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80-70-6,MFCD00075588
Catalog No.:AA003D3R

80-70-6 | 1,1,3,3-Tetramethylguanidine

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5g
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$5.00   $3.00
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25g
97%
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$16.00   $11.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003D3R
Chemical Name:
1,1,3,3-Tetramethylguanidine
CAS Number:
80-70-6
Molecular Formula:
C5H13N3
Molecular Weight:
115.1768
MDL Number:
MFCD00075588
SMILES:
CN(C(=N)N(C)C)C
NSC Number:
148309
Properties
Properties
 
Form:
Liquid  
Storage:
Light sensitive;Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
75.7  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
0.4  

Upstream Synthesis Route

[1]JournalofOrganicChemistry,2007,vol.72,#11,p.4067-4072

[1]JournaloftheAmericanChemicalSociety,1976,vol.98,p.1870-1875

[1]Patent:US6683198,2004,B1,.Locationinpatent:Pagecolumn3-4

[1]Hoppe-Seyler'sZeitschriftfuerPhysiologischeChemie,1924,vol.141,p.141

[1]JournalofOrganicChemistry,2007,vol.72,#11,p.4067-4072

Downstream Synthesis Route
5580-79-0    80-70-6   
<i>N</i>,<i>N</i>,<i>N</i>',<i>N</i>'-tetramethyl-<i>N</i>''-(2,3,4-trifluoro-6-nitro-phenyl)-guanidine 
 
<i>N</i>,<i>N</i>,<i>N</i>',<i>N</i>'-tetramethyl-<i>N</i>''-(2,3,6-trifluoro-4-nitro-phenyl)-guanidine 

[1]JournalofMolecularStructure,1999,vol.478,p.243-253

1493-27-2    80-70-6    610-17-3   
1,1,3,3-tetramethyl-2-(2-nitrophenyl)guanidine 

[1]JournalofChemicalResearch-PartS,2002,p.69-71

[1]JournalofChemicalResearch-PartS,2002,p.69-71

118-83-2    80-70-6   
dimethyl-(4-nitro-3-trifluoromethyl-phenyl)-amine 

[1]JournalofChemicalResearch-PartS,2002,p.69-71

[1]JournalofChemicalResearch-PartS,2002,p.69-71

Literature

Title: Pt(II)-mediated imine-nitrile coupling leading to symmetrical (1,3,5,7,9-pentaazanona-1,3,6,8-tetraenato)Pt(II) complexes containing the incorporated 1,3-diiminoisoindoline moiety.

Journal: Inorganic chemistry 20121015

Title: Sensitive analyses of neutral N-glycans using anion-doped liquid matrix G3CA by negative-ion matrix-assisted laser desorption/ionization mass spectrometry.

Journal: Analytical chemistry 20120717

Title: Accurate and reliable quantification of total microalgal fuel potential as fatty acid methyl esters by in situ transesterification.

Journal: Analytical and bioanalytical chemistry 20120401

Title: Transcriptional gene silencing of kallikrein 5 and kallikrein 7 using siRNA prevents epithelial cell detachment induced by alkaline shock in an in vitro model of eczema.

Journal: Biotechnology progress 20120101

Title: Ionic liquid catalysed synthesis of β-hydroxy ketones.

Journal: ChemSusChem 20110822

Title: Mechanistic considerations of guanidine-catalyzed reactions.

Journal: Chemical communications (Cambridge, England) 20110807

Title: Distillable acid-base conjugate ionic liquids for cellulose dissolution and processing.

Journal: Angewandte Chemie (International ed. in English) 20110704

Title: 2-Diazo-1-(1,1-dioxothio-morpholin-4-yl)ethanone.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: Synthesis of 5-chloro-8-hydroxy-6-methoxy-3-pentylisocoumarin.

Journal: Journal of Asian natural products research 20110601

Title: 2-[2-(Benzyl-sulfan-yl)phen-yl]-1,1,3,3-tetra-methyl-guanidine.

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: SO2 capture by guanidinium-based ionic liquids: a theoretical study.

Journal: The journal of physical chemistry. B 20110407

Title: Organocatalytic sequential Michael reactions: stereoselective synthesis of multifunctionalized tetrahydroindan derivatives.

Journal: Organic letters 20110304

Title: Systematic investigation on the synthesis of androstane-based 3-, 11- and 17-carboxamides via palladium-catalyzed aminocarbonylation.

Journal: Steroids 20110201

Title: Intramolecular bromonium ion assisted epoxide ring-opening: capture of the oxonium ion with an added external nucleophile.

Journal: The Journal of organic chemistry 20110107

Title: Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control.

Journal: International journal of molecular sciences 20110101

Title: X-ray crystal structure, Raman spectroscopy, and Ab initio density functional theory calculations on 1,1,3,3-tetramethylguanidinium bromide.

Journal: The journal of physical chemistry. A 20101223

Title: The nature of protic ionic liquids in the gas phase revisited: Fourier transform ion cyclotron resonance mass spectrometry study of 1,1,3,3-tetramethylguanidinium chloride.

