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833-48-7,MFCD00003591
Catalog No.:AA00G2EF

833-48-7 | 10,11-Dihydro-5h-dibenzo[a,d]cycloheptene

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1g
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$112.00   $78.00
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5g
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$361.00   $253.00
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10g
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$610.00   $427.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00G2EF
Chemical Name:
10,11-Dihydro-5h-dibenzo[a,d]cycloheptene
CAS Number:
833-48-7
Molecular Formula:
C15H14
Molecular Weight:
194.2717
MDL Number:
MFCD00003591
SMILES:
c1ccc2c(c1)CCc1c(C2)cccc1
NSC Number:
86156
Properties
Computed Properties
 
Complexity:
186  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
XLogP3:
4.5  

Downstream Synthesis Route

[1]Gutsche;Johnson[JournaloftheAmericanChemicalSociety,1955,vol.77,p.5933]

[2]Kirmse,Wolfgang;Konrad,Wolfgang;Oezkir,IsmailS.[Tetrahedron,1997,vol.53,#29,p.9935-9964]

[3]Kirmse,Wolfgang;Konrad,Wolfgang;Oezkir,IsmailS.[Tetrahedron,1997,vol.53,#29,p.9935-9964]

[4]Kirmse,Wolfgang;Konrad,Wolfgang;Oezkir,IsmailS.[Tetrahedron,1997,vol.53,#29,p.9935-9964]

[5]Yamada,Takayuki;Saito,Kodai;Akiyama,Takahiko[AdvancedSynthesisandCatalysis,2016,vol.358,#1,p.62-66]

[6]Yamada,Takayuki;Saito,Kodai;Akiyama,Takahiko[AdvancedSynthesisandCatalysis,2016,vol.358,#1,p.62-66]

[1]Hicks;Han;Fry[TetrahedronLetters,2000,vol.41,#41,p.7817-7820]

[2]Liu,Guo-Bin;Zhao,Hong-Yun;Zhu,Jia-Da;He,Hong-Jie;Yang,Hong-Jie;Thiemann,Thies;Tashiro,Hideki;Tashiro,Masashi[SyntheticCommunications,2008,vol.38,#10,p.1651-1661]

[3]Mychajlyszyn;Protiva[CollectionofCzechoslovakChemicalCommunications,1959,vol.24,p.3955,3962]

[4]Treibs;Klinkhammer[ChemischeBerichte,1950,vol.83,p.367,471]

833-48-7    103057-10-9   
4-(10,11-Dihydro-5H-dibenzoa,dcyclohepten-5-ylmethyl)-1-trityl-1H-imidazole 

[1]EuropeanJournalofMedicinalChemistry,1990,vol.25,p.557-568

[1]Synlett,2009,p.117-121

[2]ChemCatChem,2018,vol.10,p.1096-1106

[3]OrganicLetters,2005,vol.7,p.4549-4552

[4]TetrahedronLetters,1998,vol.39,p.7247-7250

[5]Patent:US6362200,2002,B1.Locationinpatent:Example1

[6]Tetrahedron,2009,vol.65,p.1856-1858

[7]JournaloftheChemicalSociety.Chemicalcommunications,1980,p.643-644

[8]Synthesis,1987,p.915-917

[1]Wiggins,J.Mark[SyntheticCommunications,1988,vol.18,#7,p.741-750]

[2]Bordwell,FrederickG.;Drucker,GeorgeE.;Andersen,NielsH.;Denniston,AlanD.[JournaloftheAmericanChemicalSociety,1986,vol.108,#23,p.7310-7313]

Literature

Title: Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein.

Journal: Bioorganic & medicinal chemistry letters 20120201

Title: Chiral magnesium BINOL phosphate-catalyzed phosphination of imines: access to enantioenriched α-amino phosphine oxides.

Journal: Organic letters 20110415

Title: In vitro antiplasmodial activity of crude extracts of Tetrapleura tetraptera and Copaifera religiosa.

Journal: BMC research notes 20110101

Title: Radical reactivity of aza[60]fullerene: preparation of monoadducts and limitations.

Journal: The Journal of organic chemistry 20100618

Title: Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.

Journal: ChemMedChem 20090803

Title: Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors.

Journal: European journal of medicinal chemistry 20090601

Title: Use of acetylcholine binding protein in the search for novel alpha7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis.

Journal: Journal of medicinal chemistry 20090423

Title: Conformational effects in acid-mediated ring opening of epoxides: a prominent role of the oxirane Walsh orbital.

Journal: Organic letters 20080619

Title: Evidence for the involvement of the monoaminergic system in the antidepressant-like action of two 4-amine derivatives of 10,11-dihydro-5H-dibenzo [a,d] cycloheptane in mice evaluated in the tail suspension test.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080215

Title: Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists.

Journal: ChemMedChem 20071201

Title: Antidepressant-like profile of action of two 4-amine derivatives of 10,11-dihydro-5H-dibenzo [a,d] cycloheptane in mice evaluated in the forced swimming test.

Journal: Bioorganic & medicinal chemistry 20070215

Title: Two conformers of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene spiro-linked with homobenzoquinone epoxide.

Journal: Acta crystallographica. Section C, Crystal structure communications 20060301

Title: New bioactive prenylflavonoids and dibenzocycloheptene derivative from roots of Dendrolobium lanceolatum.

Journal: Journal of natural products 20040601

Title: A non-peptide antagonist unusually selective for the human form of the bradykinin B2 receptor.

Journal: International immunopharmacology 20031001

Title: Nonpeptide bradykinin B2 receptor antagonists: conversion of rodent-selective bradyzide analogues into potent, orally-active human bradykinin B2 receptor antagonists.

Journal: Journal of medicinal chemistry 20020523

Title: Second generation light-driven molecular motors. Unidirectional rotation controlled by a single stereogenic center with near-perfect photoequilibria and acceleration of the speed of rotation by structural modification.

Journal: Journal of the American Chemical Society 20020508

Title: Inhibitory effect of dibenzofuran and dibenzosuberol derivatives on rhinovirus replication in vitro; effective prevention of viral entry by dibenzosuberenone.

Journal: Antiviral research 19991215

Title: Topographic recognition of cyclic hydrocarbons and related compounds by receptors for androgens, estrogens, and glucocorticoids.

Journal: Journal of steroid biochemistry 19870101

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Tags:833-48-7 Molecular Formula|833-48-7 MDL|833-48-7 SMILES|833-48-7 10,11-Dihydro-5h-dibenzo[a,d]cycloheptene