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82970-80-7,MFCD08460996
Catalog No.:AA00GALY

82970-80-7 | LYSO-SPHINGOMYELIN

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5mg
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10mg
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50mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GALY
Chemical Name:
LYSO-SPHINGOMYELIN
CAS Number:
82970-80-7
Molecular Formula:
C23H49N2O5P
Molecular Weight:
464.6193
MDL Number:
MFCD08460996
SMILES:
CCCCCCCCCCCCC/C=C/[C@H]([C@H](COP(=O)(OCC[N+](C)(C)C)[O-])N)O
Properties
Computed Properties
 
Complexity:
489  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
21  
XLogP3:
4.7  

Literature

Title: Characterization of Imidazopyridine Compounds as Negative Allosteric Modulators of Proton-Sensing GPR4 in Extracellular Acidification-Induced Responses.

Journal: PloS one 20150101

Title: International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands.

Journal: Pharmacological reviews 20130701

Title: PP2A and DUSP6 are involved in sphingosylphosphorylcholine-induced hypopigmentation.

Journal: Molecular and cellular biochemistry 20120801

Title: Regulated expression of pH sensing G Protein-coupled receptor-68 identified through chemical biology defines a new drug target for ischemic heart disease.

Journal: ACS chemical biology 20120615

Title: Simvastatin inhibits sphingosylphosphorylcholine-induced differentiation of human mesenchymal stem cells into smooth muscle cells.

Journal: Experimental & molecular medicine 20120227

Title: Sphingosylphosphorylcholine induces stress fiber formation via activation of Fyn-RhoA-ROCK signaling pathway in fibroblasts.

Journal: Cellular signalling 20120101

Title: Human vascular endothelial cells reduce sphingosylphosphorylcholine-induced smooth muscle cell contraction in co-culture system through integrin β4 and Fyn.

Journal: Acta pharmacologica Sinica 20120101

Title: The G protein coupled receptor 3 is involved in cAMP and cGMP signaling and maintenance of meiotic arrest in porcine oocytes.

Journal: PloS one 20120101

Title: Novel participation of transglutaminase-2 through c-Jun N-terminal kinase activation in sphingosylphosphorylcholine-induced keratin reorganization of PANC-1 cells.

Journal: Biochimica et biophysica acta 20111201

Title: Regulation of apoptosis and autophagy by sphingosylphosphorylcholine in vascular endothelial cells.

Journal: Journal of cellular physiology 20111101

Title: Sphingosylphosphorylcholine attenuated β-amyloid production by reducing BACE1 expression and catalysis in PC12 cells.

Journal: Neurochemical research 20111101

Title: Involvement of leukotriene B4 in spontaneous itch-related behaviour in NC mice with atopic dermatitis-like skin lesions.

Journal: Experimental dermatology 20111101

Title: Differentiation of adult stem cells into smooth muscle for vascular tissue engineering.

Journal: The Journal of surgical research 20110615

Title: Sphingosylphosphorylcholine stimulates CCL2 production from human umbilical vein endothelial cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20110401

Title: Sphingosylphosphorylcholine and lysosulfatide have inverse regulatory functions in monocytic cell differentiation into macrophages.

Journal: Archives of biochemistry and biophysics 20110201

Title: Sphingosylphosphorylcholine is a proinflammatory mediator in cerebral arteries.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110101

Title: Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects.

Journal: Journal of biomedical science 20110101

Title: Regulation of ryanodine receptors by sphingosylphosphorylcholine: involvement of both calmodulin-dependent and -independent mechanisms.

Journal: Biochemical and biophysical research communications 20101015

Title: Development of a sphingosylphosphorylcholine detection system using RNA aptamers.

Journal: Molecules (Basel, Switzerland) 20100820

Title: Sphingosylphosphorylcholine down-regulates filaggrin gene transcription through NOX5-based NADPH oxidase and cyclooxygenase-2 in human keratinocytes.

Journal: Biochemical pharmacology 20100701

Title: [Effect of ethanol on sphingosylphosphorylcholine (SPC)-induced vasoconstriction in rat artery].

Journal: Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence 20100601

Title: Sphingosylphosphorylcholine inhibits melanin synthesis via pertussis toxin-sensitive MITF degradation.

Journal: The Journal of pharmacy and pharmacology 20100201

Title: Dissociation of calmodulin-target peptide complexes by the lipid mediator sphingosylphosphorylcholine: implications in calcium signaling.

Journal: The Journal of biological chemistry 20100115

Title: Influence of phase separating lipids on supported lipid bilayer formation at SiO2 surfaces.