Journal: The journal of physical chemistry. B 20100715

Title: tert-Butyl 4-(2-diazo-acet-yl)piperazine-1-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20100601

Title: HABA-based ionic liquid matrices for UV-MALDI-MS analysis of heparin and heparan sulfate oligosaccharides.

Journal: Glycobiology 20100201

Title: 1,1,3,3-Tetramethylguanidine solvated lanthanide aryloxides: pre-catalysts for intramolecular hydroalkoxylation.

Journal: Dalton transactions (Cambridge, England : 2003) 20091221

Title: One-step synthesis and bioassay of N-phosphoramidophosphonates.

Journal: Chemical & pharmaceutical bulletin 20091201

Title: Use of a novel ionic liquid matrix for MALDI-MS analysis of glycopeptides and glycans out of total tryptic digests.

Journal: Journal of mass spectrometry : JMS 20091101

Title: Structurally characterized 1,1,3,3-tetramethylguanidine solvated magnesium aryloxide complexes: [Mg(mu-OEt)(DBP)(H-TMG)]2, [Mg(mu-OBc)(DBP)(H-TMG)]2, [Mg(mu-TMBA)(DBP)(H-TMG)]2, [Mg(mu-DPP)(DBP)(H-TMG)]2, [Mg(BMP)2(H-TMG)2], [Mg(O-2,6-Ph2C6H3)2 (H-TMG)2].

Journal: Inorganic chemistry 20090406

Title: The synthesis of 13alpha-androsta-5,16-diene derivatives with carboxylic acid, ester and carboxamido functionalities at position-17 via palladium-catalyzed carbonylation.

Journal: Steroids 20090101

Title: Synthetic applications of polystyrene-supported 1,1,3,3-tetramethylguanidine.

Journal: Combinatorial chemistry & high throughput screening 20081201

Title: Formation of an ion-pair molecule with a single NH(+)...Cl(-) hydrogen bond: Raman spectra of 1,1,3,3-tetramethylguanidinium chloride in the solid state, in solution, and in the vapor phase.

Journal: The journal of physical chemistry. A 20080918

Title: The synthesis of 17-alkoxycarbonyl- and 17-carboxamido-13alpha-estra-1,3,5(10),16-tetraene derivatives via palladium-catalyzed carbonylation reactions.

Journal: Steroids 20080701

Title: Stable analogs of the uranyl ion containing 1,1,3,3-tetramethylguanidine.

Journal: Dalton transactions (Cambridge, England : 2003) 20071107

Title: Facile synthesis of 11-carboxamido-androst-4,9(11)-dienes via palladium-catalyzed aminocarbonylation.

Journal: Steroids 20070701

Title: Pt(II)-mediated nitrile-tetramethylguanidine coupling as a key step for a novel synthesis of 1,6-dihydro-1,3,5-dihydrotriazines.

Journal: Inorganic chemistry 20070305

Title: Structural and theoretical investigation of 2-iminoimidazolines--carbene analogues of iminophosphoranes.

Journal: Organic & biomolecular chemistry 20070207

Title: Similarities and differences between organic cation inhibition of the Na,K-ATPase and PMCA.

Journal: Biochemistry 20061107

Title: Facile synthesis of 12-carboxamido-11-spirostenes via palladium-catalyzed carbonylation reactions.

Journal: Steroids 20061001

Title: New force field for molecular simulation of guanidinium-based ionic liquids.

Journal: The journal of physical chemistry. B 20060622

Title: [Study on the vibrational spectra of two nitrobenzoyl substituted guanidines].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20060401

Title: Microwave-assisted synthesis of pt nanocrystals and deposition on carbon nanotubes in ionic liquids.

Journal: Journal of nanoscience and nanotechnology 20060101

Title: Guanidinophosphazenes: design, synthesis, and basicity in THF and in the gas phase.

Journal: Journal of the American Chemical Society 20051221

Title: Practical synthesis of the new carbapenem antibiotic ertapenem sodium.

Journal: The Journal of organic chemistry 20050916

Title: Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.

Journal: The Journal of investigative dermatology 20050901

Title: A new, efficient method for direct alpha-alkenylation of beta-dicarbonyl compounds and phenols using alkenyltriarylbismuthonium salts.

Journal: The Journal of organic chemistry 20040806

Title: Recommended methods of fatty acid methylester preparation for conjugated dienes and trienes in food and biological samples.

Journal: Journal of nutritional science and vitaminology 20040401

Title: pH directly regulates epidermal permeability barrier homeostasis, and stratum corneum integrity/cohesion.

Journal: The Journal of investigative dermatology 20030801

Title: A novel and convenient chemoselective deprotection method for both silyl and acetyl groups on acidic hydroxyl groups such as phenol and carboxylic acid by using a nitrogen organic base, 1,1,3,3-tetramethylguanidine.

Journal: Organic letters 20030123

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