+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Carboxes 832714-46-2
832714-46-2,MFCD12032117
Catalog No.:AA00G3KP

832714-46-2 | Isopropyl 4-{[1-(2-fluoro-4-methanesulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxy}piperidine-1-carboxylate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$63.00   $44.00
- +
5mg
98% by HPLC
in stock  
$224.00   $157.00
- +
10mg
98% by HPLC
in stock  
$335.00   $234.00
- +
25mg
98% by HPLC
in stock  
$637.00   $446.00
- +
50mg
98% by HPLC
in stock  
$1,040.00   $728.00
- +
100mg
96%
in stock  
$1,736.00   $1,215.00
- +
500mg
98% by HPLC
in stock  
$5,515.00   $3,861.00
- +
1000mg
98% by HPLC
in stock  
$8,787.00   $6,151.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3KP
Chemical Name:
Isopropyl 4-{[1-(2-fluoro-4-methanesulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxy}piperidine-1-carboxylate
CAS Number:
832714-46-2
Molecular Formula:
C21H24FN5O5S
Molecular Weight:
477.5092
MDL Number:
MFCD12032117
SMILES:
CC(OC(=O)N1CCC(CC1)Oc1ncnc2c1cnn2c1ccc(cc1F)S(=O)(=O)C)C
Properties
Computed Properties
 
Complexity:
788  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
9  
Rotatable Bond Count:
6  
XLogP3:
2.7  

Literature

Title: Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile.

Journal: Bioorganic & medicinal chemistry letters 20120215

Title: Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

Journal: Bioorganic & medicinal chemistry letters 20110515

Title: Semple G, et al. Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41.

Title: Bahirat UA, et, al. APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice. Eur J Pharmacol. 2017 Apr 15;801:35-45.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 832714-46-2
Building Blocks
More >
Tags:832714-46-2 Molecular Formula|832714-46-2 MDL|832714-46-2 SMILES|832714-46-2 Isopropyl 4-{[1-(2-fluoro-4-methanesulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxy}piperidine-1-carboxylate