Journal: Physical chemistry chemical physics : PCCP 20100114

Title: Sphingosylphosphorylcholine induces degranulation of mast cells in the skin and plasma exudation in the ears of mice.

Journal: Journal of dermatological science 20100101

Title: Intravenous sphingosylphosphorylcholine protects ischemic and postischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury.

Journal: Mediators of inflammation 20100101

Title: Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin.

Journal: The Journal of investigative dermatology 20091201

Title: Lipids as targets for novel anti-inflammatory therapies.

Journal: Pharmacology & therapeutics 20091001

Title: Recognition of lyso-phospholipids by human natural killer T lymphocytes.

Journal: PLoS biology 20091001

Title: Elevated concentrations of sphingosylphosphorylcholine in cerebrospinal fluid after subarachnoid hemorrhage: a possible role as a spasmogen.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090801

Title: A possible mechanism underlying the ceramide deficiency in atopic dermatitis: expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide.

Journal: Journal of dermatological science 20090701

Title: Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery.

Journal: Cardiovascular research 20090501

Title: Nonkinase activity of MLCK in elongated filopodia formation and chemotaxis of vascular smooth muscle cells toward sphingosylphosphorylcholine.

Journal: American journal of physiology. Heart and circulatory physiology 20090501

Title: Effects of sphingosylphosphorylcholine against cholestatic oxidative stress and liver damage in the common bile duct ligated rats.

Journal: Journal of pediatric surgery 20090401

Title: Sphingomyelins in four ascidians, Ciona intestinalis, Halocynthia roretzi, Halocynthia aurantium, and Styela clava.

Journal: Journal of oleo science 20090101

Title: A Rho kinase/myocardin-related transcription factor-A-dependent mechanism underlies the sphingosylphosphorylcholine-induced differentiation of mesenchymal stem cells into contractile smooth muscle cells.

Journal: Circulation research 20080912

Title: Quantitative evaluation of sphingomyelin and glucosylceramide using matrix-assisted laser desorption ionization time-of-flight mass spectrometry with sphingosylphosphorylcholine as an internal standard. Practical application to tissues from patients with Niemann-Pick disease types A and C, and Gaucher disease.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080715

Title: Lysophospholipids and ATP mutually suppress maturation and release of IL-1 beta in mouse microglial cells using a Rho-dependent pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20080615

Title: Blebbistatin inhibits the chemotaxis of vascular smooth muscle cells by disrupting the myosin II-actin interaction.

Journal: American journal of physiology. Heart and circulatory physiology 20080501

Title: Characterizations of sphingosylphosphorylcholine-induced scratching responses in ICR mice using naltrexon, capsaicin, ketotifen and Y-27632.

Journal: European journal of pharmacology 20080331

Title: Sphingosylphosphorylcholine as a novel calmodulin inhibitor.

Journal: The Biochemical journal 20080301

Title: Low concentrations of sphingosylphosphorylcholine enhance pulmonary artery vasoreactivity: the role of protein kinase C delta and Ca2+ entry.

Journal: Hypertension (Dallas, Tex. : 1979) 20080201

Title: Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat.

Journal: Critical care medicine 20080201

Title: The multi-functional role of sphingosylphosphorylcholine.

Journal: Progress in lipid research 20080101

Title: Inhibitory effects of eicosapentaenoic acid on chronic cerebral vasospasm after subarachnoid hemorrhage: possible involvement of a sphingosylphosphorylcholine-rho-kinase pathway.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20080101

Title: Sphingosylphosphorylcholine induces mitochondria-mediated apoptosis in neuro 2a cells: involvement of protein kinase C.

Journal: Acta neurobiologiae experimentalis 20080101

Title: Novel neurotrophic effects of sphingosylphosphorylcholine in cerebellar granule neurons and in PC12 cells.

Journal: Biochemical and biophysical research communications 20071207

Title: The signaling mechanism of the sphingosylphosphorylcholine-induced contraction in cat esophageal smooth muscle cells.

Journal: Archives of pharmacal research 20071201

Title: Involvement of Fyn tyrosine kinase in actin stress fiber formation in fibroblasts.

Journal: FEBS letters 20071113

Title: Effect of direct albumin binding to sphingosylphosphorylcholine in Jurkat T cells.

Journal: Prostaglandins & other lipid mediators 20071101

Title: Agonist potency at P2X7 receptors is modulated by structurally diverse lipids.

