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819-79-4,MFCD00034860
Catalog No.:AA003PHC

819-79-4 | Diisopropylamine HCl

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003PHC
Chemical Name:
Diisopropylamine HCl
CAS Number:
819-79-4
Molecular Formula:
C6H16ClN
Molecular Weight:
137.6509
MDL Number:
MFCD00034860
SMILES:
CC(NC(C)C)C.Cl
NSC Number:
1808
Properties
Properties
 
Form:
Solid  
MP:
216-218 °C(lit.)  
Storage:
Room Temperature;Inert atmosphere;  

Computed Properties
 
Complexity:
33.4  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  

Downstream Synthesis Route
36975-15-2    50-00-0    819-79-4   
3-diisopropylamino-1-4-methyl-2-(3-nitro-benzoylamino)-thiazol-5-yl-propan-1-one 

[1]Suciu,D.[JournalfurpraktischeChemie(Leipzig1954),1971,vol.313,p.193-204]

50-00-0    32519-70-3    819-79-4   
1-2-(2-chloro-acetylamino)-4-methyl-thiazol-5-yl-3-diisopropylamino-propan-1-one 

[1]Suciu,D.[JournalfurpraktischeChemie(Leipzig1954),1971,vol.313,p.193-204]

50-00-0   
(2-Chloro-cyclopentyl)-phosphinicacidethylester 
  819-79-4   
Cyclopent-1-enyl-(diisopropylamino)-methyl-phosphinicacidethylester 

[1]Grapov,A.F.etal.[JournalofgeneralchemistryoftheUSSR,1977,vol.47,p.1347-1349][ZhurnalObshcheiKhimii,1977,vol.47,p.1465-1468]

50-00-0   
(2-Chloro-cyclohexyl)-phosphinicacidethylester 
  819-79-4   
(2-Chloro-cyclohexyl)-(diisopropylamino)-methyl-phosphinicacidethylester 

[1]Grapov,A.F.etal.[JournalofgeneralchemistryoftheUSSR,1977,vol.47,p.1347-1349][ZhurnalObshcheiKhimii,1977,vol.47,p.1465-1468]

50-00-0    39884-12-3    819-79-4   
1-(2-acetylamino-4-methyl-thiazol-5-yl)-3-diisopropylamino-propan-1-one 

[1]Suciu,D.[JournalfurpraktischeChemie(Leipzig1954),1971,vol.313,p.193-204]

Literature

Title: Mechanisms of drug resistance reversal in Dox-resistant MCF-7 cells by pH-responsive amphiphilic polyphosphazene containing diisopropylamino side groups.

Journal: Molecular pharmaceutics 20120507

Title: Diisopropylammonium chloride: a ferroelectric organic salt with a high phase transition temperature and practical utilization level of spontaneous polarization.

Journal: Advanced materials (Deerfield Beach, Fla.) 20111215

Title: Computational studies of lithium diisopropylamide deaggregation.

Journal: The Journal of organic chemistry 20111007

Title: Regioselective lithium diisopropylamide-mediated ortholithiation of 1-chloro-3-(trifluoromethyl)benzene: role of autocatalysis, lithium chloride catalysis, and reversibility.

Journal: Journal of the American Chemical Society 20110511

Title: Design, synthesis, and sustained-release property of 1,3-cyclic propanyl phosphate ester of 18β-glycyrrhetinic acid.

Journal: Chemical biology & drug design 20110301

Title: 1,4-addition of lithium diisopropylamide to unsaturated esters: role of rate-limiting deaggregation, autocatalysis, lithium chloride catalysis, and other mixed aggregation effects.

Journal: Journal of the American Chemical Society 20101110

Title: α-Lithiation and electrophilic substitution of 1,4,4-trimethyl-3,4-dihydroquinolin-2-one.

Journal: Molecules (Basel, Switzerland) 20101029

Title: Mechanism of lithium diisopropylamide-mediated substitution of 2,6-difluoropyridine.

Journal: Journal of the American Chemical Society 20100512

Title: Diisopropylamide and TMP turbo-Grignard reagents: a structural rationale for their contrasting reactivities.

Journal: Angewandte Chemie (International ed. in English) 20100419

Title: Interactions of diorganolead(IV) with 3-(2-thienyl)-2-sulfanylpropenoic acid and/or thiamine: chemical and in vitro and in vivo toxicological results.

Journal: Inorganic chemistry 20100301

Title: Characterizing the Memory Effect on the amylose tris(3,5-dimethylphenyl) carbamate stationary phase.

Journal: Journal of chromatography. A 20091127

Title: Lithium diisopropylamide-mediated ortholithiations: lithium chloride catalysis.

Journal: The Journal of organic chemistry 20090306

Title: Autocatalysis in lithium diisopropylamide-mediated ortholithiations.

Journal: Journal of the American Chemical Society 20081231

Title: Decoupling deprotonation from metalation: Thia-Fries rearrangement.

Journal: Angewandte Chemie (International ed. in English) 20080101

Title: Lithium diisopropylamide: solution kinetics and implications for organic synthesis.

Journal: Angewandte Chemie (International ed. in English) 20070101

Title: Lithium diisopropylamide solvated by hexamethylphosphoramide: substrate-dependent mechanisms for dehydrobrominations.

Journal: Journal of the American Chemical Society 20061206

Title: Lithium diisopropylamide-mediated ortholithiation and anionic fries rearrangement of aryl carbamates: role of aggregates and mixed aggregates.

Journal: Journal of the American Chemical Society 20061025

Title: Lithium diisopropylamide-mediated enolization: catalysis by hemilabile ligands.

Journal: Journal of the American Chemical Society 20060809

Title: Enantioselective modular synthesis of 2,4-disubstituted cyclopentenones by iridium-catalyzed allylic alkylation.

Journal: Angewandte Chemie (International ed. in English) 20060403

Title: Metal enolates of alpha-CF3 ketones: theoretical guideline, direct generation, and synthetic use.

Journal: Chemical record (New York, N.Y.) 20060101

Title: Synthesis of a four-coordinate titanium(IV) oxoanion via deprotonation and decarbonylation of complexed formate.

Journal: Chemical communications (Cambridge, England) 20050721

Title: A new mechanism for nucleophilic substitution at a thiophosphoryl centre revealed by the reaction of diisopropylamine with PSCl3.

Journal: Chemical communications (Cambridge, England) 20050614

Title: Application of colorimetric indicators and thermo-hand method to determine base permeation through chemical protective gloves.

Journal: Journal of occupational and environmental hygiene 20041201

Title: Use of a directional spray system design to control respirable dust and face gas concentrations around a continuous mining machine.

Journal: Journal of occupational and environmental hygiene 20041201

Title: Lithium diisopropylamide-mediated lithiations of imines: insights into highly structure-dependent rates and selectivities.

Journal: Journal of the American Chemical Society 20031210

Title: Ketone enolization with lithium dialkylamides: the effects of structure, solvation, and mixed aggregates with excess butyllithium.

Journal: The Journal of organic chemistry 20030808

Title: BuMgNiPr2: a new base for stoichiometric, position-selective deprotonation of cyclopropane carboxamides and other weak CH acids.

Journal: Angewandte Chemie (International ed. in English) 20020617

Title: New entry of coupling reaction of phenacylamine derivatives with silylstannane.

Journal: Chemical & pharmaceutical bulletin 20020301

Title: Lithium diisopropylamide: oligomer structures at low ligand concentrations.

Journal: Journal of the American Chemical Society 20010117

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