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83-79-4,MFCD09025614
Catalog No.:AA0036BP

83-79-4 | Rotenone

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1g
98%(HPLC)
in stock  
$45.00   $32.00
- +
5g
98%
in stock  
$128.00   $90.00
- +
10g
98%
in stock  
$203.00   $142.00
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25g
98%
in stock  
$394.00   $276.00
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100g
98%
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$1,208.00   $846.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0036BP
Chemical Name:
Rotenone
CAS Number:
83-79-4
Molecular Formula:
C23H22O6
Molecular Weight:
394.4172
MDL Number:
MFCD09025614
SMILES:
COc1cc2c(cc1OC)OCC1C2C(=O)c2c(O1)c1CC(Oc1cc2)C(=C)C
UN Number:
2588
Properties
Properties
 
BP:
559.8°C at 760 mmHg  
Form:
Solid  
MP:
159-164 °C  
Refractive Index:
1.4593 (estimate)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
664  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
3  
XLogP3:
4.1  

Literature

Title: Food derived respiratory complex I inhibitors modify the effect of Leber hereditary optic neuropathy mutations.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20181001

Title: Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways.

Journal: Toxicology and applied pharmacology 20180915

Title: Neuroprotective effect of angiotensin-(1-7) against rotenone-induced oxidative damage in CATH.a neurons.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180801

Title: Downregulation of metabotropic glutamate receptor 5 inhibits hepatoma development in a neurotoxin rotenone-induced Parkinson's disease model.

Journal: Toxicology letters 20180515

Title: Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone.

Journal: Archives of toxicology 20180101

Title: Editor's Highlight: Nlrp3 Is Required for Inflammatory Changes and Nigral Cell Loss Resulting From Chronic Intragastric Rotenone Exposure in Mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170901

Title: Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability.

Journal: Toxicology 20170715

Title: Thymoquinone exerts neuroprotective effect in animal model of Parkinson's disease.

Journal: Toxicology letters 20170705

Title: Effects of Inorganic Arsenic, Methylated Arsenicals, and Arsenobetaine on Atherosclerosis in the Mouse Model and the Role of As3mt-Mediated Methylation.

Journal: Environmental health perspectives 20170701

Title: The effects of rotenone-induced toxicity via the NF-κB-iNOS pathway in rat liver.

Journal: Toxicology mechanisms and methods 20170501

Title: Ultrafine carbon particles promote rotenone-induced dopamine neuronal loss through activating microglial NADPH oxidase.

Journal: Toxicology and applied pharmacology 20170501

Title: Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity.

Journal: Toxicology 20170501

Title: Protective role of apigenin on rotenone induced rat model of Parkinson's disease: Suppression of neuroinflammation and oxidative stress mediated apoptosis.

Journal: Chemico-biological interactions 20170501

Title: DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult.

Journal: Toxicology letters 20170405

Title: Rifampicin pre-treatment inhibits the toxicity of rotenone-induced PC12 cells by enhancing sumoylation modification of α-synuclein.

Journal: Biochemical and biophysical research communications 20170325

Title: RNA-Seq Expression Analysis of Enteric Neuron Cells with Rotenone Treatment and Prediction of Regulated Pathways.

Journal: Neurochemical research 20170201

Title: Harmonization of Mangiferin on methylmercury engendered mitochondrial dysfunction.

Journal: Environmental toxicology 20170201

Title: Neonatal rotenone lesions cause onset of hyperactivity during juvenile and adulthood in the rat.

Journal: Toxicology letters 20170115

Title: Antitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo: Roles of apoptotic cell death and H460 tumor xenografts model.

Journal: Environmental toxicology 20170101

Title: Interaction between subclinical doses of the Parkinson's disease associated gene, α-synuclein, and the pesticide, rotenone, precipitates motor dysfunction and nigrostriatal neurodegeneration in rats.

Journal: Behavioural brain research 20170101

Title: Parkinson's disease-like motor and non-motor symptoms in rotenone-treated zebrafish.

Journal: Neurotoxicology 20170101

Title: BAG5 Interacts with DJ-1 and Inhibits the Neuroprotective Effects of DJ-1 to Combat Mitochondrial Oxidative Damage.

Journal: Oxidative medicine and cellular longevity 20170101

Title: Safranal prevents rotenone-induced oxidative stress and apoptosis in an in vitro model of Parkinson's disease through regulating Keap1/Nrf2 signaling pathway.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20161230

Title: Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson's Disease.

Journal: Neurochemical research 20161101

Title: From the Cover: Alterations in Optineurin Expression and Localization in Pre-clinical Parkinson's Disease Models.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20161001

Title: Neuroprotective effects of pyrroloquinoline quinone against rotenone injury in primary cultured midbrain neurons and in a rat model of Parkinson's disease.

Journal: Neuropharmacology 20160901

Title: Upregulation of the cannabinoid CB2 receptor in environmental and viral inflammation-driven rat models of Parkinson's disease.

Journal: Experimental neurology 20160901

Title: SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model.

Journal: Neurochemical research 20160701

Title: Ameliorative Effect of Quercetin on Neurochemical and Behavioral Deficits in Rotenone Rat Model of Parkinson's Disease: Modulating Autophagy (Quercetin on Experimental Parkinson's Disease).

Journal: Journal of biochemical and molecular toxicology 20160701

Title: Previously Unclassified Mutation of mtDNA m.3472T>C: Evidence of Pathogenicity in Leber's Hereditary Optic Neuropathy.

Journal: Biochemistry. Biokhimiia 20160701

Title: 20C, a bibenzyl compound isolated from Gastrodia elata, protects PC12 cells against rotenone-induced apoptosis via activation of the Nrf2/ARE/HO-1 signaling pathway.

Journal: Acta pharmacologica Sinica 20160601

Title: Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease.

Journal: Chemico-biological interactions 20160505

Title: Downregulation of miR-384-5p attenuates rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through inhibiting endoplasmic reticulum stress.

Journal: American journal of physiology. Cell physiology 20160501

Title: Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease.

Journal: Neurotoxicology 20160501

Title: Tracking micro-optical resonances for identifying and sensing novel procaspase-3 protein marker released from cell cultures in response to toxins.

Journal: Nanotechnology 20160422

Title: Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson's Disease: Modulation of Mitochondrial Perturbations.

Journal: Molecular neurobiology 20160301

Title: Expression changes of genes associated with apoptosis and survival processes in Parkinson's disease.

Journal: Neuroscience letters 20160226

Title: Endoplasmic Reticulum Stress Plays a Key Role in Rotenone-Induced Apoptotic Death of Neurons.

Journal: Molecular neurobiology 20160101

Title: Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20160101

Title: Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism.

Journal: Neurotoxicology 20160101

Title: Resveratrol Regulates Mitochondrial Biogenesis and Fission/Fusion to Attenuate Rotenone-Induced Neurotoxicity.

Journal: Oxidative medicine and cellular longevity 20160101

Title: Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis.

Journal: Scientific reports 20160101

Title: Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration.

Journal: Nature communications 20160101

Title: Enhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction.

Journal: PloS one 20160101

Title: Suppressed translation and ULK1 degradation as potential mechanisms of autophagy limitation under prolonged starvation.

Journal: Autophagy 20160101

Title: L10P mutation in DJ-1 gene induced oxidative stress and mitochondrial disfunction.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20151201

Title: Pyrroloquinoline quinone-conferred neuroprotection in rotenone models of Parkinson's disease.

Journal: Toxicology letters 20151104

Title: Rifampicin attenuates rotenone-induced inflammation via suppressing NLRP3 inflammasome activation in microglia.

Journal: Brain research 20151005

Title: An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.

Journal: The Journal of biological chemistry 20150821

Title: Synthesis and Evaluation of a Novel Deguelin Derivative, L80, which Disrupts ATP Binding to the C-terminal Domain of Heat Shock Protein 90.

Journal: Molecular pharmacology 20150801

Title: Rotenone affects p53 transcriptional activity and apoptosis via targeting SIRT1 and H3K9 acetylation in SH-SY5Y cells.

Journal: Journal of neurochemistry 20150801

Title: Sestrin2 Protects Dopaminergic Cells against Rotenone Toxicity through AMPK-Dependent Autophagy Activation.

Journal: Molecular and cellular biology 20150801

Title: shRNA targeting α-synuclein prevents neurodegeneration in a Parkinson's disease model.

Journal: The Journal of clinical investigation 20150701

Title: Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601

Title: Pyrroloquinoline quinone (PQQ) producing Escherichia coli Nissle 1917 (EcN) alleviates age associated oxidative stress and hyperlipidemia, and improves mitochondrial function in ageing rats.

Journal: Experimental gerontology 20150601

Title: Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells.

Journal: Chemical research in toxicology 20150518

Title: GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway.

Journal: Toxicology letters 20150505

Title: Methylmercury impairs canonical dopamine metabolism in rat undifferentiated pheochromocytoma (PC12) cells by indirect inhibition of aldehyde dehydrogenase.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150401

Title: Cholesteryl ester-transfer protein inhibitors stimulate aldosterone biosynthesis in adipocytes through Nox-dependent processes.

Journal: The Journal of pharmacology and experimental therapeutics 20150401

Title: The molecular mechanism of rotenone-induced α-synuclein aggregation: emphasizing the role of the calcium/GSK3β pathway.

Journal: Toxicology letters 20150304

Title: JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death.

Journal: Toxicology 20150203

Title: Deguelin, a selective silencer of the NPM1 mutant, potentiates apoptosis and induces differentiation in AML cells carrying the NPM1 mutation.

Journal: Annals of hematology 20150201

Title: Daily rhythms of serotonin metabolism and the expression of clock genes in suprachiasmatic nucleus of rotenone-induced Parkinson's disease male Wistar rat model and effect of melatonin administration.

Journal: Biogerontology 20150201

Title: Saxagliptin: a novel antiparkinsonian approach.

Journal: Neuropharmacology 20150201

Title: Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease.

Journal: Environment international 20150201

Title: Biomolecular characterization of exosomes released from cancer stem cells: Possible implications for biomarker and treatment of cancer.

Journal: Oncotarget 20150201

Title: Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism.

Journal: Experimental neurology 20150101

Title: Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150101

Title: Angiotensin AT2 receptor stimulation inhibits activation of NADPH oxidase and ameliorates oxidative stress in rotenone model of Parkinson's disease in CATH.a cells.

Journal: Neurotoxicology and teratology 20150101

Title: Neuroprotective effects of bee venom acupuncture therapy against rotenone-induced oxidative stress and apoptosis.

Journal: Neurochemistry international 20150101

Title: Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease.

Journal: Scientific reports 20150101

Title: Deguelin inhibits the migration and invasion of lung cancer A549 and H460 cells via regulating actin cytoskeleton rearrangement.

Journal: International journal of clinical and experimental pathology 20150101

Title: Ellagic acid mitigates SNO-PDI induced aggregation of Parkinsonian biomarkers.

Journal: ACS chemical neuroscience 20141217

Title: Cell therapy using retinal progenitor cells shows therapeutic effect in a chemically-induced rotenone mouse model of Leber hereditary optic neuropathy.

Journal: European journal of human genetics : EJHG 20141101

Title: Deguelin inhibits the migration and invasion of U-2 OS human osteosarcoma cells via the inhibition of matrix metalloproteinase-2/-9 in vitro.

Journal: Molecules (Basel, Switzerland) 20141015

Title: Overexpression of human E46K mutant α-synuclein impairs macroautophagy via inactivation of JNK1-Bcl-2 pathway.

Journal: Molecular neurobiology 20141001

Title: Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20140916

Title: Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells.

Journal: Neurotoxicology 20140901

Title: Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type.

Journal: Biochemical and biophysical research communications 20140822

Title: [Protective effect of baicalin against rotenone induced injury on PC12 cells].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20140801

Title: RTP801 regulates maneb- and mancozeb-induced cytotoxicity via NF-κB.

Journal: Journal of biochemical and molecular toxicology 20140701

Title: Rotenone, a mitochondrial respiratory complex I inhibitor, ameliorates lipopolysaccharide/D-galactosamine-induced fulminant hepatitis in mice.

Journal: International immunopharmacology 20140701

Title: Involvement of ERK1/2 pathway in neuroprotective effects of pyrroloquinoline quinine against rotenone-induced SH-SY5Y cell injury.

Journal: Neuroscience 20140613

Title: Dopamine down-regulation of protein L-isoaspartyl methyltransferase is dependent on reactive oxygen species in SH-SY5Y cells.

Journal: Neuroscience 20140516

Title: Natural pesticide dihydrorotenone arrests human plasma cancer cells at the G0/G1 phase of the cell cycle.

Journal: Journal of biochemical and molecular toxicology 20140501

Title: Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+).

Journal: Cell death & disease 20140501

Title: PPARγ activation rescues mitochondrial function from inhibition of complex I and loss of PINK1.

Journal: Experimental neurology 20140301

Title: TNF-α mediates mitochondrial uncoupling and enhances ROS-dependent cell migration via NF-κB activation in liver cells.

Journal: FEBS letters 20140103

Title: Dietary fat intake, pesticide use, and Parkinson's disease.

Journal: Parkinsonism & related disorders 20140101

Title: Resveratrol partially prevents rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through induction of heme oxygenase-1 dependent autophagy.

Journal: International journal of molecular sciences 20140101

Title: BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation.

Journal: PloS one 20140101

Title: Rifampicin protects PC12 cells from rotenone-induced cytotoxicity by activating GRP78 via PERK-eIF2α-ATF4 pathway.

Journal: PloS one 20140101

Title: Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription.

Journal: Cell 20131205

Title: Release of targeted p53 from the mitochondrion as an early signal during mitochondrial dysfunction.

Journal: Cellular signalling 20131201

Title: Rotenone-induced oxidative stress and apoptosis in human liver HepG2 cells.

Journal: Molecular and cellular biochemistry 20131201

Title: Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131201

Title: Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101

Title: 14-3-3 Proteins in the regulation of rotenone-induced neurotoxicity might be via its isoform 14-3-3epsilon's involvement in autophagy.

Journal: Cellular and molecular neurobiology 20131101

Title: Rotenone induces neuronal death by microglial phagocytosis of neurons.

Journal: The FEBS journal 20131001

Title: Complex I inhibition in the visual pathway induces disorganization of the node of Ranvier.

Journal: Neurobiology of disease 20131001

Title: Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells.

Journal: Nature cell biology 20131001

Title: Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model.

Journal: Oncogene 20130822

Title: The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells.

Journal: European journal of immunology 20130801

Title: Rotenone could activate microglia through NFκB associated pathway.

Journal: Neurochemical research 20130801

Title: Gastrodin ameliorates Parkinson's disease by downregulating connexin 43.

Journal: Molecular medicine reports 20130801

Title: Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster.

Journal: Neurotoxicology 20130701

Title: Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes.

Journal: Experimental & molecular medicine 20130701

Title: Chronic oxidative stress modulates TRPC3 and TRPM2 channel expression and function in rat primary cortical neurons: relevance to the pathophysiology of bipolar disorder.

Journal: Brain research 20130623

Title: Neonatal exposure to lipopolysaccharide enhances accumulation of α-synuclein aggregation and dopamine transporter protein expression in the substantia nigra in responses to rotenone challenge in later life.

Journal: Toxicology 20130607

Title: Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression.

Journal: Journal of agricultural and food chemistry 20130605

Title: Relative expression of cholesterol transport-related proteins and inflammation markers through the induction of 7-ketosterol-mediated stress in Caco-2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130601

Title: MCJ/DnaJC15, an endogenous mitochondrial repressor of the respiratory chain that controls metabolic alterations.

Journal: Molecular and cellular biology 20130601

Title: Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130601

Title: MicroRNA-195 targets ADP-ribosylation factor-like protein 2 to induce apoptosis in human embryonic stem cell-derived neural progenitor cells.

Journal: Cell death & disease 20130601

Title: Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats.

Journal: Neuroscience 20130416

Title: The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats.

Journal: Behavioural brain research 20130415

Title: Gene expression profiling of rotenone-mediated cortical neuronal death: evidence for inhibition of ubiquitin-proteasome system and autophagy-lysosomal pathway, and dysfunction of mitochondrial and calcium signaling.

Journal: Neurochemistry international 20130401

Title: Rotenone-dependent changes of anterograde motor protein expression and mitochondrial mobility in brain areas related to neurodegenerative diseases.

Journal: Cellular and molecular neurobiology 20130401

Title: Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2.

Journal: Cell death & disease 20130401

Title: A DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine, exacerbates neurotoxicity and upregulates Parkinson's disease-related genes in dopaminergic neurons.

Journal: CNS neuroscience & therapeutics 20130301

Title: Expression of human E46K-mutated α-synuclein in BAC-transgenic rats replicates early-stage Parkinson's disease features and enhances vulnerability to mitochondrial impairment.

Journal: Experimental neurology 20130201

Title: Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone.

Journal: Journal of neurochemistry 20130201

Title: The mechanism of alternative splicing of the X-linked NDUFB11 gene of the respiratory chain complex I, impact of rotenone treatment in neuroblastoma cells.

Journal: Biochimica et biophysica acta 20130201

Title: Rotenone-induced neurotoxicity in rat brain areas: a study on neuronal and neuronal supportive cells.

Journal: Neuroscience 20130129

Title: Therapeutic effects of human mesenchymal and hematopoietic stem cells on rotenone-treated parkinsonian mice.

Journal: Journal of neuroscience research 20130101

Title: Use of transgenic GFP reporter strains of the nematode Caenorhabditis elegans to investigate the patterns of stress responses induced by pesticides and by organic extracts from agricultural soils.

Journal: Ecotoxicology (London, England) 20130101

Title: Resveratrol confers protection against rotenone-induced neurotoxicity by modulating myeloperoxidase levels in glial cells.

Journal: PloS one 20130101

Title: Rotenone upregulates alpha-synuclein and myocyte enhancer factor 2D independently from lysosomal degradation inhibition.

Journal: BioMed research international 20130101

Title: Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants.

Journal: Journal of neuroscience research 20121201

Title: Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells.

Journal: Free radical research 20121201

Title: RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy.

Journal: International immunopharmacology 20121201

Title: Environmental toxicants as extrinsic epigenetic factors for parkinsonism: studies employing transgenic C. elegans model.

Journal: CNS & neurological disorders drug targets 20121201

Title: ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons.

Journal: Human molecular genetics 20121115

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Evidence for synergism between cell death mechanisms in a cellular model of neurodegeneration in Parkinson's disease.

Journal: Neurotoxicity research 20121101

Title: Deguelin, an Akt inhibitor, down-regulates NF-κB signaling and induces apoptosis in colon cancer cells and inhibits tumor growth in mice.

Journal: Digestive diseases and sciences 20121101

Title: High-energy compounds promote physiological processing of Alzheimer's amyloid-β precursor protein and boost cell survival in culture.

Journal: Journal of neurochemistry 20121101

Title: Cadmium-induced apoptosis in the BJAB human B cell line: involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression.

Journal: Toxicology 20121028

Title: Delivering instilled hydrophobic drug to the bladder by a cationic nanoparticle and thermo-sensitive hydrogel composite system.

Journal: Nanoscale 20121021

Title: DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy.

Journal: Journal of molecular biology 20121019

Title: The neurogenic basic helix-loop-helix transcription factor NeuroD6 enhances mitochondrial biogenesis and bioenergetics to confer tolerance of neuronal PC12-NeuroD6 cells to the mitochondrial stressor rotenone.

Journal: Experimental cell research 20121015

Title: Mitochondrial bioenergetics and drug-induced toxicity in a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms.

Journal: Toxicology and applied pharmacology 20121015

Title: Molecular responses differ between sensitive silver carp and tolerant bighead carp and bigmouth buffalo exposed to rotenone.

Journal: Fish physiology and biochemistry 20121001

Title: Oxidized phospholipids as biomarkers of tissue and cell damage with a focus on cardiolipin.

Journal: Biochimica et biophysica acta 20121001

Title: Detection of ischemic neuronal damage with [¹⁸F]BMS-747158-02, a mitochondrial complex-1 positron emission tomography ligand: small animal PET study in rat brain.

Journal: Synapse (New York, N.Y.) 20121001

Title: Astrocyte activation: a key step in rotenone induced cytotoxicity and DNA damage.

Journal: Neurochemical research 20121001

Title: AIF depletion provides neuroprotection through a preconditioning effect.

Journal: Apoptosis : an international journal on programmed cell death 20121001

Title: Rotenone induces KATP channel opening in PC12 cells in association with the expression of tyrosine hydroxylase.

Journal: Oncology reports 20121001

Title: Rotenone-induced parkinsonism elicits behavioral impairments and differential expression of parkin, heat shock proteins and caspases in the rat.

Journal: Neuroscience 20120918

Title: Effect of a high dose of simvastatin on muscle mitochondrial metabolism and calcium signaling in healthy volunteers.