Journal: British journal of pharmacology 20071001

Title: Effects of sphingosine-1-phosphate and sphingosylphosphorylcholine on intracellular Ca2+ and cell death in prostate cancer cell lines.

Journal: Autonomic & autacoid pharmacology 20071001

Title: Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1beta-induced prostaglandin E2 formation.

Journal: Journal of lipid research 20070901

Title: Antiproliferative effect of sphingosylphosphorylcholine in thyroid FRO cancer cells mediated by cell cycle arrest in the G2/M phase.

Journal: Molecular and cellular endocrinology 20070815

Title: Previously postulated 'ligand-independent' signaling of GPR4 is mediated through proton-sensing mechanisms.

Journal: Cellular signalling 20070801

Title: Sevoflurane, but not propofol, prevents Rho kinase-dependent contraction induced by sphingosylphosphorylcholine in the porcine coronary artery.

Journal: Anesthesia and analgesia 20070801

Title: Sphingosylphosphocholine effects on cultured astrocytes reveal mechanisms potentially involved in neurotoxicity in Niemann-Pick type A disease.

Journal: The European journal of neuroscience 20070801

Title: Sphingosylphosphorylcholine activates dendritic cells, stimulating the production of interleukin-12.

Journal: Immunology 20070701

Title: Vasorelaxing effect of the Rho-kinase inhibitor, Y-27632, in isolated canine basilar arteries.

Journal: Neurological research 20070701

Title: Sphingosylphosphorylcholine-induced interleukin-6 production is mediated by protein kinase C and p42/44 extracellular signal-regulated kinase in human dermal fibroblasts.

Journal: Journal of dermatological science 20070501

Title: Sphingosylphosphorylcholine induces apoptosis of endothelial cells through reactive oxygen species-mediated activation of ERK.

Journal: Journal of cellular biochemistry 20070415

Title: Vascular effects of sphingolipids.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20070401

Title: [Involvement of Fyn tyrosine kinase and membrane rafts in the signal transduction in Ca2+-sensitization of vascular smooth muscle contraction].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070401

Title: The bioactive lipid sphingosylphosphorylcholine induces differentiation of mouse embryonic stem cells and human promyelocytic leukaemia cells.

Journal: Cellular signalling 20070201

Title: Novel carbonyl and nitrile products from reactive chlorinating species attack of lysosphingolipid.

Journal: Chemistry and physics of lipids 20070201

Title: Vascular abnormalities in mice deficient for the G protein-coupled receptor GPR4 that functions as a pH sensor.

Journal: Molecular and cellular biology 20070201

Title: Sphingosylphosphorylcholine stimulates expression of fibronectin through TGF-beta1-Smad-dependent mechanism in human mesenchymal stem cells.

Journal: The international journal of biochemistry & cell biology 20070101

Title: Sphingosylphosphorylcholine induces differentiation of human mesenchymal stem cells into smooth-muscle-like cells through a TGF-beta-dependent mechanism.

Journal: Journal of cell science 20061201

Title: Sphingosine regulates the transcription of CYP17 by binding to steroidogenic factor-1.

Journal: Endocrinology 20061101

Title: Blebbistatin inhibits sphingosylphosphorylcholine-induced contraction of collagen-gel fiber populated by vascular smooth-muscle cells.

Journal: Journal of pharmacological sciences 20061101

Title: Sphingosylphosphorylcholine enhances calcium entry in thyroid FRO cells by a mechanism dependent on protein kinase C.

Journal: Cellular signalling 20061001

Title: Sphingosylphosphorylcholine stimulates human monocyte-derived dendritic cell chemotaxis.

Journal: Acta pharmacologica Sinica 20061001

Title: Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation.

Journal: American journal of physiology. Heart and circulatory physiology 20060901

Title: Cholesterol primes vascular smooth muscle to induce Ca2 sensitization mediated by a sphingosylphosphorylcholine-Rho-kinase pathway: possible role for membrane raft.

Journal: Circulation research 20060804

Title: Indomethacin differentiates the renal effects of sphingosine-1-phosphate and sphingosylphosphorylcholine.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060401

Title: Augmented sphingosylphosphorylcholine-induced Ca2+-sensitization of mesenteric artery contraction in spontaneously hypertensive rat.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060401

Title: Sphingosylphosphorylcholine-induced ERK activation inhibits melanin synthesis in human melanocytes.

Journal: Pigment cell research 20060401

Title: Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060401

Title: Sphingosylphosphorylcholine induces proliferation of human adipose tissue-derived mesenchymal stem cells via activation of JNK.

Journal: Journal of lipid research 20060301

Title: Retraction. Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.

