[1]Heterocycles,1998,vol.48,#8,p.1527-1535
[1]TetrahedronLetters,2001,vol.42,#3,p.477-479
[1]Heterocycles,1998,vol.48,#8,p.1527-1535
[1]Heterocycles,1998,vol.48,#8,p.1527-1535
[1]Heterocycles,1998,vol.48,#8,p.1527-1535
Title: The trifunctional protein mediates thyroid hormone receptor-dependent stimulation of mitochondria metabolism.
Journal: Molecular endocrinology (Baltimore, Md.) 20120701
Title: Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.
Journal: Gastroenterology 20120401
Title: Integrin-dependent Akt1 activation regulates PGC-1 expression and fatty acid oxidation.
Journal: Journal of vascular research 20120401
Title: Inhibition of fatty acid metabolism reduces human myeloma cells proliferation.
Journal: PloS one 20120101
Title: Metabolic modulation: a new therapeutic target in treatment of heart failure.
Journal: American journal of therapeutics 20111101
Title: Altered HepG2 cell models using etomoxir versus tert-butylhydroperoxide.
Journal: Cell biology and toxicology 20111001
Title: Uterine contractility is strongly influenced by steroids and glucose metabolism: an in vitro study on bovine myometrium.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110901
Title: Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells.
Journal: Biochimica et biophysica acta 20110601
Title: Carnitine palmitoyltransferase (CPT) modulators: a medicinal chemistry perspective on 35 years of research.
Journal: Journal of medicinal chemistry 20110512
Title: Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase.
Journal: The Biochemical journal 20110501
Title: Stimulation of lipogenesis as well as fatty acid oxidation protects against palmitate-induced INS-1 beta-cell death.
Journal: Endocrinology 20110301
Title: Fatty acid (FFA) transport in cardiomyocytes revealed by imaging unbound FFA is mediated by an FFA pump modulated by the CD36 protein.
Journal: The Journal of biological chemistry 20110211
Title: Radiochemical synthesis of etomoxir.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20110201
Title: Lipotoxicity is glucose-dependent in INS-1E cells but not in human islets and MIN6 cells.
Journal: Lipids in health and disease 20110101
Title: Inhibition of fatty acid metabolism ameliorates disease activity in an animal model of multiple sclerosis.
Journal: Scientific reports 20110101
Title: Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100801
Title: Synthesis and preliminary evaluation of 18-(18)F-fluoro-4-thia-oleate as a PET probe of fatty acid oxidation.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100801
Title: Acute inhibition of fatty acid import inhibits GLUT4 transcription in adipose tissue, but not skeletal or cardiac muscle tissue, partly through liver X receptor (LXR) signaling.
Journal: Diabetes 20100401
Title: Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells.
Journal: Endocrinology 20100401
Title: Validation of (99m)Tc-labeled '4+1' fatty acids for myocardial metabolism and flow imaging: Part 2. Subcellular distribution.
Journal: Nuclear medicine and biology 20091001
Title: The metabolic modulators, Etomoxir and NVP-LAB121, fail to reverse pressure overload induced heart failure in vivo.
Journal: Basic research in cardiology 20090901
Title: Fatty acid oxidation and meiotic resumption in mouse oocytes.
Journal: Molecular reproduction and development 20090901
Title: Thyroid hormones act indirectly to increase sex hormone-binding globulin production by liver via hepatocyte nuclear factor-4alpha.
Journal: Journal of molecular endocrinology 20090701
Title: Acute effects of pharmacological modifications of fatty acid metabolism on human satiety.
Journal: The British journal of nutrition 20090601
Title: Etomoxir-induced partial carnitine palmitoyltransferase-I (CPT-I) inhibition in vivo does not alter cardiac long-chain fatty acid uptake and oxidation rates.
Journal: The Biochemical journal 20090415
Title: Influence of mitochondrial β-oxidation on early pea seedling development.
Journal: The New phytologist 20090301
Title: Characterization of hepatic mitochondrial injury induced by fatty acid oxidation inhibitors.
Journal: Toxicologic pathology 20090101
Title: The metabolic treatment of coronary artery disease and heart failure.