Journal: Toxicology and applied pharmacology 20120915

Title: A new antifungal and cytotoxic C-methylated flavone glycoside from Picea neoveitchii.

Journal: Bioorganic & medicinal chemistry letters 20120915

Title: Glycogen synthase kinase-3β activation mediates rotenone-induced cytotoxicity with the involvement of microtubule destabilization.

Journal: Biochemical and biophysical research communications 20120914

Title: Rotenone-induced apoptosis and role of calcium: a study on Neuro-2a cells.

Journal: Archives of toxicology 20120901

Title: Administration of rotenone enhanced voluntary alcohol drinking behavior in C57BL/6J mice.

Journal: Legal medicine (Tokyo, Japan) 20120901

Title: Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D.

Journal: Biochimica et biophysica acta 20120901

Title: Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation.

Journal: Journal of neurochemistry 20120901

Title: Role of metabotropic glutamate receptors in the mechanisms of experimental parkinsonism development.

Journal: Bulletin of experimental biology and medicine 20120901

Title: Novel role of PKR in inflammasome activation and HMGB1 release.

Journal: Nature 20120830

Title: Dl-3-n-butylphthalide, a natural antioxidant, protects dopamine neurons in rotenone models for Parkinson's disease.

Journal: Neurobiology of aging 20120801

Title: Mitochondrial complex I inhibitor rotenone-induced toxicity and its potential mechanisms in Parkinson's disease models.

Journal: Critical reviews in toxicology 20120801

Title: Acute exposure to the mitochondrial complex I toxin rotenone impairs synaptic long-term potentiation in rat hippocampal slices.

Journal: CNS neuroscience & therapeutics 20120801

Title: Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation.

Journal: The Journal of biological chemistry 20120720

Title: Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP⁺, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells.

Journal: Neuroscience letters 20120711

Title: Methylene blue protects primary rat retinal ganglion cells from cellular senescence.

Journal: Investigative ophthalmology & visual science 20120710

Title: Selective protection of nigral dopaminergic neurons by echinacoside in a rat model of Parkinson disease induced by rotenone.

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20120701

Title: The joint action of destruxins and botanical insecticides (rotenone, azadirachtin and paeonolum) against the cotton aphid, Aphis gossypii Glover.

Journal: Molecules (Basel, Switzerland) 20120618

Title: Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation.

Journal: Antioxidants & redox signaling 20120615

Title: The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins.

Journal: Brain research 20120612

Title: Neurotoxin-based models of Parkinson's disease.

Journal: Neuroscience 20120601

Title: Peripheral inflammation increases the deleterious effect of CNS inflammation on the nigrostriatal dopaminergic system.

Journal: Neurotoxicology 20120601

Title: Chemical constituents of the aerial part of Derris elliptica.

Journal: Fitoterapia 20120601

Title: Effect of pesticides on the aggregation of mutant huntingtin protein.

Journal: Molecular neurobiology 20120601

Title: Propensity of Selaginella delicatula aqueous extract to offset rotenone-induced oxidative dysfunctions and neurotoxicity in Drosophila melanogaster: Implications for Parkinson's disease.

Journal: Neurotoxicology 20120601

Title: NMDA alters rotenone toxicity in rat substantia nigra zona compacta and ventral tegmental area dopamine neurons.

Journal: Neurotoxicology 20120601

Title: In vitro inhibition of pigmentation and fiber development in colored cotton.

Journal: Journal of Zhejiang University. Science. B 20120601

Title: Screening of anti-cancer agent using zebrafish: comparison with the MTT assay.

Journal: Biochemical and biophysical research communications 20120525

Title: Fish oil prophylaxis attenuates rotenone-induced oxidative impairments and mitochondrial dysfunctions in rat brain.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Title: Mitochondrial respiration in ME-CAM, PEPCK-CAM, and C₃ succulents: comparative operation of the cytochrome, alternative, and rotenone-resistant pathways.

Journal: Journal of experimental botany 20120501

Title: Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: Rotenone-induced death of RGC-5 cells is caspase independent, involves the JNK and p38 pathways and is attenuated by specific green tea flavonoids.

Journal: Neurochemical research 20120501

Title: Rotenone formulation fate in Lake Davis following the 2007 treatment.

Journal: Environmental toxicology and chemistry 20120501

Title: Glutamate-induced free radical formation in rat brain synaptosomes is not dependent on intrasynaptosomal mitochondria membrane potential.

Journal: Neuroscience letters 20120404

Title: Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease.

Journal: Neurobiology of aging 20120401

Title: Behavioral, neurochemical and histological alterations promoted by bilateral intranigral rotenone administration: a new approach for an old neurotoxin.

Journal: Neurotoxicity research 20120401

Title: Bacopa monnieri extract offsets rotenone-induced cytotoxicity in dopaminergic cells and oxidative impairments in mice brain.

Journal: Cellular and molecular neurobiology 20120401

Title: Differing effects of toxicants (methylmercury, inorganic mercury, lead, amyloid β, and rotenone) on cultured rat cerebrocortical neurons: differential expression of rho proteins associated with neurotoxicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120401

Title: Induction of DNA damage by deguelin is mediated through reducing DNA repair genes in human non-small cell lung cancer NCI-H460 cells.

Journal: Oncology reports 20120401

Title: Acute feedback control of astrocytic glycolysis by lactate.

Journal: Glia 20120401

Title: Mitochondrial electron transport and glycolysis are coupled in articular cartilage.

Journal: Osteoarthritis and cartilage 20120401

Title: Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state.

Journal: Biochimica et biophysica acta 20120301

Title: Effects of mitochondrial poisons on the neuropathic pain produced by the chemotherapeutic agents, paclitaxel and oxaliplatin.

Journal: Pain 20120301

Title: Astrocyte mediated protection of fetal cerebral cortical neurons from rotenone and paraquat.

Journal: Environmental toxicology and pharmacology 20120301

Title: Decrease in nicotinamide adenine dinucleotide dehydrogenase is related to skin pigmentation.

Journal: Journal of cosmetic dermatology 20120301

Title: Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder.

Journal: Bipolar disorders 20120301

Title: [Cysteinyl leukotriene receptor 1 is involved in rotenone-induced injury of PC12 cells].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20120301

Title: Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone.

Journal: Neuroscience 20120217

Title: Brown adipose tissue mitochondria: modulation by GDP and fatty acids depends on the respiratory substrates.

Journal: Bioscience reports 20120201

Title: Protective effects of agmatine in rotenone-induced damage of human SH-SY5Y neuroblastoma cells: fourier transform infrared spectroscopy analysis in a model of Parkinson's disease.

Journal: Amino acids 20120201

Title: Different characteristics of reactive oxygen species production by human keratinocyte cell line cells in response to allergens and irritants.

Journal: Experimental dermatology 20120201

Title: Matrix metalloproteinase-3 is activated by HtrA2/Omi in dopaminergic cells: relevance to Parkinson's disease.

Journal: Neurochemistry international 20120201

Title: The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity.

Journal: PLoS genetics 20120201

Title: Regulation by mitochondrial superoxide and NADPH oxidase of cellular formation of nitrated cyclic GMP: potential implications for ROS signalling.

Journal: The Biochemical journal 20120115

Title: Protective effects of baicalein against rotenone-induced neurotoxicity in PC12 cells and isolated rat brain mitochondria.

Journal: European journal of pharmacology 20120115

Title: Synthesis of deguelin-biotin conjugates and investigation into deguelin's interactions.

Journal: Bioorganic & medicinal chemistry 20120115

Title: Mitochondria-derived superoxide and voltage-gated sodium channels in baroreceptor neurons from chronic heart-failure rats.

Journal: Journal of neurophysiology 20120115

Title: Rotenone activates phagocyte NADPH oxidase by binding to its membrane subunit gp91phox.

Journal: Free radical biology & medicine 20120115

Title: [Adenovirus vector mediated human 14-3-3 γ gene transfer protects dopaminergic cells against rotenone-induced injury].

Journal: Zhonghua yi xue za zhi 20120103

Title: Melatonin protects against rotenone-induced cell injury via inhibition of Omi and Bax-mediated autophagy in Hela cells.

Journal: Journal of pineal research 20120101

Title: Gender segregation in gene expression and vulnerability to oxidative stress induced injury in ventral mesencephalic cultures of dopamine neurons.

Journal: Journal of neuroscience research 20120101

Title: Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy.

Journal: Pharmacology, biochemistry, and behavior 20120101

Title: Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limb.

Journal: American journal of physiology. Renal physiology 20120101

Title: Chronic Akt blockade aggravates pathological hypertrophy and inhibits physiological hypertrophy.

Journal: American journal of physiology. Heart and circulatory physiology 20120101

Title: Reactive oxygen species are produced at low glucose and contribute to the activation of AMPK in insulin-secreting cells.

Journal: Free radical biology & medicine 20120101

Title: Tamoxifen subcellular localization; observation of cell-specific cytotoxicity enhancement by inhibition of mitochondrial ETC complexes I and III.

Journal: Photochemistry and photobiology 20120101

Title: A water soluble CoQ10 formulation improves intracellular distribution and promotes mitochondrial respiration in cultured cells.

Journal: PloS one 20120101

Title: Intestinal ischemia-reperfusion increases efflux for uric acid via paracellular route in the intestine, but decreases that via transcellular route mediated by BCRP.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101

Title: Real-time monitoring of superoxide generation and cytotoxicity in neuroblastoma mitochondria induced by 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline.

Journal: Redox report : communications in free radical research 20120101

Title: Deguelin attenuates reperfusion injury and improves outcome after orthotopic lung transplantation in the rat.

Journal: PloS one 20120101

Title: Mitochondria take up Ca2+ in two steps dependently on store-operated Ca2+ entry in mast cells.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis.

Journal: PloS one 20120101

Title: Mitochondrial dysfunction and oxidative stress promote apoptotic cell death in the striatum via cytochrome c/caspase-3 signaling cascade following chronic rotenone intoxication in rats.

Journal: International journal of molecular sciences 20120101

Title: Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death.

Journal: PloS one 20120101

Title: Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy.

Journal: PloS one 20120101

Title: Time-dependent stabilization of hypoxia inducible factor-1α by different intracellular sources of reactive oxygen species.

Journal: PloS one 20120101

Title: Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice.

Journal: Scientific reports 20120101

Title: Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y.

Journal: Neuroscience 20111229

Title: Anticancer efficacy of deguelin in human prostate cancer cells targeting glycogen synthase kinase-3 β/β-catenin pathway.

Journal: International journal of cancer 20111215

Title: Neuroprotection of α-synuclein under acute and chronic rotenone and maneb treatment is abolished by its familial Parkinson's disease mutations A30P, A53T and E46K.

Journal: Neurotoxicology 20111201

Title: Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20111201

Title: Neonatal exposure to lipopolysaccharide enhances vulnerability of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life.

Journal: Neurobiology of disease 20111201

Title: A viability assay for Candida albicans based on the electron transfer mediator 2,6-dichlorophenolindophenol.

Journal: Analytical biochemistry 20111201

Title: High efficiency of energy flux controls within mitochondrial interactosome in cardiac intracellular energetic units.

Journal: Biochimica et biophysica acta 20111201

Title: Antioxidant properties of rare sugar D-allose: Effects on mitochondrial reactive oxygen species production in Neuro2A cells.

Journal: Journal of bioscience and bioengineering 20111201

Title: Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and L-dopa toxicity.

Journal: Neuroscience research 20111201

Title: Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria.

Journal: Biochimica et biophysica acta 20111201

Title: Hypoxia acts through multiple signaling pathways to induce metallothionein transactivation by the metal-responsive transcription factor-1 (MTF-1).

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20111201

Title: The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cells.

Journal: Cancer biology & therapy 20111201

Title: Differential programming of p53-deficient embryonic cells during rotenone block.

Journal: Toxicology 20111128

Title: DJ-1 knock-down impairs astrocyte mitochondrial function.

Journal: Neuroscience 20111124

Title: Dopamine oxidation facilitates rotenone-dependent potentiation of N-methyl-D-aspartate currents in rat substantia nigra dopamine neurons.

Journal: Neuroscience 20111110

Title: The protective effects of inosine against chemical hypoxia on cultured rat oligodendrocytes.

Journal: Cellular and molecular neurobiology 20111101

Title: Ceruloplasmin protects against rotenone-induced oxidative stress and neurotoxicity.

Journal: Neurochemical research 20111101

Title: Environmental impact on vascular development predicted by high-throughput screening.

Journal: Environmental health perspectives 20111101

Title: Myocardial uptake of 7'-(Z)-[(123)I]iodorotenone during vasodilator stress in dogs with critical coronary stenoses.

Journal: Circulation. Cardiovascular imaging 20111101

Title: An effective novel delivery strategy of rasagiline for Parkinson's disease.

Journal: International journal of pharmaceutics 20111031

Title: Rotenone-mediated changes in intracellular coenzyme A thioester levels: implications for mitochondrial dysfunction.

Journal: Chemical research in toxicology 20111017

Title: Knock-down of argonaute 2 (AGO2) induces apoptosis in myeloid leukaemia cells and inhibits siRNA-mediated silencing of transfected oncogenes in HEK-293 cells.

Journal: Basic & clinical pharmacology & toxicology 20111001

Title: Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina.

Journal: Neurobiology of disease 20111001

Title: Neutral sphingomyelinase, NADPH oxidase and reactive oxygen species. Role in acute hypoxic pulmonary vasoconstriction.

Journal: Journal of cellular physiology 20111001

Title: Leaf extract of Rhus verniciflua Stokes protects dopaminergic neuronal cells in a rotenone model of Parkinson's disease.

Journal: The Journal of pharmacy and pharmacology 20111001

Title: Calpain inhibition protected spinal cord motoneurons against 1-methyl-4-phenylpyridinium ion and rotenone.

Journal: Neuroscience 20110929

Title: Glyceraldehyde-3-phosphate dehydrogenase: activity inhibition and protein overexpression in rotenone models for Parkinson's disease.

Journal: Neuroscience 20110929

Title: Dose-dependent loss of motor function after unilateral medial forebrain bundle rotenone lesion in rats: a cautionary note.

Journal: Behavioural brain research 20110912

Title: Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults.

Journal: Nature neuroscience 20110904

Title: Paullinia cupana Mart. var. Sorbilis protects human dopaminergic neuroblastoma SH-SY5Y cell line against rotenone-induced cytotoxicity.

Journal: Human & experimental toxicology 20110901

Title: Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage.

Journal: Biochimica et biophysica acta 20110901

Title: Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death.

Journal: Journal of biosciences 20110901

Title: Isoflurane differentially modulates mitochondrial reactive oxygen species production via forward versus reverse electron transport flow: implications for preconditioning.

Journal: Anesthesiology 20110901

Title: Microplate-based kinetic method for assay of mitochondrial NADH-- and succinate--cytochrome c reductase activities.

Journal: Analytical biochemistry 20110815

Title: Synthesis of rotenoid derivatives with cytotoxic and topoisomerase II inhibitory activities.

Journal: Bioorganic & medicinal chemistry letters 20110815

Title: Exploring the boundaries of additivity: mixtures of NADH: quinone oxidoreductase inhibitors.

Journal: Chemical research in toxicology 20110815

Title: Both stereoselective (R)- and (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline enantiomers protect striatal terminals against rotenone-induced suppression of dopamine release.

Journal: Neurotoxicity research 20110801

Title: Flavanones and rotenoids from the roots of Amorpha fruticosa L. that inhibit bacterial neuraminidase.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801

Title: Role for pAKT in rat urinary bladder with cyclophosphamide (CYP)-induced cystitis.

Journal: American journal of physiology. Renal physiology 20110801

Title: Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease.

Journal: Neuro-Signals 20110801

Title: Oxygen consumption rate of permeabilized cells and isolated mitochondria from pork M. masseter and liver examined fresh and after freeze-thawing at different pH values.

Journal: Journal of food science 20110801

Title: Effects of pioglitazone and retinoic acid in a rotenone model of Parkinson's disease.

Journal: Brain research bulletin 20110715

Title: Insecticidal effect and chemical composition of the volatile oil from Bergenia ligulata.

Journal: Journal of agricultural and food chemistry 20110713

Title: Relative contributions of mitochondria and NADPH oxidase to deoxycorticosterone acetate-salt hypertension in mice.

Journal: Kidney international 20110701

Title: Antifeedant effect of commercial chemicals and plant extracts against Schistocerca americana (Orthoptera: Acrididae) and Diaprepes abbreviatus (Coleoptera: Curculionidae).

Journal: Pest management science 20110701

Title: Role of cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 3 (CRTC3) in the initiation of mitochondrial biogenesis and stress response in liver cells.

Journal: The Journal of biological chemistry 20110624

Title: Mitochondrial uncoupling agents antagonize rotenone actions in rat substantia nigra dopamine neurons.

Journal: Brain research 20110613

Title: High-mobility group box 1 is essential for mitochondrial quality control.

Journal: Cell metabolism 20110608

Title: Effect of mitochondrial complex I inhibition on Fe-S cluster protein activity.

Journal: Biochemical and biophysical research communications 20110603

Title: Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549.

Journal: Nanotoxicology 20110601

Title: Rotenone, paraquat, and Parkinson's disease.

Journal: Environmental health perspectives 20110601

Title: Glucose metabolism in mouse cumulus cells prevents oocyte aging by maintaining both energy supply and the intracellular redox potential.

Journal: Biology of reproduction 20110601

Title: PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons.

Journal: Biochimica et biophysica acta 20110601

Title: Human space exploration the next fifty years.

Journal: McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20110601

Title: Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20110524

Title: Mitochondrial complex I impairment in leukocytes from type 2 diabetic patients.

Journal: Free radical biology & medicine 20110515

Title: Alternative mitochondrial electron transfer as a novel strategy for neuroprotection.

Journal: The Journal of biological chemistry 20110506

Title: Characterisation of a novel model of Parkinson's disease by intra-striatal infusion of the pesticide rotenone.

Journal: Neuroscience 20110505

Title: DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity.

Journal: Journal of neurochemistry 20110501

Title: Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging, superoxide, NADPH oxidase, and p38 MAPK.

Journal: Free radical biology & medicine 20110501

Title: Dopamine D₁ and D₂ receptor subtypes functional regulation in cerebral cortex of unilateral rotenone lesioned Parkinson's rat model: Effect of serotonin, dopamine and norepinephrine.

Journal: Parkinsonism & related disorders 20110501

Title: Reactive oxygen species (ROS) play a critical role in the cAMP-induced activation of Ras and the phosphorylation of ERK1/2 in Leydig cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20110501

Title: Aminoethoxydiphenyl borate and flufenamic acid inhibit Ca2+ influx through TRPM2 channels in rat dorsal root ganglion neurons activated by ADP-ribose and rotenone.

Journal: The Journal of membrane biology 20110501

Title: [Effects of deguelin on proliferation and apoptosis of MCF-7 breast cancer cells by phosphatidylinositol 3-kinase/Akt signaling pathway].

Journal: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20110501

Title: Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei.

Journal: Journal of natural products 20110425

Title: EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines.

Journal: Free radical research 20110401

Title: Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30.

Journal: Hypertension (Dallas, Tex. : 1979) 20110401

Title: Variable responses of small and large human hepatocytes to hypoxia and hypoxia/reoxygenation (H-R).

Journal: FEBS letters 20110323

Title: Over-expression of α-synuclein 98 triggers intracellular oxidative stress and enhances susceptibility to rotenone.

Journal: Neuroscience letters 20110317

Title: Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone.

Journal: Brain research 20110316

Title: Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons.

Journal: The Journal of biological chemistry 20110311

Title: Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model.

Journal: The Journal of cell biology 20110307

Title: Detoxified extract of Rhus verniciflua stokes inhibits rotenone-induced apoptosis in human dopaminergic cells, SH-SY5Y.

Journal: Cellular and molecular neurobiology 20110301

Title: Enhanced formation of methane in plant cell cultures by inhibition of cytochrome c oxidase.

Journal: Plant, cell & environment 20110301

Title: Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart.

Journal: American journal of physiology. Heart and circulatory physiology 20110301

Title: Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism.

Journal: The Journal of endocrinology 20110301

Title: Involvement of p53 in cell death following cell cycle arrest and mitotic catastrophe induced by rotenone.

Journal: Biochimica et biophysica acta 20110301

Title: [Rotenone-induced changes of cysteinyl leukotriene receptor 1 expression in BV2 microglial cells].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110301

Title: [5-lipoxygenase is involved in rotenone-induced injury in PC12 cells].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110301

Title: 'Metabolic reprogramming' in ovarian cancer cells resistant to cisplatin.

Journal: Current cancer drug targets 20110201

Title: The role of mitochondria in the radiation-induced bystander effect in human lymphoblastoid cells.

Journal: Radiation research 20110201

Title: Effect of exposure to the edge signal on oxidative stress in brain cell models.