Journal: Nature cell biology 20060301

Title: Quantitative evaluation of sphingolipids using delayed extraction matrix-assisted laser desorption ionization time-of-flight mass spectrometry with sphingosylphosphorylcholine as an internal standard. Practical application to cardiac valves from a patient with Fabry disease.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217

Title: Sphingosine-1-phosphate and sphingosylphosphorylcholine: two of a kind?

Journal: British journal of pharmacology 20060201

Title: Sphingolipids differentially regulate mitogen-activated protein kinases and intracellular Ca2+ in vascular smooth muscle: effects on CREB activation.

Journal: British journal of pharmacology 20060201

Title: Quantification of the wound healing using polarization-sensitive optical coherence tomography.

Journal: Journal of biomedical optics 20060101

Title: Receptors for protons or lipid messengers or both?

Journal: Journal of receptor and signal transduction research 20060101

Title: Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4.

Journal: The Journal of biological chemistry 20051230

Title: Two ligands for a GPCR, proton vs lysolipid.

Journal: Acta pharmacologica Sinica 20051201

Title: Sphingosylphosphorylcholine-induced vasoconstriction of pulmonary artery: activation of non-store-operated Ca2+ entry.

Journal: Cardiovascular research 20051001

Title: Non-capacitative calcium entry--extension of the possibilities for calcium entry in vascular tissue.

Journal: Cardiovascular research 20051001

Title: Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation.

Journal: Journal of pharmacological sciences 20051001

Title: Human resting CD16-, CD16+ and IL-2-, IL-12-, IL-15- or IFN-alpha-activated natural killer cells differentially respond to sphingosylphosphorylcholine, lysophosphatidylcholine and platelet-activating factor.

Journal: European journal of immunology 20050901

Title: Induction of connective tissue growth factor expression by sphingosylphosphorylcholine in cultured human skin fibroblasts.

Journal: Experimental dermatology 20050701

Title: Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family.

Journal: The Journal of biological chemistry 20050617

Title: Synthesis of a photoactivatable (2S,3R)-sphingosylphosphorylcholine analogue.

Journal: The Journal of organic chemistry 20050610

Title: Sphingosylphosphorylcholine generates reactive oxygen species through calcium-, protein kinase Cdelta- and phospholipase D-dependent pathways.

Journal: Cellular signalling 20050601

Title: Involvement of urokinase-type plasminogen activator in sphingosylphosphorylcholine-induced angiogenesis.

Journal: Experimental dermatology 20050501

Title: GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050501

Title: Role of MEK-ERK pathway in sphingosylphosphorylcholine-induced cell death in human adipose tissue-derived mesenchymal stem cells.

Journal: Biochimica et biophysica acta 20050501

Title: Bioactive lysophospholipids and mesangial cell intracellular signaling pathways: role in the pathobiology of kidney disease.

Journal: Histology and histopathology 20050401

Title: A new fluorimetric enzyme assay for the diagnosis of Niemann-Pick A/B, with specificity of natural sphingomyelinase substrate.

Journal: Journal of inherited metabolic disease 20050101

Title: Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria.

Journal: Acta biomaterialia 20050101

Title: G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine.

Journal: The Journal of biological chemistry 20041008

Title: The influence of zinc on the modulatory effect of sphingosylphosphorylcholine on Kv1.3 channels in human T lymphocytes.

Journal: European biophysics journal : EBJ 20041001

Title: A novel approach for preventing esophageal stricture formation: sphingosylphosphorylcholine-enhanced tissue remodeling.

Journal: Pediatric surgery international 20041001

Title: Novel clusters of receptors for sphingosine-1-phosphate, sphingosylphosphorylcholine, and (lyso)-phosphatidic acid: new receptors for 'old' ligands.

Journal: Journal of cellular biochemistry 20040801

Title: The critical micelle concentrations of lysophosphatidic acid and sphingosylphosphorylcholine.

Journal: Chemistry and physics of lipids 20040701

Title: Comparison of noradrenaline and lysosphingolipid-induced vasoconstriction in mouse and rat small mesenteric arteries.

Journal: Autonomic & autacoid pharmacology 20040701

Title: Signaling events during induction of plasminogen activator inhibitor-1 expression by sphingosylphosphorylcholine in cultured human dermal fibroblasts.

Journal: The Journal of investigative dermatology 20040601

Title: Sphingolipids as bioactive regulators of thrombin generation.

Journal: The Journal of biological chemistry 20040326

Title: Hydrolysis of sphingosylphosphocholine by neutral sphingomyelinases.

