Home Other Building Blocks 79952-42-4
79952-42-4,MFCD09832923
Catalog No.:AA0054CK

79952-42-4 | Monacolin J

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$116.00   $81.00
- +
5mg
95%
in stock  
$343.00   $240.00
- +
10mg
95%
in stock  
$588.00   $412.00
- +
25mg
95%
in stock  
$790.00   $553.00
- +
50mg
95%
in stock  
$1,111.00   $778.00
- +
100mg
95%
in stock  
$1,593.00   $1,115.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0054CK
Chemical Name:
Monacolin J
CAS Number:
79952-42-4
Molecular Formula:
C19H26O2
Molecular Weight:
286.4085
MDL Number:
MFCD09832923
SMILES:
O=C1C[CH]C[C@H](O1)CC[C@H]1[C@@H](C)C=CC2=C[C@@H](C[CH][C@H]12)C
Properties
Properties
 
Form:
Solid  
MP:
104-114°C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
510  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
2.3  

Literature

Title: Cytotoxic dehydromonacolins from red yeast rice.

Journal: Journal of agricultural and food chemistry 20120201

Title: Double oxidation of the cyclic nonaketide dihydromonacolin L to monacolin J by a single cytochrome P450 monooxygenase, LovA.

Journal: Journal of the American Chemical Society 20110601

Title: Semisynthesis of novel monacolin J derivatives: hypocholesterolemic and neuroprotective activities.

Journal: The Journal of antibiotics 20100801

Title: Identification of mokB involved in monacolin K biosynthesis in Monascus pilosus.

Journal: Biotechnology letters 20091201

Title: Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity.

Journal: Biotechnology and bioengineering 20090101

Title: [Biosynthesis of simvastatin--a mini-review].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080301

Title: Endo A, et al. Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus ruber. J Antibiot (Tokyo). 1985 Mar;38(3):420-2.

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SDS
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