Journal: Radiation research 20110201

Title: Human dental pulp stem cells protect mouse dopaminergic neurons against MPP+ or rotenone.

Journal: Brain research 20110107

Title: Metformin activates AMP kinase through inhibition of AMP deaminase.

Journal: The Journal of biological chemistry 20110107

Title: Reversal of rotenone-induced dysfunction of astrocytic connexin43 by opening mitochondrial ATP-sensitive potassium channels.

Journal: Cellular and molecular neurobiology 20110101

Title: Activation of STAT1 is required for interferon-alpha-mediated cell death.

Journal: Experimental cell research 20110101

Title: DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy.

Journal: Human molecular genetics 20110101

Title: Agmatine effects on mitochondrial membrane potential and NF-κB activation protect against rotenone-induced cell damage in human neuronal-like SH-SY5Y cells.

Journal: Journal of neurochemistry 20110101

Title: Hydrogel tissue construct-based high-content compound screening.

Journal: Journal of biomolecular screening 20110101

Title: Parkinsonian rotenone mouse model: reevaluation of long-term administration of rotenone in C57BL/6 mice.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Neoechinulin a impedes the progression of rotenone-induced cytotoxicity in PC12 cells.

Journal: Biological & pharmaceutical bulletin 20110101

Title: BmDJ-1 is a key regulator of oxidative modification in the development of the silkworm, Bombyx mori.

Journal: PloS one 20110101

Title: NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels.

Journal: PloS one 20110101

Title: Effect of malate on the development of rotenone-induced brain changes in Wistar and OXYS rats: An MRI study.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20110101

Title: Paraquat- and rotenone-induced models of Parkinson's disease.

Journal: International journal of immunopathology and pharmacology 20110101

Title: Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease.

Journal: PloS one 20110101

Title: 14-3-3theta protects against neurotoxicity in a cellular Parkinson's disease model through inhibition of the apoptotic factor Bax.

Journal: PloS one 20110101

Title: Characterization of the stimulus for reactive oxygen species generation in calcium-overloaded mitochondria.

Journal: Redox report : communications in free radical research 20110101

Title: JNK3-mediated apoptotic cell death in primary dopaminergic neurons.

Journal: Methods in molecular biology (Clifton, N.J.) 20110101

Title: Fluorescence dequenching makes haem-free soluble guanylate cyclase detectable in living cells.

Journal: PloS one 20110101

Title: [Regulation of the mitochondrial ATP-sensitive potassium channel in rat uterus cells by ROS].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101

Title: High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity.

Journal: International journal of molecular sciences 20110101

Title: Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.

Journal: Journal of pharmacological sciences 20110101

Title: The automated FADU-assay, a potential high-throughput in vitro method for early screening of DNA breakage.

Journal: ALTEX 20110101

Title: Development of a high-throughput screening assay for cytoprotective agents in rotenone-induced cell death.

Journal: Analytical biochemistry 20101215

Title: Free tubulin modulates mitochondrial membrane potential in cancer cells.

Journal: Cancer research 20101215

Title: New insights into the superoxide generation sites in bovine heart NADH-ubiquinone oxidoreductase (Complex I): the significance of protein-associated ubiquinone and the dynamic shifting of generation sites between semiflavin and semiquinone radicals.

Journal: Biochimica et biophysica acta 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Energetic metabolism and human sperm motility: impact of CB₁ receptor activation.

Journal: Endocrinology 20101201

Title: Effects of rotenone and other mitochondrial complex I inhibitors on the brine shrimp Artemia.

Journal: Acta biologica Hungarica 20101201

Title: Deguelin--an inhibitor to tumor lymphangiogenesis and lymphatic metastasis by downregulation of vascular endothelial cell growth factor-D in lung tumor model.

Journal: International journal of cancer 20101115

Title: Progressive loss of dopaminergic neurons induced by unilateral rotenone infusion into the medial forebrain bundle.

Journal: Brain research 20101111

Title: Long-term efficacy and safety of human umbilical cord mesenchymal stromal cells in rotenone-induced hemiparkinsonian rats.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20101101

Title: Qo site of mitochondrial complex III is the source of increased superoxide after transient exposure to hydrogen peroxide.

Journal: Journal of molecular and cellular cardiology 20101101

Title: Rotenoids from Lablab purpureus L. and their bioefficacy against human disease vectors.

Journal: Parasitology research 20101101

Title: Dopamine D₁ and D₂ receptor subtypes functional regulation in corpus striatum of unilateral rotenone lesioned Parkinson's rat model: effect of serotonin, dopamine and norepinephrine.

Journal: Neurological research 20101101

Title: Role of mitochondria in contraction and pacemaking in the mouse uterus.

Journal: British journal of pharmacology 20101101

Title: Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells.

Journal: Journal of Asian natural products research 20101101

Title: Dopamine-dependent neurodegeneration in Drosophila models of familial and sporadic Parkinson's disease.

Journal: Neurobiology of disease 20101001

Title: Phenothiazines interfere with dopaminergic neurodegeneration in Caenorhabditis elegans models of Parkinson's disease.

Journal: Neurobiology of disease 20101001

Title: α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment.

Journal: Journal of molecular neuroscience : MN 20101001

Title: Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells.

Journal: Neurochemistry international 20101001

Title: Impaired 3',5'-cyclic adenosine monophosphate-mediated signaling in immediate early responsive gene X-1-deficient vascular smooth muscle cells.

Journal: Hypertension (Dallas, Tex. : 1979) 20101001

Title: Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer.

Journal: Oncology reports 20101001

Title: Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity.

Journal: Journal of bioenergetics and biomembranes 20101001

Title: Glutamine-mediated protection from neuronal cell death depends on mitochondrial activity.

Journal: Neuroscience letters 20100927

Title: Attenuation of rotenone-induced mitochondrial oxidative damage and neurotoxicty in Drosophila melanogaster supplemented with creatine.

Journal: Neurochemical research 20100901

Title: Association of dopamine DA-D2 receptor in rotenone-induced cytotoxicity in PC12 cells.

Journal: Toxicology and industrial health 20100901

Title: [Some bio-chemical indice change of rats striatum poisoned by rotenone].

Journal: Wei sheng yan jiu = Journal of hygiene research 20100901

Title: Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100823

Title: Depressive-like behaviors alterations induced by intranigral MPTP, 6-OHDA, LPS and rotenone models of Parkinson's disease are predominantly associated with serotonin and dopamine.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20100816

Title: Transgenic mice overexpressing methionine sulfoxide reductase A: characterization of embryonic fibroblasts.

Journal: Free radical biology & medicine 20100815

Title: The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor.

Journal: Bioorganic & medicinal chemistry 20100815

Title: Respiration in adipocytes is inhibited by reactive oxygen species.

Journal: Obesity (Silver Spring, Md.) 20100801

Title: Rotenone prevents impact-induced chondrocyte death.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20100801

Title: Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes.

Journal: Biochimica et biophysica acta 20100801

Title: [Separation and preparation of two rotenoids from the roots of Derris by high-speed counter-current chromatography].

Journal: Se pu = Chinese journal of chromatography 20100801

Title: Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives.

Journal: Journal of medicinal chemistry 20100722

Title: Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.

Journal: Cancer letters 20100701

Title: Hexokinase II gene transfer protects against neurodegeneration in the rotenone and MPTP mouse models of Parkinson's disease.

Journal: Journal of neuroscience research 20100701

Title: Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats.

Journal: Cellular and molecular neurobiology 20100701

Title: Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20100701

Title: Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors.

Journal: Journal of neurochemistry 20100701

Title: 4-Nitrobenzoate inhibits coenzyme Q biosynthesis in mammalian cell cultures.

Journal: Nature chemical biology 20100701

Title: [Protective effect of over-expression OGCP on HEK293 cells treated by rotenone and mutant Parkin protein].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701

Title: Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation.

Journal: Antioxidants & redox signaling 20100615

Title: A study to correlate rotenone induced biochemical changes and cerebral damage in brain areas with neuromuscular coordination in rats.

Journal: Toxicology 20100604

Title: Mitochondrial development and the influence of its dysfunction during rat adipocyte differentiation.

Journal: Molecular biology reports 20100601

Title: Rotenone enhances the antifungal properties of staurosporine.

Journal: Eukaryotic cell 20100601

Title: Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule?

Journal: Nephron. Physiology 20100601

Title: Measurement of intrinsic physiological membrane noise in cultured living cells.

Journal: Electromagnetic biology and medicine 20100601

Title: The alternative medicine pawpaw and its acetogenin constituents suppress tumor angiogenesis via the HIF-1/VEGF pathway.

Journal: Journal of natural products 20100528

Title: Photolabile ubiquinone analogues for identification and characterization of quinone binding sites in proteins.

Journal: Bioorganic & medicinal chemistry 20100515

Title: Synthesis and evaluation of verticipyrone analogues as mitochondrial complex I inhibitors.

Journal: Bioorganic & medicinal chemistry 20100515

Title: Chronic administration with rotenone does not enhance MPTP neurotoxicity in C57BL/6 mice.

Journal: Journal of molecular neuroscience : MN 20100501

Title: Cytochrome c is rapidly reduced in the cytosol after mitochondrial outer membrane permeabilization.

Journal: Apoptosis : an international journal on programmed cell death 20100501

Title: Molecular mechanisms of methylmercury-induced cell death in human HepG2 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100501

Title: Bioactivity-guided isolation of mosquitocidal constituents from the rhizomes of Plumbago capensis Thunb.

Journal: Bioorganic & medicinal chemistry letters 20100501

Title: JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron death.

Journal: Journal of neuropathology and experimental neurology 20100501

Title: Dual effects of alpha-synuclein on neurotoxicity induced by low dosage of rotenone are dependent on exposure time in dopaminergic neuroblastoma cells.

Journal: Science China. Life sciences 20100501

Title: Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.

Journal: Circulation research 20100416

Title: Neuroprotective effects of hydrogen sulfide on Parkinson's disease rat models.

Journal: Aging cell 20100401

Title: Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100401

Title: Energy conservation by Rhodothermus marinus respiratory complex I.

Journal: Biochimica et biophysica acta 20100401

Title: Decylubiquinone increases mitochondrial function in synaptosomes.

Journal: The Journal of biological chemistry 20100319

Title: Reactive oxygen species (ROS) in the human neocortex: role of aging and cognition.

Journal: Brain research bulletin 20100316

Title: Gene therapy using lactoferrin-modified nanoparticles in a rotenone-induced chronic Parkinson model.

Journal: Journal of the neurological sciences 20100315

Title: Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.

Journal: Chemical research in toxicology 20100315

Title: Autophagy protects the rotenone-induced cell death in alpha-synuclein overexpressing SH-SY5Y cells.

Journal: Neuroscience letters 20100312

Title: Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation.

Journal: Biochimica et biophysica acta 20100301

Title: Deguelin suppresses cell proliferation via the inhibition of survivin expression and STAT3 phosphorylation in HTLV-1-transformed T cells.

Journal: Leukemia research 20100301

Title: Inhibition of osteoclast differentiation and bone resorption by rotenone, through down-regulation of RANKL-induced c-Fos and NFATc1 expression.

Journal: Bone 20100301

Title: The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease.

Journal: Synapse (New York, N.Y.) 20100301

Title: Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation.

Journal: Mitochondrion 20100301

Title: Carnosine protects against permanent cerebral ischemia in histidine decarboxylase knockout mice by reducing glutamate excitotoxicity.

Journal: Free radical biology & medicine 20100301

Title: MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2.

Journal: Journal of neurochemistry 20100301

Title: Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation.

Journal: Molecular and cellular biology 20100301

Title: Dexamethasone and the inflammatory response in explants of human omental adipose tissue.

Journal: Molecular and cellular endocrinology 20100205

Title: Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein.

Journal: Neurotoxicity research 20100201

Title: Melatonin treatment potentiates neurodegeneration in a rat rotenone Parkinson's disease model.

Journal: Journal of neuroscience research 20100201

Title: Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling.

Journal: Molecular carcinogenesis 20100201

Title: Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease.

Journal: Free radical biology & medicine 20100201

Title: Enhanced metallothionein gene expression induced by mitochondrial oxidative stress is reduced in phospholipid hydroperoxide glutathione peroxidase-overexpressed cells.

Journal: European journal of pharmacology 20100125

Title: Synphilin-1 exhibits trophic and protective effects against Rotenone toxicity.

Journal: Neuroscience 20100120

Title: Comparison of methods for measuring oxygen consumption in tumor cells in vitro.

Journal: Analytical biochemistry 20100115

Title: Effects of epigallocatechin gallate on rotenone-injured murine brain cultures.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20100101

Title: In vitro cell-toxicity screening as an alternative animal model for coral toxicology: effects of heat stress, sulfide, rotenone, cyanide, and cuprous oxide on cell viability and mitochondrial function.

Journal: Ecotoxicology (London, England) 20100101

Title: Electrophysiological actions of zonisamide on striatal neurons: Selective neuroprotection against complex I mitochondrial dysfunction.

Journal: Experimental neurology 20100101

Title: Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L).

Journal: Cancer biology & therapy 20100101

Title: The effect of antiparkinsonian drugs on oxidative stress induced pathological [3H]dopamine efflux after in vitro rotenone exposure in rat striatal slices.

Journal: Neuropharmacology 20100101

Title: The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100101

Title: Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models.

Journal: Disease models & mechanisms 20100101

Title: Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice.

Journal: PloS one 20100101

Title: Minocycline protects dopaminergic neurons against long-term rotenone toxicity.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100101

Title: Fusion of the endoplasmic reticulum and mitochondrial outer membrane in rats brown adipose tissue: activation of thermogenesis by Ca2+.

Journal: PloS one 20100101

Title: Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro.

Journal: PloS one 20100101

Title: Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

Journal: Journal of cellular and molecular medicine 20100101

Title: Animal models of neurological disease.

Journal: Advances in experimental medicine and biology 20100101

Title: Successful amelioration of mitochondrial optic neuropathy using the yeast NDI1 gene in a rat animal model.

Journal: PloS one 20100101

Title: Effects of mitochondrial dysfunction on the immunological properties of microglia.

Journal: Journal of neuroinflammation 20100101

Title: Neurotoxic in vivo models of Parkinson's disease recent advances.

Journal: Progress in brain research 20100101

Title: Protein aggregation containing β-amyloid, α-synuclein and hyperphosphorylated τ in cultured cells of hippocampus, substantia nigra and locus coeruleus after rotenone exposure.

Journal: BMC neuroscience 20100101

Title: Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease.

Journal: Cell death & disease 20100101

Title: HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells.

Journal: Neuroscience letters 20091231

Title: Rotenone induces cell death of cholinergic neurons in an organotypic co-culture brain slice model.

Journal: Neurochemical research 20091201

Title: An integrated cellular model to evaluate cytotoxic effects in mammalian cell lines.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20091201

Title: Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice.

Journal: Neurochemistry international 20091201

Title: Rapamycin protects against rotenone-induced apoptosis through autophagy induction.

Journal: Neuroscience 20091201

Title: Evidence for aerobic metabolism in retinal rod outer segment disks.

Journal: The international journal of biochemistry & cell biology 20091201

Title: Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity.

Journal: American journal of physiology. Cell physiology 20091201

Title: Isotope dilution method for the assay of rotenone in olive oil and river waters by liquid chromatography/multiple reaction monitoring tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20091201

Title: Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease.

Journal: Human molecular genetics 20091115

Title: Effect of centrophenoxine against rotenone-induced oxidative stress in an animal model of Parkinson's disease.

Journal: Neurochemistry international 20091101

Title: Protective effect of histamine H2 receptor antagonist ranitidine against rotenone-induced apoptosis.

Journal: Neurotoxicology 20091101

Title: Neuroprotective efficacy of Bacopa monnieri against rotenone induced oxidative stress and neurotoxicity in Drosophila melanogaster.

Journal: Neurotoxicology 20091101

Title: Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20091101

Title: Pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione derivatives: their cytoprotection effect from rotenone toxicity and preliminary DMPK properties.

Journal: Bioorganic & medicinal chemistry letters 20091101

Title: Deguelin inhibits growth of breast cancer cells by modulating the expression of key members of the Wnt signaling pathway.

Journal: Cancer prevention research (Philadelphia, Pa.) 20091101

Title: A novel look into estrogen receptor-negative breast cancer prevention with the natural, multifunctional signal transduction inhibitor deguelin.

Journal: Cancer prevention research (Philadelphia, Pa.) 20091101

Title: Acute action of rotenone on nigral dopaminergic neurons--involvement of reactive oxygen species and disruption of Ca2+ homeostasis.

Journal: The European journal of neuroscience 20091101

Title: Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment.

Journal: Neuroscience 20091020

Title: Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism.

Journal: Biochemical and biophysical research communications 20091016

Title: Effects of glutamate and alpha2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats.

Journal: Toxicology and applied pharmacology 20091015

Title: Deleterious versus neuroprotective effect of metabolic inhibition after traumatic spinal cord injury.

Journal: Spinal cord 20091001

Title: Rotenone partially reverses decreased BK Ca currents in cerebral artery smooth muscle cells from streptozotocin-induced diabetic mice.

Journal: Clinical and experimental pharmacology & physiology 20091001

Title: Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease.

Journal: Neurotoxicity research 20091001

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Reactive oxygen species potentiate the P2X2 receptor activity through intracellular Cys430.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090930

Title: Hypoxia up-regulates CD36 expression and function via hypoxia-inducible factor-1- and phosphatidylinositol 3-kinase-dependent mechanisms.

Journal: The Journal of biological chemistry 20090925

Title: A novel decoy that interrupts G93A-superoxide dismutase gain of interaction with malate dehydrogenase improves survival in an amyotrophic lateral sclerosis cell model.

Journal: Journal of medicinal chemistry 20090910

Title: Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909

Title: Direct, real-time monitoring of superoxide generation in isolated mitochondria.

Journal: Free radical research 20090901

Title: Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?

Journal: Trends in pharmacological sciences 20090901

Title: Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS).

Journal: Aging 20090901

Title: Neurons express hemoglobin alpha- and beta-chains in rat and human brains.

Journal: The Journal of comparative neurology 20090810

Title: Tranexamic acid protects against rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells.

Journal: Toxicology 20090803

Title: Mitochondrial calcium transport and mitochondrial dysfunction after global brain ischemia in rat hippocampus.

Journal: Neurochemical research 20090801

Title: Pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione derivatives as novel small molecule chaperone amplifiers.

Journal: Bioorganic & medicinal chemistry letters 20090801

Title: Hypoxia induces B-type natriuretic peptide release in cell lines derived from human cardiomyocytes.

Journal: American journal of physiology. Heart and circulatory physiology 20090801

Title: Rapid analysis of organic farming insecticides in soil and produce using ultra-performance liquid chromatography/tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20090801

Title: Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric alpha-synuclein.

Journal: The American journal of pathology 20090801

Title: Reactive oxygen species and p38 mitogen-activated protein kinase induce apoptotic death of U937 cells in response to Naja nigricollis toxin-gamma.

Journal: Journal of cellular and molecular medicine 20090801

Title: LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090722

Title: Pigment epithelium derived factor (PEDF) is neuroprotective in two in vitro models of Parkinson's disease.

Journal: Neuroscience letters 20090717

Title: Protected cyanohydrins in the synthesis of rotenoids: (+/-)-munduserone and (+/-)-cis-12a-hydroxymunduserone.

Journal: The Journal of organic chemistry 20090717

Title: Mitochondria are the source of hydrogen peroxide for dynamic brain-cell signaling.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090715

Title: Involvement of glyceraldehyde-3-phosphate dehydrogenase in rotenone-induced cell apoptosis: relevance to protein misfolding and aggregation.

Journal: Brain research 20090707

Title: Vascular pathology in male Lewis rats following short-term, low-dose rotenone administration.

Journal: Veterinary pathology 20090701

Title: Gene expression profiling identifies a role for CHOP during inhibition of the mitochondrial respiratory chain.

Journal: Journal of biochemistry 20090701

Title: Antifeedant activity of ethanolic extract from Flourensia oolepis and isolation of pinocembrin as its active principle compound.

Journal: Bioresource technology 20090701

Title: Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease.

Journal: Experimental neurology 20090701

Title: Mitochondrial electron transport chain blockers enhance 2-deoxy-D-glucose induced oxidative stress and cell killing in human colon carcinoma cells.

Journal: Cancer biology & therapy 20090701

Title: Combining 2-deoxy-D-glucose with electron transport chain blockers: a double-edged sword.

Journal: Cancer biology & therapy 20090701

Title: Behavioral and quantitative mitochondrial proteome analyses of the effects of simvastatin: implications for models of neural degeneration.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20090701

Title: Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruption.

Journal: Neurotoxicology 20090701

Title: Terretonins E and F, inhibitors of the mitochondrial respiratory chain from the marine-derived fungus Aspergillus insuetus (#).

