Home Other Building Blocks 817194-38-0
817194-38-0,MFCD30533616
Catalog No.:AA01EO3Z

817194-38-0 | GSK180736A

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$8.00   $6.00
- +
2mg
97%
in stock  
$12.00   $8.00
- +
5mg
97%
in stock  
$19.00   $14.00
- +
10mg
97%
in stock  
$28.00   $20.00
- +
50mg
97%
in stock  
$78.00   $55.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO3Z
Chemical Name:
GSK180736A
CAS Number:
817194-38-0
Molecular Formula:
C19H16FN5O2
Molecular Weight:
365.3610
MDL Number:
MFCD30533616
SMILES:
O=C1NC(=C(C(N1)c1ccc(cc1)F)C(=O)Nc1ccc2c(c1)cn[nH]2)C
Properties
Computed Properties
 
Complexity:
632  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.7  

Literature

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters 20130801

Title: Potent, selective and orally bioavailable dihydropyrimidine inhibitors of Rho kinase (ROCK1) as potential therapeutic agents for cardiovascular diseases.

Journal: Journal of medicinal chemistry 20081113

Title: Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors.

Journal: Journal of medicinal chemistry 20070111

Title: Waldschmidt HV, et al. Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors. J Med Chem. 2016 Apr 28;59(8):3793-807.

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SDS
Tags:817194-38-0 Molecular Formula|817194-38-0 MDL|817194-38-0 SMILES|817194-38-0 GSK180736A