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Title: Use of 2'-spirocyclic ethers in HCV nucleoside design.
Journal: Journal of medicinal chemistry 20140313
Title: Nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as novel inhibitors of the HCV NS5B polymerase.
Journal: Journal of medicinal chemistry 20140313
Title: Antiviral activity of nucleoside analogues against norovirus.
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Title: 2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase.
Journal: Journal of medicinal chemistry 20101125
Title: PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
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Title: Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.
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Title: New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals.
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Title: An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase.
Journal: The Journal of organic chemistry 20090904
Title: The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors.
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Title: Combinations of 2'-C-methylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system.
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Title: Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.
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