Journal: Journal of natural products 20090701

Title: Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins.

Journal: Brain research bulletin 20090630

Title: Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions.

Journal: The Journal of biological chemistry 20090612

Title: Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence.

Journal: Journal of cellular and molecular medicine 20090601

Title: A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease.

Journal: Neurobiology of disease 20090601

Title: Mitochondrial impacts of insecticidal formate esters in insecticide-resistant and insecticide-susceptible Drosophila melanogaster.

Journal: Pest management science 20090601

Title: Involvement of SRC-3 in deguelin-induced apoptosis in Jurkat cells.

Journal: International journal of hematology 20090601

Title: Deguelin blocks cells survival signal pathways and induces apoptosis of HL-60 cells in vitro.

Journal: International journal of hematology 20090601

Title: Glutathione S-transferase pi localizes in mitochondria and protects against oxidative stress.

Journal: Free radical biology & medicine 20090515

Title: Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species.

Journal: Biochimica et biophysica acta 20090501

Title: Thymoquinone protects dopaminergic neurons against MPP+ and rotenone.

Journal: Phytotherapy research : PTR 20090501

Title: Inhibition of mitochondrial function induces an integrated stress response in oligodendroglia.

Journal: Neurobiology of disease 20090501

Title: Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090501

Title: Monitoring the in vivo redox state of plant mitochondria: effect of respiratory inhibitors, abiotic stress and assessment of recovery from oxidative challenge.

Journal: Biochimica et biophysica acta 20090501

Title: A highly reproducible rotenone model of Parkinson's disease.

Journal: Neurobiology of disease 20090501

Title: A2A adenosine receptor antagonists protect the striatum against rotenone-induced neurotoxicity.

Journal: Experimental neurology 20090501

Title: Modulation of connexin 43 in rotenone-induced model of Parkinson's disease.

Journal: Neuroscience 20090421

Title: Assembly of a chimeric respiratory chain from bovine heart submitochondrial particles and cytochrome bd terminal oxidase of Escherichia coli.

Journal: FEBS letters 20090417

Title: Protective effects of asiatic acid on rotenone- or H2O2-induced injury in SH-SY5Y cells.

Journal: Neurochemical research 20090401

Title: Toxicological assessment of chemicals using Caenorhabditis elegans and optical oxygen respirometry.

Journal: Environmental toxicology and chemistry 20090401

Title: Mitochondria-derived reactive oxygen species mediate heme oxygenase-1 expression in sheared endothelial cells.

Journal: The Journal of pharmacology and experimental therapeutics 20090401

Title: Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation.

Journal: Nature chemical biology 20090401

Title: Liposomal encapsulation of deguelin: evidence for enhanced antitumor activity in tobacco carcinogen-induced and oncogenic K-ras-induced lung tumorigenesis.

Journal: Cancer prevention research (Philadelphia, Pa.) 20090401

Title: Forensic studies of brain vulnerability and resistance: ischemia-induced dopamine and serotonin releases in the rat nucleus accumbens.

Journal: Legal medicine (Tokyo, Japan) 20090401

Title: Methylene blue provides behavioral and metabolic neuroprotection against optic neuropathy.

Journal: Neurotoxicity research 20090401

Title: Residues of rotenone, azadirachtin, pyrethrins and copper used to control Bactrocera oleae (Gmel.) in organic olives and oil.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090401

Title: Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species.

Journal: Biochemistry 20090310

Title: Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice.

Journal: Biochemical and biophysical research communications 20090306

Title: Proteasomal inhibition reduces parkin mRNA in PC12 and SH-SY5Y cells.

Journal: Parkinsonism & related disorders 20090301

Title: Inhibitory modulation of the mitochondrial permeability transition by minocycline.

Journal: Biochemical pharmacology 20090301

Title: Inhibitory vs. protective effects of N-acetyl-l-cysteine (NAC) on the electromechanical properties of the spontaneously beating atria of the frog (Rana ridibunda): an ex vivo study.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20090301

Title: Nicotinic receptor-mediated neuroprotection in neurodegenerative disease models.

Journal: Biological & pharmaceutical bulletin 20090301

Title: Rotenone reduces Mg2+-dependent block of NMDA currents in substantia nigra dopamine neurons.

Journal: Neurotoxicology 20090301

Title: Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways.

Journal: The Journal of biological chemistry 20090227

Title: Effects of lactate on beef heart mitochondrial oxygen consumption and muscle darkening.

Journal: Journal of agricultural and food chemistry 20090225

Title: Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes.

Journal: Toxicology letters 20090210

Title: Parkin protects dopaminergic neurons against microtubule-depolymerizing toxins by attenuating microtubule-associated protein kinase activation.

Journal: The Journal of biological chemistry 20090206

Title: Nicotinic receptor stimulation protects nigral dopaminergic neurons in rotenone-induced Parkinson's disease models.

Journal: Journal of neuroscience research 20090201

Title: Low dose rotenone treatment causes selective transcriptional activation of cell death related pathways in dopaminergic neurons in vivo.

Journal: Neurobiology of disease 20090201

Title: Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha.

Journal: Journal of neurochemistry 20090201

Title: Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3'-untranslated region: implications in neurodegenerative diseases.

Journal: The Journal of biological chemistry 20090116

Title: Oxidative and inflammatory pathways in Parkinson's disease.

Journal: Neurochemical research 20090101

Title: Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats.

Journal: Endocrinology 20090101

Title: Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function.

Journal: Molecular pharmacology 20090101

Title: Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells.

Journal: Molecular and cellular biochemistry 20090101

Title: DJ-1 knock-down in astrocytes impairs astrocyte-mediated neuroprotection against rotenone.

Journal: Neurobiology of disease 20090101

Title: Catalpol attenuates nitric oxide increase via ERK signaling pathways induced by rotenone in mesencephalic neurons.

Journal: Neurochemistry international 20090101

Title: Induction of Arabidopsis gdh2 gene expression during changes in redox state of the mitochondrial respiratory chain.

Journal: Biochemistry. Biokhimiia 20090101

Title: Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I.

Journal: The international journal of biochemistry & cell biology 20090101

Title: Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

Journal: PloS one 20090101

Title: Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease.

Journal: Journal of translational medicine 20090101

Title: Mitochondrial respiration is required for activation of ERK1/2 and caspase-3 in human eosinophils stimulated with hydrogen peroxide.

Journal: Journal of investigational allergology & clinical immunology 20090101

Title: Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders.

Journal: PloS one 20090101

Title: Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Stereotaxical infusion of rotenone: a reliable rodent model for Parkinson's disease.

Journal: PloS one 20090101

Title: [Grazing systems, rotenone and parasites control in crossbred calves: effect on live weight gain and on parasites burdens].

Journal: Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 20090101

Title: Effects of rotenone from derris crude extract on esterase enzyme mechanism in the beet armyworm, Spodoptera exiqua (Hubner).

Journal: Communications in agricultural and applied biological sciences 20090101

Title: The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit Bbeta2 antagonizes neuronal survival by promoting mitochondrial fission.

Journal: The Journal of biological chemistry 20081226

Title: Glycolytic oscillations in isolated rabbit ventricular myocytes.

Journal: The Journal of biological chemistry 20081226

Title: Neuroprotective effects of near-infrared light in an in vivo model of mitochondrial optic neuropathy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081210

Title: Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity.

Journal: Brain research 20081203

Title: Deguelin inhibits retinal neovascularization by down-regulation of HIF-1alpha in oxygen-induced retinopathy.

Journal: Journal of cellular and molecular medicine 20081201

Title: Comparison of glycolysis and oxidative phosphorylation as energy sources for mammalian sperm motility, using the combination of fluorescence imaging, laser tweezers, and real-time automated tracking and trapping.

Journal: Journal of cellular physiology 20081201

Title: Mechanism of the neuroprotective role of coenzyme Q10 with or without L-dopa in rotenone-induced parkinsonism.

Journal: Neuropharmacology 20081201

Title: Characterization of demethylation of methylmercury in cultured astrocytes.

Journal: Chemosphere 20081201

Title: Effect of magnesium ions on the activity of the cytosolic NADH/cytochrome c electron transport system.

Journal: The FEBS journal 20081201

Title: Unregulated mitochondrial GSK3beta activity results in NADH: ubiquinone oxidoreductase deficiency.

Journal: Neurotoxicity research 20081201

Title: Rotenone damages striatal organotypic slice culture.

Journal: Annals of the New York Academy of Sciences 20081201

Title: A novel derivative of the natural agent deguelin for cancer chemoprevention and therapy.

Journal: Cancer prevention research (Philadelphia, Pa.) 20081201

Title: Increased vulnerability to rotenone-induced neurotoxicity in ceruloplasmin-deficient mice.

Journal: Neuroscience letters 20081128

Title: Prostaglandin analogue misoprostol attenuates neurotoxin 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death in differentiated PC12 cells.

Journal: Brain research bulletin 20081125

Title: Altered NAD(P)H production in neonatal rat islets resistant to H2O2.

Journal: Life sciences 20081121

Title: Interaction of mitochondrial respiratory inhibitors and excitotoxins potentiates cell death in hippocampal slice cultures.

Journal: Journal of neuroscience research 20081115

Title: Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures.

Journal: Journal of neuroscience research 20081115

Title: Mitochondrial defects and dysfunction in calcium regulation in glaucomatous trabecular meshwork cells.

Journal: Investigative ophthalmology & visual science 20081101

Title: Complex I dysfunction redirects cellular and mitochondrial metabolism in Arabidopsis.

Journal: Plant physiology 20081101

Title: Mechanisms mediating the oxygen-induced vasoreactivity of the ductus arteriosus in the chicken embryo.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081101

Title: Mitochondria-derived reactive oxygen species mediate sympathoexcitation induced by angiotensin II in the rostral ventrolateral medulla.

Journal: Journal of hypertension 20081101

Title: Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts.

Journal: Annals of neurology 20081101

Title: [Cellular pathophysiology of Parkinson's disease].

Journal: Rinsho shinkeigaku = Clinical neurology 20081101

Title: The role of external and matrix pH in mitochondrial reactive oxygen species generation.

Journal: The Journal of biological chemistry 20081024

Title: NADH oxidation drives respiratory Na+ transport in mitochondria from Yarrowia lipolytica.

Journal: Archives of microbiology 20081001

Title: Mitochondrial complex I inhibitor rotenone inhibits and redistributes vesicular monoamine transporter 2 via nitration in human dopaminergic SH-SY5Y cells.

Journal: Molecular pharmacology 20081001

Title: Channels for water efflux and influx involved in volume regulation of murine spermatozoa.

Journal: Reproduction (Cambridge, England) 20081001

Title: Role of mitochondria in modulation of spontaneous Ca2+ waves in freshly dispersed interstitial cells of Cajal from the rabbit urethra.

Journal: The Journal of physiology 20081001

Title: Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils.

Journal: Journal of natural products 20081001

Title: Extranigral neurodegeneration in Parkinson's disease.

Journal: Annals of the New York Academy of Sciences 20081001

Title: Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20080930

Title: Overexpression of Kir2.3 in PC12 cells resists rotenone-induced neurotoxicity associated with PKC signaling pathway.

Journal: Biochemical and biophysical research communications 20080919

Title: Rotenone inhibits delayed rectifier K+ current via a protein kinase A-dependent mechanism.

Journal: Neuroreport 20080917

Title: Oxygen flux as an indicator of physiological stress in fathead minnow (Pimephales promelas) embryos: a real-time biomonitoring system of water quality.

Journal: Environmental science & technology 20080915

Title: Rotenone-induced PC12 cell toxicity is caused by oxidative stress resulting from altered dopamine metabolism.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080901

Title: Arterial baroreflex dysfunction fails to mimic Parkinson's disease in rats.

Journal: Journal of pharmacological sciences 20080901

Title: Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation.

Journal: Journal of cellular and molecular medicine 20080901

Title: Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death.

Journal: The Journal of biological chemistry 20080822

Title: Electrophysiology and pharmacology of striatal neuronal dysfunction induced by mitochondrial complex I inhibition.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080806

Title: Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults.

Journal: Free radical biology & medicine 20080801

Title: Rotenone-induced toxicity is mediated by Rho-GTPases in hippocampal neurons.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080801

Title: First evidence for a crosstalk between mitochondrial and NADPH oxidase-derived reactive oxygen species in nitroglycerin-triggered vascular dysfunction.

Journal: Antioxidants & redox signaling 20080801

Title: Identification of regulatory pathways controlling gene expression of stress-responsive mitochondrial proteins in Arabidopsis.

Journal: Plant physiology 20080801

Title: Involvement of mitochondrial alteration and reactive oxygen species generation in Taiwan cobra cardiotoxin-induced apoptotic death of human neuroblastoma SK-N-SH cells.

Journal: Toxicon : official journal of the International Society on Toxinology 20080801

Title: Modulation of SIRT1 expression in different neurodegenerative models and human pathologies.

Journal: Neuroscience 20080717

Title: Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury.

Journal: American journal of respiratory and critical care medicine 20080715

Title: Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells.

Journal: Neuroscience letters 20080711

Title: Decylubiquinol impedes mitochondrial respiratory chain complex I activity.

Journal: Molecular and cellular biochemistry 20080701

Title: Protective effect of the green tea component, L-theanine on environmental toxins-induced neuronal cell death.

Journal: Neurotoxicology 20080701

Title: GSK3beta and endoplasmic reticulum stress mediate rotenone-induced death of SK-N-MC neuroblastoma cells.

Journal: Biochemical pharmacology 20080701

Title: Deguelin inhibits human hepatocellular carcinoma by antiangiogenesis and apoptosis.

Journal: Oncology reports 20080701

Title: Essential roles of caspases and their upstream regulators in rotenone-induced apoptosis.

Journal: Biochemical and biophysical research communications 20080620

Title: Neuroprotective effects of memantine in a mouse model of retinal degeneration induced by rotenone.

Journal: Brain research 20080618

Title: Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents.

Journal: Bioorganic & medicinal chemistry 20080615

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Interactions between PBEF and oxidative stress proteins--a potential new mechanism underlying PBEF in the pathogenesis of acute lung injury.

Journal: FEBS letters 20080611

Title: Near-infrared light via light-emitting diode treatment is therapeutic against rotenone- and 1-methyl-4-phenylpyridinium ion-induced neurotoxicity.

Journal: Neuroscience 20080602

Title: Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease.

Journal: Journal of neurochemistry 20080601

Title: Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line.

Journal: American journal of physiology. Cell physiology 20080601

Title: L-Proline uptake in Crithidia deanei is influenced by its endosymbiont bacterium.

Journal: FEMS microbiology letters 20080601

Title: STIM1 regulates acidic Ca2+ store refilling by interaction with SERCA3 in human platelets.

Journal: Biochemical pharmacology 20080601

Title: Isoflavones and rotenoids from the leaves of Millettia brandisiana.

Journal: Chemical & pharmaceutical bulletin 20080601

Title: Enhancement radiosensitization of breast cancer cells by deguelin.

Journal: Cancer biotherapy & radiopharmaceuticals 20080601

Title: Synthesis and biological evaluation of pyridazinone analogues as potential cardiac positron emission tomography tracers.

Journal: Journal of medicinal chemistry 20080522

Title: Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080507

Title: Dopamine selectively sensitizes dopaminergic neurons to rotenone-induced apoptosis.

Journal: Neurochemical research 20080501

Title: Degradation of caspase-activated DNase by the ubiquitin-proteasome system.

Journal: Biochimica et biophysica acta 20080501

Title: Hymenolepis diminuta: mitochondrial transhydrogenase as an additional site for anaerobic phosphorylation.

Journal: Experimental parasitology 20080501

Title: Role and regulation of ferritin H in rotenone-mediated mitochondrial oxidative stress.

Journal: Free radical biology & medicine 20080501

Title: Nitric oxide degradation by potato tuber mitochondria: evidence for the involvement of external NAD(P)H dehydrogenases.

Journal: Biochimica et biophysica acta 20080501

Title: Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection.

Journal: Neurotoxicology 20080501

Title: Inhibition of carrier-mediated uptake of epirubicin reduces cytotoxicity in primary culture of rat hepatocytes.

Journal: Journal of applied toxicology : JAT 20080401

Title: Hypoxanthine uptake and release by equilibrative nucleoside transporter 2 (ENT2) of rat microvascular endothelial cells.

Journal: Microvascular research 20080401

Title: TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401

Title: Mitochondrial complex I defect induces ROS release and degeneration in trabecular meshwork cells of POAG patients: protection by antioxidants.

Journal: Investigative ophthalmology & visual science 20080401

Title: Interplay between bax, reactive oxygen species production, and cardiolipin oxidation during apoptosis.

Journal: Biochemical and biophysical research communications 20080328

Title: Behavioral alterations in rotenone model of Parkinson's disease: attenuation by co-treatment of centrophenoxine.

Journal: Brain research 20080327

Title: Mechanistic investigations of low dose exposures to the genotoxic compounds bisphenol-A and rotenone.

Journal: Mutation research 20080312

Title: Effects of the extract of Anemopaegma mirandum (Catuaba) on Rotenone-induced apoptosis in human neuroblastomas SH-SY5Y cells.

Journal: Brain research 20080310

Title: D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways.

Journal: FEBS letters 20080305

Title: Sequential and concerted gene expression changes in a chronic in vitro model of parkinsonism.

Journal: Neuroscience 20080303

Title: ATP depletion inhibits Ca2+ release, influx and extrusion in pancreatic acinar cells but not pathological Ca2+ responses induced by bile.

Journal: Pflugers Archiv : European journal of physiology 20080301

Title: Protocatechuic acid inhibits apoptosis by mitochondrial dysfunction in rotenone-induced PC12 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080301

Title: Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats.

Journal: Journal of pineal research 20080301

Title: Investigating convergent actions of genes linked to familial Parkinson's disease.

Journal: Neuro-degenerative diseases 20080301

Title: Shear fluid-induced Ca2+ release and the role of mitochondria in rat cardiac myocytes.

Journal: Annals of the New York Academy of Sciences 20080301

Title: Fibroblasts from naked mole-rats are resistant to multiple forms of cell injury, but sensitive to peroxide, ultraviolet light, and endoplasmic reticulum stress.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20080301

Title: The role of dopamine transporter in selective toxicity of manganese and rotenone.

Journal: Toxicology 20080227

Title: Dopaminergic neurons are preferentially sensitive to long-term rotenone toxicity in primary cell culture.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080201

Title: Antiangiogenic effect of deguelin on choroidal neovascularization.

Journal: The Journal of pharmacology and experimental therapeutics 20080201

Title: Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria.

Journal: American journal of physiology. Cell physiology 20080201

Title: Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages.

Journal: Biochimica et biophysica acta 20080201

Title: Protection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids.

Journal: Investigative ophthalmology & visual science 20080201

Title: Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography.

Journal: Journal of chromatography. A 20080118

Title: ATP depletion inhibits the endocytosis of ClC-2.

Journal: Journal of cellular physiology 20080101

Title: Rotenoid derivatives and other constituents of the twigs of Millettia duchesnei.

Journal: Phytochemistry 20080101

Title: Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.

Journal: International journal of cancer 20080101

Title: Alterations of striatal glutamate transmission in rotenone-treated mice: MRI/MRS in vivo studies.

Journal: Experimental neurology 20080101

Title: The exploration of rotenone as a toxin for inducing Parkinson's disease in rats, for application in BBB transport and PK-PD experiments.

Journal: Journal of pharmacological and toxicological methods 20080101

Title: Deguelin represses both the expression of nucleophosmin and some nucleoporins: Nup88 and Nup214 in Jurkat cells.

Journal: Biological & pharmaceutical bulletin 20080101

Title: Protection by the NDI1 gene against neurodegeneration in a rotenone rat model of Parkinson's disease.

Journal: PloS one 20080101

Title: Oxidative stress caused by blocking of mitochondrial complex I H(+) pumping as a link in aging/disease vicious cycle.

Journal: The international journal of biochemistry & cell biology 20080101

Title: The influence of visible light exposure on cultured RGC-5 cells.

Journal: Molecular vision 20080101

Title: Studies on cellular resilience and adaptation following acute and repetitive exposure to ozone in cultured human epithelial (HeLa) cells.

Journal: Redox report : communications in free radical research 20080101

Title: Isoflavonoid glycosides and rotenoids from Pongamia pinnata leaves.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101

Title: Malate metabolism in Hoya carnosa mitochondria and its role in photosynthesis during CAM phase III.

Journal: Journal of experimental botany 20080101

Title: Altered threshold of the mitochondrial permeability transition pore in Ullrich congenital muscular dystrophy.

Journal: Biochimica et biophysica acta 20080101

Title: Transgenic mice expressing cyan fluorescent protein as a reporter strain to detect the effects of rotenone toxicity on retinal ganglion cells.

Journal: Journal of toxicology and environmental health. Part A 20080101

Title: CD133 is a marker of bioenergetic stress in human glioma.

