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83-45-4,MFCD11109453
Catalog No.:AA0053WS

83-45-4 | Stigmastan-3-ol, (3b,5a)-

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1mg
≥95%
in stock  
$63.00   $44.00
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5mg
≥95%
in stock  
$238.00   $166.00
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10mg
≥95%
in stock  
$418.00   $292.00
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25mg
≥95%
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$912.00   $638.00
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100mg
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$3,450.00   $2,415.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0053WS
Chemical Name:
Stigmastan-3-ol, (3b,5a)-
CAS Number:
83-45-4
Molecular Formula:
C29H52O
Molecular Weight:
416.7226
MDL Number:
MFCD11109453
SMILES:
CC[C@@H](C(C)C)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@@H]2[C@]1(C)CC[C@@H](C2)O)C
NSC Number:
49081
Properties
Properties
 
Form:
Solid  
MP:
131-134°C  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
583  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
10.2  

Literature

Title: Dietary plant stanols or sterols neither accumulate in stenotic aortic valves nor influence their structure or inflammatory status.

Journal: Clinical nutrition (Edinburgh, Scotland) 20151201

Title: Evaluation of the effect of plant sterols on the intestinal processing of cholesterol using an in vitro lipolysis model.

Journal: International journal of pharmaceutics 20121015

Title: Origin of fecal contamination in waters from contrasted areas: stanols as Microbial Source Tracking markers.

Journal: Water research 20120901

Title: Serum and lipoprotein sitostanol and non-cholesterol sterols after an acute dose of plant stanol ester on its long-term consumption.

Journal: European journal of nutrition 20120801

Title: Beneficial effects of sitostanol on the attenuated immune function in asthma patients: results of an in vitro approach.

Journal: PloS one 20120101

Title: Properties of β-sitostanol/DPPC monolayers studied with Grazing Incidence X-ray Diffraction (GIXD) and Brewster Angle Microscopy.

Journal: Journal of colloid and interface science 20111201

Title: Current therapy for patients with sitosterolemia--effect of ezetimibe on plant sterol metabolism.

Journal: Journal of atherosclerosis and thrombosis 20100930

Title: Exploratory characterization of the unsaponifiable fraction of tunisian virgin olive oils by a global approach with HPLC-APCI-IT MS/MS analysis.

Journal: Journal of agricultural and food chemistry 20100526

Title: TLR2 activation is essential to induce a Th1 shift in human peripheral blood mononuclear cells by plant stanols and plant sterols.

Journal: The Journal of biological chemistry 20100129

Title: Effect of rapeseed oil-derived plant sterol and stanol esters on atherosclerosis parameters in cholesterol-challenged heterozygous Watanabe heritable hyperlipidaemic rabbits.

Journal: The British journal of nutrition 20091201

Title: Chemometric approach to validating faecal sterols as source tracer for faecal contamination in water.

Journal: Water research 20091201

Title: [Comparison of the dietary phytosterols intake and serum lipids content in elderly women from three cities of China].

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20091201

Title: Lack of genoprotective effect of phytosterols and conjugated linoleic acids on Caco-2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801

Title: Inhibition of intestinal absorption of cholesterol by surface-modified nanostructured aluminosilicate compounds.

Journal: Journal of pharmaceutical sciences 20090701

Title: Plant stanol ester spreads as components of a balanced diet for pregnant and breast-feeding women: evaluation of clinical safety.

Journal: The British journal of nutrition 20090601

Title: [Analysis of phytosterol contents in food plant materials and Chinese traditional medicines].

Journal: Wei sheng yan jiu = Journal of hygiene research 20090301

Title: Dietary phytosterols and phytostanols alter the expression of sterol-regulatory genes in SHRSP and WKY inbred rats.

Journal: Annals of nutrition & metabolism 20090101

Title: Co-administration of berberine and plant stanols synergistically reduces plasma cholesterol in rats.

Journal: Atherosclerosis 20081101

Title: Effects of long-term plant sterol or stanol ester consumption on lipid and lipoprotein metabolism in subjects on statin treatment.

Journal: The British journal of nutrition 20081101

Title: [Studies on ethyl acetate soluble constituents of Huanglian Jiedutang].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

Title: Study of thermodynamic parameters for solubilization of plant sterol and stanol in bile salt micelles.

Journal: Chemistry and physics of lipids 20080801

Title: Cholesterol absorption from the intestine is a major determinant of reverse cholesterol transport from peripheral tissue macrophages.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20080701

Title: Modulation of cytokine production by plant sterols in stimulated human Jurkat T cells.

Journal: Molecular nutrition & food research 20080601

Title: Corn fiber oil and sitostanol decrease cholesterol absorption independently of intestinal sterol transporters in hamsters.