Journal: Current pharmaceutical design 20090101
Title: Arachidonic acid-induced apoptosis in rat hepatoma AS-30D cells is mediated by reactive oxygen species.
Journal: Acta biochimica Polonica 20090101
Title: AMPK-independent pathways regulate skeletal muscle fatty acid oxidation.
Journal: The Journal of physiology 20081201
Title: Saturated fatty acids inhibit hepatic insulin action by modulating insulin receptor expression and post-receptor signalling.
Journal: Journal of biochemistry 20081101
Title: Hypoxic induction of UCP3 in the growth plate: UCP3 suppresses chondrocyte autophagy.
Journal: Journal of cellular physiology 20080801
Title: AMPK activator, AICAR, inhibits palmitate-induced apoptosis in osteoblast.
Journal: Bone 20080801
Title: Antiarrhythmic and arrhythmogenic effects of L-carnitine in ischemia and reperfusion.
Journal: Bulletin of experimental biology and medicine 20080801
Title: Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2-deoxyglucose and etomoxir.
Journal: International journal of cancer 20080715
Title: Metabolic agents in the management of diabetic coronary patients: a new era.
Journal: International journal of cardiology 20080623
Title: Metabolic agents in the management of diabetic coronary patients: a new era.
Journal: International journal of cardiology 20080623
Title: Evidence for AMPK-dependent regulation of exocytosis of lipoproteins in a model liver cell line.
Journal: Experimental cell research 20080610
Title: Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080201
Title: Peroxisome proliferator-activated receptor alpha-retinoid X receptor agonists induce beta-cell protection against palmitate toxicity.
Journal: The FEBS journal 20071201
Title: Low utilization of circulating glucose after food withdrawal in Snell dwarf mice.
Journal: The Journal of biological chemistry 20071130
Title: Peroxisomal-mitochondrial oxidation in a rodent model of obesity-associated insulin resistance.
Journal: American journal of physiology. Endocrinology and metabolism 20071001
Title: A double-blind randomized multicentre clinical trial to evaluate the efficacy and safety of two doses of etomoxir in comparison with placebo in patients with moderate congestive heart failure: the ERGO (etomoxir for the recovery of glucose oxidation) study.
Journal: Clinical science (London, England : 1979) 20070801
Title: Suppression of virus replication via down-modulation of mitochondrial short chain enoyl-CoA hydratase in human glioblastoma cells.
Journal: Antiviral research 20070801
Title: Fatty acid-induced effect on glucagon secretion is mediated via fatty acid oxidation.
Journal: Diabetes/metabolism research and reviews 20070301
Title: Consequences of mitochondrial injury induced by pharmaceutical fatty acid oxidation inhibitors is characterized in human and rat liver slices.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20061001
Title: 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside-induced AMP-activated protein kinase phosphorylation inhibits basal and insulin-stimulated glucose uptake, lipid synthesis, and fatty acid oxidation in isolated rat adipocytes.
Journal: The Journal of biological chemistry 20060908
Title: Modification of myocardial substrate use as a therapy for heart failure.
Journal: Nature clinical practice. Cardiovascular medicine 20060901
Title: Metabolic therapeutics in angina pectoris: history revisited with perhexiline.
Journal: European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology 20060601
Title: Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation.
Journal: Biochemistry 20060411
Title: Temperature dependence of O2 consumption; opposite effects of leptin and etomoxir on respiratory quotient in mice.
Journal: Obesity (Silver Spring, Md.) 20060401
Title: Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels.
Journal: Diabetes 20051201
Title: A new therapeutic approach to treat psoriasis by inhibition of fatty acid oxidation by Etomoxir.
Journal: The British journal of dermatology 20051101
Title: Myocardial protection from ischemic preconditioning is not blocked by sub-chronic inhibition of carnitine palmitoyltransferase I.
Journal: Life sciences 20050902
Title: A role for PPARalpha in the control of SREBP activity and lipid synthesis in the liver.
Journal: The Biochemical journal 20050715
Title: Fatty acid oxidation inhibition with PPARalpha activation (FOXIB/PPARalpha) for normalizing gene expression in heart failure?