Journal: PloS one 20080101

Title: Pesticide/environmental exposures and Parkinson's disease in East Texas.

Journal: Journal of agromedicine 20080101

Title: Mitochondrial production of reactive oxygen species: role of complex I and quinone analogues.

Journal: BioFactors (Oxford, England) 20080101

Title: NADPH-dependent coenzyme Q reductase is the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells.

Journal: BioFactors (Oxford, England) 20080101

Title: Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells.

Journal: Molecular neurodegeneration 20080101

Title: [Two molecular motility systems of the frog olfactory cilia].

Journal: Biofizika 20080101

Title: Flow cytometric quantification of glucose-stimulated beta-cell metabolic flux can reveal impaired islet functional potency.

Journal: Cell transplantation 20080101

Title: Reversible dissociation of flavin mononucleotide from the mammalian membrane-bound NADH: ubiquinone oxidoreductase (complex I).

Journal: FEBS letters 20071222

Title: Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin.

Journal: Cancer research 20071215

Title: Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20071201

Title: Differential effects of classical and atypical antipsychotic drugs on rotenone-induced neurotoxicity in PC12 cells.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20071201

Title: HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes.

Journal: American journal of physiology. Endocrinology and metabolism 20071201

Title: Chondroitin sulfate protects SH-SY5Y cells from oxidative stress by inducing heme oxygenase-1 via phosphatidylinositol 3-kinase/Akt.

Journal: The Journal of pharmacology and experimental therapeutics 20071201

Title: Phytanic acid impairs mitochondrial respiration through protonophoric action.

Journal: Cellular and molecular life sciences : CMLS 20071201

Title: Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species.

Journal: Journal of cell science 20071201

Title: Effect of intermittent normobaric hypoxia on kinetic properties of mitochondrial enzymes.

Journal: Bulletin of experimental biology and medicine 20071201

Title: Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson's disease: a dynamic model.

Journal: Neuroscience 20071123

Title: Rotenone enhances N-methyl-D-aspartate currents by activating a tyrosine kinase in rat dopamine neurons.

Journal: Neuroreport 20071119

Title: Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo.

Journal: Biology of reproduction 20071101

Title: Reactive oxygen species (ROS) mediate the effects of leucine on translation regulation and type I collagen production in hepatic stellate cells.

Journal: Biochimica et biophysica acta 20071101

Title: Mitochondrial complex I inhibitor rotenone-elicited dopamine redistribution from vesicles to cytosol in human dopaminergic SH-SY5Y cells.

Journal: The Journal of pharmacology and experimental therapeutics 20071101

Title: Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats.

Journal: Experimental neurology 20071101

Title: Epigallocatechin gallate (EGCG) potentiates the cytotoxicity of rotenone in neuroblastoma SH-SY5Y cells.

Journal: Brain research 20071024

Title: Involvement of Candida albicans pyruvate dehydrogenase complex protein X (Pdx1) in filamentation.

Journal: Fungal genetics and biology : FG & B 20071001

Title: Rotenone selectively kills serotonergic neurons through a microtubule-dependent mechanism.

Journal: Journal of neurochemistry 20071001

Title: Zaprinast inhibits hydrogen peroxide-induced lysosomal destabilization and cell death in astrocytes.

Journal: European journal of pharmacology 20071001

Title: Mitochondrial DNA deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins.

Journal: Aging cell 20071001

Title: Memantine reduces neuronal dysfunctions triggered by in vitro ischemia and 3-nitropropionic acid.

Journal: Experimental neurology 20071001

Title: Bioenergetic and oxidative effects of free 3-nitrotyrosine in culture: selective vulnerability of dopaminergic neurons and increased sensitivity of non-dopaminergic neurons to dopamine oxidation.

Journal: Journal of neurochemistry 20071001

Title: Redox-dependent change of nucleotide affinity to the active site of the mammalian complex I.

Journal: Biochemistry 20070925

Title: Synthesis and biological evaluation of the mitochondrial complex 1 inhibitor 2-[4-(4-fluorobutyl)benzylsulfanyl]-3-methylchromene-4-one as a potential cardiac positron emission tomography tracer.

Journal: Journal of medicinal chemistry 20070906

Title: Role of AMP-activated protein kinase in exercise capacity, whole body glucose homeostasis, and glucose transport in skeletal muscle -insight from analysis of a transgenic mouse model-.

Journal: Diabetes research and clinical practice 20070901

Title: Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins.

Journal: Journal of neurochemistry 20070901

Title: Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin.

Journal: American journal of physiology. Renal physiology 20070901

Title: Mitochondrial and cytosolic thiol redox state are not detectably altered in isolated human NADH:ubiquinone oxidoreductase deficiency.

Journal: Biochimica et biophysica acta 20070901

Title: Modulation of TASK-like background potassium channels in rat arterial chemoreceptor cells by intracellular ATP and other nucleotides.

Journal: The Journal of physiology 20070901

Title: Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding.

Journal: The FEBS journal 20070901

Title: Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening.

Journal: Chemical research in toxicology 20070901

Title: Endoplasmic reticulum is a key organella in bradykinin-triggered ATP release from cultured smooth muscle cells.

Journal: Journal of pharmacological sciences 20070901

Title: Photodegradation of rotenone in soils under environmental conditions.

Journal: Journal of agricultural and food chemistry 20070822

Title: Mechanism of cell death caused by complex I defects in a rat dopaminergic cell line.

Journal: The Journal of biological chemistry 20070817

Title: Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070808

Title: Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20070801

Title: Deguelin inhibits expression of IkappaBalpha protein and induces apoptosis of B-CLL cells in vitro.

Journal: Leukemia 20070801

Title: Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa}B via c-SRC and oxidant-dependent cell death.

Journal: Cancer research 20070801

Title: Unique responses to mitochondrial complex I inhibition in tuberoinfundibular dopamine neurons may impart resistance to toxic insult.

Journal: Neuroscience 20070713

Title: Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070704

Title: Regulation of transient receptor potential melastatin 7 (TRPM7) currents by mitochondria.

Journal: Molecules and cells 20070630

Title: 'Rejuvenation' protects neurons in mouse models of Parkinson's disease.

Journal: Nature 20070628

Title: Rotenone potentiates NMDA currents in substantia nigra dopamine neurons.

Journal: Neuroscience letters 20070627

Title: Astrocytes protect MN9D neuronal cells against rotenone-induced oxidative stress by a glutathione-dependent mechanism.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20070625

Title: Structural basis for depletion of heat shock protein 90 client proteins by deguelin.

Journal: Journal of the National Cancer Institute 20070620

Title: Rotenone-induced neurotoxicity of THP-1 cells requires production of reactive oxygen species and activation of phosphatidylinositol 3-kinase.

Journal: Brain research 20070611

Title: Mitochondrial OXPHOS functions in R1H rhabdomyosarcoma and skeletal muscles of the rat.

Journal: Neurochemical research 20070601

Title: Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone.

Journal: Journal of neurochemistry 20070601

Title: Complex I binding by a virally encoded RNA regulates mitochondria-induced cell death.

Journal: Science (New York, N.Y.) 20070601

Title: [Rotenoids from Derris trifoliata].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070601

Title: The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of Lewis rats.

Journal: Neuroscience 20070511

Title: [Proteolytic stress induced by environmental toxins in dopaminergic neurons: an experimental study].

Journal: Zhonghua yi xue za zhi 20070508

Title: Effects of temperature on pacemaker potentials in the mouse small intestine.

Journal: Pflugers Archiv : European journal of physiology 20070501

Title: Exercise training decreases rat heart mitochondria free radical generation but does not prevent Ca2+-induced dysfunction.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070501

Title: Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070501

Title: Endogenous production of reactive oxygen species is required for stimulation of human articular chondrocyte matrix metalloproteinase production by fibronectin fragments.

Journal: Free radical biology & medicine 20070501

Title: Effect of the inhibitory neurotransmitter glycine on slow destructive processes in brain cortex slices under anoxic conditions.

Journal: Biochemistry. Biokhimiia 20070501

Title: Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons.

Journal: Neuroscience 20070425

Title: ROS generation in endothelial hypoxia and reoxygenation stimulates MAP kinase signaling and kinase-dependent neutrophil recruitment.

Journal: Free radical biology & medicine 20070415

Title: Stereoselective syntheses of the 2-Isopropenyl-2,3-dihydrobenzofuran nucleus: potential chiral building blocks for the syntheses of tremetone, hydroxytremetone, and rotenone.

Journal: The Journal of organic chemistry 20070413

Title: Melatonin protects against rotenone-induced oxidative stress in a hemiparkinsonian rat model.

Journal: Journal of pineal research 20070401

Title: Mitochondrial delivery is essential for synaptic potentiation.

Journal: The Biological bulletin 20070401

Title: Behavioural and neural deficits induced by rotenone in the pond snail Lymnaea stagnalis. A possible model for Parkinson's disease in an invertebrate.

Journal: The European journal of neuroscience 20070401

Title: Anti-cancer effects of deguelin on human leukemia K562 and K562/ADM cells In Vitro.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070401

Title: Interleukin-1beta mediates sleep alteration in rats with rotenone-induced parkinsonism.

Journal: Sleep 20070401

Title: Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death.

Journal: Brain research bulletin 20070330

Title: A genomic screen for activators of the antioxidant response element.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20070320

Title: AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro.

Journal: The Journal of biological chemistry 20070309

Title: Rotenone and MPP+ preferentially redistribute apoptosis-inducing factor in apoptotic dopamine neurons.

Journal: Neuroreport 20070305

Title: A rotenone-sensitive site and H2O2 are key components of hypoxia-sensing in neonatal rat adrenomedullary chromaffin cells.

Journal: Neuroscience 20070302

Title: Neuroprotective effects of ginsenoside-Rg1 in primary nigral neurons against rotenone toxicity.

Journal: Neuropharmacology 20070301

Title: Pharmacological and physiological stimuli do not promote Ca(2+)-sensitive K+ channel activity in isolated heart mitochondria.

Journal: Cardiovascular research 20070301

Title: RNAi knockdown of caspase-activated DNase inhibits rotenone-induced DNA fragmentation in HeLa cells.

Journal: Neurochemistry international 20070301

Title: Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease.

Journal: Journal of neurochemistry 20070301

Title: Alpha-synuclein and tyrosine hydroxylase expression in acute rotenone toxicity.

Journal: International journal of molecular medicine 20070301

Title: [Effect of deguelin on proliferation and apoptosis of lymphoma Daudi cells and its mechanism].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070301

Title: Chronic rotenone treatment induces behavioral effects but no pathological signs of parkinsonism in mice.

Journal: Journal of neuroscience research 20070215

Title: Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.

Journal: Cancer chemotherapy and pharmacology 20070201

Title: The Akt inhibitor deguelin, is an angiopreventive agent also acting on the NF-kappaB pathway.

Journal: Carcinogenesis 20070201

Title: Bidirectional Ca2+ coupling of mitochondria with the endoplasmic reticulum and regulation of multimodal Ca2+ entries in rat brown adipocytes.

Journal: American journal of physiology. Cell physiology 20070201

Title: Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease.

Journal: Experimental neurology 20070201

Title: ATP depletion does not account for apoptosis induced by inhibition of mitochondrial electron transport chain in human dopaminergic cells.

Journal: Neuropharmacology 20070201

Title: Standardized Hypericum perforatum reduces oxidative stress and increases gene expression of antioxidant enzymes on rotenone-exposed rats.

Journal: Neuropharmacology 20070201

Title: RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport.

Journal: Journal of neuroscience research 20070201

Title: Skin-derived fibroblasts from long-lived species are resistant to some, but not all, lethal stresses and to the mitochondrial inhibitor rotenone.

Journal: Aging cell 20070201

Title: Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa.

Journal: Bioorganic & medicinal chemistry 20070201

Title: [Effect of deguelin on expression of nup98 in K562 cells].

Journal: Zhongguo shi yan xue ye xue za zhi 20070201

Title: [Deguelin regulates cell cycle and nuclear pore complex protein Nup98 and Nup88 in U937 cells in vitro].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20070201

Title: Moderate dependence of ROS formation on DeltaPsim in isolated brain mitochondria supported by NADH-linked substrates.

Journal: Neurochemical research 20070101

Title: Divergent mechanisms of paraquat, MPP+, and rotenone toxicity: oxidation of thioredoxin and caspase-3 activation.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070101

Title: Down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cells.

Journal: Molecular pharmacology 20070101

Title: Mitochondrial damage modulates alternative splicing in neuronal cells: implications for neurodegeneration.

Journal: Journal of neurochemistry 20070101

Title: Mitochondrial toxins and neurodegenerative diseases.

Journal: Frontiers in bioscience : a journal and virtual library 20070101

Title: Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome.

Journal: Frontiers in bioscience : a journal and virtual library 20070101

Title: Effect of tributyltin (TBT) on ATP levels in human natural killer (NK) cells: relationship to TBT-induced decreases in NK function.

Journal: Journal of applied toxicology : JAT 20070101

Title: Quantification of basal and stimulated ROS levels as predictors of islet potency and function.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101

Title: CHOP (C/EBP homologous protein) and ASNS (asparagine synthetase) induction in cybrid cells harboring MELAS and NARP mitochondrial DNA mutations.

Journal: Mitochondrion 20070101

Title: Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.

Journal: Mitochondrion 20070101

Title: [Hepatocyte mitochondrion respiratory chain in rats with experimental toxic hepatitis].

Journal: Tsitologiia 20070101

Title: Is Parkinson's disease an autoimmune disorder of endogenous vasoactive neuropeptides?

Journal: Medical hypotheses 20070101

Title: The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation.

Journal: International journal of biological sciences 20070101

Title: Identification of novel proteins affected by rotenone in mitochondria of dopaminergic cells.

Journal: BMC neuroscience 20070101

Title: Evaluation of the impact on entomocoenosis of active agents allowed in organic olive farming against Bactrocera oleae (Gmelin, 1790).

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20070101

Title: [Wheat root cells functioning under inhibition of I and II complexes of mitochondrial respiratory chain].

Journal: Tsitologiia 20070101

Title: [The experimental models of Parkinson's disease in animals].

Journal: Uspekhi fiziologicheskikh nauk 20070101

Title: Isolation and functional analysis of mitochondria from the nematode Caenorhabditis elegans.

Journal: Methods in molecular biology (Clifton, N.J.) 20070101

Title: Mitochondrial ROS-PKCepsilon signaling axis is uniquely involved in hypoxic increase in [Ca2+]i in pulmonary artery smooth muscle cells.

Journal: Biochemical and biophysical research communications 20061222

Title: Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells.

Journal: The Journal of biological chemistry 20061208

Title: Pyruvate and oxaloacetate limit zinc-induced oxidative HT-22 neuronal cell injury.

Journal: Neurotoxicology 20061201

Title: NR2B-containing NMDA receptors promote the neurotoxic effects of 3-nitropropionic acid but not of rotenone in the striatum.

Journal: Experimental neurology 20061201

Title: Significant increase of glycolytic flux in Torulopsis glabrata by inhibition of oxidative phosphorylation.

Journal: FEMS yeast research 20061201

Title: Microtubule: a common target for parkin and Parkinson's disease toxins.

Journal: The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20061201

Title: Transient and partial mitochondrial inhibition for the treatment of postresuscitation injury: getting it just right.

Journal: Critical care medicine 20061201

Title: Accumulation of lipophilic dications by mitochondria and cells.

Journal: The Biochemical journal 20061115

Title: Carnosol, a component of rosemary (Rosmarinus officinalis L.) protects nigral dopaminergic neuronal cells.

Journal: Neuroreport 20061106

Title: D-beta-hydroxybutyrate protects dopaminergic SH-SY5Y cells in a rotenone model of Parkinson's disease.

Journal: Journal of neuroscience research 20061101

Title: Partial mitochondrial complex I inhibition induces oxidative damage and perturbs glutamate transport in primary retinal cultures. Relevance to Leber Hereditary Optic Neuropathy (LHON).

Journal: Neurobiology of disease 20061101

Title: Correlated resistance to glucose deprivation and cytotoxic agents in fibroblast cell lines from long-lived pituitary dwarf mice.

Journal: Mechanisms of ageing and development 20061101

Title: Structures of new flavonoids, erycibenins D, E, and F, and NO production inhibitors from Erycibe expansa originating in Thailand.

Journal: Chemical & pharmaceutical bulletin 20061101

Title: [Overexpression of alpha-synuclein in SH-SY5Y cells partially protected against oxidative stress induced by rotenone].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20061025

Title: Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20061015

Title: Mitochondrial activity is modulated by TNFalpha and IL-1beta in normal human chondrocyte cells.

Journal: Osteoarthritis and cartilage 20061001

Title: Iptakalim modulates ATP-sensitive K(+) channels in dopamine neurons from rat substantia nigra pars compacta.

Journal: The Journal of pharmacology and experimental therapeutics 20061001

Title: Geographic isolates of atypical Parkinsonism and tauopathy in the tropics: possible synergy of neurotoxins.

Journal: Movement disorders : official journal of the Movement Disorder Society 20061001

Title: Differential effect of nerve growth factor on dopaminergic neurotoxin-induced apoptosis.

Journal: Journal of neurochemistry 20061001

Title: Neurotrophic factors stabilize microtubules and protect against rotenone toxicity on dopaminergic neurons.

Journal: The Journal of biological chemistry 20060929

Title: RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927

Title: Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration.

Journal: Neurochemistry international 20060901

Title: Potentiating effect of the ATP-sensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo.

Journal: Neurotoxicology 20060901

Title: Extraction of rotenone from Derris elliptica and Derris malaccensis by pressurized liquid extraction compared with maceration.

Journal: Journal of chromatography. A 20060901

Title: Neurodegeneration produced by rotenone in the mouse retina: a potential model to investigate environmental pesticide contributions to neurodegenerative diseases.

Journal: Journal of toxicology and environmental health. Part A 20060901

Title: alpha-Synuclein redistributed and aggregated in rotenone-induced Parkinson's disease rats.

Journal: Neuroscience bulletin 20060901

Title: Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

Journal: The EMBO journal 20060823

Title: Copper-induced stimulation of extracellular signal-regulated kinase in trout hepatocytes: the role of reactive oxygen species, Ca2+, and cell energetics and the impact of extracellular signal-regulated kinase signaling on apoptosis and necrosis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060801

Title: Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801

Title: Mitochondrial disease activates transcripts of the unfolded protein response and cell cycle and inhibits vesicular secretion and oligodendrocyte-specific transcripts.

Journal: Mitochondrion 20060801

Title: Albumin-bound fatty acids induce mitochondrial oxidant stress and impair antioxidant responses in proximal tubular cells.

Journal: Kidney international 20060801

Title: Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROS.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20060720

Title: Electron transport complex I is required for CD8+ T cell function.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060715

Title: p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.

Journal: Brain research 20060712

Title: Chromatographic analysis of dopamine metabolism in a Parkinsonian model.

Journal: Journal of chromatography. A 20060707

Title: L-deprenyl protects against rotenone-induced, oxidative stress-mediated dopaminergic neurodegeneration in rats.

Journal: Neurochemistry international 20060701

Title: Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease.

Journal: Molecular & cellular proteomics : MCP 20060701

Title: Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na+/K+ ATPase.

Journal: Neurobiology of disease 20060701

Title: Benzothiadiazole inhibits mitochondrial NADH:ubiquinone oxidoreductase in tobacco.

Journal: Journal of plant physiology 20060701

Title: Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing.

Journal: Diabetes 20060701

Title: Monocyte-mediated rotenone neurotoxicity towards human neuroblastoma SH-SY5Y: role of mitogen-activated protein kinases.

Journal: Biological & pharmaceutical bulletin 20060701

Title: Stability of membrane potential in heart mitochondria: single mitochondrion imaging.

Journal: Biochemical and biophysical research communications 20060616

Title: Cytoprotection by lithium and valproate varies between cell types and cellular stresses.

Journal: European journal of pharmacology 20060606

Title: Increased sensitivity to MPTP in human alpha-synuclein A30P transgenic mice.

Journal: Neurobiology of aging 20060601

Title: Antioxidant and 15-lipoxygenase inhibitory activity of rotenoids, isoflavones and phenolic glycosides from Sarcolobus globosus.

Journal: Fitoterapia 20060601

Title: Rats with unilateral median forebrain bundle, but not striatal or nigral, lesions by the neurotoxins MPP+ or rotenone display differential sensitivity to amphetamine and apomorphine.

Journal: Pharmacology, biochemistry, and behavior 20060601

Title: In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease.

Journal: The Journal of biological chemistry 20060519

Title: Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage.

Journal: Neuroscience letters 20060515

Title: Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells.

Journal: The Journal of biological chemistry 20060505

Title: Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP.

Journal: American journal of physiology. Renal physiology 20060501

Title: Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system.

Journal: Neurobiology of disease 20060501

Title: Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with aging.

