Home Other Building Blocks 82189-04-6
82189-04-6,MFCD01674355
Catalog No.:AA00G9KK

82189-04-6 | mycotrienin II

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$505.00   $353.00
- +
5mg
≥95%
in stock  
$1,950.00   $1,365.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G9KK
Chemical Name:
mycotrienin II
CAS Number:
82189-04-6
Molecular Formula:
C36H50N2O8
Molecular Weight:
638.7908
MDL Number:
MFCD01674355
SMILES:
CO[C@H]1/C=C/C=C/C=C/C[C@H](OC(=O)[C@H](NC(=O)C2CCCCC2)C)[C@H](C)[C@H](/C(=C\CCc2c(c(NC(=O)C1)cc(O)c2)O)/C)O
Properties
Computed Properties
 
Complexity:
1110  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
46  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
4  
XLogP3:
5.5  

Literature

Title: Mycotrienin II, a translation inhibitor that prevents ICAM-1 expression induced by pro-inflammatory cytokines.

Journal: The Journal of antibiotics 20110501

Title: Trierixin, a novel Inhibitor of ER stress-induced XBP1 activation from Streptomyces sp. 1. Taxonomy, fermentation, isolation and biological activities.

Journal: The Journal of antibiotics 20070901

Title: Trierixin, a novel Inhibitor of ER stress-induced XBP1 activation from Streptomyces sp. II. structure elucidation.

Journal: The Journal of antibiotics 20070901

Title: M Sugita, et al. Studies on Mycotrienin Antibiotics, a Novel Class of Ansamycins. I. Taxonomy, Fermentation, Isolation and Properties of Mycotrienins I and II. J Antibiot (Tokyo). 1982 Nov;35(11):1460-6.

Title: D Feuerbach, et al. Mycotrienins. A New Class of Potent Inhibitors of Osteoclastic Bone Resorption. J Biol Chem. 1995 Oct 27;270(43):25949-55.

Title: Yuriko Yamada, et al.Mycotrienin II, a Translation Inhibitor That Prevents ICAM-1 Expression Induced by Pro-Inflammatory Cytokines. J Antibiot (Tokyo). 2011 May;64(5):361-6.

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