog No.:AA01EAYZ

79756-69-7 | TPI-1

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$53.00   $37.00
- +
5mg
≥95%
in stock  
$230.00   $161.00
- +
10mg
≥95%
in stock  
$405.00   $283.00
- +
25mg
99%
in stock  
$696.00   $487.00
- +
100mg
97%
in stock  
$2,072.00   $1,450.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EAYZ
Chemical Name:
TPI-1
CAS Number:
79756-69-7
Molecular Formula:
C12H6Cl2O2
Molecular Weight:
253.0808
MDL Number:
MFCD00448731
SMILES:
Clc1ccc(cc1C1=CC(=O)C=CC1=O)Cl
NSC Number:
731240
Properties
Computed Properties
 
Complexity:
385  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
2.9  

Upstream Synthesis Route

[1]EuropeanJournalofMedicinalChemistry,2010,vol.45,#12,p.5833-5847

[2]ChemicalResearchinToxicology,1996,vol.9,#3,p.623-629

[1]JournaloftheChemicalSociety,ChemicalCommunications,1981,#16,p.859-860

[2]JournalofOrganicChemistry,1985,vol.50,#26,p.5546-5550

Literature

Title: Kundu S, et al. Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents. J Immunol. 2010 Jun 1;184(11):6529-36.

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SDS
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