Journal: Parkinsonism & related disorders 20060501

Title: Definitive evidence for the nonmitochondrial production of superoxide anion by human spermatozoa.

Journal: The Journal of clinical endocrinology and metabolism 20060501

Title: Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline.

Journal: Journal of neurochemistry 20060501

Title: Neurodegeneration induced by complex I inhibition in a cellular model of familial amyotrophic lateral sclerosis.

Journal: Brain research bulletin 20060428

Title: Basic fibroblast growth factor protects against rotenone-induced dopaminergic cell death through activation of extracellular signal-regulated kinases 1/2 and phosphatidylinositol-3 kinase pathways.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060426

Title: Activation of group III metabotropic glutamate receptors attenuates rotenone toxicity on dopaminergic neurons through a microtubule-dependent mechanism.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060419

Title: Metallothionein isoform 2A expression is inducible and protects against ROS-mediated cell death in rotenone-treated HeLa cells.

Journal: The Biochemical journal 20060415

Title: Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.

Journal: The Journal of biological chemistry 20060414

Title: Early induction of calpains in rotenone-mediated neuronal apoptosis.

Journal: Neuroscience letters 20060401

Title: Deguelin inhibits expression of IkappaBalpha protein in Raji and U937 cells.

Journal: Acta pharmacologica Sinica 20060401

Title: Not only insulin stimulates mitochondriogenesis in muscle cells, but mitochondria are also essential for insulin-mediated myogenesis.

Journal: Cell proliferation 20060401

Title: Electron transport pathways for the oxidation of endogenous substrate(s) in Acidithiobacillus ferrooxidans.

Journal: Canadian journal of microbiology 20060401

Title: Inhibition of specific electron transport pathways leads to oxidative stress and decreased Candida albicans proliferation.

Journal: Journal of bioenergetics and biomembranes 20060401

Title: Synergism of rotenone by piperonyl butoxide in Haemonchus contortus and Trichostrongylus colubriformis in vitro: potential for drug-synergism through inhibition of nematode oxidative detoxification pathways.

Journal: Veterinary parasitology 20060331

Title: Rotenone-like action of the branched-chain phytanic acid induces oxidative stress in mitochondria.

Journal: The Journal of biological chemistry 20060317

Title: Depletion of cardiolipin and cytochrome c during ischemia increases hydrogen peroxide production from the electron transport chain.

Journal: Free radical biology & medicine 20060315

Title: Tetrahydrobiopterin causes mitochondrial dysfunction in dopaminergic cells: implications for Parkinson's disease.

Journal: Neurochemistry international 20060301

Title: Mitochondrial Ca2+ flux is a critical determinant of the Ca2+ dependence of mast cell degranulation.

Journal: Journal of leukocyte biology 20060301

Title: Mitochondrial electron transport in models of neuropathic and inflammatory pain.

Journal: Pain 20060301

Title: Comparison of larvicidal, adulticidal and acaricidal activity of two geometrical butylidenephthalide isomers.

Journal: Biological & pharmaceutical bulletin 20060301

Title: The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells.

Journal: Neuroscience letters 20060213

Title: Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats.

Journal: The international journal of neuropsychopharmacology 20060201

Title: A delivery strategy for rotenone microspheres in an animal model of Parkinson's disease.

Journal: Biomaterials 20060201

Title: Glatiramer acetate induces pro-apoptotic mechanisms involving Bcl-2, Bax and Cyt-c in peripheral lymphocytes from multiple sclerosis patients.

Journal: Journal of neurology 20060201

Title: Mitochondrial production of oxidants is necessary for physiological calcium oscillations.

Journal: Journal of cellular physiology 20060201

Title: Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060201

Title: The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin.

Journal: Journal of bioenergetics and biomembranes 20060201

Title: Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model of the blood-brain barrier.

Journal: Neurotoxicology 20060101

Title: Mode of mitochondrial Ca2+ clearance and its influence on secretory responses in stimulated chromaffin cells.

Journal: Cell calcium 20060101

Title: Botanical insecticides, deterrents, and repellents in modern agriculture and an increasingly regulated world.

Journal: Annual review of entomology 20060101

Title: Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20060101

Title: A dip in the chlorophyll fluorescence induction at 0.2-2 s in Trebouxia-possessing lichens reflects a fast reoxidation of photosystem I. A comparison with higher plants.

Journal: Biochimica et biophysica acta 20060101

Title: Rotenone produces opposite effects upon mouse striatal dopamine function as a result of environmental temperature.

Journal: Neurotoxicity research 20060101

Title: Methylene blue prevents neurodegeneration caused by rotenone in the retina.

Journal: Neurotoxicity research 20060101

Title: S-nitrosothiol inhibition of mitochondrial complex I causes a reversible increase in mitochondrial hydrogen peroxide production.

Journal: Biochimica et biophysica acta 20060101

Title: Production of reactive oxygen species in mitochondria of HeLa cells under oxidative stress.

Journal: Biochimica et biophysica acta 20060101

Title: Generation of superoxide by the mitochondrial Complex I.

Journal: Biochimica et biophysica acta 20060101

Title: Neural repair strategies for Parkinson's disease: insights from primate models.

Journal: Cell transplantation 20060101

Title: Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression.

Journal: Molecular neurodegeneration 20060101

Title: The rotenone model of parkinsonism--the five years inspection.

Journal: Journal of neural transmission. Supplementum 20060101

Title: Controversies on new animal models of Parkinson's disease pro and con: the rotenone model of Parkinson's disease (PD).

Journal: Journal of neural transmission. Supplementum 20060101

Title: [Role of mitochondria in reglulation of endothelial cell hyperpolarization to acetylcholine].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101

Title: Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.

Journal: The Journal of biological chemistry 20051230

Title: Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication.

Journal: The Journal of biological chemistry 20051223

Title: Valproic acid-mediated Hsp70 induction and anti-apoptotic neuroprotection in SH-SY5Y cells.

Journal: FEBS letters 20051219

Title: Effect of fraxetin on antioxidant defense and stress proteins in human neuroblastoma cell model of rotenone neurotoxicity. Comparative study with myricetin and N-acetylcysteine.

Journal: Toxicology and applied pharmacology 20051215

Title: Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function.

Journal: Human molecular genetics 20051215

Title: Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y.

Journal: Biochemical and biophysical research communications 20051202

Title: Dopaminergic neurotoxins require excitotoxic stimulation in organotypic cultures.

Journal: Neurobiology of disease 20051201

Title: Rotenone and CCCP inhibit tyrosine hydroxylation in rat striatal tissue slices.

Journal: Toxicology 20051201

Title: Efficacy of deguelin and silibinin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.

Journal: Neoplasia (New York, N.Y.) 20051201

Title: Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress.

Journal: The Journal of biological chemistry 20051125

Title: AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle.

Journal: The Journal of biological chemistry 20051125

Title: Deguelin as a chemopreventive agent in mouse lung tumorigenesis induced by tobacco smoke carcinogens.

Journal: Journal of the National Cancer Institute 20051116

Title: Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis.

Journal: Journal of the National Cancer Institute 20051116

Title: Fast and versatile multiresidue method for the analysis of botanical insecticides on fruits and vegetables by HPLC/DAD/MS.

Journal: Journal of agricultural and food chemistry 20051102

Title: Paraquat neurotoxicity is distinct from that of MPTP and rotenone.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20051101

Title: The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.

Journal: Journal of neurochemistry 20051101

Title: Morphine modulation of the ubiquitin-proteasome complex is neuroprotective.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20051101

Title: Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026

Title: Novel inhibitors of the mitochondrial respiratory chain: oximes and pyrrolines isolated from Penicillium brevicompactum and synthetic analogues.

Journal: Journal of agricultural and food chemistry 20051019

Title: Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin.

Journal: The Journal of biological chemistry 20051014

Title: Death-associated protein kinase as a sensor of mitochondrial membrane potential: role of lysosome in mitochondrial toxin-induced cell death.

Journal: The Journal of biological chemistry 20051014

Title: Selective vulnerability of dopaminergic neurons to microtubule depolymerization.

Journal: The Journal of biological chemistry 20051007

Title: Oxidative phosphorylation and the tricarboxylic acid cycle are essential for normal development of mouse ovarian follicles.

Journal: Human reproduction (Oxford, England) 20051001

Title: Oxygen-sensing pathway for SK channels in the ovine adrenal medulla.

Journal: Clinical and experimental pharmacology & physiology 20051001

Title: Deguelin regulates nuclear pore complex proteins Nup98 and Nup88 in U937 cells in vitro.

Journal: Acta pharmacologica Sinica 20051001

Title: Induction of apoptosis-like mitochondrial impairment triggers antioxidant and Bcl-2-dependent keratinocyte differentiation.

Journal: The Journal of investigative dermatology 20051001

Title: Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001

Title: Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease.

Journal: Current biology : CB 20050906

Title: Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin.

Journal: The Journal of biological chemistry 20050902

Title: Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells.

Journal: Cardiovascular research 20050901

Title: Fraxetin prevents rotenone-induced apoptosis by induction of endogenous glutathione in human neuroblastoma cells.

Journal: Neuroscience research 20050901

Title: Mitochondrial dysfunction in choline deficiency-induced apoptosis in cultured rat hepatocytes.

Journal: Free radical biology & medicine 20050901

Title: Early environmental origins of neurodegenerative disease in later life.

Journal: Environmental health perspectives 20050901

Title: Depressant effect of mitochondrial respiratory complex inhibitors on proteasome inhibitor-induced mitochondrial dysfunction and cell death in PC12 cells.

Journal: Neurochemical research 20050901

Title: Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks.

Journal: Circulation research 20050819

Title: Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells.

Journal: American journal of physiology. Heart and circulatory physiology 20050801

Title: Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells.

Journal: Immunology and cell biology 20050801

Title: Analysis of mitochondrial membrane potential in the cells by microchip flow cytometry.

Journal: Electrophoresis 20050801

Title: Rotenoids and isoflavones from Sarcolobus globosus.

Journal: Planta medica 20050801

Title: Behavioral differences in a rotenone-induced hemiparkinsonian rat model developed following intranigral or median forebrain bundle infusion.

Journal: Brain research 20050727

Title: Estrogen-induced G1/S transition of G0-arrested estrogen-dependent breast cancer cells is regulated by mitochondrial oxidant signaling.

Journal: Oncogene 20050721

Title: PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone.

Journal: FEBS letters 20050718

Title: Targeting the NAD7 subunit to mitochondria restores a functional complex I and a wild type phenotype in the Nicotiana sylvestris CMS II mutant lacking nad7.

Journal: The Journal of biological chemistry 20050715

Title: Inhibitor studies on non-photochemical plastoquinone reduction and H(2) photoproduction in Chlamydomonas reinhardtii.

Journal: Biochimica et biophysica acta 20050715

Title: Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster.

Journal: Journal of agricultural and food chemistry 20050713

Title: Acute intranigral infusion of rotenone in rats causes progressive biochemical lesions in the striatum similar to Parkinson's disease.

Journal: Brain research 20050712

Title: Effect of sildenafil citrate and a nitric oxide donating sildenafil derivative, NCX 911, on cavernosal relaxation and superoxide formation in hypercholesterolaemic rabbits.

Journal: European journal of pharmacology 20050711

Title: Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries.

Journal: American journal of physiology. Heart and circulatory physiology 20050701

Title: Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders.

Journal: Journal of molecular and cellular cardiology 20050701

Title: Increased sensitivity of striatal dopamine release to H2O2 upon chronic rotenone treatment.

Journal: Free radical biology & medicine 20050701

Title: Regulating expressions of cyclin D1, pRb, and anti-cancer effects of deguelin on human Burkitt's lymphoma Daudi cells in vitro.

Journal: Acta pharmacologica Sinica 20050701

Title: Processes and components participating in the generation of intrinsic optical signal changes in vitro.

Journal: The European journal of neuroscience 20050701

Title: Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells.

Journal: Histochemistry and cell biology 20050701

Title: Toxin-induced models of Parkinson's disease.

Journal: NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 20050701

Title: Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species.

Journal: Blood 20050615

Title: Hypoxic augmentation of Ca2+ channel currents requires a functional electron transport chain.

Journal: The Journal of biological chemistry 20050610

Title: Inhibition of complex I of the electron transport chain causes O2-. -mediated mitochondrial outgrowth.

Journal: American journal of physiology. Cell physiology 20050601

Title: Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation.

Journal: Neurochemistry international 20050601

Title: Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism.

Journal: International journal of molecular medicine 20050601

Title: Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway.

Journal: British journal of haematology 20050601

Title: Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10.

Journal: Journal of neurochemistry 20050601

Title: Isolation and structural elucidation of a novel rotenoid from the seeds of Clitoria fairchildiana.

Journal: Natural product research 20050601

Title: Effect of deguelin on UVB-induced skin carcinogenesis.

Journal: Journal of chemotherapy (Florence, Italy) 20050601

Title: Angiotensin II protects cultured midbrain dopaminergic neurons against rotenone-induced cell death.

Journal: Brain research 20050531

Title: Sleep disturbances in the rotenone animal model of Parkinson disease.

Journal: Brain research 20050503

Title: Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats.

Journal: Journal of neuroscience research 20050501

Title: Ca2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I.

Journal: Journal of neurochemistry 20050501

Title: Rotenone induces oxidative stress and dopaminergic neuron damage in organotypic substantia nigra cultures.

Journal: Brain research. Molecular brain research 20050324

Title: Resistance to endotoxic shock in endothelial nitric-oxide synthase (eNOS) knock-out mice: a pro-inflammatory role for eNOS-derived no in vivo.

Journal: The Journal of biological chemistry 20050318

Title: Possible involvement of Ca2+ signaling in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells.

Journal: Neuroscience letters 20050311

Title: Inducers of oxidative stress block ciliary neurotrophic factor activation of Jak/STAT signaling in neurons.

Journal: Journal of neurochemistry 20050301

Title: 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, from the roots of Derris trifoliata.

Journal: Phytochemistry 20050301

Title: Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

Journal: The Journal of biological chemistry 20050211

Title: Neuroprotective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline on cultured rat mesencephalic neurons in the presence or absence of various neurotoxins.

Journal: Brain research 20050208

Title: Rotenone-induced caspase 9/3-independent and -dependent cell death in undifferentiated and differentiated human neural stem cells.

Journal: Journal of neurochemistry 20050201

Title: Hyperglycemia activates JAK2 signaling pathway in human failing myocytes via angiotensin II-mediated oxidative stress.

Journal: Diabetes 20050201

Title: A preferential role for glycolysis in preventing the anoxic depolarization of rat hippocampal area CA1 pyramidal cells.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050126

Title: Prostaglandin F2alpha potentiates the calcium dependent activation of mitochondrial metabolism in luteal cells.

Journal: Cell calcium 20050101

Title: Inhibition of MPP+-induced mitochondrial damage and cell death by trifluoperazine and W-7 in PC12 cells.

Journal: Neurochemistry international 20050101

Title: Effect of sesamin in Acanthopanax senticosus HARMS on behavioral dysfunction in rotenone-induced parkinsonian rats.

Journal: Biological & pharmaceutical bulletin 20050101

Title: Redox regulation of p38 MAPK activation and expression of ICAM-1 and heme oxygenase-1 in human alveolar epithelial (A549) cells.

Journal: Antioxidants & redox signaling 20050101

Title: Intracellular dopamine oxidation mediates rotenone-induced apoptosis in PC12 cells.

Journal: Acta pharmacologica Sinica 20050101

Title: The results of five coded compounds: genistein, metaproterenol, rotenone, p-anisidine and resorcinol tested in the pH 6.7 Syrian hamster embryo cell morphological transformation assay.

Journal: Mutagenesis 20050101

Title: H2O2-induced changes in mitochondrial activity in isolated mouse pancreatic acinar cells.

Journal: Molecular and cellular biochemistry 20050101

Title: In vitro search for synergy between flavonoids and epirubicin on multidrug-resistant cancer cells.

Journal: In vivo (Athens, Greece) 20050101

Title: The effect of endogenous dopamine in rotenone-induced toxicity in PC12 cells.

Journal: Antioxidants & redox signaling 20050101

Title: Energy status, ubiquitin proteasomal function, and oxidative stress during chronic and acute complex I inhibition with rotenone in mesencephalic cultures.

Journal: Antioxidants & redox signaling 20050101

Title: Rotenone induces aggregation of gamma-tubulin protein and subsequent disorganization of the centrosome: relevance to formation of inclusion bodies and neurodegeneration.

Journal: Neuroscience 20050101

Title: Fatality after deliberate ingestion of the pesticide rotenone: a case report.

Journal: Critical care (London, England) 20050101

Title: Protective effect of melatonin on rotenone plus Ca2+-induced mitochondrial oxidative stress and PC12 cell death.

Journal: Antioxidants & redox signaling 20050101

Title: [Respiration of wheat root cells under simultaneous inhibition of parts I and III of the electron transport chain of mitochondria by rotenone and antimycine A].

Journal: Tsitologiia 20050101

Title: Mitochondrial activation and the pyruvate paradox in a human cell line.

Journal: FEBS letters 20041217

Title: Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease.

Journal: Physiology & behavior 20041215

Title: Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells.

Journal: The Journal of biological chemistry 20041210

Title: Cd2+ versus Ca2+-produced mitochondrial membrane permeabilization: a proposed direct participation of respiratory complexes I and III.

Journal: Chemico-biological interactions 20041207

Title: Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I.

Journal: Nature 20041202

Title: Rotenone induces apoptosis via activation of bad in human dopaminergic SH-SY5Y cells.

Journal: The Journal of pharmacology and experimental therapeutics 20041201

Title: Selective modulation of ligand-gated P2X purinoceptor channels by acute hypoxia is mediated by reactive oxygen species.

Journal: Molecular pharmacology 20041201

Title: The effect of rotenone on the urinary ethanol cycle in rats fed ethanol intragastrically.

Journal: Experimental and molecular pathology 20041201

Title: Rotenone potentiates dopamine neuron loss in animals exposed to lipopolysaccharide prenatally.

Journal: Experimental neurology 20041201

Title: Lipopolysaccharide induces matrix metalloproteinase-9 expression via a mitochondrial reactive oxygen species-p38 kinase-activator protein-1 pathway in Raw 264.7 cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20041201

Title: Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.

Journal: Journal of neurochemistry 20041201

Title: Strong calcium entry activates mitochondrial superoxide generation, upregulating kinase signaling in hippocampal neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201

Title: Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201

Title: Assay and subcellular localization of pyrroline-5-carboxylate dehydrogenase in rat liver.

Journal: Biochimica et biophysica acta 20041118

Title: Blockade of electron transport during ischemia protects cardiac mitochondria.

Journal: The Journal of biological chemistry 20041112

Title: Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041101

Title: The ND1 gene of complex I is a mutational hot spot for Leber's hereditary optic neuropathy.

Journal: Annals of neurology 20041101

Title: Pesticides and organic agriculture.

Journal: Environmental health perspectives 20041101

Title: Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease.

Journal: Chemical research in toxicology 20041101

Title: Menadione reduces rotenone-induced cell death in cerebellar granule neurons.

Journal: Neuroreport 20041005

Title: Leber hereditary optic neuropathy mtDNA mutations disrupt glutamate transport in cybrid cell lines.

Journal: Brain : a journal of neurology 20041001

Title: Severe impairment of nucleotide synthesis through inhibition of mitochondrial respiration.

Journal: Nucleosides, nucleotides & nucleic acids 20041001

Title: Molecular mechanisms of deguelin-induced apoptosis in transformed human bronchial epithelial cells.

Journal: Biochemical pharmacology 20040915

Title: Analysis of alpha-synuclein-associated proteins by quantitative proteomics.

Journal: The Journal of biological chemistry 20040910

Title: Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

Title: Hydrogen peroxide generated at the level of mitochondria in response to peroxynitrite promotes U937 cell death via inhibition of the cytoprotective signalling mediated by cytosolic phospholipase A2.

Journal: Cell death and differentiation 20040901

Title: Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition.

Journal: Journal of neurochemistry 20040901

Title: Coordinated behavior of mitochondria in both space and time: a reactive oxygen species-activated wave of mitochondrial depolarization.

Journal: Biophysical journal 20040901

Title: Autofluorescence lifetime imaging of cultivated cells using a UV picosecond laser diode.

Journal: Journal of fluorescence 20040901

Title: Protective effects of erdosteine on rotenone-induced oxidant injury in liver tissue.

Journal: Toxicology and industrial health 20040901

Title: L-DOPA reverses the hypokinetic behaviour and rigidity in rotenone-treated rats.

Journal: Behavioural brain research 20040831

Title: Segregation pattern and biochemical effect of the G3460A mtDNA mutation in 27 members of LHON family.

Journal: Journal of the neurological sciences 20040830

Title: Stimulators of AMP-activated protein kinase inhibit the respiratory burst in human neutrophils.