Journal: The Journal of nutritional biochemistry 20080401

Title: Moderately elevated plant sterol levels are associated with reduced cardiovascular risk--the LASA study.

Journal: Atherosclerosis 20080101

Title: Phospholipid transfer protein-deficient mice absorb less cholesterol.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20070901

Title: Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.

Journal: Journal of natural products 20070801

Title: [Analysis of phytosterol contents in Chinese plant food and primary estimation of its intake of people].

Journal: Wei sheng yan jiu = Journal of hygiene research 20070501

Title: Detection of intermittent sewage pollution in a subtropical, oligotrophic, semi-enclosed embayment system using sterol signatures in sediments.

Journal: Environmental science & technology 20070201

Title: Determination of stigmasterol, beta-sitosterol and stigmastanol in oral dosage forms using high performance liquid chromatography with evaporative light scattering detection.

Journal: Journal of pharmaceutical and biomedical analysis 20060607

Title: Plant sterols and stanols: effects on mixed micellar composition and LXR (target gene) activation.

Journal: Journal of lipid research 20051101

Title: Quantitative determination of cholesterol, sitosterol, and sitostanol in cultured Caco-2 cells by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050725

Title: Ratio of lathosterol to campesterol in serum predicts the cholesterol-lowering effect of sitostanol-supplemented margarine.

Journal: International journal of clinical pharmacology and therapeutics 20050701

Title: Effects of sterol structure, temperature, and lipid medium on phytosterol oxidation.

Journal: Journal of agricultural and food chemistry 20041020

Title: Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice.

Journal: Journal of lipid research 20040701

Title: Effect of phytosterols and phytostanols on the solubilization of cholesterol by dietary mixed micelles: an in vitro study.

Journal: Chemistry and physics of lipids 20040201

Title: Can cholesterol absorption be reduced by phytosterols and phytostanols via a cocrystallization mechanism?

Journal: Chemistry and physics of lipids 20040101

Title: Serum and aortic levels of phytosterols in rabbits fed sitosterol or sitostanol ester preparations.

Journal: Lipids 20031101

Title: Analysis of plant sterol and stanol esters in cholesterol-lowering spreads and beverages using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy.

Journal: Journal of agricultural and food chemistry 20030910

Title: Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct versus indirect methodologies.

Journal: Journal of lipid research 20030501

Title: Comparison of the intestinal uptake of cholesterol, plant sterols, and stanols in mice.

Journal: Journal of lipid research 20030301

Title: Non-nutritive bioactive constituents of plants: phytosterols.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20030301

Title: Comparison of the effects of sitostanol, sitostanol acetate, and sitostanol oleate on the inhibition of cholesterol absorption in normolipemic healthy male volunteers. A placebo controlled randomized cross-over study.

Journal: Arzneimittel-Forschung 20030101

Title: Consumption of tall oil-derived phytosterols in a chocolate matrix significantly decreases plasma total and low-density lipoprotein-cholesterol levels.

Journal: The British journal of nutrition 20021101

Title: Increased intestinal ABCA1 expression contributes to the decrease in cholesterol absorption after plant stanol consumption.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801

Title: Improved method for the synthesis of trans-feruloyl-beta-sitostanol.

Journal: Journal of agricultural and food chemistry 20011001

Title: Plant stanol fatty acid esters inhibit cholesterol absorption and hepatic hydroxymethyl glutaryl coenzyme A reductase activity to reduce plasma levels in rabbits.

Journal: Metabolism: clinical and experimental 20010901

Title: Effects of diets enriched with two different plant stanol ester mixtures on plasma ubiquinol-10 and fat-soluble antioxidant concentrations.

Journal: Metabolism: clinical and experimental 20010501

Title: Inhibitory effects of triterpenoids and sterols on human immunodeficiency virus-1 reverse transcriptase.

Journal: Lipids 20010501

Title: The hypocholesterolaemic effects of sitostanol in the guinea pig are in part related to changes in hepatic lipids and lipoprotein composition.

Journal: The British journal of nutrition 20010201

Title: Effects of plant sterols and stanols on lipid metabolism and cardiovascular risk.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20010201

Title: Assessing plasma pharmacokinetics of cholesterol following oral coadministration with a novel vegetable stanol mixture to fasting rats.

Journal: Journal of pharmaceutical sciences 20010101

Title: Fatty acid steryl, stanyl, and steroid esters by esterification and transesterification in vacuo using Candida rugosa lipase as catalyst.

Journal: Journal of agricultural and food chemistry 20010101

Title: [Plants sterols and stanols: new prospects in prevention of ischemic heart disease (based on data published in the European Heart Journal, 1999, vol. 1 (Suppl S))].

Journal: Terapevticheskii arkhiv 20010101

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