Journal: Cardiovascular research 20050601
Title: [Metabolism and the hypertrophied heart of the elderly].
Journal: Deutsche medizinische Wochenschrift (1946) 20050324
Title: Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G.
Journal: Cardiovascular diabetology 20050101
Title: Cardiac metabolism as a target for the treatment of heart failure.
Journal: Circulation 20040824
Title: Metabolic manipulation in ischaemic heart disease, a novel approach to treatment.
Journal: European heart journal 20040401
Title: Etomoxir, a fatty acid oxidation inhibitor, increases food intake and reduces hepatic energy status in rats.
Journal: Physiology & behavior 20040301
Title: Drug development based on functional genomics of overloaded cardiomyocytes: a novel approach for preventing progression of heart failure.
Journal: Journal of muscle research and cell motility 20040101
Title: Uncoupling protein 3 as a mitochondrial fatty acid anion exporter.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031201
Title: Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.
Journal: Cancer research 20031101
Title: Protein acylation in the inhibition of insulin secretion by norepinephrine, somatostatin, galanin, and PGE2.
Journal: American journal of physiology. Endocrinology and metabolism 20030801
Title: Inhibition of carnitine palmitoyltransferase in the rat small intestine reduces export of triacylglycerol into the lymph.
Journal: Journal of lipid research 20030701
Title: Down-regulation of acyl-CoA oxidase gene expression and increased NF-kappaB activity in etomoxir-induced cardiac hypertrophy.
Journal: Journal of lipid research 20030201
Title: Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells.
Journal: Journal of lipid research 20030201
Title: Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation.
Journal: Journal of lipid research 20030101
Title: The use of partial fatty acid oxidation inhibitors for metabolic therapy of angina pectoris and heart failure.
Journal: Herz 20021101
Title: Etomoxir-induced increase in UCP3 supports a role of uncoupling protein 3 as a mitochondrial fatty acid anion exporter.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: Etomoxir-induced oxidative stress in HepG2 cells detected by differential gene expression is confirmed biochemically.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020701
Title: Inhibition of glycogen synthesis by fatty acid in C(2)C(12) muscle cells is independent of PKC-alpha, -epsilon, and -theta.
Journal: American journal of physiology. Endocrinology and metabolism 20020601
Title: PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells.
Journal: Journal of lipid research 20020601
Title: Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretion.
Journal: The Biochemical journal 20020515
Title: Induction of uncoupling protein 2 mRNA in beta-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply.
Journal: Endocrinology 20020401
Title: Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells.
Journal: The Journal of biological chemistry 20020322
Title: Therapeutic potential of CPT I inhibitors: cardiac gene transcription as a target.
Journal: Expert opinion on investigational drugs 20020301
Title: [Functional genomics of pressure-loaded cardiomyocytes: etomoxir in heart failure?].
Journal: Herz 20020301
Title: Differential effects of etomoxir treatment on cardiac Na+-K+ ATPase subunits in diabetic rats.
Journal: Molecular and cellular biochemistry 20020301
Title: Co-administration of etomoxir and RU-486 mitigates insulin resistance in hepatic and muscular tissues of STZ-induced diabetic rats.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20011001
Title: Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.
Journal: Diabetes 20010801
Title: Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
Journal: Biochemical and biophysical research communications 20010713
Title: Uncoupling protein-3 mRNA up-regulation in C2C12 myotubes after etomoxir treatment.
Journal: Biochimica et biophysica acta 20010629
Title: Post-transcriptional regulation of rat carnitine octanoyltransferase.
Journal: Biochemical Society transactions 20010501
Title: Involvement of 1,2-diacylglycerol in improvement of heart function by etomoxir in diabetic rats.
Journal: Life sciences 20010216
Title: Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats.
Journal: Diabetes 20010101
Title: Stereospecificity of the inhibition by etomoxir of fatty acid and cholesterol synthesis in isolated rat hepatocytes.
Journal: Biochemical pharmacology 19911009
Title: Interactions of inhibitors of carnitine palmitoyltransferase I and fibrates in cultured hepatocytes.
Journal: The Biochemical journal 19880701