Journal: FEBS letters 20040827

Title: Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis.

Journal: Human molecular genetics 20040815

Title: Mitochondrial function is required for hydrogen peroxide-induced growth factor receptor transactivation and downstream signaling.

Journal: The Journal of biological chemistry 20040813

Title: Intracellular pH and KATP channel activity in dorsal vagal neurons of juvenile rats in situ during metabolic disturbances.

Journal: Brain research 20040813

Title: Effects of iptakalim on rotenone-induced cytotoxicity and dopamine release from PC12 cells.

Journal: Neuroscience letters 20040805

Title: Effect of uncouplers on endogenous respiration and ferrous iron oxidation in a chemolithoautotrophic bacterium Acidithiobacillus (Thiobacillus) ferrooxidans.

Journal: FEMS microbiology letters 20040801

Title: Growth inhibition dependent on reactive oxygen species generated by C9-UK-2A, a derivative of the antifungal antibiotic UK-2A, in Saccharomyces cerevisiae.

Journal: The Journal of antibiotics 20040801

Title: Effects of mitochondrial dysfunction on glutamate receptor-mediated neurotoxicity in cultured rat spinal motor neurons.

Journal: Brain research 20040723

Title: Apoptosis induction by the natural product cancer chemopreventive agent deguelin is mediated through the inhibition of mitochondrial bioenergetics.

Journal: Apoptosis : an international journal on programmed cell death 20040701

Title: Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor.

Journal: Free radical biology & medicine 20040615

Title: Rotenone-sensitive mitochondrial potential in Phytomonas serpens: electrophoretic Ca(2+) accumulation.

Journal: Biochimica et biophysica acta 20040607

Title: Protective effect of 1-methyl-1,2,3,4-tetrahydroisoquinoline against dopaminergic neurodegeneration in the extrapyramidal structures produced by intracerebral injection of rotenone.

Journal: The international journal of neuropsychopharmacology 20040601

Title: Stable compounds of cigarette smoke induce endothelial superoxide anion production via NADPH oxidase activation.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040601

Title: Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver.

Journal: Biochemical pharmacology 20040601

Title: Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone.

Journal: Experimental neurology 20040601

Title: Proximal tubular cytochrome c efflux: determinant, and potential marker, of mitochondrial injury.

Journal: Kidney international 20040601

Title: Race-specific differences in endothelial function: predisposition of African Americans to vascular diseases.

Journal: Circulation 20040601

Title: Cancer chemopreventive activity of rotenoids from Derris trifoliata.

Journal: Planta medica 20040601

Title: Neuroprotective effect of fraxetin and myricetin against rotenone-induced apoptosis in neuroblastoma cells.

Journal: Brain research 20040529

Title: Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators.

Journal: The Biochemical journal 20040515

Title: Oxidation and reduction of pyridine nucleotides in alamethicin-permeabilized plant mitochondria.

Journal: The Biochemical journal 20040515

Title: 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells.

Journal: Journal of neuroscience research 20040515

Title: The neurobehavioral changes induced by bilateral rotenone lesion in medial forebrain bundle of rats are reversed by L-DOPA.

Journal: Behavioural brain research 20040505

Title: Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries.

Journal: The Journal of physiology 20040501

Title: Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501

Title: The value of DNA methylation analysis in basic, initial toxicity assessments.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501

Title: Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I.

Journal: The Journal of biological chemistry 20040423

Title: Redox activity associated with the maturation and capacitation of mammalian spermatozoa.

Journal: Free radical biology & medicine 20040415

Title: Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules.

Journal: American journal of physiology. Renal physiology 20040401

Title: The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells.

Journal: The Journal of physiology 20040401

Title: Rotenone induces non-specific central nervous system and systemic toxicity.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040401

Title: Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway.

Journal: Human molecular genetics 20040401

Title: Chronic administration of rotenone increases levels of nitric oxide and lipid peroxidation products in rat brain.

Journal: Experimental neurology 20040401

Title: Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?

Journal: Diabetes 20040401

Title: Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells.

Journal: Kidney international 20040401

Title: Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice.

Journal: Journal of neuropathology and experimental neurology 20040401

Title: Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions.

Journal: The Journal of biological chemistry 20040312

Title: NADH oxidase activity of rat cardiac sarcoplasmic reticulum regulates calcium-induced calcium release.

Journal: Circulation research 20040305

Title: NADH-ubiquinone oxidoreductase activity in the kinetoplasts of the plant trypanosomatid Phytomonas serpens.

Journal: Parasitology research 20040301

Title: Assay of mitochondrial functions by resazurin in vitro.

Journal: Acta pharmacologica Sinica 20040301

Title: Cytotoxic compounds from Mundulea chapelieri from the Madagascar Rainforest.

Journal: Journal of natural products 20040301

Title: Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia.

Journal: European journal of cell biology 20040301

Title: Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225

Title: Deguelin-induced inhibition of cyclooxygenase-2 expression in human bronchial epithelial cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040201

Title: Rotenone and rotenoids in cubè resins, formulations, and residues on olives.

Journal: Journal of agricultural and food chemistry 20040128

Title: Analysis of the mechanism by which calcium negatively regulates the tyrosine phosphorylation cascade associated with sperm capacitation.

Journal: Journal of cell science 20040115

Title: Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum.

Journal: Biochimica et biophysica acta 20040105

Title: Oxidative phosphorylation and rotenone-insensitive malate- and NADH-quinone oxidoreductases in Plasmodium yoelii yoelii mitochondria in situ.

Journal: The Journal of biological chemistry 20040102

Title: Rotenone induces disassembly of the Golgi apparatus in the rat dopaminergic neuroblastoma B65 cell line.

Journal: Neuroscience letters 20040102

Title: Production of endogenous matrix superoxide from mitochondrial complex I leads to activation of uncoupling protein 3.

Journal: FEBS letters 20040102

Title: Early ionic and membrane potential changes caused by the pesticide rotenone in striatal cholinergic interneurons.

Journal: Experimental neurology 20040101

Title: Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes.

Journal: Free radical biology & medicine 20040101

Title: Cancer chemopreventive activity of rotenoids from Derris trifoliata.

Journal: Planta medica 20040101

Title: The modulation of action potential generation by calcium-induced calcium release is enhanced by mitochondrial inhibitors in mudpuppy parasympathetic neurons.

Journal: Neuroscience 20040101

Title: Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport.

Journal: Epilepsy research 20040101

Title: Antimycin A treatment decreases respiratory internal rotenone-insensitive NADH oxidation capacity in potato leaves.

Journal: BMC plant biology 20040101

Title: Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells.

Journal: Molecular cancer 20040101

Title: Sensitivity of zebrafish to environmental toxins implicated in Parkinson's disease.

Journal: Neurotoxicology and teratology 20040101

Title: [Rotenone-insensitive NADH oxydation in mitochondrial suspension occurs by NADH dehydrogenase of respiratory chain fragments].

Journal: Biofizika 20040101

Title: [Ultrastructural characteristics of mitochondria during cell adaptation to rotenone].

Journal: Tsitologiia 20040101

Title: Rotenone, a mitochondrial electron transport inhibitor, ameliorates ischemia-reperfusion-induced intestinal mucosal damage in rats.

Journal: Redox report : communications in free radical research 20040101

Title: Caenorhabditis elegans MPP+ model of Parkinson's disease for high-throughput drug screenings.

Journal: Neuro-degenerative diseases 20040101

Title: Redox-dependent modulation of aconitase activity in intact mitochondria.

Journal: Biochemistry 20031223

Title: Dopamine is involved in selectivity of dopaminergic neuronal death by rotenone.

Journal: Neuroreport 20031219

Title: Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs.

Journal: American journal of respiratory cell and molecular biology 20031201

Title: Proximal tubular cholesterol loading after mitochondrial, but not glycolytic, blockade.

Journal: American journal of physiology. Renal physiology 20031201

Title: Rotenone increases glutamate-induced dopamine release but does not affect hydroxyl-free radical formation in rat striatum.

Journal: Synapse (New York, N.Y.) 20031201

Title: MPP+ analogs acting on mitochondria and inducing neuro-degeneration.

Journal: Current medicinal chemistry 20031201

Title: Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

Journal: Free radical biology & medicine 20031201

Title: Cytosol-mitochondria transfer of reducing equivalents by a lactate shuttle in heterotrophic Euglena.

Journal: European journal of biochemistry 20031201

Title: Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes.

Journal: The Journal of biological chemistry 20031128

Title: Mechanism of toxicity in rotenone models of Parkinson's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031126

Title: Inhibitory effects on mitochondrial complex I of semisynthetic mono-tetrahydrofuran acetogenin derivatives.

Journal: Bioorganic & medicinal chemistry letters 20031117

Title: An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH-SY5Y cells.

Journal: Journal of neuroscience research 20031115

Title: Mechanism for generation of hydrogen peroxide and change of mitochondrial membrane potential during rotenone-induced apoptosis.

Journal: Life sciences 20031107

Title: Alpha-synuclein expression in HEK293 cells enhances the mitochondrial sensitivity to rotenone.

Journal: Neuroscience letters 20031106

Title: Fe(II)-induced DNA damage in alpha-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay.

Journal: Journal of neurochemistry 20031101

Title: Mode of action of pyrazinamide: disruption of Mycobacterium tuberculosis membrane transport and energetics by pyrazinoic acid.

Journal: The Journal of antimicrobial chemotherapy 20031101

Title: The pesticide rotenone induces caspase-3-mediated apoptosis in ventral mesencephalic dopaminergic neurons.

Journal: Journal of neurochemistry 20031101

Title: Concise synthesis of the chemopreventitive agent (+/-)-deguelin via a key 6-endo hydroarylation.

Journal: Organic letters 20031030

Title: An increase in intracellular calcium concentration that is induced by basolateral CO2 in rabbit renal proximal tubule.

Journal: American journal of physiology. Renal physiology 20031001

Title: Alterations of mitochondria in peripheral blood mononuclear cells of vitiligo patients.

Journal: Pigment cell research 20031001

Title: Hypoxia and stretch regulate intercellular communication in vascular smooth muscle cells through reactive oxygen species formation.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20031001

Title: Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis.

Journal: Phytochemistry 20031001

Title: Agonist-induced calcium and oxidative stress responses in endothelial cells.

Journal: Biochemical Society transactions 20031001

Title: Mechanism of primary Cd2+-induced rat liver mitochondria dysfunction: discrete modes of Cd2+ action on calcium and thiol-dependent domains.

Journal: Toxicology and applied pharmacology 20031001

Title: Control of ascorbate synthesis by respiration and its implications for stress responses.

Journal: Plant physiology 20031001

Title: Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.

Journal: Pest management science 20031001

Title: The production of reactive oxygen species in intact isolated nerve terminals is independent of the mitochondrial membrane potential.

Journal: Neurochemical research 20031001

Title: Sources for superoxide release: lessons from blockade of electron transport, NADPH oxidase, and anion channels in diaphragm.

Journal: Antioxidants & redox signaling 20031001

Title: NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons.

Journal: The Journal of biological chemistry 20030926

Title: Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism.

Journal: The Journal of biological chemistry 20030926

Title: Production of reactive oxygen species by mitochondria: central role of complex III.

Journal: The Journal of biological chemistry 20030919

Title: Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries.

Journal: Circulation research 20030919

Title: Stimulation by surangin B of endogenous amino acid release from synaptosomes.

Journal: Toxicon : official journal of the International Society on Toxinology 20030915

Title: Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.

Journal: Journal of neurochemistry 20030901

Title: Role of nitric oxide in rotenone-induced nigro-striatal injury.

Journal: Journal of neurochemistry 20030901

Title: Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species.

Journal: FEBS letters 20030828

Title: Vitamin D enhances caspase-dependent and -independent TNFalpha-induced breast cancer cell death: The role of reactive oxygen species and mitochondria.

Journal: International journal of cancer 20030820

Title: Differential effects of vitamin E and three hydrophilic antioxidants on the actinomycin D-induced and colcemid-accelerated apoptosis in human leukemia CMK-7 cell line.

Journal: Molecular and cellular biochemistry 20030801

Title: Effect of thyroid state on H2O2 production by rat liver mitochondria.

Journal: Molecular and cellular endocrinology 20030731

Title: Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030716

Title: Effect of fraxetin and myricetin on rotenone-induced cytotoxicity in SH-SY5Y cells: comparison with N-acetylcysteine.

Journal: European journal of pharmacology 20030704

Title: Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the mitochondrial benzodiazepine receptor.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701

Title: Models of Parkinson's disease.

Journal: Movement disorders : official journal of the Movement Disorder Society 20030701

Title: Effect of voluntary exercise on H2O2 release by subsarcolemmal and intermyofibrillar mitochondria.

Journal: Free radical biology & medicine 20030701

Title: Rotenone alpha-oxime.

Journal: Acta crystallographica. Section C, Crystal structure communications 20030701

Title: Effect of electron-transport inhibitors on the generation of reactive oxygen species by pea mitochondria during succinate oxidation.

Journal: Biochemistry. Biokhimiia 20030701

Title: Rapid reduction of ATP synthesis and lack of free radical formation by MPP+ in rat brain synaptosomes and mitochondria.

Journal: Brain research 20030613

Title: Apoptosis triggered redistribution of caspase-9 from cytoplasm to mitochondria.

Journal: FEBS letters 20030605

Title: Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis.

Journal: Cell death and differentiation 20030601

Title: Prenylated isoflavonoids from Millettia pervilleana.

Journal: Phytochemistry 20030601

Title: K-ATP channel independent effects of pinacidil on ATP production in isolated cardiomyocyte or pancreatic beta-cell mitochondria.

Journal: Biochemical pharmacology 20030601

Title: Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons.

Journal: Antioxidants & redox signaling 20030601

Title: 24-well plate spectrophotometric assay for preliminary screening of metabolic activity.

Journal: Assay and drug development technologies 20030601

Title: The 9.8 kDa subunit of complex I, related to bacterial Na(+)-translocating NADH dehydrogenases, is required for enzyme assembly and function in Neurospora crassa.

Journal: Journal of molecular biology 20030530

Title: Ca2+-induced oxidative stress in brain mitochondria treated with the respiratory chain inhibitor rotenone.

Journal: FEBS letters 20030522

Title: Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells.

Journal: The Journal of physiology 20030501

Title: Selective microglial activation in the rat rotenone model of Parkinson's disease.

Journal: Neuroscience letters 20030501

Title: Leaf mitochondria modulate whole cell redox homeostasis, set antioxidant capacity, and determine stress resistance through altered signaling and diurnal regulation.

Journal: The Plant cell 20030501

Title: Inhibitory activities of three annonaceous acetogenins on NADH oxidase of chicken liver mitochondria.

Journal: Biological & pharmaceutical bulletin 20030501

Title: Molecular mechanisms of dopaminergic neurodegeneration: genetic and environmental basis.

Journal: Annals of the New York Academy of Sciences 20030501

Title: Circadian rhythms of oxidative phosphorylation: effects of rotenone and melatonin on isolated rat brain mitochondria.

Journal: Chronobiology international 20030501

Title: 1-methyl-1,2,3,4-tetrahydroisoquinoline protects against rotenone-induced mortality and biochemical changes in rat brain.

Journal: European journal of pharmacology 20030418

Title: Mitochondrial effects with ceramide-induced cardiac apoptosis are different from those of palmitate.

Journal: Archives of biochemistry and biophysics 20030415

Title: Tigliane diterpenes from the latex of Euphorbia obtusifolia with inhibitory activity on the mammalian mitochondrial respiratory chain.

Journal: Journal of ethnopharmacology 20030401

Title: 1-Methyl-4-phenylpyridinium accumulates in cerebellar granule neurons via organic cation transporter 3.

Journal: Journal of neurochemistry 20030401

Title: Deguelin suppresses the formation of carcinogen-induced aberrant crypt foci in the colon of CF-1 mice.

Journal: International journal of cancer 20030310

Title: Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production.

Journal: The Journal of biological chemistry 20030307

Title: Blue light-induced generation of reactive oxygen species in photoreceptor ellipsoids requires mitochondrial electron transport.

Journal: Investigative ophthalmology & visual science 20030301

Title: Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death.

Journal: Journal of neurochemistry 20030301

Title: Signaling of hypoxia-induced autonomous proliferation of endothelial cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030301

Title: Rotenone and oxalic acid as alternative acaricidal treatments for Varroa destructor in honeybee colonies.

Journal: Veterinary parasitology 20030227

Title: AKT and the phosphatidylinositol 3-kinase/AKT pathway: important molecular targets for lung cancer prevention and treatment.

Journal: Journal of the National Cancer Institute 20030219

Title: Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells.

Journal: Journal of the National Cancer Institute 20030219

Title: External alternative NADH dehydrogenase of Saccharomyces cerevisiae: a potential source of superoxide.

Journal: Free radical biology & medicine 20030215

Title: Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215

Title: Redox signaling in the growth and development of colonial hydroids.

Journal: The Journal of experimental biology 20030201

Title: Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats.

Journal: Journal of neurochemistry 20030201

Title: Assay of mitochondrial respiratory chain complex I in human lymphocytes and cultured skin fibroblasts.

Journal: Biochemical and biophysical research communications 20030131

Title: Determination of rotenone in river water utilizing packed capillary column switching liquid chromatography with UV and time-of-flight mass spectrometric detection.

Journal: Journal of chromatography. A 20030103

Title: Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

Journal: Experimental neurology 20030101

Title: Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices.

Journal: Experimental neurology 20030101

Title: Non-synaptic release of [3H]noradrenaline in response to oxidative stress combined with mitochondrial dysfunction in rat hippocampal slices.

Journal: Neuroscience 20030101

Title: Animal models of Parkinson's disease in rodents induced by toxins: an update.

Journal: Journal of neural transmission. Supplementum 20030101

Title: The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism.

Journal: Neuroscience 20030101

Title: Inhibitory effects of Bcl-2 on mitochondrial respiration.

Journal: Physiological research 20030101

Title: Cyclosporin A-sensitive cytochrome c release and activation of external pathway of NADH oxidation in liver mitochondria due to pore opening by acidification of phosphate-containing incubation medium.

Journal: Bioscience reports 20030101

Title: Participation of chloroplasts in plant apoptosis.

Journal: Bioscience reports 20030101

Title: Effect of mitochondrial inhibitors on type I cells.

Journal: Advances in experimental medicine and biology 20030101

Title: Cytoprotective and anticancer properties of coenzyme Q versus capsaicin.

Journal: BioFactors (Oxford, England) 20030101

Title: Mitochondrial complex I inhibition produces selective damage to hippocampal subfield CA1 in organotypic slice cultures.

Journal: Neurotoxicity research 20030101

Title: Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021215

Title: Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)+ oxidation-reduction state.

Journal: The Biochemical journal 20021201

Title: Prostaglandin A1 inhibits rotenone-induced apoptosis in SH-SY5Y cells.

Journal: Journal of neurochemistry 20021201

Title: Deguelin inhibits the growth of colon cancer cells through the induction of apoptosis and cell cycle arrest.

Journal: European journal of cancer (Oxford, England : 1990) 20021201

Title: An inflammatory review of Parkinson's disease.

Journal: Progress in neurobiology 20021201

Title: The respiratory chain complex thresholds in mitochondria of a Drosophila subobscura mutant strain.

Journal: Biochimie 20021201

Title: [Genetics and environmental factors of Parkinson disease].

Journal: Revue neurologique 20021201

Title: Topology of superoxide production from different sites in the mitochondrial electron transport chain.

Journal: The Journal of biological chemistry 20021122

Title: Possible involvement of both mitochondria- and endoplasmic reticulum-dependent caspase pathways in rotenone-induced apoptosis in human neuroblastoma SH-SY5Y cells.

Journal: Neuroscience letters 20021115

Title: Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species.

Journal: American journal of physiology. Lung cellular and molecular physiology 20021101

Title: CNS neurons express two distinct plasma membrane electron transport systems implicated in neuronal viability.

Journal: Journal of neurochemistry 20021101

Title: Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status.

Journal: Archives of biochemistry and biophysics 20021101

Title: Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats.

Journal: Behavioural brain research 20021017

Title: Respiratory function in cybrid cell lines carrying European mtDNA haplogroups: implications for Leber's hereditary optic neuropathy.

Journal: Biochimica et biophysica acta 20021009

Title: Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax.

Journal: Journal of neurochemistry 20021001

Title: Near UV quantum yields for rotenone and piperonyl butoxide.

Journal: The Analyst 20021001

Title: Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death.

Journal: The Journal of biological chemistry 20020906

Title: Comparison of the effects of ammonia on brain mitochondrial function in rats and gulf toadfish.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020901

Title: Mitochondrial-driven bicarbonate transport supports photosynthesis in a marine microalga.

Journal: Plant physiology 20020901

Title: Proteasome inhibitors stimulate activator protein-1 pathway via reactive oxygen species production.