Journal: FEBS letters 20040116

Title: Sphingosylphosphorylcholine is a Melanogenic Stimulator for Human Melanocytes.

Journal: Pigment cell research 20031201

Title: Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells.

Journal: Nature cell biology 20030901

Title: Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate.

Journal: Cancer research 20030901

Title: Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.

Journal: The Journal of biological chemistry 20030829

Title: Modulation of spontaneous transmitter release from the frog neuromuscular junction by interacting intracellular Ca(2+) stores: critical role for nicotinic acid-adenine dinucleotide phosphate (NAADP).

Journal: The Biochemical journal 20030715

Title: Extra- and intracellular sphingosylphosphorylcholine promote spontaneous transmitter release from frog motor nerve endings.

Journal: Molecular pharmacology 20030601

Title: Ca2+ and voltage dependence of cardiac ryanodine receptor channel block by sphingosylphosphorylcholine.

Journal: Pflugers Archiv : European journal of physiology 20030301

Title: Sphingosylphosphorylcholine, a naturally occurring lipid mediator, inhibits human platelet function.

Journal: British journal of pharmacology 20030201

Title: Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030201

Title: Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis.

Journal: Journal of lipid research 20030101

Title: Comparison of signalling mechanisms involved in rat mesenteric microvessel contraction by noradrenaline and sphingosylphosphorylcholine.

Journal: British journal of pharmacology 20030101

Title: Sphingosylphosphorylcholine stimulates cellular fibronectin expression through upregulation of IL-6 in cultured human dermal fibroblasts.

Journal: Archives of dermatological research 20030101

Title: Sphingosylphosphorylcholine-induced contraction of feline ileal smooth muscle cells is mediated by Galphai3 protein and MAPK.

Journal: Cellular signalling 20021201

Title: Involvement of Src family protein tyrosine kinases in Ca(2+) sensitization of coronary artery contraction mediated by a sphingosylphosphorylcholine-Rho-kinase pathway.

Journal: Circulation research 20021115

Title: New roads leading to Ca2+ sensitization.

Journal: Circulation research 20020726

Title: Sphingosylphosphorylcholine is a novel messenger for Rho-kinase-mediated Ca2+ sensitization in the bovine cerebral artery: unimportant role for protein kinase C.

Journal: Circulation research 20020726

Title: Sphingosylphosphorylcholine and lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction.

Journal: Biochimica et biophysica acta 20020523

Title: Sphingosylphosphorylcholine-biological functions and mechanisms of action.

Journal: Biochimica et biophysica acta 20020523

Title: Re-evaluation of primary structure, topology, and localization of Scamper, a putative intracellular Ca2+ channel activated by sphingosylphosphocholine.

Journal: The Biochemical journal 20020215

Title: Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4.

Journal: The Journal of biological chemistry 20011102

Title: A role for G protein-coupled lysophospholipid receptors in sphingolipid-induced Ca2+ signaling in MC3T3-E1 osteoblastic cells.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20011101

Title: Sphingosylphosphorylcholine is an activator of transglutaminase activity in human keratinocytes.

Journal: Journal of lipid research 20011001

Title: Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids.

Journal: The Journal of biological chemistry 20010914

Title: Immunology. The push-me pull-you of T cell activation.

Journal: Science (New York, N.Y.) 20010727

Title: Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A.

Journal: Science (New York, N.Y.) 20010727

Title: Lysophospholipids increase interleukin-8 expression in ovarian cancer cells.

Journal: Gynecologic oncology 20010501

Title: Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase.

Journal: Biochemistry 20010424

Title: Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors.

Journal: The Biochemical journal 20010401

Title: Structure activity relationships of lysophospholipid mediators.

Journal: Prostaglandins & other lipid mediators 20010401

Title: Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors.

Journal: European journal of pharmacology 20010302

Title: Sphingolipid derivatives modulate intracellular Ca2+ in rat synaptosomes.

Journal: Acta neurobiologiae experimentalis 20010101

Title: Characterization of a novel sphingosine 1-phosphate receptor, Edg-8.

Journal: The Journal of biological chemistry 20000512

Title: Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.

Journal: Nature cell biology 20000501

Title: Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6.

Journal: Blood 20000415

Title: Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5.

Journal: The Journal of biological chemistry 19990702

Title: EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition.

Journal: The Journal of biological chemistry 19981016

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Tags:82970-80-7 Molecular Formula|82970-80-7 MDL|82970-80-7 SMILES|82970-80-7 LYSO-SPHINGOMYELIN