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Home Bromides 809272-64-8
809272-64-8,MFCD19443182
Catalog No.:AA00G4ZH

809272-64-8 | Phosphonic acid, [(3-broMo-7-cyano-2-naphthalenyl)difluoroMethyl]- (9CI)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$458.00   $320.00
- +
5mg
95%
1 week  
$1,166.00   $816.00
- +
25mg
95%
1 week  
$1,726.00   $1,208.00
- +
50mg
95%
1 week  
$2,320.00   $1,624.00
- +
100mg
95%
1 week  
$2,915.00   $2,040.00
- +
  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00G4ZH
Chemical Name:
Phosphonic acid, [(3-broMo-7-cyano-2-naphthalenyl)difluoroMethyl]- (9CI)
CAS Number:
809272-64-8
Molecular Formula:
C12H7BrF2NO3P
Molecular Weight:
362.0634
MDL Number:
MFCD19443182
SMILES:
N#Cc1ccc2c(c1)cc(c(c2)Br)C(P(=O)(O)O)(F)F
Properties
Computed Properties
 
Complexity:
475  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
2.3  

Literature

Title: Using small molecules to target protein phosphatases.

Journal: Bioorganic & medicinal chemistry 20110401

Title: Recent advances in the discovery of competitive protein tyrosine phosphatase 1B inhibitors for the treatment of diabetes, obesity, and cancer.

Journal: Journal of medicinal chemistry 20100325

Title: Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20080601

Title: Yongxin Han, et al. Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methylphosphonic acid, a potent and orally active small molecule PTP1B inhibitor. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3200-5.

Title: Patel D, .Discovery of orally active, potent, and selective benzotriazole-based PTP1B inhibitors. ChemMedChem. 2011 Jun 6; 6(6):1011-6.

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Tags:809272-64-8 Molecular Formula|809272-64-8 MDL|809272-64-8 SMILES|809272-64-8 Phosphonic acid, [(3-broMo-7-cyano-2-naphthalenyl)difluoroMethyl]- (9CI)