Journal: FEBS letters 20020828

Title: Rotenone-insensitive NADH dehydrogenase is a potential source of superoxide in procyclic Trypanosoma brucei mitochondria.

Journal: Molecular and biochemical parasitology 20020828

Title: An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815

Title: Activation of adenosine triphosphate-sensitive potassium channels confers protection against rotenone-induced cell death: therapeutic implications for Parkinson's disease.

Journal: Journal of neuroscience research 20020815

Title: Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis.

Journal: American journal of physiology. Endocrinology and metabolism 20020801

Title: High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells.

Journal: Endocrinology 20020801

Title: Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis.

Journal: Carcinogenesis 20020801

Title: NADH oxidation and NAD+ reduction catalysed by tightly coupled inside-out vesicles from Paracoccus denitrificans.

Journal: European journal of biochemistry 20020801

Title: Role of membrane-associated Ca+ dependent matrix metalloprotease-2 in the oxidant activation of Ca2+Atpase by tertiary butylhydroperoxide.

Journal: Molecular and cellular biochemistry 20020801

Title: Expression of mutant alpha-synucleins enhances dopamine transporter-mediated MPP+ toxicity in vitro.

Journal: Neuroreport 20020719

Title: Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811.

Journal: Molecular pharmacology 20020701

Title: The fetal and neonatal brain protein neuronatin protects PC12 cells against certain types of toxic insult.

Journal: Brain research. Developmental brain research 20020630

Title: Mouse model of optic neuropathy caused by mitochondrial complex I dysfunction.

Journal: Neuroscience letters 20020628

Title: Specific up-regulation of GADD153/CHOP in 1-methyl-4-phenyl-pyridinium-treated SH-SY5Y cells.

Journal: Journal of neuroscience research 20020615

Title: Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species.

Journal: The Journal of biological chemistry 20020607

Title: Sensory neurons respond to hypoxia with NO production associated with mitochondria.

Journal: Molecular and cellular neurosciences 20020601

Title: Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway.

Journal: Journal of the American Society of Nephrology : JASN 20020501

Title: Inhibitors of mitochondrial complex I attenuate the accumulation of hypoxia-inducible factor-1 during hypoxia in Hep3B cells.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020501

Title: ATP-driven, Na(+)-independent inward Cl- pumping in neuroblastoma cells.

Journal: Journal of neurochemistry 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Influence of mitochondrial inhibition on global and local [Ca(2+)](I) in rat tail artery.

Journal: Circulation research 20020419

Title: Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020401

Title: Mechanisms of oxygen sensing in human trophoblast cells.

Journal: Placenta 20020401

Title: [Inhibitors of complex I and II of the mitochondrial respiratory chain].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020401

Title: [Mutagens inducing mutations in mammalian mitochondrial DNA].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020401

Title: The second coenzyme Q1 binding site of bovine heart NADH: coenzyme Q oxidoreductase.

Journal: Journal of bioenergetics and biomembranes 20020401

Title: Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1(NQO1).

Journal: Free radical research 20020401

Title: Novel FMN-containing rotenone-insensitive NADH dehydrogenase from Trypanosoma brucei mitochondria: isolation and characterization.

Journal: Biochemistry 20020305

Title: Antiinflammatory activity of rotenoids from Clitoria fairchildiana.

Journal: Phytotherapy research : PTR 20020301

Title: Reactive oxygen species from mitochondria mediate SW480 cells apoptosis induced by Na2SeO3.

Journal: Biological trace element research 20020301

Title: The effects of phytochemical pesticides on the growth of cultured invertebrate and vertebrate cells.

Journal: Pest management science 20020301

Title: [Modification of the analytical method for rotenoids in plants].

Journal: Se pu = Chinese journal of chromatography 20020301

Title: Lack of contribution of mitochondrial electron transport to acute O(2) sensing in model airway chemoreceptors.

Journal: Biochemical and biophysical research communications 20020222

Title: Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors.

Journal: The Journal of biological chemistry 20020215

Title: Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging.

Journal: Biochimica et biophysica acta 20020215

Title: Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020201

Title: Respiration and mitochondrial membrane potential are not required for apoptosis and anti-apoptotic action of Bcl-2 in HeLa cells.

Journal: Biochemistry. Biokhimiia 20020201

Title: Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease.

Journal: Journal of neurochemistry 20020101

Title: ATP-independent anoxic activation of ATP-sensitive K+ channels in dorsal vagal neurons of juvenile mice in situ.

Journal: Neuroscience 20020101

Title: Tissue-specific mitochondrial production of H2O2: its dependence on substrates and sensitivity to inhibitors.

Journal: Methods in enzymology 20020101

Title: [Disturbances in biliary secretion during tissue hypoxia and attempts at their corrections].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20020101

Title: The targets of 2,2',5,5'-tetrachlorobiphenyl in the respiratory chain of rat liver mitochondria revealed by modular kinetic analysis.

Journal: Molecular biology reports 20020101

Title: Transepithelial glucose transport and metabolism in BeWo choriocarcinoma cells.

Journal: Placenta 20020101

Title: Selective action of acetogenin mitochondrial complex I inhibitors.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

Title: Vitamin E succinate protects hepatocytes against the toxic effect of reactive oxygen species generated at mitochondrial complexes I and III by alkylating agents.

Journal: Chemico-biological interactions 20011221

Title: Rotenone-induced G2/M cell cycle arrest and apoptosis in a human B lymphoma cell line PW.

Journal: Biochemical and biophysical research communications 20011221

Title: Endothelin-1 production is enhanced by rotenone, a mitochondrial complex I inhibitor, in cultured rat cardiomyocytes.

Journal: Journal of cardiovascular pharmacology 20011201

Title: The endosomal compartment is an insulin-sensitive recruitment site for GLUT4 and GLUT1 glucose transporters in cardiac myocytes.

Journal: Endocrinology 20011201

Title: Opioid receptor modulation of a metabolically sensitive ion channel in rat amygdala neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201

Title: Effect of mitochondrial electron transport chain inhibitors on superoxide radical generation in rat hippocampal and striatal slices.

Journal: Antioxidants & redox signaling 20011201

Title: Selected presentations and general discussion: session IX summary and research needs.

Journal: Neurotoxicology 20011201

Title: Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithium.

Journal: Brain research 20011116

Title: Endothelin-1 stimulates cardiomyocyte injury during mitochondrial dysfunction in culture.

Journal: European journal of pharmacology 20011116

Title: Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons.

Journal: Free radical biology & medicine 20011115

Title: Rotenone inhibits the mitochondrial permeability transition-induced cell death in U937 and KB cells.

Journal: The Journal of biological chemistry 20011102

Title: Mammalian TOR: a homeostatic ATP sensor.

Journal: Science (New York, N.Y.) 20011102

Title: Chemoprevention of azoxymethane-induced rat colon carcinogenesis by dietary capsaicin and rotenone.

Journal: International journal of oncology 20011101

Title: Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway.

Journal: Arthritis and rheumatism 20011101

Title: Stimulation of cardiac glucose transport by inhibitors of oxidative phosphorylation.

Journal: Life sciences 20011005

Title: Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa.

Journal: Biology of reproduction 20011001

Title: Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor.

Journal: The Journal of physiology 20011001

Title: A flow cytometry assay simultaneously detects independent apoptotic parameters.

Journal: Cytometry 20011001

Title: The insecticide target in the PSST subunit of complex I.

Journal: Pest management science 20011001

Title: Nickel requires hypoxia-inducible factor-1 alpha, not redox signaling, to induce plasminogen activator inhibitor-1.

Journal: American journal of physiology. Lung cellular and molecular physiology 20010901

Title: Mitochondrial electron transport inhibitors cause lipid peroxidation-dependent and -independent cell death: protective role of antioxidants.

Journal: Archives of biochemistry and biophysics 20010901

Title: Parkinson disease: etiology, pathogenesis and future of gene therapy.

Journal: Neuroscience research 20010901

Title: Inhibition of glucose transport by cyclic GMP in cardiomyocytes.

Journal: Life sciences 20010810

Title: H(2)O(2)-induced O(2) production by a non-phagocytic NAD(P)H oxidase causes oxidant injury.

Journal: The Journal of biological chemistry 20010803

Title: Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions.

Journal: The Journal of biological chemistry 20010803

Title: Selective and biphasic effect of the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal on N-methyl-D-aspartate channels.

Journal: Journal of neurochemistry 20010801

Title: Development and application of a self-referencing glucose microsensor for the measurement of glucose consumption by pancreatic beta-cells.

Journal: Analytical chemistry 20010801

Title: Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation.

Journal: Journal of neurochemistry 20010801

Title: Mitochondrial control of inducible nitric oxide production in stimulated RAW 264.7 macrophages.

Journal: Antioxidants & redox signaling 20010801

Title: Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain.

Journal: Blood 20010715

Title: Functional coupling between the caffeine/ryanodine-sensitive Ca2+ store and mitochondria in rat aortic smooth muscle cells.

Journal: The Biochemical journal 20010715

Title: Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A.

Journal: The Journal of biological chemistry 20010706

Title: Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease.

Journal: FEBS letters 20010706

Title: Functional coupling of PSST and ND1 subunits in NADH:ubiquinone oxidoreductase established by photoaffinity labeling.

Journal: Biochimica et biophysica acta 20010702

Title: Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolism.

Journal: Journal of cellular physiology 20010701

Title: Modulation of the extracellular divalent cation-inhibited non-selective conductance in cardiac cells by metabolic inhibition and by oxidants.

Journal: Journal of molecular and cellular cardiology 20010701

Title: Model for hypoxic pulmonary vasoconstriction involving mitochondrial oxygen sensing.

Journal: Circulation research 20010622

Title: Alterations in a redox oxygen sensing mechanism in chronic hypoxia.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20010601

Title: Five new prenylated stilbenes from the root bark of Lonchocarpus chiricanus.

Journal: Journal of natural products 20010601

Title: Investigation of calcium accumulation in mitochondria in cells undergoing apoptosis.

Journal: Biochemistry. Biokhimiia 20010601

Title: Mitochondrial respiration and triiodothyronine concentration in liver from postpubertal and adult rats.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010601

Title: Relaxant effect of 6-deoxyclitoriacetal on smooth muscle preparations.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010601

Title: Oxidative stress and lipid retention in vascular grafts: comparison between venous and arterial conduits.

Journal: Circulation 20010515

Title: Hypersensitization of tumor cells to glycolytic inhibitors.

Journal: Biochemistry 20010508

Title: In vitro effects of nicotine on mitochondrial respiration and superoxide anion generation.

Journal: Brain research 20010504

Title: Isolation and characterization of complex I, rotenone-sensitive NADH: ubiquinone oxidoreductase, from the procyclic forms of Trypanosoma brucei.

Journal: European journal of biochemistry 20010501

Title: Kinetic characterization of the rotenone-insensitive internal NADH: ubiquinone oxidoreductase of mitochondria from Saccharomyces cerevisiae.

Journal: Archives of biochemistry and biophysics 20010501

Title: ATP synthesis is coupled to rat liver mitochondrial RNA synthesis.

Journal: Molecular and cellular biochemistry 20010501

Title: Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria.

Journal: Free radical biology & medicine 20010415

Title: Calcium-dependent inhibition of L, N, and P/Q Ca2+ channels in chromaffin cells: role of mitochondria.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010415

Title: Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of Complex I.

Journal: Biochimica et biophysica acta 20010402

Title: A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

Journal: Journal of neurochemistry 20010401

Title: Regulation of respiration in rotenone-treated tobacco cell suspension cultures.

Journal: Planta 20010401

Title: Enhancement of oxidative damage to cultured cells and Caenorhabditis elegans by mitochondrial electron transport inhibitors.

Journal: IUBMB life 20010401

Title: Oxidative stress induced by ascorbate causes neuronal damage in an in vitro system.

Journal: Brain research 20010323

Title: Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha.

Journal: Oncogene 20010322

Title: Pharmacokinetics of deguelin, a cancer chemopreventive agent in rats.

Journal: Cancer chemotherapy and pharmacology 20010301

Title: Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN.

Journal: Archives of biochemistry and biophysics 20010215

Title: Chronic reduction in complex I function alters calcium signaling in SH-SY5Y neuroblastoma cells.

Journal: Brain research 20010209

Title: Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism.

Journal: Journal of neurochemistry 20010201

Title: Cytoplasmic Ca2+ at low submicromolar concentration stimulates mitochondrial metabolism in rat luteal cells.

Journal: Pflugers Archiv : European journal of physiology 20010201

Title: Interactions between mitochondrial proteins and lipid peroxidation products in the maintenance of the glomerular filtration barrier in the in vitro perfused kidney.

Journal: Experimental nephrology 20010101

Title: Differential effects of bcl-2 on cell death triggered under ATP-depleting conditions.

Journal: Experimental cell research 20010101

Title: Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease.

Journal: Journal of neurochemistry 20010101

Title: Computerized analysis of cytochemical reactions for dehydrogenases and oxygraphic studies as methods to evaluate the function of the mitochondrial sheath in rat spermatozoa.

Journal: Andrologia 20010101

Title: Cell attachment modulation by radiation from a pulsed light diode (lambda = 820 nm) and various chemicals.

Journal: Lasers in surgery and medicine 20010101

Title: Brain and liver mitochondria isolated from diabetic Goto-Kakizaki rats show different susceptibility to induced oxidative stress.

Journal: Diabetes/metabolism research and reviews 20010101

Title: Uncoupling effect of mercuric chloride on mitochondria isolated from an hepatic cell line.

Journal: Journal of applied toxicology : JAT 20010101

Title: Tumour necrosis factor induced an early release of superoxide and a late mitochondrial membrane depolarization in L929 cells. Increase in the production of superoxide is not sufficient to mimic the action of TNF.

Journal: Biological signals and receptors 20010101

Title: Nitroxide TEMPOL impairs mitochondrial function and induces apoptosis in HL60 cells.

Journal: Journal of cellular biochemistry 20010101

Title: Interleukin 1-induced cyclooxygenase and nitric oxide synthase gene expression in the rat dorsal root ganglia is modulated by antioxidants.

Journal: Neuroscience 20010101

Title: [Distribution of rat embryonal fibroblasts through cell cycle phases in the presence of inhibitors of active oxygen species formation and N-acetylcysteine].

Journal: Tsitologiia 20010101

Title: Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro.

Journal: In vitro cellular & developmental biology. Animal 20010101

Title: [The role of oxidative metabolism in energy supply for active potassium transport in erythrocytes of Lampetra fluviatilis].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20010101

Title: The existence and significance of redox-cycling ubiquinone in lysosomes.

Journal: Protoplasma 20010101

Title: Mitochondrial-derived oxidants and quartz activation of chemokine gene expression.

Journal: Advances in experimental medicine and biology 20010101

Title: Role of substrates in the regulation of mitochondrial function in situ.

Journal: IUBMB life 20010101

Title: Optical detection of mitochondrial NADH content in intact human myotubes.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20010101

Title: Chronic systemic pesticide exposure reproduces features of Parkinson's disease.

Journal: Nature neuroscience 20001201

Title: An early oxygen-dependent step is required for dexamethasone-induced apoptosis of immature mouse thymocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20001101

Title: Mitochondrial dysfunction of cardiomyocytes causing impairment of cellular energy metabolism induces apoptosis, and concomitant increase in cardiac endothelin-1 expression.

Journal: Journal of cardiovascular pharmacology 20001101

Title: Mitochondrial dysfunction increases expression of endothelin-1 and induces apoptosis through caspase-3 activation in rat cardiomyocytes in vitro.

Journal: Journal of cardiovascular pharmacology 20001101

Title: Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20000901

Title: Redox regulation of p53 during hypoxia.

Journal: Oncogene 20000810

Title: Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20000715

Title: GLUT-1 reduces hypoxia-induced apoptosis and JNK pathway activation.

Journal: American journal of physiology. Endocrinology and metabolism 20000501

Title: Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-kappaB activation induced by intracellular oxidative stress.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20000301

Title: Sodium arsenate induces overproduction of interleukin-1alpha in murine keratinocytes: role of mitochondria.

Journal: The Journal of investigative dermatology 19991101

Title: Diminished energy metabolism and enhanced apoptosis in livers of B6C3F1 mice treated with the antihepatocarcinogen rotenone.

Journal: Molecular and cellular biochemistry 19991101

Title: Inhibition of mitochondrial function in HL60 cells is associated with an increased apoptosis and expression of CD14.

Journal: Biochemical and biophysical research communications 19990924

Title: Overexpression of manganese superoxide dismutase protects against mitochondrial-initiated poly(ADP-ribose) polymerase-mediated cell death.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901

Title: Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate.

Journal: FEBS letters 19990820

Title: Induction of apoptosis in AK-5 cells by rotenone involves participation of caspases.

Journal: Indian journal of biochemistry & biophysics 19990401

Title: Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons.

Journal: The EMBO journal 19990215

Title: NADH: ubiquinone oxidoreductase inhibitors block induction of ornithine decarboxylase activity in MCF-7 human breast cancer cells.

Journal: Pharmacology & toxicology 19981101

Title: The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme.

Journal: The EMBO journal 19980817

Title: Reactive oxygen species regulate macrophage scavenger receptor type I, but not type II, in the human monocytic cell line THP-1.

Journal: Molecular pharmacology 19980601

Title: Quantitative study of mitochondrial complex I in platelets of parkinsonian patients.

Journal: Movement disorders : official journal of the Movement Disorder Society 19980101

Title: Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.

Journal: The Journal of biological chemistry 19971128

Title: Cooperative interception of neuronal apoptosis by BCL-2 and BAG-1 expression: prevention of caspase activation and reduced production of reactive oxygen species.

Journal: Journal of neurochemistry 19971101

Title: Regulation of ornithine decarboxylase induction by deguelin, a natural product cancer chemopreventive agent.

Journal: Cancer research 19970815

Title: Apoptosis of W256 carcinosarcoma cells of the monocytoid origin induced by NDGA involves lipid peroxidation and depletion of GSH: role of 12-lipoxygenase in regulating tumor cell survival.

Journal: Journal of cellular physiology 19970801

Title: Anomalous structure-activity relationships of 13-homo-13-oxarotenoids and 13-homo-13-oxadehyrorotenoids.

Journal: Chemical research in toxicology 19970801

Title: Pro- and anti-oxidant activities of the mitochondrial respiratory chain: factors influencing NAD(P)H-induced lipid peroxidation.

Journal: Biochimica et biophysica acta 19970116

Title: Increased manganese superoxide dismutase activity, protein, and mRNA levels and concurrent induction of tumor necrosis factor alpha in radiation-initiated Syrian hamster cells.

Journal: Molecular carcinogenesis 19961201

Title: Role of mitochondria in tributyltin-induced interleukin-1alpha production in murine keratinocytes.

Journal: The Journal of investigative dermatology 19961101

Title: Expression of the apoptosis-mediator Fas is enhanced by dysfunctional mitochondria.

Journal: Journal of biochemistry 19960901

Title: Redox regulation of manganese superoxide dismutase.

Journal: The American journal of physiology 19960701

Title: Antioxidants inhibit interleukin-1-induced cyclooxygenase and nitric-oxide synthase expression in rat mesangial cells. Evidence for post-transcriptional regulation.

Journal: The Journal of biological chemistry 19960517

Title: Rotenone, a mitochondrial NADH dehydrogenase inhibitor, induces cell surface expression of CD13 and CD38 and apoptosis in HL-60 cells.

Journal: Leukemia & lymphoma 19960201

Title: Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences.

Journal: The Journal of biological chemistry 19951208

Title: Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione.

Journal: Archives of biochemistry and biophysics 19950201

Title: Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease.

Journal: Journal of neurochemistry 19941101

Title: Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10.

Journal: Neuroscience letters 19940815

Title: Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

Journal: Journal of natural products 19910101

Title: Carcinogenesis with the insecticide rotenone.

Journal: Life sciences 19830221

Title: Rotenone: a possible environmental carcinogen?

Journal: European journal of cancer 19781201

Title: Properties of the 3-o-methyl-D-glucose transport system in Acholeplasma laidlawii.

Journal: Journal of bacteriology 19760101

Title: Pharmacological properties of rotenone.

Journal: Il Farmaco; edizione scientifica 19661001

Title: TOXICOLOGY OF ROTENONE.

Journal: Il Farmaco; edizione scientifica 19650401

Title: Determination of rotenone in pharmaceuticals.

Journal: Journal of the American Pharmaceutical Association. American Pharmaceutical Association 19590601

Title: Rotenone poisoning of swine.

Journal: Journal of the American Veterinary Medical Association 19570501

Title: [Derris and other rotenone plants].

Journal: Produits pharmaceutiques 19511001

Title: AMORPHA FRUTICOSA CONTAINS NO ROTENONE.

Journal: Science (New York, N.Y.) 19440204

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Tags:83-79-4 Molecular Formula|83-79-4 MDL|83-79-4 SMILES|83-79-4 Rotenone