Home Other Building Blocks 835621-07-3
835621-07-3,MFCD22417053
Catalog No.:AA00G3MY

835621-07-3 | Regorafenib HCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$7.00   $5.00
- +
5mg
98%
in stock  
$9.00   $7.00
- +
10mg
98%
in stock  
$12.00   $8.00
- +
25mg
98%
in stock  
$15.00   $11.00
- +
50mg
98%
in stock  
$19.00   $14.00
- +
1g
98%
in stock  
$162.00   $113.00
- +
5g
98%
in stock  
$710.00   $497.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3MY
Chemical Name:
Regorafenib HCl
CAS Number:
835621-07-3
Molecular Formula:
C21H16Cl2F4N4O3
Molecular Weight:
519.2764
MDL Number:
MFCD22417053
SMILES:
CNC(=O)c1nccc(c1)Oc1ccc(c(c1)F)NC(=O)Nc1ccc(c(c1)C(F)(F)F)Cl.Cl
Properties
Computed Properties
 
Complexity:
686  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
5  

Literature

Title: Wilhelm SM, et al. Regorafenib (BAY 73-4506): a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer, 2011, 129(1), 245-255.

Title: Heng DY, et al. Targeted therapy for metastatic renal cell carcinoma: current treatment and future directions. Ther Adv Med Oncol, 2010, 2(1), 39-49.

Title: Carr BI, et al. Fluoro-Sorafenib (Regorafenib) effects on hepatoma cells: growth inhibition, quiescence, and recovery. J Cell Physiol, 2013, 228(2), 292-297.

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SDS
Tags:835621-07-3 Molecular Formula|835621-07-3 MDL|835621-07-3 SMILES|835621-07-3 Regorafenib HCl